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The map label for this gene is creB [H]

Identifier: 119896995

GI number: 119896995

Start: 751848

End: 752555

Strand: Reverse

Name: creB [H]

Synonym: azo0704

Alternate gene names: 119896995

Gene position: 752555-751848 (Counterclockwise)

Preceding gene: 119896996

Following gene: 119896994

Centisome position: 17.2

GC content: 73.87

Gene sequence:

>708_bases
ATGTCCCGGCGCATCCTGATCGTCGATGACGAACCGGCGATCGCCGACATGCTCGCCTACGCGCTGCGCACCGAGGGCTA
CGAACCCGACTGCGTCGGCCTTGGCGGCGACGCGCTGGCGGCGCTGCGCGGCGGCGCCGACTACGCGCTCGTGATCCTCG
ACGTCGGCCTGCCCGACCAGTCCGGCTTCGACGTCTGCCGCGCGCTGCGGCGCGAATCCGACGTGCCGGTGATTTTCCTC
ACCGCGCGCAGCGACGAGGTGGACCGCATCGTCGGCCTCGAACTCGGCGCCGACGACTACGTGCCCAAGCCGTTCAGCCC
GCGCGAGGTCGCCTCGCGGGTGCGCGCCATCCTGCGCCGCGCGCGGCCGCAGCCGGCGGCTGTCGCGCCGGCGCCGGCGG
CGGAAACCTGCAGCGCGCCCTTCCACCACGATGCCGCCGGCGCCCGCATCGCCTACCACGGCGTGTGGCTGTCGCTGACG
CGCTACGAATACCGCCTGCTCGCCACCCTGCTCGACCGCCCCGGCCGGGTGCAGAGCCGCGCCCAGCTGATGGCCGACGT
CTGGCGCGACGCCGAGGACAGCCTGGAGCGCACGGTGGACGCCCACATCAAGACCCTGCGCGCCAAGCTGCGCGCGGTGC
GCGAGGACGAAGACCCGATCGAGACCCACCGCGGCCTGGGCTACAGCCTGCGCCCGGCGCAACGCTGA

Upstream 100 bases:

>100_bases
TCGGGGGCTCGGTGATGATCACCGCGCTCACCGACTCCGGCGGCTTCTTCATCTTCCTCGGCCTTGCCACGCTGTTCCTG
CTGTGAGCGGCGCGGCAGCA

Downstream 100 bases:

>100_bases
ATTCCGCACCGCAGGCGCCGCCGATGAACATCGCGATCCGCTTCTTCATCGGCTATTTCCTGATCGTCGGGCTCGCGGCC
TGGTTCGTGCTCAACATCTT

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSRRILIVDDEPAIADMLAYALRTEGYEPDCVGLGGDALAALRGGADYALVILDVGLPDQSGFDVCRALRRESDVPVIFL
TARSDEVDRIVGLELGADDYVPKPFSPREVASRVRAILRRARPQPAAVAPAPAAETCSAPFHHDAAGARIAYHGVWLSLT
RYEYRLLATLLDRPGRVQSRAQLMADVWRDAEDSLERTVDAHIKTLRAKLRAVREDEDPIETHRGLGYSLRPAQR

Sequences:

>Translated_235_residues
MSRRILIVDDEPAIADMLAYALRTEGYEPDCVGLGGDALAALRGGADYALVILDVGLPDQSGFDVCRALRRESDVPVIFL
TARSDEVDRIVGLELGADDYVPKPFSPREVASRVRAILRRARPQPAAVAPAPAAETCSAPFHHDAAGARIAYHGVWLSLT
RYEYRLLATLLDRPGRVQSRAQLMADVWRDAEDSLERTVDAHIKTLRAKLRAVREDEDPIETHRGLGYSLRPAQR
>Mature_234_residues
SRRILIVDDEPAIADMLAYALRTEGYEPDCVGLGGDALAALRGGADYALVILDVGLPDQSGFDVCRALRRESDVPVIFLT
ARSDEVDRIVGLELGADDYVPKPFSPREVASRVRAILRRARPQPAAVAPAPAAETCSAPFHHDAAGARIAYHGVWLSLTR
YEYRLLATLLDRPGRVQSRAQLMADVWRDAEDSLERTVDAHIKTLRAKLRAVREDEDPIETHRGLGYSLRPAQR

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=52.6315789473684, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=40.4444444444444, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=37.7682403433476, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789809, Length=238, Percent_Identity=34.8739495798319, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=37.3390557939914, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=33.1858407079646, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=36.7521367521368, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=36.6379310344828, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI87082012, Length=238, Percent_Identity=34.453781512605, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=35.5263157894737, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=38.034188034188, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=32.618025751073, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=35.1931330472103, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=27.0042194092827, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=36.036036036036, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25922; Mature: 25791

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRILIVDDEPAIADMLAYALRTEGYEPDCVGLGGDALAALRGGADYALVILDVGLPDQ
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCCEEEEEEEECCCCC
SGFDVCRALRRESDVPVIFLTARSDEVDRIVGLELGADDYVPKPFSPREVASRVRAILRR
CCHHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
ARPQPAAVAPAPAAETCSAPFHHDAAGARIAYHGVWLSLTRYEYRLLATLLDRPGRVQSR
CCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEHEEEEHHHHHHHHHHHHHCCCCCHHHH
AQLMADVWRDAEDSLERTVDAHIKTLRAKLRAVREDEDPIETHRGLGYSLRPAQR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SRRILIVDDEPAIADMLAYALRTEGYEPDCVGLGGDALAALRGGADYALVILDVGLPDQ
CCEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCCEEEEEEEECCCCC
SGFDVCRALRRESDVPVIFLTARSDEVDRIVGLELGADDYVPKPFSPREVASRVRAILRR
CCHHHHHHHHHCCCCCEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
ARPQPAAVAPAPAAETCSAPFHHDAAGARIAYHGVWLSLTRYEYRLLATLLDRPGRVQSR
CCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEHEEEEHHHHHHHHHHHHHCCCCCHHHH
AQLMADVWRDAEDSLERTVDAHIKTLRAKLRAVREDEDPIETHRGLGYSLRPAQR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]