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The map label for this gene is virG [H]

Identifier: 119896984

GI number: 119896984

Start: 735949

End: 736680

Strand: Reverse

Name: virG [H]

Synonym: azo0693

Alternate gene names: 119896984

Gene position: 736680-735949 (Counterclockwise)

Preceding gene: 119896985

Following gene: 119896983

Centisome position: 16.83

GC content: 68.17

Gene sequence:

>732_bases
ATGAGTGCGACCCGACCCGAGGCCAGTCCGCCGACCATCTTCGTCCTGGAGGACGAGCCGGACATTGCGCGGCTGATCTG
CAGCAGCCTGACCGAGTACGGTTTCCGCTGCGAACATCTGACGACGGGGCGCCAGTTGCTGCAGCGCGCGCGCCAGCAGA
CGCCCGACCTGTGCATCGTCGACCTCGGCCTGCCCGACATGGACGGCATGCAGGTGGTGCGCGAGCTGCAGGACGGCAGC
CCGTGCGCGGTACTGATCCTGACCGGCCGCAACGATGTGACCGACCGCGTGCTCGGTCTGGAGCTGGGGGCGGACGACTA
CATCGTCAAGCCGTTCGAGCCGCGCGAGCTGGTCGCACGGGTGCGTTCCATCCTGCGCCGCTACCAGCGCTCGGCGCCGC
CAGAGACCAGCGCCGCGGAGAAGACCGTCGCCCGTTTCGCCGGCTGGACCTTCGACGGCGGGCGGTTGACCATGACCGCG
CCGGACGGCCGGGAGGTGAATCTCTCTGCCGCCGAGGCGAGCCTGCTGGCGGTGCTGTTGCGGCGGCCGAACAAGATTTT
TTCGCGCGAACAGTTGCTGGGCGAGCGCGACGTCGATCCCTTCGACCGCAGCATCGACGTACGCATCTCGCGCCTGCGCC
GCAAGCTCGACGACGACCCGCAGAATCCCCGGCTGATCAAGACGGTATACGGGGCGGGGTATCTGTTTGCGGCGCAGGTG
AGTTGGGAGTAG

Upstream 100 bases:

>100_bases
CGCCCCCGGCCGACATTCCGGTGTTGCGCAAACCTTTCGATCAGGCGGCGCTGGCCGCCGCGCTGCAGAACATCCATCCG
CCGCAGGAGCACGAACCCTC

Downstream 100 bases:

>100_bases
CGGGTTACGGGACGACCGCTTCCCCCGAGGTGACCGGACGACGGGGCGACGGTGCAAAGCGGACGCTACCGGGCTGAGCG
GTTTTACTCCCTCCCCTTCA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSATRPEASPPTIFVLEDEPDIARLICSSLTEYGFRCEHLTTGRQLLQRARQQTPDLCIVDLGLPDMDGMQVVRELQDGS
PCAVLILTGRNDVTDRVLGLELGADDYIVKPFEPRELVARVRSILRRYQRSAPPETSAAEKTVARFAGWTFDGGRLTMTA
PDGREVNLSAAEASLLAVLLRRPNKIFSREQLLGERDVDPFDRSIDVRISRLRRKLDDDPQNPRLIKTVYGAGYLFAAQV
SWE

Sequences:

>Translated_243_residues
MSATRPEASPPTIFVLEDEPDIARLICSSLTEYGFRCEHLTTGRQLLQRARQQTPDLCIVDLGLPDMDGMQVVRELQDGS
PCAVLILTGRNDVTDRVLGLELGADDYIVKPFEPRELVARVRSILRRYQRSAPPETSAAEKTVARFAGWTFDGGRLTMTA
PDGREVNLSAAEASLLAVLLRRPNKIFSREQLLGERDVDPFDRSIDVRISRLRRKLDDDPQNPRLIKTVYGAGYLFAAQV
SWE
>Mature_242_residues
SATRPEASPPTIFVLEDEPDIARLICSSLTEYGFRCEHLTTGRQLLQRARQQTPDLCIVDLGLPDMDGMQVVRELQDGSP
CAVLILTGRNDVTDRVLGLELGADDYIVKPFEPRELVARVRSILRRYQRSAPPETSAAEKTVARFAGWTFDGGRLTMTAP
DGREVNLSAAEASLLAVLLRRPNKIFSREQLLGERDVDPFDRSIDVRISRLRRKLDDDPQNPRLIKTVYGAGYLFAAQVS
WE

Specific function: Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expres

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.9055793991416, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.117903930131, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=37.9746835443038, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=38.2978723404255, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=38.8646288209607, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=34.6153846153846, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.4978165938865, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI2367329, Length=179, Percent_Identity=39.6648044692737, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=34.7826086956522, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.4978165938865, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=34.1991341991342, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=35.1464435146443, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=30.1310043668122, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=29.2452830188679, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=30.3703703703704, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27255; Mature: 27124

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATRPEASPPTIFVLEDEPDIARLICSSLTEYGFRCEHLTTGRQLLQRARQQTPDLCIV
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEE
DLGLPDMDGMQVVRELQDGSPCAVLILTGRNDVTDRVLGLELGADDYIVKPFEPRELVAR
ECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHEEEEECCCCCEECCCCHHHHHHH
VRSILRRYQRSAPPETSAAEKTVARFAGWTFDGGRLTMTAPDGREVNLSAAEASLLAVLL
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCEECCCEEEEECCCCCEEECHHHHHHHHHHHH
RRPNKIFSREQLLGERDVDPFDRSIDVRISRLRRKLDDDPQNPRLIKTVYGAGYLFAAQV
HCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEE
SWE
ECC
>Mature Secondary Structure 
SATRPEASPPTIFVLEDEPDIARLICSSLTEYGFRCEHLTTGRQLLQRARQQTPDLCIV
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEE
DLGLPDMDGMQVVRELQDGSPCAVLILTGRNDVTDRVLGLELGADDYIVKPFEPRELVAR
ECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHEEEEECCCCCEECCCCHHHHHHH
VRSILRRYQRSAPPETSAAEKTVARFAGWTFDGGRLTMTAPDGREVNLSAAEASLLAVLL
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCEECCCEEEEECCCCCEEECHHHHHHHHHHHH
RRPNKIFSREQLLGERDVDPFDRSIDVRISRLRRKLDDDPQNPRLIKTVYGAGYLFAAQV
HCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEE
SWE
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]