Click here to switch to the map view.

The map label for this gene is csrD [H]

Identifier: 119896943

GI number: 119896943

Start: 681161

End: 683074

Strand: Reverse

Name: csrD [H]

Synonym: azo0652

Alternate gene names: 119896943

Gene position: 683074-681161 (Counterclockwise)

Preceding gene: 119896944

Following gene: 119896936

Centisome position: 15.61

GC content: 72.2

Gene sequence:

>1914_bases
ATGTCCCTGATCAAGCAACTCTGGATCGCCATCGCCCTGGTCACCGTGCTCTCGCTCGGCGGCAGCTTCGTCGTCAGCAC
ACTGGCGGCGCGCCACTACCTGCAACAGGAGCTGGCGGTGAAGAACATGGACAACGCCGCCTCGCTCGCGCTGTCGCTGT
CGCAGATGCCGAAGGACCCGGTGACGGTGGAGCTGCAGGTGGCGGCGCAGTTCGACACCGGCCACTACCGGCTGATCCGC
CTGACCGGTGCGAGCGGCGAGGTGCTGGTCGAGCGCAGTTTCGACGGCGCCGAAGCGAGCGCGCCGGCGTGGTTCATGGC
GCTGGTGCCGATCGAGACCCAGCCCGGTGTCGCCCAGGTGCAGGACGGCTGGCATCAGTTCGGTACGCTGTCGGTCGAGA
CCCACAGCCGCTACGCCTACGACTCGCTGTGGCAGGCGACGCGCCAGCTGCTGATGTGGTTCGTCGGCGGCGGCCTGCTG
ACCGGGCTGGTCGGCACCCTCGCGCTGAAGTTCATCACCCGTCCGCTGGACCGCATGGTCGAGCAGGCCGAGGCGATCGG
CGGGCGCCGCTTCGTCACCACGCCGGAGCCGCGCACGCTGGAGTTCCGCAGCGTGGTGCGGGCGATGAACGCGCTCTCGG
ACCGCGTGCGCAGCATGCTGGCCGAGGAATCCCAGCGTCTGGAGGCGCTGCGGCGCCAGACCCAGCAGGACGAACTCACC
GGTCTTTTCAACCGCGCCCAACTGCTGCGCCAGCTCGACGCCGCGCTGAGCGGCGAAGCGAGCGCGGACGGCGTGATGCT
GATCGCGCGCGTCGCCGACCTTGCCGCACTCAACCAGCGCCTGGGCCGGTTGGCGGTGGACAACACGCTGCGCACGCTGG
CCGGGGCGCTCGGCGGCTTCACCGCGGCCCACCCGGGATGGGACTGCGGGCGCCTGAACGCCACCGACTTCGCGCTGATC
GCACCGGGCGCGGTGGACGCCGCGGCGCTGGCCGACGAACTCGCGCACACCCTCGACACCGCGCTGACGCCGGTGAGCGA
GATTCACCGCCTGCATCTCGCCGCCACGCCCTATGCGGCGCAGGAGGCGCGCAGCGCGGTGCTGACCCGGCTGGATGGCG
TGCTCGCGGCAAGCGAGCTGCACGGCGACCGCGCGGTGCGTGTCGGCATCGCCGATGGTGCCGAGGCCGGCCCGCAGGGC
GCGGGCGAATGGCGCCGCCTGCTCGACGCCGCGCTCGCGGCGGGACACATCGAGCTGGCGCGCTTCCCGGTGATCGACCG
CGACGGCGCGCTGCTCCACGACGAAGCGCCGGTGCGCCTCGCGCTGGACGGCAACTGGTACGCCGCCGGACGCTTCATGC
CGTGGGCGGCGCGGCTGGGCATGATGGTGGCGGTGGATACCGCCGTGGCGCGCACCGCACTGGCGGCGCTGGCGGCGGAC
GGCGCGGCCACGCTGGCGATCAACCTGTCGGTGGAGGCGCTGCGCGACGCCGGCTTCCGCGACGCCCTCTATCACCTGCT
GGAATCCGACCCCGCGGCCGCACGCCGGCTGTGGATCGACGTGCCGGAACACGCGGCGCTGCAATATCAGGTGGAGTTCC
GCGCGCTGTGCCTCGCGCTGCGCCCGCTCGGCTGCCGCGTCGGCCTCAAGCACGCGGGGCCGGCGTTCTCGCGCATCGCC
GAGCTGCACGACCTCGGGCTGGACTACATCAAGGTGGCTGCGGCCTTCGTGCGCGACATCGACAACTCGCCGGGCAACAT
GGCCTTCGTGCGCGGGCTGTGCACCATCGCCCACTCGATCGGCCTGCAGACGATTGCCGAAGGCGTCAGCACCGAGGCGG
AGCGCGATGCGCTGCCCGACCTCGGCCTGGACGGCATGACCGGCCCCGCGATCCGCCGCCCGCAGGCGGCTTGA

Upstream 100 bases:

>100_bases
GCGCGCCTGTCGCGCTGGCGCGACGCGCTCGACCGCATGCGGCGCGAAGGCCTGACGCTGCCCTGAACTCATCCCGAATC
CCCACCGGAACGACCCGCCC

Downstream 100 bases:

>100_bases
TCAGAGCAGCCCGGCGTCGTCGTCGAGCAGGCTGTCGCTGTTCAGGGACTGGCGCAGCGACCGCCGCTGCAGCAGGCGGT
TCTGCGCCGGCAGCGGCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSLIKQLWIAIALVTVLSLGGSFVVSTLAARHYLQQELAVKNMDNAASLALSLSQMPKDPVTVELQVAAQFDTGHYRLIR
LTGASGEVLVERSFDGAEASAPAWFMALVPIETQPGVAQVQDGWHQFGTLSVETHSRYAYDSLWQATRQLLMWFVGGGLL
TGLVGTLALKFITRPLDRMVEQAEAIGGRRFVTTPEPRTLEFRSVVRAMNALSDRVRSMLAEESQRLEALRRQTQQDELT
GLFNRAQLLRQLDAALSGEASADGVMLIARVADLAALNQRLGRLAVDNTLRTLAGALGGFTAAHPGWDCGRLNATDFALI
APGAVDAAALADELAHTLDTALTPVSEIHRLHLAATPYAAQEARSAVLTRLDGVLAASELHGDRAVRVGIADGAEAGPQG
AGEWRRLLDAALAAGHIELARFPVIDRDGALLHDEAPVRLALDGNWYAAGRFMPWAARLGMMVAVDTAVARTALAALAAD
GAATLAINLSVEALRDAGFRDALYHLLESDPAAARRLWIDVPEHAALQYQVEFRALCLALRPLGCRVGLKHAGPAFSRIA
ELHDLGLDYIKVAAAFVRDIDNSPGNMAFVRGLCTIAHSIGLQTIAEGVSTEAERDALPDLGLDGMTGPAIRRPQAA

Sequences:

>Translated_637_residues
MSLIKQLWIAIALVTVLSLGGSFVVSTLAARHYLQQELAVKNMDNAASLALSLSQMPKDPVTVELQVAAQFDTGHYRLIR
LTGASGEVLVERSFDGAEASAPAWFMALVPIETQPGVAQVQDGWHQFGTLSVETHSRYAYDSLWQATRQLLMWFVGGGLL
TGLVGTLALKFITRPLDRMVEQAEAIGGRRFVTTPEPRTLEFRSVVRAMNALSDRVRSMLAEESQRLEALRRQTQQDELT
GLFNRAQLLRQLDAALSGEASADGVMLIARVADLAALNQRLGRLAVDNTLRTLAGALGGFTAAHPGWDCGRLNATDFALI
APGAVDAAALADELAHTLDTALTPVSEIHRLHLAATPYAAQEARSAVLTRLDGVLAASELHGDRAVRVGIADGAEAGPQG
AGEWRRLLDAALAAGHIELARFPVIDRDGALLHDEAPVRLALDGNWYAAGRFMPWAARLGMMVAVDTAVARTALAALAAD
GAATLAINLSVEALRDAGFRDALYHLLESDPAAARRLWIDVPEHAALQYQVEFRALCLALRPLGCRVGLKHAGPAFSRIA
ELHDLGLDYIKVAAAFVRDIDNSPGNMAFVRGLCTIAHSIGLQTIAEGVSTEAERDALPDLGLDGMTGPAIRRPQAA
>Mature_636_residues
SLIKQLWIAIALVTVLSLGGSFVVSTLAARHYLQQELAVKNMDNAASLALSLSQMPKDPVTVELQVAAQFDTGHYRLIRL
TGASGEVLVERSFDGAEASAPAWFMALVPIETQPGVAQVQDGWHQFGTLSVETHSRYAYDSLWQATRQLLMWFVGGGLLT
GLVGTLALKFITRPLDRMVEQAEAIGGRRFVTTPEPRTLEFRSVVRAMNALSDRVRSMLAEESQRLEALRRQTQQDELTG
LFNRAQLLRQLDAALSGEASADGVMLIARVADLAALNQRLGRLAVDNTLRTLAGALGGFTAAHPGWDCGRLNATDFALIA
PGAVDAAALADELAHTLDTALTPVSEIHRLHLAATPYAAQEARSAVLTRLDGVLAASELHGDRAVRVGIADGAEAGPQGA
GEWRRLLDAALAAGHIELARFPVIDRDGALLHDEAPVRLALDGNWYAAGRFMPWAARLGMMVAVDTAVARTALAALAADG
AATLAINLSVEALRDAGFRDALYHLLESDPAAARRLWIDVPEHAALQYQVEFRALCLALRPLGCRVGLKHAGPAFSRIAE
LHDLGLDYIKVAAAFVRDIDNSPGNMAFVRGLCTIAHSIGLQTIAEGVSTEAERDALPDLGLDGMTGPAIRRPQAA

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=418, Percent_Identity=24.1626794258373, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788849, Length=235, Percent_Identity=26.8085106382979, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87082096, Length=236, Percent_Identity=24.1525423728814, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790496, Length=230, Percent_Identity=25.6521739130435, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 68188; Mature: 68057

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50885 HAMP ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIKQLWIAIALVTVLSLGGSFVVSTLAARHYLQQELAVKNMDNAASLALSLSQMPKDP
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VTVELQVAAQFDTGHYRLIRLTGASGEVLVERSFDGAEASAPAWFMALVPIETQPGVAQV
CEEEEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCHHHH
QDGWHQFGTLSVETHSRYAYDSLWQATRQLLMWFVGGGLLTGLVGTLALKFITRPLDRMV
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAEAIGGRRFVTTPEPRTLEFRSVVRAMNALSDRVRSMLAEESQRLEALRRQTQQDELT
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFNRAQLLRQLDAALSGEASADGVMLIARVADLAALNQRLGRLAVDNTLRTLAGALGGF
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TAAHPGWDCGRLNATDFALIAPGAVDAAALADELAHTLDTALTPVSEIHRLHLAATPYAA
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
QEARSAVLTRLDGVLAASELHGDRAVRVGIADGAEAGPQGAGEWRRLLDAALAAGHIELA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
RFPVIDRDGALLHDEAPVRLALDGNWYAAGRFMPWAARLGMMVAVDTAVARTALAALAAD
HCCEECCCCCEEECCCCEEEEECCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCC
GAATLAINLSVEALRDAGFRDALYHLLESDPAAARRLWIDVPEHAALQYQVEFRALCLAL
CCEEEEEEEEHHHHHCCCHHHHHHHHHCCCCHHHHHEEEECCCCCEEEEHHHHHHHHHHH
RPLGCRVGLKHAGPAFSRIAELHDLGLDYIKVAAAFVRDIDNSPGNMAFVRGLCTIAHSI
HCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GLQTIAEGVSTEAERDALPDLGLDGMTGPAIRRPQAA
HHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLIKQLWIAIALVTVLSLGGSFVVSTLAARHYLQQELAVKNMDNAASLALSLSQMPKDP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
VTVELQVAAQFDTGHYRLIRLTGASGEVLVERSFDGAEASAPAWFMALVPIETQPGVAQV
CEEEEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCHHHH
QDGWHQFGTLSVETHSRYAYDSLWQATRQLLMWFVGGGLLTGLVGTLALKFITRPLDRMV
HHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQAEAIGGRRFVTTPEPRTLEFRSVVRAMNALSDRVRSMLAEESQRLEALRRQTQQDELT
HHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFNRAQLLRQLDAALSGEASADGVMLIARVADLAALNQRLGRLAVDNTLRTLAGALGGF
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TAAHPGWDCGRLNATDFALIAPGAVDAAALADELAHTLDTALTPVSEIHRLHLAATPYAA
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
QEARSAVLTRLDGVLAASELHGDRAVRVGIADGAEAGPQGAGEWRRLLDAALAAGHIELA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
RFPVIDRDGALLHDEAPVRLALDGNWYAAGRFMPWAARLGMMVAVDTAVARTALAALAAD
HCCEECCCCCEEECCCCEEEEECCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCC
GAATLAINLSVEALRDAGFRDALYHLLESDPAAARRLWIDVPEHAALQYQVEFRALCLAL
CCEEEEEEEEHHHHHCCCHHHHHHHHHCCCCHHHHHEEEECCCCCEEEEHHHHHHHHHHH
RPLGCRVGLKHAGPAFSRIAELHDLGLDYIKVAAAFVRDIDNSPGNMAFVRGLCTIAHSI
HCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GLQTIAEGVSTEAERDALPDLGLDGMTGPAIRRPQAA
HHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]