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The map label for this gene is ruvA

Identifier: 119896893

GI number: 119896893

Start: 629785

End: 630384

Strand: Reverse

Name: ruvA

Synonym: azo0602

Alternate gene names: 119896893

Gene position: 630384-629785 (Counterclockwise)

Preceding gene: 119896896

Following gene: 119896892

Centisome position: 14.41

GC content: 69.33

Gene sequence:

>600_bases
ATGATCGGACGCATCAGCGGCCTGCTGCTCGAAAAGAACCCGCCGCAGATCCTGGTCGACGCCCACGGCGTCGGCTACGA
ACTCGAAGTGCCGATGAGCACCTTCTACGGCCTGCCCGCCACCGGCACCCAGGTCAGCCTGCACACCCACCTCGCGATCC
GCGAGGACGGCCACTTCCTGTACGGCTTCGCCACCGACGAGGAGCGCACCGCATTCCGCCAGTTGCTCAAGGTCTCCGGC
ATCGGCGCGCGCACCGCGCTCGCGGTGCTGTCGGGGCTGTCGGTGTCCGACCTCGCGCAGGCGGTGGCGCTGCAGGAAGC
CGGACGGCTGGTGAAGATTCCCGGTATCGGCAAGAAGACCGCGGAACGCCTGCTGCTGGAGCTGCGCGACAAGCTCGGCA
AGGCGTTGCCGCAGGTCGCCGGCGCGCGGCTGGCCGCGGTCGCAGGGGGTGCGCCGGACGCGAAGAGCGACATCCTCAAT
GCGCTGCTCGCGCTCGGCTACAACGAGAAGGAAGCGCTCGGCGCGATGAAGGGCCTGGCCGAGGACACCGGCGTCTCCGA
CGGCATCCGCCAGGCGCTCAAGCTGCTGTCCAAGGCCTGA

Upstream 100 bases:

>100_bases
ACACCCGCAGCCGCCGGGCGCTCGCGGACGCCCGGGCCAGCCGCTACACTCCAGCCCCATCCTTCGCCCGCGGCCGCGCC
GCACCCACAGGAAGACCCGA

Downstream 100 bases:

>100_bases
ACAAAACCACAGTCATGCGCACCCCGGCAGGCGTCCGAGCGGCTAAACTCTCGCCATGATCGAAACCGACAAGCTCCGCG
CCGCCGCGCCCGAGCGCCTG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIGRISGLLLEKNPPQILVDAHGVGYELEVPMSTFYGLPATGTQVSLHTHLAIREDGHFLYGFATDEERTAFRQLLKVSG
IGARTALAVLSGLSVSDLAQAVALQEAGRLVKIPGIGKKTAERLLLELRDKLGKALPQVAGARLAAVAGGAPDAKSDILN
ALLALGYNEKEALGAMKGLAEDTGVSDGIRQALKLLSKA

Sequences:

>Translated_199_residues
MIGRISGLLLEKNPPQILVDAHGVGYELEVPMSTFYGLPATGTQVSLHTHLAIREDGHFLYGFATDEERTAFRQLLKVSG
IGARTALAVLSGLSVSDLAQAVALQEAGRLVKIPGIGKKTAERLLLELRDKLGKALPQVAGARLAAVAGGAPDAKSDILN
ALLALGYNEKEALGAMKGLAEDTGVSDGIRQALKLLSKA
>Mature_199_residues
MIGRISGLLLEKNPPQILVDAHGVGYELEVPMSTFYGLPATGTQVSLHTHLAIREDGHFLYGFATDEERTAFRQLLKVSG
IGARTALAVLSGLSVSDLAQAVALQEAGRLVKIPGIGKKTAERLLLELRDKLGKALPQVAGARLAAVAGGAPDAKSDILN
ALLALGYNEKEALGAMKGLAEDTGVSDGIRQALKLLSKA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=200, Percent_Identity=43.5, Blast_Score=169, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_AZOSB (A1K314)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932106.1
- ProteinModelPortal:   A1K314
- SMR:   A1K314
- STRING:   A1K314
- GeneID:   4609836
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0602
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   A1K314
- ProtClustDB:   PRK00116
- BioCyc:   ASP62928:AZO0602-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20831; Mature: 20831

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRISGLLLEKNPPQILVDAHGVGYELEVPMSTFYGLPATGTQVSLHTHLAIREDGHFL
CCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCEEEEEEEEEEECCCCEE
YGFATDEERTAFRQLLKVSGIGARTALAVLSGLSVSDLAQAVALQEAGRLVKIPGIGKKT
EEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCHHH
AERLLLELRDKLGKALPQVAGARLAAVAGGAPDAKSDILNALLALGYNEKEALGAMKGLA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
EDTGVSDGIRQALKLLSKA
HHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRISGLLLEKNPPQILVDAHGVGYELEVPMSTFYGLPATGTQVSLHTHLAIREDGHFL
CCCCCCCEEECCCCCEEEEECCCCCEEEECCHHHHCCCCCCCCEEEEEEEEEEECCCCEE
YGFATDEERTAFRQLLKVSGIGARTALAVLSGLSVSDLAQAVALQEAGRLVKIPGIGKKT
EEEECCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCHHH
AERLLLELRDKLGKALPQVAGARLAAVAGGAPDAKSDILNALLALGYNEKEALGAMKGLA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
EDTGVSDGIRQALKLLSKA
HHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA