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The map label for this gene is fadB2 [H]

Identifier: 119896759

GI number: 119896759

Start: 503770

End: 506154

Strand: Direct

Name: fadB2 [H]

Synonym: azo0468

Alternate gene names: 119896759

Gene position: 503770-506154 (Clockwise)

Preceding gene: 119896758

Following gene: 119896760

Centisome position: 11.51

GC content: 72.03

Gene sequence:

>2385_bases
ATGCTGATACGCAAGGTGGCGGTGCTCGGCGCCGGCGTCATGGGGGCGCAGATCGCCGCGCACTGCGCCAACGCCGGTTT
GCAGGTGATCCTGTTCGATCTGCCGGCGCCGGCGGGGCCGCCCGATACGGTGGTGGAAAAGGCGATTGCCGGGCTGGCGA
AGCTGGACCCGGCGCCGCTCGCGAGCCGCGCGCTCGCCGCCGCGATCACGCCCGCCAACTACGCCAGCGACCTTGCCCGG
CTGGGCGAGTGCGAGCTGGTGATCGAGGCGATCGCCGAGAAGATGGCGTGGAAGCTGGACCTCTACGCCAAGGTGGCGCC
GCATCTGGCGCCCGGCGCGGTGTTCGCTTCCAACACCTCGGGGCTGTCGATCGCCCGCCTCGCCGAGGGCCTGCCGGCGG
CGCTGCGGCCGCGCTTCTGCGGCGTGCATTTCTTCAACCCGCCGCGCTACATGGCGCTGGTGGAACTGATCCCCGCGCCG
GACACCGACCCGGCCCTGCTCGACGCGCTCGAAGGCTGGCTGACCACGCGGCTGGGCAAGCGCATCGTGCGCGCCCGCGA
CACCCCGAACTTCATCGCCAACCGCATCGGCGTGTTTTCGGTGCTGGCGGTGATGCACCACACCACCCGGCTGGGGCTCG
CGTTCGACGAGGTGGATGCGATCACCGGGCCGCGCATCGGCCGGCCCAAGAGCGCCACCTACCGCACCGCCGACCTGGTG
GGCCTCGACACGCTCGCCCATGTGGTCGGCACCATGCAGGACGGCCTGCCGGACGACCCCTGGCATGGCCACTTCGCGCT
GCCCGGCTGGCTCGACACCCTGATCGCCAACGGCGCGCTCGGGCAGAAGACCCAGGCCGGCATCTACCGCAAGGAAGGCC
GCCAGATCCTCGTGTTCGAACCCGCCCAGCTGGATTACCGTGCCGCGGCCGGTGAGGTTGCGGTGGAGGTGGCGGAGATC
CTCGCGCTGCGCGACCCGGCCGAGAAGCTGGCCGGACTCGCCGCCTGCGCCCACCCGCAGGCGCAACTGCTGTGGTCCAG
TTTCCGCGACGTCTTCCACTACTGCGCCTACCACCTGGAGCACATCGCCGACAACGCGCGCGATGTGGATAGCGCGATGC
GCTGGGGTTTCGGCTGGGCGCAAGGACCGTTCGAAACCTGGCAGGCAGCGGGCTGGGCCGAGGTGGCGGCGGCGATCCGC
GAGGACATCGCCGCCGGGCGCGCGATGAGCGACGCGCCGCTGCCCGACTGGGTGTTCGAACGCGACGGCGTGCATGCGGC
GGGCGGGTCTTGGAGCCCCGCGGCCGCGGCGCTGCAGCCGCGCCCGGCGCTGCCGGTCTATGGGCGCCAGTTGCAGGCCG
AGCGGCTGGTCGGCGAGGCGCCCCCCGAGCGTGGCGAAACCCTGTGGGAGTGCGGCGAACGCGGCGACGGCGTGCGTCTG
TGGCGGCTGCCGGCGCTGGATGCCGGCATCGGCGTGCTGTCGTTCAAATCCAAGATGCACACGGTGGGCGGCGCGGTGCT
GGAGGGCGTGCTGGAGGCGGTGGCGCGCGCCCAGCGTGATCTCGACGGGCTGGTGCTGTGGCAACCGGCGCCGTTTTCGG
TCGGCGCCAACCTGCAGCAGGTGGGCGAGGCCTGCAGCGCCGGCGAGTTCGCGCGCCTGGAGCAGACCGTGGCCCGCTTC
CAGCAGGCCGCGCTGGCGCTGCGCCACGCACAGGTGCCGGTGGTGGCCGCGGTGGAGGGCATGGCGCTGGCGGGCGGCTG
CGAGTTCCTGATGCACTGCGCCCACCGCGTGCTCGCGCTGGAAAGCTACGTGGGCCTGGTGGAAGCCGGCGTCGGCCTGA
TCCCGGCCGGCGGCGGCAGCAAGCAGTTTGCGCTGCAGGCCCACCGGCTGGCGCAGCGTGCGGCCGGGGGCGACGTGTTT
CCGTTCATCCAGCGCAGCTTCGAGACCATCGCCAAGGCCACCGTGGCCAAGAGCGCGCACGAGGCGGTGCAACTCGGCTT
CGCCGCGCCCGGCGATGACATCGTGCTCCATGCGCAGGAGGTGCTGTACGTGGCGCTCCGTCGCGCCCGCGCACTGGCCG
AAGCCGGCTGGCACCCGCCGCTGCCCGAACGCGCGGTGGTGGTCGCCGGGCGCAACGGCATTGCCACCTGCGAGCTGATG
CTGGTGAACATGGCCGAGGGCGGTTTCATCTCGGCGCACGACTACAAGGTTGCCAAGGCCGCCGCGACCGCGCTGTGCGG
CGGCGAGGTGGACACCAACGCGCGGGTGAGCGAGCAGTGGATCCTGGACGTGGAGCGGGCGCTGTTCGTGGAACTGCTGC
AGACCGAGGCGACGCAGCAGCGGATCGCGCACATGCTGCGGACGGGGAAGCCGTTGCGGAATTGA

Upstream 100 bases:

>100_bases
GTACGATTCCAGCGTGTGGATACTGGGCGCGCAGTACTCGGTGGCGTTCTAGCGGATCGCGGCACGCCGCCGCACAGCAG
GGGGGATGACGGTGAGCAAG

Downstream 100 bases:

>100_bases
GGGGCCGTTAGGGGGGCGTGGACGCGCGCCGGGCTGCGTGGTGGCGCGATTCGGCAGGACCATGGGCAGGAGGAGCGGGA
TCCGGTCTGGCGCGGCCCTT

Product: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MLIRKVAVLGAGVMGAQIAAHCANAGLQVILFDLPAPAGPPDTVVEKAIAGLAKLDPAPLASRALAAAITPANYASDLAR
LGECELVIEAIAEKMAWKLDLYAKVAPHLAPGAVFASNTSGLSIARLAEGLPAALRPRFCGVHFFNPPRYMALVELIPAP
DTDPALLDALEGWLTTRLGKRIVRARDTPNFIANRIGVFSVLAVMHHTTRLGLAFDEVDAITGPRIGRPKSATYRTADLV
GLDTLAHVVGTMQDGLPDDPWHGHFALPGWLDTLIANGALGQKTQAGIYRKEGRQILVFEPAQLDYRAAAGEVAVEVAEI
LALRDPAEKLAGLAACAHPQAQLLWSSFRDVFHYCAYHLEHIADNARDVDSAMRWGFGWAQGPFETWQAAGWAEVAAAIR
EDIAAGRAMSDAPLPDWVFERDGVHAAGGSWSPAAAALQPRPALPVYGRQLQAERLVGEAPPERGETLWECGERGDGVRL
WRLPALDAGIGVLSFKSKMHTVGGAVLEGVLEAVARAQRDLDGLVLWQPAPFSVGANLQQVGEACSAGEFARLEQTVARF
QQAALALRHAQVPVVAAVEGMALAGGCEFLMHCAHRVLALESYVGLVEAGVGLIPAGGGSKQFALQAHRLAQRAAGGDVF
PFIQRSFETIAKATVAKSAHEAVQLGFAAPGDDIVLHAQEVLYVALRRARALAEAGWHPPLPERAVVVAGRNGIATCELM
LVNMAEGGFISAHDYKVAKAAATALCGGEVDTNARVSEQWILDVERALFVELLQTEATQQRIAHMLRTGKPLRN

Sequences:

>Translated_794_residues
MLIRKVAVLGAGVMGAQIAAHCANAGLQVILFDLPAPAGPPDTVVEKAIAGLAKLDPAPLASRALAAAITPANYASDLAR
LGECELVIEAIAEKMAWKLDLYAKVAPHLAPGAVFASNTSGLSIARLAEGLPAALRPRFCGVHFFNPPRYMALVELIPAP
DTDPALLDALEGWLTTRLGKRIVRARDTPNFIANRIGVFSVLAVMHHTTRLGLAFDEVDAITGPRIGRPKSATYRTADLV
GLDTLAHVVGTMQDGLPDDPWHGHFALPGWLDTLIANGALGQKTQAGIYRKEGRQILVFEPAQLDYRAAAGEVAVEVAEI
LALRDPAEKLAGLAACAHPQAQLLWSSFRDVFHYCAYHLEHIADNARDVDSAMRWGFGWAQGPFETWQAAGWAEVAAAIR
EDIAAGRAMSDAPLPDWVFERDGVHAAGGSWSPAAAALQPRPALPVYGRQLQAERLVGEAPPERGETLWECGERGDGVRL
WRLPALDAGIGVLSFKSKMHTVGGAVLEGVLEAVARAQRDLDGLVLWQPAPFSVGANLQQVGEACSAGEFARLEQTVARF
QQAALALRHAQVPVVAAVEGMALAGGCEFLMHCAHRVLALESYVGLVEAGVGLIPAGGGSKQFALQAHRLAQRAAGGDVF
PFIQRSFETIAKATVAKSAHEAVQLGFAAPGDDIVLHAQEVLYVALRRARALAEAGWHPPLPERAVVVAGRNGIATCELM
LVNMAEGGFISAHDYKVAKAAATALCGGEVDTNARVSEQWILDVERALFVELLQTEATQQRIAHMLRTGKPLRN
>Mature_794_residues
MLIRKVAVLGAGVMGAQIAAHCANAGLQVILFDLPAPAGPPDTVVEKAIAGLAKLDPAPLASRALAAAITPANYASDLAR
LGECELVIEAIAEKMAWKLDLYAKVAPHLAPGAVFASNTSGLSIARLAEGLPAALRPRFCGVHFFNPPRYMALVELIPAP
DTDPALLDALEGWLTTRLGKRIVRARDTPNFIANRIGVFSVLAVMHHTTRLGLAFDEVDAITGPRIGRPKSATYRTADLV
GLDTLAHVVGTMQDGLPDDPWHGHFALPGWLDTLIANGALGQKTQAGIYRKEGRQILVFEPAQLDYRAAAGEVAVEVAEI
LALRDPAEKLAGLAACAHPQAQLLWSSFRDVFHYCAYHLEHIADNARDVDSAMRWGFGWAQGPFETWQAAGWAEVAAAIR
EDIAAGRAMSDAPLPDWVFERDGVHAAGGSWSPAAAALQPRPALPVYGRQLQAERLVGEAPPERGETLWECGERGDGVRL
WRLPALDAGIGVLSFKSKMHTVGGAVLEGVLEAVARAQRDLDGLVLWQPAPFSVGANLQQVGEACSAGEFARLEQTVARF
QQAALALRHAQVPVVAAVEGMALAGGCEFLMHCAHRVLALESYVGLVEAGVGLIPAGGGSKQFALQAHRLAQRAAGGDVF
PFIQRSFETIAKATVAKSAHEAVQLGFAAPGDDIVLHAQEVLYVALRRARALAEAGWHPPLPERAVVVAGRNGIATCELM
LVNMAEGGFISAHDYKVAKAAATALCGGEVDTNARVSEQWILDVERALFVELLQTEATQQRIAHMLRTGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=299, Percent_Identity=30.1003344481605, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI296179427, Length=316, Percent_Identity=29.4303797468354, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI20127408, Length=292, Percent_Identity=27.7397260273973, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI261878539, Length=298, Percent_Identity=26.510067114094, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI68989263, Length=298, Percent_Identity=26.510067114094, Blast_Score=71, Evalue=4e-12,
Organism=Escherichia coli, GI1787661, Length=455, Percent_Identity=26.8131868131868, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1790281, Length=227, Percent_Identity=30.3964757709251, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788682, Length=327, Percent_Identity=25.9938837920489, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17549919, Length=305, Percent_Identity=31.1475409836066, Blast_Score=115, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17553560, Length=300, Percent_Identity=27.6666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17563036, Length=300, Percent_Identity=30, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17508953, Length=293, Percent_Identity=29.3515358361775, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25144276, Length=293, Percent_Identity=29.3515358361775, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508951, Length=293, Percent_Identity=29.3515358361775, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=406, Percent_Identity=25.8620689655172, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985923, Length=419, Percent_Identity=23.3890214797136, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24583077, Length=299, Percent_Identity=25.752508361204, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583079, Length=299, Percent_Identity=25.752508361204, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19921000, Length=299, Percent_Identity=25.752508361204, Blast_Score=78, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 84526; Mature: 84526

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRKVAVLGAGVMGAQIAAHCANAGLQVILFDLPAPAGPPDTVVEKAIAGLAKLDPAPL
CCHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCH
ASRALAAAITPANYASDLARLGECELVIEAIAEKMAWKLDLYAKVAPHLAPGAVFASNTS
HHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
GLSIARLAEGLPAALRPRFCGVHFFNPPRYMALVELIPAPDTDPALLDALEGWLTTRLGK
CCHHHHHHCCCCHHHCCCCCCEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
RIVRARDTPNFIANRIGVFSVLAVMHHTTRLGLAFDEVDAITGPRIGRPKSATYRTADLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEEHHHHH
GLDTLAHVVGTMQDGLPDDPWHGHFALPGWLDTLIANGALGQKTQAGIYRKEGRQILVFE
HHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHCCCCCCCHHCCCHHHCCCEEEEEC
PAQLDYRAAAGEVAVEVAEILALRDPAEKLAGLAACAHPQAQLLWSSFRDVFHYCAYHLE
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HIADNARDVDSAMRWGFGWAQGPFETWQAAGWAEVAAAIREDIAAGRAMSDAPLPDWVFE
HHHCCHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHC
RDGVHAAGGSWSPAAAALQPRPALPVYGRQLQAERLVGEAPPERGETLWECGERGDGVRL
CCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEE
WRLPALDAGIGVLSFKSKMHTVGGAVLEGVLEAVARAQRDLDGLVLWQPAPFSVGANLQQ
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHH
VGEACSAGEFARLEQTVARFQQAALALRHAQVPVVAAVEGMALAGGCEFLMHCAHRVLAL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESYVGLVEAGVGLIPAGGGSKQFALQAHRLAQRAAGGDVFPFIQRSFETIAKATVAKSAH
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EAVQLGFAAPGDDIVLHAQEVLYVALRRARALAEAGWHPPLPERAVVVAGRNGIATCELM
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEE
LVNMAEGGFISAHDYKVAKAAATALCGGEVDTNARVSEQWILDVERALFVELLQTEATQQ
EEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RIAHMLRTGKPLRN
HHHHHHHCCCCCCC
>Mature Secondary Structure
MLIRKVAVLGAGVMGAQIAAHCANAGLQVILFDLPAPAGPPDTVVEKAIAGLAKLDPAPL
CCHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCH
ASRALAAAITPANYASDLARLGECELVIEAIAEKMAWKLDLYAKVAPHLAPGAVFASNTS
HHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCC
GLSIARLAEGLPAALRPRFCGVHFFNPPRYMALVELIPAPDTDPALLDALEGWLTTRLGK
CCHHHHHHCCCCHHHCCCCCCEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
RIVRARDTPNFIANRIGVFSVLAVMHHTTRLGLAFDEVDAITGPRIGRPKSATYRTADLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCEEHHHHH
GLDTLAHVVGTMQDGLPDDPWHGHFALPGWLDTLIANGALGQKTQAGIYRKEGRQILVFE
HHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHCCCCCCCHHCCCHHHCCCEEEEEC
PAQLDYRAAAGEVAVEVAEILALRDPAEKLAGLAACAHPQAQLLWSSFRDVFHYCAYHLE
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HIADNARDVDSAMRWGFGWAQGPFETWQAAGWAEVAAAIREDIAAGRAMSDAPLPDWVFE
HHHCCHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHC
RDGVHAAGGSWSPAAAALQPRPALPVYGRQLQAERLVGEAPPERGETLWECGERGDGVRL
CCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEE
WRLPALDAGIGVLSFKSKMHTVGGAVLEGVLEAVARAQRDLDGLVLWQPAPFSVGANLQQ
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHH
VGEACSAGEFARLEQTVARFQQAALALRHAQVPVVAAVEGMALAGGCEFLMHCAHRVLAL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
ESYVGLVEAGVGLIPAGGGSKQFALQAHRLAQRAAGGDVFPFIQRSFETIAKATVAKSAH
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EAVQLGFAAPGDDIVLHAQEVLYVALRRARALAEAGWHPPLPERAVVVAGRNGIATCELM
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEE
LVNMAEGGFISAHDYKVAKAAATALCGGEVDTNARVSEQWILDVERALFVELLQTEATQQ
EEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RIAHMLRTGKPLRN
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]