Click here to switch to the map view.

The map label for this gene is fadL [H]

Identifier: 119896758

GI number: 119896758

Start: 502438

End: 503721

Strand: Direct

Name: fadL [H]

Synonym: azo0467

Alternate gene names: 119896758

Gene position: 502438-503721 (Clockwise)

Preceding gene: 119896757

Following gene: 119896759

Centisome position: 11.48

GC content: 70.64

Gene sequence:

>1284_bases
ATGCAAACCACGACCCTGACCCGGGTAGCGGCGGCGCTTGCGCTCGCCGCCGGCCCGGCGCCGGCCTTCGCCGCCGGCTT
CCAGCTGCTGGAGCAGAACGCCAGCGGCATCGCCAACGCCTACGCCGGCTCCGCCGCGGTGGCCGAGGACGCCAGCACCA
TCTTCTTCAACCCCGCCGGCATGACCGCGCTGCGCGAGCGCGAGCTGTCGGTCGGTCTCGCCGCGGTGCGTCCGCGCTTC
GAGTTCAGCGACCGCGGCTCCACCGCCACCGGCGCGCTCGGGGGGGACGGCGGCGACGCGGGGTCGTGGGCTTACCTGCC
CAACGCCTACGTGTCGTGGGCGCTGCGGCCGGATCTCTACGTGGGCGTCGGCCTCGGCGCGCCGTTCGGGCTGATCACCG
AATACGACGACAACTGGGTGGGCGCCGCGCACTCGGTCAGCTTCGACATCAAGACCTACAACATCAACCCGTCGATCGCG
TGGCGCATCAACGAGCGGGTGTCGGTGGGCGGCGGGCTGAGCTGGCAGCGGATGGAGGTGGAGTACGAACGCGTCGCCGC
GGTGCTGCCGGCGCCGCTGCCGCTGTCGAGTACGCGCGCGATCCTCGACGCCGATTCCGACGCCTGGGGCTGGAACGTGG
GCGCCTTGATCACGCTGTCGCCGGCGACGCGGCTGGGGCTGTCCTACCGCTCGGCGATCAAGCACACGCTGGAGGGCGAC
CTGAAGGTGAAGGGCGCCGCGGCCGGCCTGTCGCCGGCACTGAGCAGCGGCAAGGCCAAGGCCGACGTCGAACTGCCGGA
TACCTTCATCCTCAGCGCGGTGCACAGGCTGGACGAGCGCTGGGAACTGCTCGGCGACATCAGCTGGACCGGCTGGAGCA
AGATCGACAAGGTCGACATCGTGCGCGACTCCGGCCCCTTGAGCGGCGTCACCGTGCAGACGCTGGACACCGATTTCCGC
GACACCTGGCGGGTGGCGCTGGGCGCGGGCTACCGGCTCAACGCGGCGTGGAAGCTCAAGGCCGGGCTGGCGTGGGATCA
AAGTCCGGTAAAGGACAGGGCGCATCGTCTGGTTTCGCTGCCCGACAACGACCGCACCTGGTTCGCCGCGGGCGCGCAAT
GGATGCCGGGCGGCGGCGCGCGGGTGGATCTGGGCCTCGCCTACCTCTACGTGCCGAAGACCAAGATCGACAACGACCAG
GCGGCGCTCGGCCGCGGCCGCGTCACCGGCGAGTACGATTCCAGCGTGTGGATACTGGGCGCGCAGTACTCGGTGGCGTT
CTAG

Upstream 100 bases:

>100_bases
TGGCGGGTGCCCCGGCACGGGCACCTGGCTTGCTGACCGACCGGGGGGCACACCCCGGTGTGCCGGAGCGGCGGGGGCCG
CACAGGAGGAGACGATACCG

Downstream 100 bases:

>100_bases
CGGATCGCGGCACGCCGCCGCACAGCAGGGGGGATGACGGTGAGCAAGATGCTGATACGCAAGGTGGCGGTGCTCGGCGC
CGGCGTCATGGGGGCGCAGA

Product: long-chain fatty acid ABC transporter

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MQTTTLTRVAAALALAAGPAPAFAAGFQLLEQNASGIANAYAGSAAVAEDASTIFFNPAGMTALRERELSVGLAAVRPRF
EFSDRGSTATGALGGDGGDAGSWAYLPNAYVSWALRPDLYVGVGLGAPFGLITEYDDNWVGAAHSVSFDIKTYNINPSIA
WRINERVSVGGGLSWQRMEVEYERVAAVLPAPLPLSSTRAILDADSDAWGWNVGALITLSPATRLGLSYRSAIKHTLEGD
LKVKGAAAGLSPALSSGKAKADVELPDTFILSAVHRLDERWELLGDISWTGWSKIDKVDIVRDSGPLSGVTVQTLDTDFR
DTWRVALGAGYRLNAAWKLKAGLAWDQSPVKDRAHRLVSLPDNDRTWFAAGAQWMPGGGARVDLGLAYLYVPKTKIDNDQ
AALGRGRVTGEYDSSVWILGAQYSVAF

Sequences:

>Translated_427_residues
MQTTTLTRVAAALALAAGPAPAFAAGFQLLEQNASGIANAYAGSAAVAEDASTIFFNPAGMTALRERELSVGLAAVRPRF
EFSDRGSTATGALGGDGGDAGSWAYLPNAYVSWALRPDLYVGVGLGAPFGLITEYDDNWVGAAHSVSFDIKTYNINPSIA
WRINERVSVGGGLSWQRMEVEYERVAAVLPAPLPLSSTRAILDADSDAWGWNVGALITLSPATRLGLSYRSAIKHTLEGD
LKVKGAAAGLSPALSSGKAKADVELPDTFILSAVHRLDERWELLGDISWTGWSKIDKVDIVRDSGPLSGVTVQTLDTDFR
DTWRVALGAGYRLNAAWKLKAGLAWDQSPVKDRAHRLVSLPDNDRTWFAAGAQWMPGGGARVDLGLAYLYVPKTKIDNDQ
AALGRGRVTGEYDSSVWILGAQYSVAF
>Mature_427_residues
MQTTTLTRVAAALALAAGPAPAFAAGFQLLEQNASGIANAYAGSAAVAEDASTIFFNPAGMTALRERELSVGLAAVRPRF
EFSDRGSTATGALGGDGGDAGSWAYLPNAYVSWALRPDLYVGVGLGAPFGLITEYDDNWVGAAHSVSFDIKTYNINPSIA
WRINERVSVGGGLSWQRMEVEYERVAAVLPAPLPLSSTRAILDADSDAWGWNVGALITLSPATRLGLSYRSAIKHTLEGD
LKVKGAAAGLSPALSSGKAKADVELPDTFILSAVHRLDERWELLGDISWTGWSKIDKVDIVRDSGPLSGVTVQTLDTDFR
DTWRVALGAGYRLNAAWKLKAGLAWDQSPVKDRAHRLVSLPDNDRTWFAAGAQWMPGGGARVDLGLAYLYVPKTKIDNDQ
AALGRGRVTGEYDSSVWILGAQYSVAF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=460, Percent_Identity=28.2608695652174, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 45490; Mature: 45490

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTTLTRVAAALALAAGPAPAFAAGFQLLEQNASGIANAYAGSAAVAEDASTIFFNPAG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCEEEECCCC
MTALRERELSVGLAAVRPRFEFSDRGSTATGALGGDGGDAGSWAYLPNAYVSWALRPDLY
CHHHHHHHHHCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCEEEEEECCCEE
VGVGLGAPFGLITEYDDNWVGAAHSVSFDIKTYNINPSIAWRINERVSVGGGLSWQRMEV
EEECCCCCCCEEEECCCCCCCCEEEEEEEEEEEECCCEEEEEEECEEEECCCCCEEEEEE
EYERVAAVLPAPLPLSSTRAILDADSDAWGWNVGALITLSPATRLGLSYRSAIKHTLEGD
EHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCHHHHCHHHHHHHHHHHCCC
LKVKGAAAGLSPALSSGKAKADVELPDTFILSAVHRLDERWELLGDISWTGWSKIDKVDI
EEEEEECCCCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
VRDSGPLSGVTVQTLDTDFRDTWRVALGAGYRLNAAWKLKAGLAWDQSPVKDRAHRLVSL
EECCCCCCCEEEEEECCCCHHHEEEEECCCEEECEEEEEECCCCCCCCCHHHHHHEEEEC
PDNDRTWFAAGAQWMPGGGARVDLGLAYLYVPKTKIDNDQAALGRGRVTGEYDSSVWILG
CCCCCEEEEECCEECCCCCCEEEEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCEEEEEE
AQYSVAF
EEEEECC
>Mature Secondary Structure
MQTTTLTRVAAALALAAGPAPAFAAGFQLLEQNASGIANAYAGSAAVAEDASTIFFNPAG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCEEEECCCC
MTALRERELSVGLAAVRPRFEFSDRGSTATGALGGDGGDAGSWAYLPNAYVSWALRPDLY
CHHHHHHHHHCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCEEEEEECCCEE
VGVGLGAPFGLITEYDDNWVGAAHSVSFDIKTYNINPSIAWRINERVSVGGGLSWQRMEV
EEECCCCCCCEEEECCCCCCCCEEEEEEEEEEEECCCEEEEEEECEEEECCCCCEEEEEE
EYERVAAVLPAPLPLSSTRAILDADSDAWGWNVGALITLSPATRLGLSYRSAIKHTLEGD
EHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCHHHHCHHHHHHHHHHHCCC
LKVKGAAAGLSPALSSGKAKADVELPDTFILSAVHRLDERWELLGDISWTGWSKIDKVDI
EEEEEECCCCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
VRDSGPLSGVTVQTLDTDFRDTWRVALGAGYRLNAAWKLKAGLAWDQSPVKDRAHRLVSL
EECCCCCCCEEEEEECCCCHHHEEEEECCCEEECEEEEEECCCCCCCCCHHHHHHEEEEC
PDNDRTWFAAGAQWMPGGGARVDLGLAYLYVPKTKIDNDQAALGRGRVTGEYDSSVWILG
CCCCCEEEEECCEECCCCCCEEEEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCEEEEEE
AQYSVAF
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]