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The map label for this gene is paaG1 [H]

Identifier: 119896591

GI number: 119896591

Start: 324719

End: 325522

Strand: Direct

Name: paaG1 [H]

Synonym: azo0300

Alternate gene names: 119896591

Gene position: 324719-325522 (Clockwise)

Preceding gene: 119896586

Following gene: 119896592

Centisome position: 7.42

GC content: 68.91

Gene sequence:

>804_bases
ATGAGCAGCTTCGAAACCATCCGCTACGAGGTCGCCGCCGGCGTCGCCACGCTGACCTTGAACCGCCCGGACCGCCTCAA
CAGCTTCAACGACCAGATGCACCGCGAAGTGCGCGAAGCGCTCGCCCAGGTGCAGGCCGGTCGCGCCGACGGTTCGGTGC
GGGTGCTGGTGATCGCGGCCGCCGGCCGCGGCTTCTGCGCCGGGCAGGATCTGTCCGACCGGAACGTGTCGGCCGGTGCC
GAAGCGCCCGACCTCGGCGCCTCGATCGAGAAGAACTACAAGCCGCTGGTGACGACGCTGCGCAACCTCGACCTGCCGGT
GATCGCAGCGGTGAATGGCGTGGCCGCCGGCGCCGGCGCCAACCTGGCGCTCGCCTGCGACCTGGTGTTCGCGGCGCGCT
CGGCGAGCTTCATCCAGTCCTTCGCCAAGCTCGGCCTGGTTCCCGACACCGGCGGCTCCTGGATCCTGCCGCGCCTGCTC
GGTCCGGCCCGCGCGCTGGGGCTGGCGCTGCTCGGCGACAAGCTGCCGGCCGAACAGGCCGAACAATGGGGCCTGATCTG
GAAATGCGTGGATGACGACGCCCTGCAGGCCACCGTGCAGCAGGTCGCGGCCACGCTCGCCAACGGTCCCACCTTCGGCT
ACGCCCAGACCAAGAAGGCGATCTGGGCCAGCACCACCAACGATTTCGACACCCAACTCGACCTCGAGCGCGATGCCATG
CGGGCCTGCGGCCGCTCGCATGACTACCGCGAAGGCGTGGCCGCCTTCATGGAAAAACGCGCTCCTCAATTCAAGGGGAA
TTAA

Upstream 100 bases:

>100_bases
CCTTCGAATCCCAAAAGACGCTCGAACCAAGGACAAGCAGCGCCCGGTCGGTTCCCGTCGCCCATCGCGGGACGGCCGGC
GTGCCAGCAGGAGGAGACAG

Downstream 100 bases:

>100_bases
GGCGTGACTGCAGCAGACAAGGCGCTCGACAAGCAGGTGAAGGTGCTGGTGATCGGTGCCGGCGCGATGGGCAGCGGCAT
TGCCCACGTGGCGGCGCTGG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSSFETIRYEVAAGVATLTLNRPDRLNSFNDQMHREVREALAQVQAGRADGSVRVLVIAAAGRGFCAGQDLSDRNVSAGA
EAPDLGASIEKNYKPLVTTLRNLDLPVIAAVNGVAAGAGANLALACDLVFAARSASFIQSFAKLGLVPDTGGSWILPRLL
GPARALGLALLGDKLPAEQAEQWGLIWKCVDDDALQATVQQVAATLANGPTFGYAQTKKAIWASTTNDFDTQLDLERDAM
RACGRSHDYREGVAAFMEKRAPQFKGN

Sequences:

>Translated_267_residues
MSSFETIRYEVAAGVATLTLNRPDRLNSFNDQMHREVREALAQVQAGRADGSVRVLVIAAAGRGFCAGQDLSDRNVSAGA
EAPDLGASIEKNYKPLVTTLRNLDLPVIAAVNGVAAGAGANLALACDLVFAARSASFIQSFAKLGLVPDTGGSWILPRLL
GPARALGLALLGDKLPAEQAEQWGLIWKCVDDDALQATVQQVAATLANGPTFGYAQTKKAIWASTTNDFDTQLDLERDAM
RACGRSHDYREGVAAFMEKRAPQFKGN
>Mature_266_residues
SSFETIRYEVAAGVATLTLNRPDRLNSFNDQMHREVREALAQVQAGRADGSVRVLVIAAAGRGFCAGQDLSDRNVSAGAE
APDLGASIEKNYKPLVTTLRNLDLPVIAAVNGVAAGAGANLALACDLVFAARSASFIQSFAKLGLVPDTGGSWILPRLLG
PARALGLALLGDKLPAEQAEQWGLIWKCVDDDALQATVQQVAATLANGPTFGYAQTKKAIWASTTNDFDTQLDLERDAMR
ACGRSHDYREGVAAFMEKRAPQFKGN

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=30.952380952381, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=27.6, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI45643119, Length=223, Percent_Identity=27.8026905829596, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI260275230, Length=223, Percent_Identity=27.8026905829596, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI260274832, Length=223, Percent_Identity=27.8026905829596, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4502327, Length=260, Percent_Identity=31.9230769230769, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI70995211, Length=199, Percent_Identity=30.6532663316583, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI4757968, Length=173, Percent_Identity=31.7919075144509, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI49355787, Length=173, Percent_Identity=31.7919075144509, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116235487, Length=185, Percent_Identity=27.5675675675676, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221307494, Length=168, Percent_Identity=32.7380952380952, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI25453481, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51538573, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4757966, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51538581, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=215, Percent_Identity=25.1162790697674, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221136756, Length=168, Percent_Identity=32.7380952380952, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI221136753, Length=168, Percent_Identity=32.7380952380952, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI37594469, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI37594471, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI68989263, Length=187, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI150378541, Length=259, Percent_Identity=28.957528957529, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157694516, Length=230, Percent_Identity=24.3478260869565, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI213417737, Length=230, Percent_Identity=24.3478260869565, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787660, Length=264, Percent_Identity=60.2272727272727, Blast_Score=291, Evalue=2e-80,
Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=34.1269841269841, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI221142681, Length=267, Percent_Identity=33.7078651685393, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788597, Length=267, Percent_Identity=30.3370786516854, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788682, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082183, Length=269, Percent_Identity=22.6765799256506, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=32.6848249027237, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=30.2788844621514, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17535521, Length=252, Percent_Identity=28.1746031746032, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=28.4444444444444, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=237, Percent_Identity=29.535864978903, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=25, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=171, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=215, Percent_Identity=27.906976744186, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=267, Percent_Identity=24.7191011235955, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20129971, Length=266, Percent_Identity=29.6992481203008, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24653477, Length=266, Percent_Identity=29.6992481203008, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=33.0769230769231, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24654903, Length=205, Percent_Identity=28.2926829268293, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19922422, Length=260, Percent_Identity=25.3846153846154, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=28.515625, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357171, Length=222, Percent_Identity=25.6756756756757, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571730, Length=158, Percent_Identity=30.379746835443, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571729, Length=158, Percent_Identity=30.379746835443, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28376; Mature: 28245

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFETIRYEVAAGVATLTLNRPDRLNSFNDQMHREVREALAQVQAGRADGSVRVLVIAA
CCCHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
AGRGFCAGQDLSDRNVSAGAEAPDLGASIEKNYKPLVTTLRNLDLPVIAAVNGVAAGAGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCHHHHHCCHHCCCCC
NLALACDLVFAARSASFIQSFAKLGLVPDTGGSWILPRLLGPARALGLALLGDKLPAEQA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCHHHHHHHHHHCCCCCHHHH
EQWGLIWKCVDDDALQATVQQVAATLANGPTFGYAQTKKAIWASTTNDFDTQLDLERDAM
HHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCCCCCCHHHHH
RACGRSHDYREGVAAFMEKRAPQFKGN
HHHCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSFETIRYEVAAGVATLTLNRPDRLNSFNDQMHREVREALAQVQAGRADGSVRVLVIAA
CCHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
AGRGFCAGQDLSDRNVSAGAEAPDLGASIEKNYKPLVTTLRNLDLPVIAAVNGVAAGAGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCHHHHHCCHHCCCCC
NLALACDLVFAARSASFIQSFAKLGLVPDTGGSWILPRLLGPARALGLALLGDKLPAEQA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCHHHHHHHHHHCCCCCHHHH
EQWGLIWKCVDDDALQATVQQVAATLANGPTFGYAQTKKAIWASTTNDFDTQLDLERDAM
HHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCCCCCCHHHHH
RACGRSHDYREGVAAFMEKRAPQFKGN
HHHCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]