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The map label for this gene is mreB [H]

Identifier: 119896466

GI number: 119896466

Start: 190256

End: 191299

Strand: Direct

Name: mreB [H]

Synonym: azo0174

Alternate gene names: 119896466

Gene position: 190256-191299 (Clockwise)

Preceding gene: 119896457

Following gene: 119896467

Centisome position: 4.35

GC content: 65.42

Gene sequence:

>1044_bases
ATGTTTGGTTTTCTGCGCTCTTATTTTTCCAACGATCTCGCCATCGACCTTGGCACTGCGAACACGCTGATCTACGTGCG
CGGCAAGGGCATCGTGCTCGACGAACCCTCCGTGGTCGCCATCCGCACCGAGGGCGGTCCCAACGCCAAGCGCACCATCC
AGGCGGTGGGCCACGCGGCCAAGCAGATGCTTGGCAAGACCCCGGGCAACATCACCGCGATCCGCCCGATGAAGGACGGT
GTCATCGCCGATTTCGTCGTCACCGAGCAGATGATCAAGCAGTTCATCAAGAAGGTGCACGATTCCCGCCTGCTGTCGCC
CAGCCCGCGCATCATCATCTGCGTGCCCTGCGGCTCCACCCAGGTCGAACGCCGCGCGATCCGCGACGCGGCCCTCGCCG
CGGGCGCCTCGCAGGTGTATCTGATCGAGGAACCGATGGCCGCGGCGATCGGTGCCGGCCTGCCGGTGTCGGATGCCACC
GGCTCCATGGTGGTCGATATCGGCGGGGGCACCACCGAAGTCGGCGTGATCTCGCTCGGCGGCATGGTCTATGCCGGCAG
CGTGCGCGTCGGCGGCGACAAGTTCGACGATGCCATCGTCAATTACATCCGCCGCAACTACGGCATGCTGATCGGCGACA
CCACCGCCGAGAACATCAAGAAGAACATCGGCTCGGCCTTCCCCGGCTCCGAAGTGCGCGAAATGGAAGTCAAGGGCCGC
AACCTGGCCGAAGGCATCCCGCGCAGCTTCACCATCTCGTCCAACGAAATCCTGGAAGCGCTCACCGAACCGCTCAACCA
GATCGTCTCCGCGGTCAAGATCGCGCTGGAACAGACCCCGCCCGAACTCGGCGCCGATATCGCCGACCGCGGCATGGTGC
TGACCGGCGGCGGTGCGCTGCTGCGCGACCTCGACCGCCTGCTGATGGAGGAGACCGGCCTGCCGGTGATCGTGGCCGAG
GAGCCGCTGACCTGCGTGGCGCGCGGCTGCGGCCTAGCGCTCGACAAGATGGACAAGCTCGGCTCCATCTTCACGTCGGA
CTGA

Upstream 100 bases:

>100_bases
CTGAATCGACAAAGGTTTGTAGGTTATCATATCCGCCTTTGGCCTGGCTCCGGGCCCGCCCCTCCGCGGCGCTTCTTCCC
CACCGGTTTCGGAATCCCTC

Downstream 100 bases:

>100_bases
TCCGCGCAGTCACGGCGTTTTTCCTGCTGATCCGGAAATCCCAGGATGTCCCTCGCCGGCCATCAGCCGCCTCCTATTTT
CCGGCGCGGCCTCGCACCGC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFGFLRSYFSNDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRTEGGPNAKRTIQAVGHAAKQMLGKTPGNITAIRPMKDG
VIADFVVTEQMIKQFIKKVHDSRLLSPSPRIIICVPCGSTQVERRAIRDAALAAGASQVYLIEEPMAAAIGAGLPVSDAT
GSMVVDIGGGTTEVGVISLGGMVYAGSVRVGGDKFDDAIVNYIRRNYGMLIGDTTAENIKKNIGSAFPGSEVREMEVKGR
NLAEGIPRSFTISSNEILEALTEPLNQIVSAVKIALEQTPPELGADIADRGMVLTGGGALLRDLDRLLMEETGLPVIVAE
EPLTCVARGCGLALDKMDKLGSIFTSD

Sequences:

>Translated_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRTEGGPNAKRTIQAVGHAAKQMLGKTPGNITAIRPMKDG
VIADFVVTEQMIKQFIKKVHDSRLLSPSPRIIICVPCGSTQVERRAIRDAALAAGASQVYLIEEPMAAAIGAGLPVSDAT
GSMVVDIGGGTTEVGVISLGGMVYAGSVRVGGDKFDDAIVNYIRRNYGMLIGDTTAENIKKNIGSAFPGSEVREMEVKGR
NLAEGIPRSFTISSNEILEALTEPLNQIVSAVKIALEQTPPELGADIADRGMVLTGGGALLRDLDRLLMEETGLPVIVAE
EPLTCVARGCGLALDKMDKLGSIFTSD
>Mature_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRTEGGPNAKRTIQAVGHAAKQMLGKTPGNITAIRPMKDG
VIADFVVTEQMIKQFIKKVHDSRLLSPSPRIIICVPCGSTQVERRAIRDAALAAGASQVYLIEEPMAAAIGAGLPVSDAT
GSMVVDIGGGTTEVGVISLGGMVYAGSVRVGGDKFDDAIVNYIRRNYGMLIGDTTAENIKKNIGSAFPGSEVREMEVKGR
NLAEGIPRSFTISSNEILEALTEPLNQIVSAVKIALEQTPPELGADIADRGMVLTGGGALLRDLDRLLMEETGLPVIVAE
EPLTCVARGCGLALDKMDKLGSIFTSD

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=240, Percent_Identity=27.9166666666667, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI167466173, Length=243, Percent_Identity=26.7489711934156, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI194248072, Length=243, Percent_Identity=26.7489711934156, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082236, Length=349, Percent_Identity=71.3467048710602, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1786870, Length=214, Percent_Identity=29.4392523364486, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788875, Length=248, Percent_Identity=27.4193548387097, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17534015, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17534013, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507981, Length=136, Percent_Identity=28.6764705882353, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324120, Length=240, Percent_Identity=23.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319972, Length=240, Percent_Identity=23.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323401, Length=265, Percent_Identity=26.0377358490566, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322426, Length=237, Percent_Identity=25.3164556962025, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320950, Length=209, Percent_Identity=25.8373205741627, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36660; Mature: 36660

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRTEGGPNAKRTIQAVGHAA
CCHHHHHHCCCCEEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKTPGNITAIRPMKDGVIADFVVTEQMIKQFIKKVHDSRLLSPSPRIIICVPCGST
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
QVERRAIRDAALAAGASQVYLIEEPMAAAIGAGLPVSDATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYAGSVRVGGDKFDDAIVNYIRRNYGMLIGDTTAENIKKNIGSAFPGSEVREMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCCCHHHHHHCCC
NLAEGIPRSFTISSNEILEALTEPLNQIVSAVKIALEQTPPELGADIADRGMVLTGGGAL
CHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHCCEEEECCCHH
LRDLDRLLMEETGLPVIVAEEPLTCVARGCGLALDKMDKLGSIFTSD
HHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRTEGGPNAKRTIQAVGHAA
CCHHHHHHCCCCEEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKTPGNITAIRPMKDGVIADFVVTEQMIKQFIKKVHDSRLLSPSPRIIICVPCGST
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCH
QVERRAIRDAALAAGASQVYLIEEPMAAAIGAGLPVSDATGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYAGSVRVGGDKFDDAIVNYIRRNYGMLIGDTTAENIKKNIGSAFPGSEVREMEVKGR
CEEEECEEEECCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCCCHHHHHHCCC
NLAEGIPRSFTISSNEILEALTEPLNQIVSAVKIALEQTPPELGADIADRGMVLTGGGAL
CHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHCCEEEECCCHH
LRDLDRLLMEETGLPVIVAEEPLTCVARGCGLALDKMDKLGSIFTSD
HHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]