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The map label for this gene is atpA [H]

Identifier: 119896449

GI number: 119896449

Start: 174303

End: 175841

Strand: Direct

Name: atpA [H]

Synonym: azo0157

Alternate gene names: 119896449

Gene position: 174303-175841 (Clockwise)

Preceding gene: 119896448

Following gene: 119896450

Centisome position: 3.98

GC content: 63.81

Gene sequence:

>1539_bases
ATGCAACTCAACCCCTCTGAAATCAGTGATCTGATTAAGAGCCGGATTCAGAACCTGCAGCTCGCCGCCACGTCGCGCAA
CGAGGGTACGGTGGTTTCCGTCACCGACGGTATCACCCGCATCCACGGCCTCACCGACGTCATGCAGGGCGAAATGCTGG
AGTTCCCCGGCAACACCTTCGGCCTCGCGCTCAACCTCGAGCGTGATTCCGTCGGCGCGGTCGTGCTCGGCGAATACGAG
CACATCACCGAAGGCGACACCGTCAAGGCCACTGGCCGCATTCTCGAAGTGCCCGTCGGCCCCGAGCTGATCGGCCGCGT
CGTCAATGCGCTGGGTCAGCCGATCGACGGCAAGGGCCCGATCAATGCCAAGCTCACCGACAAGATCGAAAAGGTCGCGC
CGGGCGTCATCGCCCGCCAGTCCGTTTCGCAGCCGGTGCAGACCGGTCTGAAGTCGGTCGACTCCATGGTGCCGATCGGC
CGTGGCCAGCGCGAGCTGATCATCGGCGACCGCCAGACCGGCAAGACGGCTGTCGCGGTTGATGCCATCATCAACCAGAA
AGGCCAGAACATGTTCTGCGTCTACGTTGCGATCGGCCAGAAGGCTTCGACCATCGCCAACGTCGTGCGCAAGCTGGAAG
AAAACGGCGCGATGGAATACACCATCGTCGTCGCCGCGACCGCTTCCGAATCCGCCGCCATGCAGTACCTGTCGGCGTAC
GCCGGCTGCACCATGGGCGAGTACTTCCGCGACCGTGGTCAAGACGCGCTGATCGTCTATGACGATCTGACCAAGCAAGC
CTGGGCCTACCGTCAGGTCTCCCTGCTGCTGCGCCGTCCGCCGGGCCGCGAAGCCTACCCGGGCGACGTGTTCTACCTGC
ACTCCCGCCTGCTCGAGCGCGCCGCCCGCGTGAACGCCGACTACGTCGAGAAGTTCACCAACGGCGAAGTCAAGGGCAAG
ACCGGTTCGCTGACCGCCCTGCCGGTCATCGAAACCCAGGCCGGCGACGTGTCCGCGTTCGTGCCGACCAACGTGATCTC
GATTACCGACGGTCAGATCTTCCTGGAAACCGACCTCTTCAACGCTGGTATCCGTCCCGCGATCAACGCCGGTATCTCGG
TGTCCCGCGTCGGTGGTGCCGCGCAGACCAAGGTCGTCAAGAAGCTCTCCGGCGGTATCCGTACCGACCTCGCGCAGTAC
CGCGAACTCGCCGCGTTCGCCCAGTTCGCCTCCGACCTGGACGATGCAACCCGCAAGCAGCTCGAGCGCGGCCGCCGCGT
TACCGAACTGATGAAGCAGCCGCAATACGCGCCGCTGTCGGTCGCCGAAATGGCCATCACCCTGTACGCGGTGAACAACG
GCTACTTCGACGACGTCGAAGTGGCTCGCGTGCTGGCCTTCGAATCCGGTCTGCAGCAGTTCGTCAAGGCCAAGGCGCCT
GAACTCGTCGCCAAGATCACCGACACCAAGGAACTCGACGCCGACGGCGAGAAGACCCTGGTTGCCGCGATCGCCGAGTT
CAAGAAGAGCTGGGCCTAA

Upstream 100 bases:

>100_bases
GGGGTCCGCATCGCCGTCGGCGACGAAGTGATCGACGCCTCGGTCCGCGGCAAGCTCGCGAACATGGCCGCTGCGCTCAA
GAACTAGGAGTTATCGCAAA

Downstream 100 bases:

>100_bases
GGCCGCGGACGGAGACGGAATATGGCTAGCGGTAAGGAAATCCGTACCAAGATCAAGAGCGTGCAAAACACGCGAAAGAT
CACCAAGGCCATGGAAATGG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MQLNPSEISDLIKSRIQNLQLAATSRNEGTVVSVTDGITRIHGLTDVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYE
HITEGDTVKATGRILEVPVGPELIGRVVNALGQPIDGKGPINAKLTDKIEKVAPGVIARQSVSQPVQTGLKSVDSMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGQNMFCVYVAIGQKASTIANVVRKLEENGAMEYTIVVAATASESAAMQYLSAY
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKFTNGEVKGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELMKQPQYAPLSVAEMAITLYAVNNGYFDDVEVARVLAFESGLQQFVKAKAP
ELVAKITDTKELDADGEKTLVAAIAEFKKSWA

Sequences:

>Translated_512_residues
MQLNPSEISDLIKSRIQNLQLAATSRNEGTVVSVTDGITRIHGLTDVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYE
HITEGDTVKATGRILEVPVGPELIGRVVNALGQPIDGKGPINAKLTDKIEKVAPGVIARQSVSQPVQTGLKSVDSMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGQNMFCVYVAIGQKASTIANVVRKLEENGAMEYTIVVAATASESAAMQYLSAY
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKFTNGEVKGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELMKQPQYAPLSVAEMAITLYAVNNGYFDDVEVARVLAFESGLQQFVKAKAP
ELVAKITDTKELDADGEKTLVAAIAEFKKSWA
>Mature_512_residues
MQLNPSEISDLIKSRIQNLQLAATSRNEGTVVSVTDGITRIHGLTDVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYE
HITEGDTVKATGRILEVPVGPELIGRVVNALGQPIDGKGPINAKLTDKIEKVAPGVIARQSVSQPVQTGLKSVDSMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGQNMFCVYVAIGQKASTIANVVRKLEENGAMEYTIVVAATASESAAMQYLSAY
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEKFTNGEVKGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDDATRKQLERGRRVTELMKQPQYAPLSVAEMAITLYAVNNGYFDDVEVARVLAFESGLQQFVKAKAP
ELVAKITDTKELDADGEKTLVAAIAEFKKSWA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=56.078431372549, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=56.078431372549, Blast_Score=574, Evalue=1e-164,
Organism=Homo sapiens, GI32189394, Length=432, Percent_Identity=25.462962962963, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI19913428, Length=312, Percent_Identity=27.5641025641026, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913426, Length=318, Percent_Identity=27.0440251572327, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI19913424, Length=262, Percent_Identity=27.4809160305344, Blast_Score=80, Evalue=7e-15,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=70.5653021442495, Blast_Score=747, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=374, Percent_Identity=24.5989304812834, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=27.0462633451957, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=55.1456310679612, Blast_Score=564, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=55.1456310679612, Blast_Score=563, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.2621359223301, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25144756, Length=434, Percent_Identity=24.8847926267281, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=303, Percent_Identity=28.0528052805281, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=378, Percent_Identity=25.9259259259259, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=27.1653543307087, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=56, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=55.3816046966732, Blast_Score=569, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6322581, Length=397, Percent_Identity=26.9521410579345, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319603, Length=309, Percent_Identity=28.4789644012945, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=55.0583657587549, Blast_Score=569, Evalue=1e-162,
Organism=Drosophila melanogaster, GI281361666, Length=305, Percent_Identity=27.5409836065574, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646341, Length=305, Percent_Identity=27.5409836065574, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136796, Length=305, Percent_Identity=27.5409836065574, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24638766, Length=388, Percent_Identity=25, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI28574560, Length=450, Percent_Identity=24, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=28.2352941176471, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=28.2352941176471, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=28.2352941176471, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129479, Length=250, Percent_Identity=28, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55289; Mature: 55289

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISDLIKSRIQNLQLAATSRNEGTVVSVTDGITRIHGLTDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCCEECCCCEE
GLALNLERDSVGAVVLGEYEHITEGDTVKATGRILEVPVGPELIGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEEECCHHCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKLTDKIEKVAPGVIARQSVSQPVQTGLKSVDSMVPIGRGQRELIIGDRQTGKTAVAV
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGQNMFCVYVAIGQKASTIANVVRKLEENGAMEYTIVVAATASESAAMQYLSAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNADYVEKFTNGEVKGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDDATRKQ
CCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELMKQPQYAPLSVAEMAITLYAVNNGYFDDVEVARVLAFESGLQQFVKAKAP
HHHCHHHHHHHHCCCCCCCHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCH
ELVAKITDTKELDADGEKTLVAAIAEFKKSWA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLNPSEISDLIKSRIQNLQLAATSRNEGTVVSVTDGITRIHGLTDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEECCCHHHHHHHHHHHCCCCEECCCCEE
GLALNLERDSVGAVVLGEYEHITEGDTVKATGRILEVPVGPELIGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEEECCHHCCCCCCEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKLTDKIEKVAPGVIARQSVSQPVQTGLKSVDSMVPIGRGQRELIIGDRQTGKTAVAV
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGQNMFCVYVAIGQKASTIANVVRKLEENGAMEYTIVVAATASESAAMQYLSAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNADYVEKFTNGEVKGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDDATRKQ
CCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELMKQPQYAPLSVAEMAITLYAVNNGYFDDVEVARVLAFESGLQQFVKAKAP
HHHCHHHHHHHHCCCCCCCHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCH
ELVAKITDTKELDADGEKTLVAAIAEFKKSWA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA