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The map label for this gene is atpB

Identifier: 119896445

GI number: 119896445

Start: 172088

End: 172936

Strand: Direct

Name: atpB

Synonym: azo0153

Alternate gene names: 119896445

Gene position: 172088-172936 (Clockwise)

Preceding gene: 119896444

Following gene: 119896446

Centisome position: 3.93

GC content: 61.13

Gene sequence:

>849_bases
ATGGCTACAGAGCACGCACCAACCGCATCAGAATACGTCGTCCACCACCTTACCCACCTCAACAGCACCGGTCATGCGCA
GACCAGCATCGTCGACTTCAGCGTCATCAACGTCGACTCGATGTTCTATTCGGTGCTGCTCGGGCTGCTGACGGTCTTCT
TGCTGTGGCTGGCCGCCCGCAAGGCAACCGCCGGTGTGCCGGGGCGCTTCCAGGGCTTTGTCGAACTGCTCGTTGAAATG
GTCGCAGACCAAGCCAAGGGCATCATCCACAGCGCCGAATCGCGCAAGTTCGTTGCTCCGCTCGCGCTCACCGTGTTCGT
CTGGATTTTCCTGATGAACGCGATGGACATGCTGCCGGTCGATCTGCTGCCGCGCATCTGGGAAGGCGTCTATGCCTCTG
CCGGGGGTGATCCGCATCACGCCTACATGCGTGTGGTGCCGACCGCCGACCTGTCGGCCACGCTGGGCATGTCCTGCGGC
GTGCTGCTGCTCTGCCTGTACTACAACGTCAAGATCAAGGGCGTCTCGGGCTGGGTGCACGAGCTCTTCACCGCGCCGTT
CGGCAGCCACCCGCTGCTCTACCCGATCAACTTCGCGATGCAGATCATCGAATTCGTCGCCAAGACCGTGTCCCACGGCA
TGCGACTGTTCGGCAACATGTACGCCGGCGAACTGATCTTCATCCTGATCGCGCTGCTCGGCTCCACCGCCACCGTGTTC
GGTTTCGTCGGCCACATCGTCGCGGGTTCCATCTGGGCCATCTTCCACATCCTGATCATCACCCTGCAGGCCTTCATCTT
CATGATGCTGACCCTGGTGTACATCGGCCAGGCGCACGAAGGTCACTAA

Upstream 100 bases:

>100_bases
TTCCGGCCTTGTATCCGGGCGTCCATTGGGGCGCGCTGCTGATCGGCCTGATTCTGGCGCTCAAGGCGAATTTGTTTGCA
TTCTTGGTAAGAAACTGACT

Downstream 100 bases:

>100_bases
GCTTTTTTCGCAGTACCCATTTTTAAACTCAATCATCTTTAACTAAGGAGTCGTCATGGAAAACGTTCTGGGTTTTGTTG
CGCTGGCTGCTGGTCTGATC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MATEHAPTASEYVVHHLTHLNSTGHAQTSIVDFSVINVDSMFYSVLLGLLTVFLLWLAARKATAGVPGRFQGFVELLVEM
VADQAKGIIHSAESRKFVAPLALTVFVWIFLMNAMDMLPVDLLPRIWEGVYASAGGDPHHAYMRVVPTADLSATLGMSCG
VLLLCLYYNVKIKGVSGWVHELFTAPFGSHPLLYPINFAMQIIEFVAKTVSHGMRLFGNMYAGELIFILIALLGSTATVF
GFVGHIVAGSIWAIFHILIITLQAFIFMMLTLVYIGQAHEGH

Sequences:

>Translated_282_residues
MATEHAPTASEYVVHHLTHLNSTGHAQTSIVDFSVINVDSMFYSVLLGLLTVFLLWLAARKATAGVPGRFQGFVELLVEM
VADQAKGIIHSAESRKFVAPLALTVFVWIFLMNAMDMLPVDLLPRIWEGVYASAGGDPHHAYMRVVPTADLSATLGMSCG
VLLLCLYYNVKIKGVSGWVHELFTAPFGSHPLLYPINFAMQIIEFVAKTVSHGMRLFGNMYAGELIFILIALLGSTATVF
GFVGHIVAGSIWAIFHILIITLQAFIFMMLTLVYIGQAHEGH
>Mature_281_residues
ATEHAPTASEYVVHHLTHLNSTGHAQTSIVDFSVINVDSMFYSVLLGLLTVFLLWLAARKATAGVPGRFQGFVELLVEMV
ADQAKGIIHSAESRKFVAPLALTVFVWIFLMNAMDMLPVDLLPRIWEGVYASAGGDPHHAYMRVVPTADLSATLGMSCGV
LLLCLYYNVKIKGVSGWVHELFTAPFGSHPLLYPINFAMQIIEFVAKTVSHGMRLFGNMYAGELIFILIALLGSTATVFG
FVGHIVAGSIWAIFHILIITLQAFIFMMLTLVYIGQAHEGH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=288, Percent_Identity=47.2222222222222, Blast_Score=224, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_AZOSB (A1K1R6)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_931658.1
- ProteinModelPortal:   A1K1R6
- SMR:   A1K1R6
- STRING:   A1K1R6
- GeneID:   4606242
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0153
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   AGELVFM
- PhylomeDB:   A1K1R6
- ProtClustDB:   PRK05815
- BioCyc:   ASP62928:AZO0153-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 30908; Mature: 30777

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x149ec6fc)-; HASH(0x192284d0)-; HASH(0x182395a4)-; HASH(0x19221818)-; HASH(0x1922506c)-; HASH(0x18488930)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEHAPTASEYVVHHLTHLNSTGHAQTSIVDFSVINVDSMFYSVLLGLLTVFLLWLAAR
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KATAGVPGRFQGFVELLVEMVADQAKGIIHSAESRKFVAPLALTVFVWIFLMNAMDMLPV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
DLLPRIWEGVYASAGGDPHHAYMRVVPTADLSATLGMSCGVLLLCLYYNVKIKGVSGWVH
HHHHHHHHHHHHCCCCCCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCEEECCHHHHH
ELFTAPFGSHPLLYPINFAMQIIEFVAKTVSHGMRLFGNMYAGELIFILIALLGSTATVF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GFVGHIVAGSIWAIFHILIITLQAFIFMMLTLVYIGQAHEGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
ATEHAPTASEYVVHHLTHLNSTGHAQTSIVDFSVINVDSMFYSVLLGLLTVFLLWLAAR
CCCCCCCHHHHHHHHHHHCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KATAGVPGRFQGFVELLVEMVADQAKGIIHSAESRKFVAPLALTVFVWIFLMNAMDMLPV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
DLLPRIWEGVYASAGGDPHHAYMRVVPTADLSATLGMSCGVLLLCLYYNVKIKGVSGWVH
HHHHHHHHHHHHCCCCCCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCEEECCHHHHH
ELFTAPFGSHPLLYPINFAMQIIEFVAKTVSHGMRLFGNMYAGELIFILIALLGSTATVF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GFVGHIVAGSIWAIFHILIITLQAFIFMMLTLVYIGQAHEGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA