Click here to switch to the map view.

The map label for this gene is aas [H]

Identifier: 119896442

GI number: 119896442

Start: 169028

End: 171166

Strand: Reverse

Name: aas [H]

Synonym: azo0150

Alternate gene names: 119896442

Gene position: 171166-169028 (Counterclockwise)

Preceding gene: 119896443

Following gene: 119896441

Centisome position: 3.91

GC content: 67.93

Gene sequence:

>2139_bases
ATGCCTGTGATCAGATTCGTGCTGCGCCTGCTGCTCGGCACTCTCTTCAGCGTTCGCGTGCGCGGCGACAACGCGTCGCT
CTCGGCGCGCCGTCTGCTCATCGTCGCCAATCACGAGTCCTTCCTCGACGGCCTTCTGCTGGGTCTGTTCCTGCCGGCGG
ACCCCGTGTTCGTGGTTCACACCGGCGTCACCCGCCGCTTCTGGTTCAGGCTCGCGTTGAGGCTGGTCGATCATCTTGCG
GTCGACCCGACCAACCCGATGGCGATGAAGCGCGTGATCCGGCTGCTGGAAGAAGGCCGCCCGGTGGTCATCTTCCCGGA
GGGGCGCATCACCGTCACCGGCAGCCTGATGAAGGTGTACGAGGGCCCCGCCTTCGTGGCCGCGAAGACCGGCGCGACCA
TCGTGCCGGTGCGCCTCGACGGCGCCGCCCGCAGCTACTTCTCGCGCGTTGCCGGCCGCCATCCCCGCCGCATGCTGCCG
CGCATCACATTGAGCATCCAGCCGCCGACCCGGATCGAGATGCCGGAAGCGCCCACCGCGAAGGCGCGCCGCCAGAAGGC
GGGCGAGGCGATGCGGCGCCTGATGCAGGAGATGCTGTTCGCCTCGCGGCCGTCACAGACGCTGTTCGACGCGCTGCTCG
ACACCGCGGCGCTGCACGGGCGGCAACGCGCCGTGGTGGAGGACGTCAAGCAGGTGGAATACAGCTACGGCGACCTGATC
AAGATGTCGCTCGCACTCGGTCGGCTCGGCAGCCGACTGGGCGGGCCGGGCGAGCGCATCGGCGTCCTGCTGCCCAATCT
GGCGCCCACGCTCGGACTGGTTTTCGGTCTCAATGCCTTCGGCCGCACGCCGGCGATGCTGAACTACACCGCTGGAACCG
AAGGGCTGCAGGCGGCCTGCACCGCGGCGTGCCTGCGCACGGTCATCACCTCACGTGCCTTCCTGGAGCAGGCCCGGCTT
ACGGAGCGCGTCACGGCGCTCGAAGGCGTGCGCATCGTCTATCTCGAAGACCTCCGCGCAACCCTGGGGCTGGCCGACAA
GCTGTGGCTGATGCTGTGGGCGCTCCACTTCCCGCGGCTCGCCACCTGCCGCCAGCAGCCGGGCGATCCCGCGGTGGTGT
TGTTCACATCGGGATCGGAAGGCAAGCCGAAGGGCGTCGTACTGTCGCATCAGGCGCTGCTGGCCAACGTCGCCCAGATC
CGCGCGGTGGTGGATATCTCGCCCGACGACAAGATCCTCAACGCCTTGCCGCTGTTTCATTCGTTCGGGTTGACGGCGGG
TTCGTTGCTGCCGGTGCTGTCCGGTGCCGATGTCTTCCTCTACCCCTCGCCCTTGCATTACCGGGTGATTCCGGAACTCG
CCTACGACCGCGGTTGCACCGTGCTGCTGGGCACCAGCACCTTCCTCGGCAATTACGCCAGGTTTGCCCACCCCTACGAC
TTCTTCCGCTTGCGCTACGTCATCGCCGGCGCCGAAAAGCTGTCTGAAGCGGTGCGCACCAGCTGGTTCGAGAAGTTCGG
CATCCGCATCTTCGAAGGTTACGGCGCCACCGAGACCGCGCCCGTGCTGGCGGTGAATACGCCGATGGCCTACCGCAGCG
GCACCGTCGGGCAACTGCTTCCCGGTCTGCACGCCAAGTTGCTCGCGGTGCCCGGCATCGACCGCGGCGGCATACTCCAC
GTCAGCGGGCCCAACCTCATGTCCGGCTACCTGCGGGTCGAACAACCCGGCGTGCTGCAGCCGCCGTCGTCCGCAGCCGG
CGAAGGGTGGTACGAAACCGGCGACGTGGTCGATATCGACGACGACGGCTTCCTGCGCATCGTCGGCCGTGTAAAGCGCT
TCGCCAAGGTCGCGGGTGAAATGGTGTCGCTCGAATCCGTCGAGAAACTGGCCGTGCAGACCGCGTCGGAGTTCGCCCAC
GCGGCCTCCACCCAGCCCGACCCGGCACGCGGCGAAAGCATCGTGCTGTTCTCCACCGACCCGGCCCTGACCCGCGAACG
CCTGCAGGCCGCGGCGCGCGACGGCGGCTGGCCGGAGATTGCGGTCCCCCGGCGCATTGTCCCCGTCGACGCGCTGCCGC
TGCTGGGCACCGGCAAGATCGACTACGTGACGCTCAAACGGTGGGCGGAAGCAGCGTGA

Upstream 100 bases:

>100_bases
ATCTCGCCAGCCGCCTGTGAATGTCATGTCGAAATGTCTGGACGCGTAATCACTTTGACGGCATGATCCGGGTTCCCCTC
GCCCGAATAGGTAAGCGGTC

Downstream 100 bases:

>100_bases
GCCGCCCGACCTGCAACACCCGCCGTCGCCTGCTGCTGGCTGCGGGCGGGGTCGCGTTGGCGGGCACCGCGGCCGGCTTC
GCAGCGGCGCGCCCGCTGCT

Product: bifunctional Aas protein

Products: NA

Alternate protein names: 2-acylglycerophosphoethanolamine acyltransferase; 2-acyl-GPE acyltransferase; Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase; Acyl-[acyl-carrier-protein] synthetase; Acyl-ACP synthetase; Long-chain-fatty-acid--[acyl-carrier-protein] ligase [H]

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MPVIRFVLRLLLGTLFSVRVRGDNASLSARRLLIVANHESFLDGLLLGLFLPADPVFVVHTGVTRRFWFRLALRLVDHLA
VDPTNPMAMKRVIRLLEEGRPVVIFPEGRITVTGSLMKVYEGPAFVAAKTGATIVPVRLDGAARSYFSRVAGRHPRRMLP
RITLSIQPPTRIEMPEAPTAKARRQKAGEAMRRLMQEMLFASRPSQTLFDALLDTAALHGRQRAVVEDVKQVEYSYGDLI
KMSLALGRLGSRLGGPGERIGVLLPNLAPTLGLVFGLNAFGRTPAMLNYTAGTEGLQAACTAACLRTVITSRAFLEQARL
TERVTALEGVRIVYLEDLRATLGLADKLWLMLWALHFPRLATCRQQPGDPAVVLFTSGSEGKPKGVVLSHQALLANVAQI
RAVVDISPDDKILNALPLFHSFGLTAGSLLPVLSGADVFLYPSPLHYRVIPELAYDRGCTVLLGTSTFLGNYARFAHPYD
FFRLRYVIAGAEKLSEAVRTSWFEKFGIRIFEGYGATETAPVLAVNTPMAYRSGTVGQLLPGLHAKLLAVPGIDRGGILH
VSGPNLMSGYLRVEQPGVLQPPSSAAGEGWYETGDVVDIDDDGFLRIVGRVKRFAKVAGEMVSLESVEKLAVQTASEFAH
AASTQPDPARGESIVLFSTDPALTRERLQAAARDGGWPEIAVPRRIVPVDALPLLGTGKIDYVTLKRWAEAA

Sequences:

>Translated_712_residues
MPVIRFVLRLLLGTLFSVRVRGDNASLSARRLLIVANHESFLDGLLLGLFLPADPVFVVHTGVTRRFWFRLALRLVDHLA
VDPTNPMAMKRVIRLLEEGRPVVIFPEGRITVTGSLMKVYEGPAFVAAKTGATIVPVRLDGAARSYFSRVAGRHPRRMLP
RITLSIQPPTRIEMPEAPTAKARRQKAGEAMRRLMQEMLFASRPSQTLFDALLDTAALHGRQRAVVEDVKQVEYSYGDLI
KMSLALGRLGSRLGGPGERIGVLLPNLAPTLGLVFGLNAFGRTPAMLNYTAGTEGLQAACTAACLRTVITSRAFLEQARL
TERVTALEGVRIVYLEDLRATLGLADKLWLMLWALHFPRLATCRQQPGDPAVVLFTSGSEGKPKGVVLSHQALLANVAQI
RAVVDISPDDKILNALPLFHSFGLTAGSLLPVLSGADVFLYPSPLHYRVIPELAYDRGCTVLLGTSTFLGNYARFAHPYD
FFRLRYVIAGAEKLSEAVRTSWFEKFGIRIFEGYGATETAPVLAVNTPMAYRSGTVGQLLPGLHAKLLAVPGIDRGGILH
VSGPNLMSGYLRVEQPGVLQPPSSAAGEGWYETGDVVDIDDDGFLRIVGRVKRFAKVAGEMVSLESVEKLAVQTASEFAH
AASTQPDPARGESIVLFSTDPALTRERLQAAARDGGWPEIAVPRRIVPVDALPLLGTGKIDYVTLKRWAEAA
>Mature_711_residues
PVIRFVLRLLLGTLFSVRVRGDNASLSARRLLIVANHESFLDGLLLGLFLPADPVFVVHTGVTRRFWFRLALRLVDHLAV
DPTNPMAMKRVIRLLEEGRPVVIFPEGRITVTGSLMKVYEGPAFVAAKTGATIVPVRLDGAARSYFSRVAGRHPRRMLPR
ITLSIQPPTRIEMPEAPTAKARRQKAGEAMRRLMQEMLFASRPSQTLFDALLDTAALHGRQRAVVEDVKQVEYSYGDLIK
MSLALGRLGSRLGGPGERIGVLLPNLAPTLGLVFGLNAFGRTPAMLNYTAGTEGLQAACTAACLRTVITSRAFLEQARLT
ERVTALEGVRIVYLEDLRATLGLADKLWLMLWALHFPRLATCRQQPGDPAVVLFTSGSEGKPKGVVLSHQALLANVAQIR
AVVDISPDDKILNALPLFHSFGLTAGSLLPVLSGADVFLYPSPLHYRVIPELAYDRGCTVLLGTSTFLGNYARFAHPYDF
FRLRYVIAGAEKLSEAVRTSWFEKFGIRIFEGYGATETAPVLAVNTPMAYRSGTVGQLLPGLHAKLLAVPGIDRGGILHV
SGPNLMSGYLRVEQPGVLQPPSSAAGEGWYETGDVVDIDDDGFLRIVGRVKRFAKVAGEMVSLESVEKLAVQTASEFAHA
ASTQPDPARGESIVLFSTDPALTRERLQAAARDGGWPEIAVPRRIVPVDALPLLGTGKIDYVTLKRWAEAA

Specific function: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI38505220, Length=510, Percent_Identity=26.8627450980392, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI156151445, Length=375, Percent_Identity=26.9333333333333, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI187761345, Length=386, Percent_Identity=27.4611398963731, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI187761343, Length=386, Percent_Identity=27.4611398963731, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI40807491, Length=339, Percent_Identity=26.8436578171091, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI57165412, Length=347, Percent_Identity=27.6657060518732, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI57165410, Length=347, Percent_Identity=26.8011527377522, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI42544132, Length=373, Percent_Identity=24.6648793565684, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI115511026, Length=374, Percent_Identity=24.331550802139, Blast_Score=77, Evalue=8e-14,
Organism=Escherichia coli, GI1789201, Length=710, Percent_Identity=54.2253521126761, Blast_Score=796, Evalue=0.0,
Organism=Escherichia coli, GI1788107, Length=485, Percent_Identity=28.659793814433, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI145693145, Length=356, Percent_Identity=28.0898876404494, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1786810, Length=506, Percent_Identity=23.3201581027668, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17558820, Length=342, Percent_Identity=28.0701754385965, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32563687, Length=344, Percent_Identity=28.7790697674419, Blast_Score=106, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71994690, Length=358, Percent_Identity=28.4916201117318, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994694, Length=358, Percent_Identity=28.4916201117318, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71994703, Length=358, Percent_Identity=28.4916201117318, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560308, Length=370, Percent_Identity=26.7567567567568, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17510401, Length=478, Percent_Identity=25.7322175732218, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=363, Percent_Identity=26.9972451790634, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=287, Percent_Identity=27.8745644599303, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319699, Length=361, Percent_Identity=24.6537396121884, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320852, Length=157, Percent_Identity=27.3885350318471, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355181, Length=530, Percent_Identity=24.3396226415094, Blast_Score=106, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24581924, Length=543, Percent_Identity=24.6777163904236, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859661, Length=509, Percent_Identity=25.5402750491159, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF01553 Acyltransferase; PF00501 AMP-binding [H]

EC number: =2.3.1.40; =6.2.1.20 [H]

Molecular weight: Translated: 77538; Mature: 77407

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVIRFVLRLLLGTLFSVRVRGDNASLSARRLLIVANHESFLDGLLLGLFLPADPVFVVH
CCHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEE
TGVTRRFWFRLALRLVDHLAVDPTNPMAMKRVIRLLEEGRPVVIFPEGRITVTGSLMKVY
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHH
EGPAFVAAKTGATIVPVRLDGAARSYFSRVAGRHPRRMLPRITLSIQPPTRIEMPEAPTA
CCCEEEEECCCCEEEEEEECHHHHHHHHHHHCCCCHHHCCEEEEEECCCCCCCCCCCCCH
KARRQKAGEAMRRLMQEMLFASRPSQTLFDALLDTAALHGRQRAVVEDVKQVEYSYGDLI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KMSLALGRLGSRLGGPGERIGVLLPNLAPTLGLVFGLNAFGRTPAMLNYTAGTEGLQAAC
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCHHCCCCCCEEEECCCCCHHHHHH
TAACLRTVITSRAFLEQARLTERVTALEGVRIVYLEDLRATLGLADKLWLMLWALHFPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHCHHHHHHHHHHHHHCCHH
ATCRQQPGDPAVVLFTSGSEGKPKGVVLSHQALLANVAQIRAVVDISPDDKILNALPLFH
HHHHCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHEEEECCCCHHHHHHHHHHH
SFGLTAGSLLPVLSGADVFLYPSPLHYRVIPELAYDRGCTVLLGTSTFLGNYARFAHPYD
HHCCCHHHHHHHHCCCCEEEECCCCCEEECHHHHHCCCCEEEEECHHHHHCHHHHCCCHH
FFRLRYVIAGAEKLSEAVRTSWFEKFGIRIFEGYGATETAPVLAVNTPMAYRSGTVGQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCCHHCCCCHHHHH
PGLHAKLLAVPGIDRGGILHVSGPNLMSGYLRVEQPGVLQPPSSAAGEGWYETGDVVDID
CCCHHHEEECCCCCCCCEEEECCCCHHCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEC
DDGFLRIVGRVKRFAKVAGEMVSLESVEKLAVQTASEFAHAASTQPDPARGESIVLFSTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
PALTRERLQAAARDGGWPEIAVPRRIVPVDALPLLGTGKIDYVTLKRWAEAA
CHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEHHHHHCCC
>Mature Secondary Structure 
PVIRFVLRLLLGTLFSVRVRGDNASLSARRLLIVANHESFLDGLLLGLFLPADPVFVVH
CHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCEEEEE
TGVTRRFWFRLALRLVDHLAVDPTNPMAMKRVIRLLEEGRPVVIFPEGRITVTGSLMKVY
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHH
EGPAFVAAKTGATIVPVRLDGAARSYFSRVAGRHPRRMLPRITLSIQPPTRIEMPEAPTA
CCCEEEEECCCCEEEEEEECHHHHHHHHHHHCCCCHHHCCEEEEEECCCCCCCCCCCCCH
KARRQKAGEAMRRLMQEMLFASRPSQTLFDALLDTAALHGRQRAVVEDVKQVEYSYGDLI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KMSLALGRLGSRLGGPGERIGVLLPNLAPTLGLVFGLNAFGRTPAMLNYTAGTEGLQAAC
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHCCHHCCCCCCEEEECCCCCHHHHHH
TAACLRTVITSRAFLEQARLTERVTALEGVRIVYLEDLRATLGLADKLWLMLWALHFPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHCHHHHHHHHHHHHHCCHH
ATCRQQPGDPAVVLFTSGSEGKPKGVVLSHQALLANVAQIRAVVDISPDDKILNALPLFH
HHHHCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHEEEECCCCHHHHHHHHHHH
SFGLTAGSLLPVLSGADVFLYPSPLHYRVIPELAYDRGCTVLLGTSTFLGNYARFAHPYD
HHCCCHHHHHHHHCCCCEEEECCCCCEEECHHHHHCCCCEEEEECHHHHHCHHHHCCCHH
FFRLRYVIAGAEKLSEAVRTSWFEKFGIRIFEGYGATETAPVLAVNTPMAYRSGTVGQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCCHHCCCCHHHHH
PGLHAKLLAVPGIDRGGILHVSGPNLMSGYLRVEQPGVLQPPSSAAGEGWYETGDVVDID
CCCHHHEEECCCCCCCCEEEECCCCHHCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEC
DDGFLRIVGRVKRFAKVAGEMVSLESVEKLAVQTASEFAHAASTQPDPARGESIVLFSTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
PALTRERLQAAARDGGWPEIAVPRRIVPVDALPLLGTGKIDYVTLKRWAEAA
CHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA