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The map label for this gene is livM1 [H]

Identifier: 119896413

GI number: 119896413

Start: 138807

End: 139763

Strand: Direct

Name: livM1 [H]

Synonym: azo0121

Alternate gene names: 119896413

Gene position: 138807-139763 (Clockwise)

Preceding gene: 119896412

Following gene: 119896415

Centisome position: 3.17

GC content: 66.56

Gene sequence:

>957_bases
ATGAGCTACAACGACAAGTCGCTGTTCGACCGGGCCACGCCGGTGCTGTTCGGCGCGCTCTTCATCATCGGGCTGGTGGC
GCCGTTCGCGGTCTATCCCACCTTCCTGATGAAGATCCTGTGTTTCGGGCTGTTCGCCTGCGCGTTCAACCTGCTGCTCG
GCTTTGCCGGCCTGCTCTCGTTCGGCCACGCCGCCTTCCTCGGCAGCGCCGGCTACGTCTGCGGCATGCTGGTGCGCGAC
CTTGGCGTCACCCCCGAAGTCGGCATCATCGGCGGCACGCTGGCGGCCGGCGTGCTGGGCTGGGTGTTCGGCGTGCTGGC
GATCCGGCGCAGCGGCATCTACTTCGCGATGATCACGCTGGCGCTGTCGCAGATGGTGTTCTTCTTCGCGCTGCAGTGGA
AGGCGACCGGGGGCGAGGACGGCCTGCAGGGTGTGCCGCGCGGCCACCTGTTCGGGCTGATCGACCTCAGCAACAACCTG
GCGATGTATTACCTGGTGTTCGCCGTGTTCTGCGCCGGCTTCTTCATCATCTACCGCGCCATCCACTCGCCCTTCGGCCA
GATCCTGAAGGCGATCCGCGAGAACGAGCCGCGCGCGATCTCGCTCGGCTACGACGTCAGCAAGTACAAGCTGCTCGCCT
TCGTGCTGTCGGCCGCGCTTGCCGGGCTGGCCGGTGCCACCAAGACGCTGGTGTTCCAGCTCGCCTCGCTGACCGACGTG
CATTGGCACATGTCGGGCGAGGTGGTGCTGATGACCCTGCTCGGCGGCCTCGGCACCATCCTCGGCCCGCTGGTCGGCGC
CTCGGTCATCGTCAGCCTGCAGAGCGAACTTGCCGACAAGGTCGGCTCCTGGGTGACGGTGATCATGGGCGTGATCTTCG
TGCTGTGCGTGCTGCTGTTCCGCCGCGGCATCGTCGGCGAGCTGCAGGCGCTGATCCGGCGCAGCGGCATCAACTAG

Upstream 100 bases:

>100_bases
GGCGGTGGTGGTGTTCTTCATCATGGTCATCGTGCTGCTGGTGCGCCCGGCCGGACTGTTCGGCAAGGCCGCCTGAGGCG
TGCGACAAGGAAAAGCGCTC

Downstream 100 bases:

>100_bases
ACAAGGCGAGGAGGAGACAGGCGGGCGCGGCATTGCCGCCTCGCCCACAACACGCGCGGCGGGCGTCTTCGCCCGACCGC
CGCGGGCAGTACGGGCCGGC

Product: putative branched-chain amino acid transport permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSYNDKSLFDRATPVLFGALFIIGLVAPFAVYPTFLMKILCFGLFACAFNLLLGFAGLLSFGHAAFLGSAGYVCGMLVRD
LGVTPEVGIIGGTLAAGVLGWVFGVLAIRRSGIYFAMITLALSQMVFFFALQWKATGGEDGLQGVPRGHLFGLIDLSNNL
AMYYLVFAVFCAGFFIIYRAIHSPFGQILKAIRENEPRAISLGYDVSKYKLLAFVLSAALAGLAGATKTLVFQLASLTDV
HWHMSGEVVLMTLLGGLGTILGPLVGASVIVSLQSELADKVGSWVTVIMGVIFVLCVLLFRRGIVGELQALIRRSGIN

Sequences:

>Translated_318_residues
MSYNDKSLFDRATPVLFGALFIIGLVAPFAVYPTFLMKILCFGLFACAFNLLLGFAGLLSFGHAAFLGSAGYVCGMLVRD
LGVTPEVGIIGGTLAAGVLGWVFGVLAIRRSGIYFAMITLALSQMVFFFALQWKATGGEDGLQGVPRGHLFGLIDLSNNL
AMYYLVFAVFCAGFFIIYRAIHSPFGQILKAIRENEPRAISLGYDVSKYKLLAFVLSAALAGLAGATKTLVFQLASLTDV
HWHMSGEVVLMTLLGGLGTILGPLVGASVIVSLQSELADKVGSWVTVIMGVIFVLCVLLFRRGIVGELQALIRRSGIN
>Mature_317_residues
SYNDKSLFDRATPVLFGALFIIGLVAPFAVYPTFLMKILCFGLFACAFNLLLGFAGLLSFGHAAFLGSAGYVCGMLVRDL
GVTPEVGIIGGTLAAGVLGWVFGVLAIRRSGIYFAMITLALSQMVFFFALQWKATGGEDGLQGVPRGHLFGLIDLSNNLA
MYYLVFAVFCAGFFIIYRAIHSPFGQILKAIRENEPRAISLGYDVSKYKLLAFVLSAALAGLAGATKTLVFQLASLTDVH
WHMSGEVVLMTLLGGLGTILGPLVGASVIVSLQSELADKVGSWVTVIMGVIFVLCVLLFRRGIVGELQALIRRSGIN

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=279, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 33996; Mature: 33865

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYNDKSLFDRATPVLFGALFIIGLVAPFAVYPTFLMKILCFGLFACAFNLLLGFAGLLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGHAAFLGSAGYVCGMLVRDLGVTPEVGIIGGTLAAGVLGWVFGVLAIRRSGIYFAMITL
HHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ALSQMVFFFALQWKATGGEDGLQGVPRGHLFGLIDLSNNLAMYYLVFAVFCAGFFIIYRA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
IHSPFGQILKAIRENEPRAISLGYDVSKYKLLAFVLSAALAGLAGATKTLVFQLASLTDV
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HWHMSGEVVLMTLLGGLGTILGPLVGASVIVSLQSELADKVGSWVTVIMGVIFVLCVLLF
HEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGIVGELQALIRRSGIN
HCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYNDKSLFDRATPVLFGALFIIGLVAPFAVYPTFLMKILCFGLFACAFNLLLGFAGLLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]