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The map label for this gene is polC [H]

Identifier: 119896359

GI number: 119896359

Start: 78461

End: 79156

Strand: Direct

Name: polC [H]

Synonym: azo0067

Alternate gene names: 119896359

Gene position: 78461-79156 (Clockwise)

Preceding gene: 119896355

Following gene: 119896361

Centisome position: 1.79

GC content: 70.55

Gene sequence:

>696_bases
GTGCACCACGGGCTTCGGCGACGCGCTATCGTTCGCGCCCTGCGCTGGATTTCCCTCACCCTCGTCGCCGCGGAAGATCA
CTTGGACACCTACGCCGTCATCGACTTCGAAACCACCGGCATGGCCCCCGAGCATGGCGCCCGCCCGACCGAGATCGCCG
TGGTGCTGGTGCGCAACGGCTGCGTGATCGACCGCTACCAGAGCCTGATGAACGCCGGCGTGCACGTGCCCTACGAAATC
CAGGCGCTGACCGGCATCACCAACGCGATGGTGCGCGCAGCGCCGCCGCTGGCGCAGGTGATGGCGCAAGCGGCCGATTT
CGTCGGCAGCCACGCGCTGGTTGCGCACAACGCCGCGTTCGACCGCAAGTTCTGGGACGCCGAGCTGGACCGCCTGGGGC
GGCGGCGCGAAGCCGATTTCGTGTGCTCGCTGCTGCTGTCGCGCCGCGTCTTTCCGGACTCGCCCAACCACAAGCTCGGC
ACCCTGGTGCGCACCCTCGGCTTGCCGGCCAGCGGGCGCTTCCACCGGGCGCTCGCCGACGCCGAGGCAACCGCGCAGCT
GTTCGCCCGCATCGCCCACACGCTGTGCGAGCGCTATGCGCTGGCGGCGCTGGACCACGCGCTGCTGATGAAGATCCAGA
AGACCGCCCGCGGCGCGCTCGACGGCTGCATCGCCCGCCACCGCGCAGCCGCCTGA

Upstream 100 bases:

>100_bases
GCAGGCAGTGGGAATCTCGCGCAGCAGGACGGCGGCGGTCATCACGTGTCTCCGTGGAATCGTGTCGGGGGCCGGAATTG
TGGCCCAGAGCCGGTCCGCG

Downstream 100 bases:

>100_bases
GCCGGGCTCAGTCGATCTCGGCCGGCGCGAAGAAGGCCTCGTCGAAGCCCGCCGCTGCCGCCCCGCCGGGCAGCAGCGCG
CCGTCGCGCAGGTCGAACTC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MHHGLRRRAIVRALRWISLTLVAAEDHLDTYAVIDFETTGMAPEHGARPTEIAVVLVRNGCVIDRYQSLMNAGVHVPYEI
QALTGITNAMVRAAPPLAQVMAQAADFVGSHALVAHNAAFDRKFWDAELDRLGRRREADFVCSLLLSRRVFPDSPNHKLG
TLVRTLGLPASGRFHRALADAEATAQLFARIAHTLCERYALAALDHALLMKIQKTARGALDGCIARHRAAA

Sequences:

>Translated_231_residues
MHHGLRRRAIVRALRWISLTLVAAEDHLDTYAVIDFETTGMAPEHGARPTEIAVVLVRNGCVIDRYQSLMNAGVHVPYEI
QALTGITNAMVRAAPPLAQVMAQAADFVGSHALVAHNAAFDRKFWDAELDRLGRRREADFVCSLLLSRRVFPDSPNHKLG
TLVRTLGLPASGRFHRALADAEATAQLFARIAHTLCERYALAALDHALLMKIQKTARGALDGCIARHRAAA
>Mature_231_residues
MHHGLRRRAIVRALRWISLTLVAAEDHLDTYAVIDFETTGMAPEHGARPTEIAVVLVRNGCVIDRYQSLMNAGVHVPYEI
QALTGITNAMVRAAPPLAQVMAQAADFVGSHALVAHNAAFDRKFWDAELDRLGRRREADFVCSLLLSRRVFPDSPNHKLG
TLVRTLGLPASGRFHRALADAEATAQLFARIAHTLCERYALAALDHALLMKIQKTARGALDGCIARHRAAA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25354; Mature: 25354

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHGLRRRAIVRALRWISLTLVAAEDHLDTYAVIDFETTGMAPEHGARPTEIAVVLVRNG
CCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEECC
CVIDRYQSLMNAGVHVPYEIQALTGITNAMVRAAPPLAQVMAQAADFVGSHALVAHNAAF
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCHH
DRKFWDAELDRLGRRREADFVCSLLLSRRVFPDSPNHKLGTLVRTLGLPASGRFHRALAD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
AEATAQLFARIAHTLCERYALAALDHALLMKIQKTARGALDGCIARHRAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHHGLRRRAIVRALRWISLTLVAAEDHLDTYAVIDFETTGMAPEHGARPTEIAVVLVRNG
CCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEECC
CVIDRYQSLMNAGVHVPYEIQALTGITNAMVRAAPPLAQVMAQAADFVGSHALVAHNAAF
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCHH
DRKFWDAELDRLGRRREADFVCSLLLSRRVFPDSPNHKLGTLVRTLGLPASGRFHRALAD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
AEATAQLFARIAHTLCERYALAALDHALLMKIQKTARGALDGCIARHRAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]