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The map label for this gene is mreB [H]

Identifier: 229220634

GI number: 229220634

Start: 573182

End: 574231

Strand: Direct

Name: mreB [H]

Synonym: Sama_0467

Alternate gene names: 229220634

Gene position: 573182-574231 (Clockwise)

Preceding gene: 119773606

Following gene: 119773608

Centisome position: 13.31

GC content: 54.95

Gene sequence:

>1050_bases
ATGTTCAAAAAGCTGCGTGGCATTTTTTCCAATGATCTTTCGATCGACCTGGGTACCGCCAACACCCTTATCTATGTGCG
TGAAGAAGGTATTGTCCTCAATGAACCTTCGGTGGTGGCAATTCGTAACGAACGCAACAGCTCAGGGCAAAAGTCCGTGG
CTGCTGTGGGTACCGAAGCCAAGCTGATGCTCGGACGTACCCCTGGCAATATTCAGGCGATTCGCCCGATGAAAGACGGT
GTAATCGCCGACTTTTATGTGACTGAGAAGATGCTGCAGCACTTCATTAAGCAAGTTCACAACAACAGTTTCTTTCGCCC
AAGCCCCCGGGTGCTGGTGTGCGTGCCAGTAGGAGCCACCCAGGTGGAGCGCCGGGCCATCCGTGAATCAGCCATGGGCG
CCGGTGCCCGCGAAGTGTATCTGATTGAAGAGCCAATGGCGGCCGCCATCGGTGCCGGTCTGCCGGTTTCTGAAGCGACA
GGCTCCATGGTGGTGGATATCGGTGGTGGTACCACTGAAGTGGCCATCATCTCCCTGAACGGTGTGGTGTACTCATCGTC
TGTACGTATCGGTGGTGATAAGTTTGACGATGCCATTATCAATTATGTGCGTCGTAACTACGGCAGCCTGATTGGTGAGG
CCACAGCCGAACGTATCAAACACACCATAGGTACTGCTTATCCCGGCGATGAGGTGCTGGAAATTGAAGTGCGTGGTCGT
AACCTGGCCGAAGGTGTGCCAAGAAGCTTCACCCTCAACAGCAACGAAATTCTTGAGGCCCTGCAAGAGCCGCTGTCGGG
TATCGTCAGTGCCGTGATGGTGGCACTGGAGCAGTCTCCACCGGAACTGGCTTCTGATATCTCAGAGCGCGGCATGGTGC
TCACAGGTGGTGGTGCGCTGTTGCGTGACCTCGACCGCCTGCTGATGCAGGAAACCGGTATCCCTGTGATGGTAGCCGAA
GATCCGCTGACCTGTGTTGCCAGAGGCGGTGGTAAGGCCCTCGAAATGATCGACATGCACGGTGGCGATCTCTTCTCCGA
AGAAAATTAA

Upstream 100 bases:

>100_bases
CGATTGTTAACCTCCCCAGTCTTGTGGAATCAGGGTGGCATTGATAAAGTTAGCTGATTTTTCTTTTCTCTGGCTCCTCT
CAGAAAAACAGGCTGGTTAC

Downstream 100 bases:

>100_bases
CACCACAGGTGAAAGAGGCGGTAAGGCTACCGCCTCCTTTGTTTTATGAAGCCTATTTTTGTTCGCGGCGTCTCAAATCA
ATTCCGACTGACACTGGCAA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRNERNSSGQKSVAAVGTEAKLMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALLRDLDRLLMQETGIPVMVAE
DPLTCVARGGGKALEMIDMHGGDLFSEEN

Sequences:

>Translated_349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRNERNSSGQKSVAAVGTEAKLMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALLRDLDRLLMQETGIPVMVAE
DPLTCVARGGGKALEMIDMHGGDLFSEEN
>Mature_349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRNERNSSGQKSVAAVGTEAKLMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALLRDLDRLLMQETGIPVMVAE
DPLTCVARGGGKALEMIDMHGGDLFSEEN

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=348, Percent_Identity=90.5172413793103, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI1786870, Length=356, Percent_Identity=25, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37356; Mature: 37356

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRNERNSSGQKSVAAVGTEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCCHHEECCCCE
KLMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT
EEEEECCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
CEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL
CHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLLMQETGIPVMVAEDPLTCVARGGGKALEMIDMHGGDLFSEEN
HHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRNERNSSGQKSVAAVGTEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCCHHEECCCCE
KLMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT
EEEEECCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
CEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL
CHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLLMQETGIPVMVAEDPLTCVARGGGKALEMIDMHGGDLFSEEN
HHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]