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The map label for this gene is atpB [H]

Identifier: 119776782

GI number: 119776782

Start: 4299972

End: 4300766

Strand: Reverse

Name: atpB [H]

Synonym: Sama_3650

Alternate gene names: 119776782

Gene position: 4300766-4299972 (Counterclockwise)

Preceding gene: 119776783

Following gene: 119776781

Centisome position: 99.88

GC content: 50.19

Gene sequence:

>795_bases
ATGGCTGCAACTGGTGAAGCGTTAACACCGCAGGGCTATATCCAGCATCACCTGACCAACCTTTCCGTTGGTGAAGGATT
CTGGACATGGCATATTGATTCGTTGCTCTTTTCGGTTGGTCTTGGTGTTCTGTTCCTGTGGATTTTCCGTAGCGTTGGCA
AGAAAGCGACTACAGGCGTTCCCGGCAAGCTTCAGTGCTTTGTCGAGATGATCGTCGAGTTCGTGGACAACAGCGTGAAA
GAAACCTTCCACGGCCGTAATGCCCTGATCGCTCCTCTCGCTCTGACCATCTTCGTTTGGGTTTTCATGATGAACTTCAT
GGACATGGTGCCAGTTGACTGGCTGCCACACACCGCCGCTATGCTGGGTGTGCCTTACCTGAAAGTGGTTCCGACGACTG
ACCTGAACATCACCTTCAGCCTCGCGCTGGGTGTGTTTTTGCTGATTATTTACTACAGCATCAAGGTCAAGGGAGTGTCT
GGCTTCGTGAAAGAACTGACACTGCAGCCCTTTAACCACTGGGCAATGATACCCGTCAACCTCCTGCTGGAATCAGTTAC
CCTGATAGCCAAGCCAATCTCATTGGCTCTGCGTCTATTCGGTAACCTGTATGCGGGTGAGTTGATCTTCATCCTTATTG
CGCTGATGTATGGTGCCAACTGGCTGATCGCCTCTCTGGGTGTAACCCTGCAACTGGGTTGGTTGATCTTCCACATTCTG
GTTATCACACTGCAAGCGTTTATCTTCATGATGCTGACTATTGTTTACCTCAGCATGGCGCATGAAGATCATTAA

Upstream 100 bases:

>100_bases
AAAATCGTCTTTATGCCGCTTTTCGTTTGCTACTCACTGGCACTCCTGGTGCATTGGACAGCGCCTTTATACTTCAAGCA
AAAGTAAAGTGGGATGAATC

Downstream 100 bases:

>100_bases
GGATTGCTGAAGAAATTTTTTTAAACTAAATCATCAACTAATTTAGATTTAGATACTGGAGATACAGATGGAAACTATTC
TGGGCTTTACTGCAATCGCT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MAATGEALTPQGYIQHHLTNLSVGEGFWTWHIDSLLFSVGLGVLFLWIFRSVGKKATTGVPGKLQCFVEMIVEFVDNSVK
ETFHGRNALIAPLALTIFVWVFMMNFMDMVPVDWLPHTAAMLGVPYLKVVPTTDLNITFSLALGVFLLIIYYSIKVKGVS
GFVKELTLQPFNHWAMIPVNLLLESVTLIAKPISLALRLFGNLYAGELIFILIALMYGANWLIASLGVTLQLGWLIFHIL
VITLQAFIFMMLTIVYLSMAHEDH

Sequences:

>Translated_264_residues
MAATGEALTPQGYIQHHLTNLSVGEGFWTWHIDSLLFSVGLGVLFLWIFRSVGKKATTGVPGKLQCFVEMIVEFVDNSVK
ETFHGRNALIAPLALTIFVWVFMMNFMDMVPVDWLPHTAAMLGVPYLKVVPTTDLNITFSLALGVFLLIIYYSIKVKGVS
GFVKELTLQPFNHWAMIPVNLLLESVTLIAKPISLALRLFGNLYAGELIFILIALMYGANWLIASLGVTLQLGWLIFHIL
VITLQAFIFMMLTIVYLSMAHEDH
>Mature_263_residues
AATGEALTPQGYIQHHLTNLSVGEGFWTWHIDSLLFSVGLGVLFLWIFRSVGKKATTGVPGKLQCFVEMIVEFVDNSVKE
TFHGRNALIAPLALTIFVWVFMMNFMDMVPVDWLPHTAAMLGVPYLKVVPTTDLNITFSLALGVFLLIIYYSIKVKGVSG
FVKELTLQPFNHWAMIPVNLLLESVTLIAKPISLALRLFGNLYAGELIFILIALMYGANWLIASLGVTLQLGWLIFHILV
ITLQAFIFMMLTIVYLSMAHEDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=277, Percent_Identity=60.2888086642599, Blast_Score=311, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29519; Mature: 29388

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AATGEALTPQGYIQHHLTNLSVGEGFWTWHIDSLLFSVGLGVLFLWIFRSVGKKATTGV
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PGKLQCFVEMIVEFVDNSVKETFHGRNALIAPLALTIFVWVFMMNFMDMVPVDWLPHTAA
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
MLGVPYLKVVPTTDLNITFSLALGVFLLIIYYSIKVKGVSGFVKELTLQPFNHWAMIPVN
HHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHH
LLLESVTLIAKPISLALRLFGNLYAGELIFILIALMYGANWLIASLGVTLQLGWLIFHIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VITLQAFIFMMLTIVYLSMAHEDH
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA