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The map label for this gene is ctaC [H]

Identifier: 119776615

GI number: 119776615

Start: 4115112

End: 4116674

Strand: Direct

Name: ctaC [H]

Synonym: Sama_3483

Alternate gene names: 119776615

Gene position: 4115112-4116674 (Clockwise)

Preceding gene: 119776614

Following gene: 119776616

Centisome position: 95.56

GC content: 54.77

Gene sequence:

>1563_bases
GTGAAGCAATGGTTGTATTGTTTCGCGGCGGCTTTATTGGCCCCGCCCATCTTTGCGGCTGACATGCCGCTCAACATGAC
ACAAGGTGTTACTGAGATAAGTGGCAAGGTCTATGGCCTGCACATGACTATCCTGTACATCTGCTGTGCCATAGGTGTAG
TGGTTTTTGGCGCCATGATTTACGCCATGATAAACCACCGCAAATCAAAAGGGGCGGTTGCCGCCCAATTTCACGAAAGC
ACCAAGGTGGAAATCGCCTGGACTCTGGTGCCCTTTCTCATCCTGATTGCCATGGCTATTCCGGCAACCAAGACCCTTAT
CGCCATGGAAGATCCGTCCAATGCCGACTTGACCATCAAGATCACCGGCTCCCAATGGAAGTGGCACTACGATTACTTTG
ACCACGACTTCGGTTTCTACAGCATCCTGGCTACACCCAGAAGCCAAATCGAAGGTGCAGAAGCAAAAGGCGATCACTAC
TTGTTGGAAGTGGATAAGCATCTGGTGCTGCCCACCAACCGCAAGGTGCGCTTTTTGATGACCTCCGACGACGTCATTCA
CTCCTGGTGGGTGCCCGCGTTTGCCGTTAAAAAGGATGCCAATCCGGGCTTTATCAACGAAGCATGGACCCGAATAGATA
AACCTGGGATTTATCACGGCCAGTGTGCCGAGCTGTGCGGCAAAGACCACGGCTTTATGCCAATCGTGGTTGAGGTTTTG
CCCGAAGCAGAGTTTGACACATGGGTTGAAAACCAGAAGCAACTGGCAAGCAACGCCGCTGCCGAAGCCGCTGCGGCATT
GAACCAAACCCTTTCCATGGAAGAACTGATGGTGCAGGGTGAAAAGGTGTACATGGCCAGCTGCGCCGCCTGTCACCAAC
CCAATGGTATGGGCCTGCCCGGCGTATTCCCCGCTCTCAAGGGCAGTGCTATTGCCATGGGTCCGGTAGACAAGCATCTC
GACATAGTGATCAACGGTAAATCCGGTACAGCCATGCAGGCGTTTAACAAGCAGTTATCTGCCACAGAGATTGCCGCTGT
TGTGACCTATGAGCGTAATGCATGGGGCAACAATACCGGTGATACGGTGCAGGCATCTGATGTCAACGGCCATGGCAGTG
ACAGCACTCCCACCGCGCAAACCGGGATGCAAGAAACTGATCAGGCGCCCCCCGCCAGCGCAGCCGAGACATCGACCGAA
GCTCCCCCTGCTGCCGAATCCACTGCCGACGAGCCTTCAGCCGATGAGCCCATGTCGATGGATGCTTTGATGGCCCGTGG
TGAGCAAGTGTACATGGCCTCTTGCGCGGCCTGTCACCAAGCCAATGGTGCCGGTTTGCCCGGTGCGTTTCCCGCCATCA
AGGGAAGCCCTATCGCTACAGGCCCCATCGCCAATCACCTCGACATAGTTATTCACGGCAAAGCCGGAACGGCTATGCAG
GCCTTTGGCTCAATGTTGTCTGCCAGGGACATTGCTGCGGTGGTGACCTATGAACGTAACGCCTGGGATAACAACACCGG
CGATAGCGTTCAGGCCACCGACGTAAACAATCATGGAAAGTAG

Upstream 100 bases:

>100_bases
CGTTGCTTTTTGTGGGAACCGAAGAGTTTGCATAGAGCAGAGACTTACTGTGTGGCTCTTCTTTGTAGTTGCTTGATGCA
ATTGACAGAGGAGATGTCTT

Downstream 100 bases:

>100_bases
GGGAACGATAATGACAACCACGACCCACGATACCCATCAGGGCGTCCATGACGAACACCATCATGGCCCGGCCAAGGGCA
TAATGCGCTGGATATTAACA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKQWLYCFAAALLAPPIFAADMPLNMTQGVTEISGKVYGLHMTILYICCAIGVVVFGAMIYAMINHRKSKGAVAAQFHES
TKVEIAWTLVPFLILIAMAIPATKTLIAMEDPSNADLTIKITGSQWKWHYDYFDHDFGFYSILATPRSQIEGAEAKGDHY
LLEVDKHLVLPTNRKVRFLMTSDDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYHGQCAELCGKDHGFMPIVVEVL
PEAEFDTWVENQKQLASNAAAEAAAALNQTLSMEELMVQGEKVYMASCAACHQPNGMGLPGVFPALKGSAIAMGPVDKHL
DIVINGKSGTAMQAFNKQLSATEIAAVVTYERNAWGNNTGDTVQASDVNGHGSDSTPTAQTGMQETDQAPPASAAETSTE
APPAAESTADEPSADEPMSMDALMARGEQVYMASCAACHQANGAGLPGAFPAIKGSPIATGPIANHLDIVIHGKAGTAMQ
AFGSMLSARDIAAVVTYERNAWDNNTGDSVQATDVNNHGK

Sequences:

>Translated_520_residues
MKQWLYCFAAALLAPPIFAADMPLNMTQGVTEISGKVYGLHMTILYICCAIGVVVFGAMIYAMINHRKSKGAVAAQFHES
TKVEIAWTLVPFLILIAMAIPATKTLIAMEDPSNADLTIKITGSQWKWHYDYFDHDFGFYSILATPRSQIEGAEAKGDHY
LLEVDKHLVLPTNRKVRFLMTSDDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYHGQCAELCGKDHGFMPIVVEVL
PEAEFDTWVENQKQLASNAAAEAAAALNQTLSMEELMVQGEKVYMASCAACHQPNGMGLPGVFPALKGSAIAMGPVDKHL
DIVINGKSGTAMQAFNKQLSATEIAAVVTYERNAWGNNTGDTVQASDVNGHGSDSTPTAQTGMQETDQAPPASAAETSTE
APPAAESTADEPSADEPMSMDALMARGEQVYMASCAACHQANGAGLPGAFPAIKGSPIATGPIANHLDIVIHGKAGTAMQ
AFGSMLSARDIAAVVTYERNAWDNNTGDSVQATDVNNHGK
>Mature_520_residues
MKQWLYCFAAALLAPPIFAADMPLNMTQGVTEISGKVYGLHMTILYICCAIGVVVFGAMIYAMINHRKSKGAVAAQFHES
TKVEIAWTLVPFLILIAMAIPATKTLIAMEDPSNADLTIKITGSQWKWHYDYFDHDFGFYSILATPRSQIEGAEAKGDHY
LLEVDKHLVLPTNRKVRFLMTSDDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYHGQCAELCGKDHGFMPIVVEVL
PEAEFDTWVENQKQLASNAAAEAAAALNQTLSMEELMVQGEKVYMASCAACHQPNGMGLPGVFPALKGSAIAMGPVDKHL
DIVINGKSGTAMQAFNKQLSATEIAAVVTYERNAWGNNTGDTVQASDVNGHGSDSTPTAQTGMQETDQAPPASAAETSTE
APPAAESTADEPSADEPMSMDALMARGEQVYMASCAACHQANGAGLPGAFPAIKGSPIATGPIANHLDIVIHGKAGTAMQ
AFGSMLSARDIAAVVTYERNAWDNNTGDSVQATDVNNHGK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=168, Percent_Identity=38.6904761904762, Blast_Score=143, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6226540, Length=234, Percent_Identity=29.4871794871795, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 55665; Mature: 55665

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00018 EF_HAND_1 ; PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQWLYCFAAALLAPPIFAADMPLNMTQGVTEISGKVYGLHMTILYICCAIGVVVFGAMI
CCHHHHHHHHHHHCCCCEECCCCCCHHCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVAAQFHESTKVEIAWTLVPFLILIAMAIPATKTLIAMEDPSNADLTIK
HHHHHCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
ITGSQWKWHYDYFDHDFGFYSILATPRSQIEGAEAKGDHYLLEVDKHLVLPTNRKVRFLM
EECCCEEEEECCCCCCCCEEEEEECCHHHCCCCCCCCCEEEEEECCEEECCCCCCEEEEE
TSDDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYHGQCAELCGKDHGFMPIVVEVL
ECCCHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCCCCEEHEECC
PEAEFDTWVENQKQLASNAAAEAAAALNQTLSMEELMVQGEKVYMASCAACHQPNGMGLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEHHHHHCCCCCCCCC
GVFPALKGSAIAMGPVDKHLDIVINGKSGTAMQAFNKQLSATEIAAVVTYERNAWGNNTG
CCCHHHCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHCCHHEEEEEEEEECCCCCCCCC
DTVQASDVNGHGSDSTPTAQTGMQETDQAPPASAAETSTEAPPAAESTADEPSADEPMSM
CEEEECCCCCCCCCCCCCHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
DALMARGEQVYMASCAACHQANGAGLPGAFPAIKGSPIATGPIANHLDIVIHGKAGTAMQ
HHHHHCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHH
AFGSMLSARDIAAVVTYERNAWDNNTGDSVQATDVNNHGK
HHHHHHHHCCEEEEEEEECCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MKQWLYCFAAALLAPPIFAADMPLNMTQGVTEISGKVYGLHMTILYICCAIGVVVFGAMI
CCHHHHHHHHHHHCCCCEECCCCCCHHCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHH
YAMINHRKSKGAVAAQFHESTKVEIAWTLVPFLILIAMAIPATKTLIAMEDPSNADLTIK
HHHHHCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
ITGSQWKWHYDYFDHDFGFYSILATPRSQIEGAEAKGDHYLLEVDKHLVLPTNRKVRFLM
EECCCEEEEECCCCCCCCEEEEEECCHHHCCCCCCCCCEEEEEECCEEECCCCCCEEEEE
TSDDVIHSWWVPAFAVKKDANPGFINEAWTRIDKPGIYHGQCAELCGKDHGFMPIVVEVL
ECCCHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCCCCEEHEECC
PEAEFDTWVENQKQLASNAAAEAAAALNQTLSMEELMVQGEKVYMASCAACHQPNGMGLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEHHHHHCCCCCCCCC
GVFPALKGSAIAMGPVDKHLDIVINGKSGTAMQAFNKQLSATEIAAVVTYERNAWGNNTG
CCCHHHCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHCCHHEEEEEEEEECCCCCCCCC
DTVQASDVNGHGSDSTPTAQTGMQETDQAPPASAAETSTEAPPAAESTADEPSADEPMSM
CEEEECCCCCCCCCCCCCHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
DALMARGEQVYMASCAACHQANGAGLPGAFPAIKGSPIATGPIANHLDIVIHGKAGTAMQ
HHHHHCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHH
AFGSMLSARDIAAVVTYERNAWDNNTGDSVQATDVNNHGK
HHHHHHHHCCEEEEEEEECCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA