Click here to switch to the map view.

The map label for this gene is cusB [H]

Identifier: 119776606

GI number: 119776606

Start: 4102477

End: 4104057

Strand: Direct

Name: cusB [H]

Synonym: Sama_3474

Alternate gene names: 119776606

Gene position: 4102477-4104057 (Clockwise)

Preceding gene: 119776605

Following gene: 119776607

Centisome position: 95.27

GC content: 56.04

Gene sequence:

>1581_bases
ATGAACACGAAAAAGCAAAAAAGTGCCCTGCTGCTGATGGGTGCCAGTCTGGCATTCGGTCCCGGCATGCCTGCCATGGT
ATTGGCTGAAAGCCCACAGCAGTCTCCCGCATCGGAGGCCGCAGCAGCCGCCGTTTATCACTGCCCCATGCATCCCGAGG
TAGAAAGCCACGAGCCGGGGCGCTGTCCCAAGTGCAAGATGTTTCTGGTACCCGGTGCAGGCATCTCTGGCCAGTCCAGC
GAGCCCTTGGCTGAGGCGCACAAGACCTATATTTGCCCCATGCATCCCGAAGTGGAAAGTCATGAACCCGGCCGTTGTCC
CAAGTGCAACATGTTCCTCGTTGAAAAAGAAGAGGAAGAAGAGGCTGACCCTCAGCCAGAGCATAAGTCGACGGAAGATC
ACAGCGCCCATCTGGCCGCACAAAACGATATTTTCGCCACCCCTGCAGCCAGTCCAATCGACGGTGGCAAGGTCAAATAT
GTGTGCCCCATGCACGCCCATATCATCAGCGATGAGCCCGGCACCTGCCCCATCTGCGGTATGGACCTCGAGAAGGTAGA
ACTCGGCGGGGGCCAGGAGGTTCTGGTCGACGTATCCGGTGGCATGCAGCAGGCACTGGCGCTCAGGGTTGCCAAAGCCG
AACGCCAAACCCTGTGGAAATTTGTCGATACCGTTGGCCAAATCGAATACGACGAGCGCCAAATCCACCATGTGCACGCC
CGCCTGAACGGTTGGATTGAAACCCTCAAGGTCAATGCCGTTGGTGACAAAGTCAGTAAAGGGCAATTGCTGTACGAAAT
CTATTCGCCGGATCTGGTTAACGCTCAGGATGACTATCTGCTTGCACTGGATACCGTTAAAAAATCCGGTGATTCAGGTC
GTTACAAAGAGTTGCTGCGAAAAGCCAGTCTGCGACTTGAACTGCTCGGCATGAATGAGGCGCAAATCAAAGAGCTTGCC
AAAACCCAAACGACCCAATATCGGGTGCCCTTCTACGCCCGCCAGGATGGGGTGATCACCACCCTGAATACCCGTGAAGG
CATGTACATTCAACCCATGAGCGAAGTGCTCGCCCTGACAGACATCAGCAAGGTATGGGTCATAGCCGACGTATTCGAAA
ATGAGCAGAGCTGGCTCAAAGTAGGTCAGCCCGCCGAAGTGGCGGTACCTGCCATGGGGCTCAGCGGCATCAAAGGCACC
ATAGATTATATTTATCCCGAGCTGGACCCTGTCACCCGCAGCCTGCGGGTACGGGTAGTGCTGGACAACCCAAACCAACA
GCTGCGCCCCAATACGCTCGCCAAGGTCAAACTTTATGGCGGGCCCGAGCGAGACGTTCTGACCATTCCCCAGGAAGCGT
TGATTCAAACGGGTAAGGAAAACAGGGTGATAGTTCGCACCGCAGATAACAGCTTTGCCGCCCGCCAGGTCACTGTCGGC
ATGTATTCCCAGGGCAAGGTTGAGGTGCTGTCTGGTCTGAGTGACGGTGAAGAAGTCGTGACATCCGGGCAGTTTTTGCT
GGACTCCGAAGCCAGTCTCAAGGGCAGCCTGATGCGCCTTGGCAGCGGCCATCAGCACTAA

Upstream 100 bases:

>100_bases
GAGCCGGTTGCCGCCAAGGGCGAGCACTGCGCCAACTGTCCTAAAAAAGCCATGAACCATCAGCATCACTGACAGGCCAA
GGGTGGAAATGAGGTTTACT

Downstream 100 bases:

>100_bases
GGAGGCCTTATGTTGGATTACATTATCAAGTCTTCTATCCGCCAGCGATTTATGGTGCTGGTGGTGGCGCTGATGGTGAC
CCTTTGGGGCATTACAGAAC

Product: heavy metal efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MNTKKQKSALLLMGASLAFGPGMPAMVLAESPQQSPASEAAAAAVYHCPMHPEVESHEPGRCPKCKMFLVPGAGISGQSS
EPLAEAHKTYICPMHPEVESHEPGRCPKCNMFLVEKEEEEEADPQPEHKSTEDHSAHLAAQNDIFATPAASPIDGGKVKY
VCPMHAHIISDEPGTCPICGMDLEKVELGGGQEVLVDVSGGMQQALALRVAKAERQTLWKFVDTVGQIEYDERQIHHVHA
RLNGWIETLKVNAVGDKVSKGQLLYEIYSPDLVNAQDDYLLALDTVKKSGDSGRYKELLRKASLRLELLGMNEAQIKELA
KTQTTQYRVPFYARQDGVITTLNTREGMYIQPMSEVLALTDISKVWVIADVFENEQSWLKVGQPAEVAVPAMGLSGIKGT
IDYIYPELDPVTRSLRVRVVLDNPNQQLRPNTLAKVKLYGGPERDVLTIPQEALIQTGKENRVIVRTADNSFAARQVTVG
MYSQGKVEVLSGLSDGEEVVTSGQFLLDSEASLKGSLMRLGSGHQH

Sequences:

>Translated_526_residues
MNTKKQKSALLLMGASLAFGPGMPAMVLAESPQQSPASEAAAAAVYHCPMHPEVESHEPGRCPKCKMFLVPGAGISGQSS
EPLAEAHKTYICPMHPEVESHEPGRCPKCNMFLVEKEEEEEADPQPEHKSTEDHSAHLAAQNDIFATPAASPIDGGKVKY
VCPMHAHIISDEPGTCPICGMDLEKVELGGGQEVLVDVSGGMQQALALRVAKAERQTLWKFVDTVGQIEYDERQIHHVHA
RLNGWIETLKVNAVGDKVSKGQLLYEIYSPDLVNAQDDYLLALDTVKKSGDSGRYKELLRKASLRLELLGMNEAQIKELA
KTQTTQYRVPFYARQDGVITTLNTREGMYIQPMSEVLALTDISKVWVIADVFENEQSWLKVGQPAEVAVPAMGLSGIKGT
IDYIYPELDPVTRSLRVRVVLDNPNQQLRPNTLAKVKLYGGPERDVLTIPQEALIQTGKENRVIVRTADNSFAARQVTVG
MYSQGKVEVLSGLSDGEEVVTSGQFLLDSEASLKGSLMRLGSGHQH
>Mature_526_residues
MNTKKQKSALLLMGASLAFGPGMPAMVLAESPQQSPASEAAAAAVYHCPMHPEVESHEPGRCPKCKMFLVPGAGISGQSS
EPLAEAHKTYICPMHPEVESHEPGRCPKCNMFLVEKEEEEEADPQPEHKSTEDHSAHLAAQNDIFATPAASPIDGGKVKY
VCPMHAHIISDEPGTCPICGMDLEKVELGGGQEVLVDVSGGMQQALALRVAKAERQTLWKFVDTVGQIEYDERQIHHVHA
RLNGWIETLKVNAVGDKVSKGQLLYEIYSPDLVNAQDDYLLALDTVKKSGDSGRYKELLRKASLRLELLGMNEAQIKELA
KTQTTQYRVPFYARQDGVITTLNTREGMYIQPMSEVLALTDISKVWVIADVFENEQSWLKVGQPAEVAVPAMGLSGIKGT
IDYIYPELDPVTRSLRVRVVLDNPNQQLRPNTLAKVKLYGGPERDVLTIPQEALIQTGKENRVIVRTADNSFAARQVTVG
MYSQGKVEVLSGLSDGEEVVTSGQFLLDSEASLKGSLMRLGSGHQH

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=376, Percent_Identity=34.5744680851064, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI87081796, Length=301, Percent_Identity=29.2358803986711, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 57555; Mature: 57555

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKKQKSALLLMGASLAFGPGMPAMVLAESPQQSPASEAAAAAVYHCPMHPEVESHEPG
CCCCHHCCEEEEEECCEECCCCCCEEEEECCCCCCCHHHHHHEEEEECCCCCCCCCCCCC
RCPKCKMFLVPGAGISGQSSEPLAEAHKTYICPMHPEVESHEPGRCPKCNMFLVEKEEEE
CCCCEEEEEECCCCCCCCCCCCHHHHCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCC
EADPQPEHKSTEDHSAHLAAQNDIFATPAASPIDGGKVKYVCPMHAHIISDEPGTCPICG
CCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCEEEEECCCEEEEECCCCCCCCEEC
MDLEKVELGGGQEVLVDVSGGMQQALALRVAKAERQTLWKFVDTVGQIEYDERQIHHVHA
CCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RLNGWIETLKVNAVGDKVSKGQLLYEIYSPDLVNAQDDYLLALDTVKKSGDSGRYKELLR
HHHCEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHH
KASLRLELLGMNEAQIKELAKTQTTQYRVPFYARQDGVITTLNTREGMYIQPMSEVLALT
HHCCEEEEECCCHHHHHHHHHHCCCEEECCEEECCCCEEEEEECCCCEEECCHHHHHHHH
DISKVWVIADVFENEQSWLKVGQPAEVAVPAMGLSGIKGTIDYIYPELDPVTRSLRVRVV
CCCCEEEEEEHHCCCHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEE
LDNPNQQLRPNTLAKVKLYGGPERDVLTIPQEALIQTGKENRVIVRTADNSFAARQVTVG
EECCCCCCCCCCEEEEEEECCCCCCEEECCHHHHHHCCCCCEEEEEECCCCCEEEEEEEE
MYSQGKVEVLSGLSDGEEVVTSGQFLLDSEASLKGSLMRLGSGHQH
ECCCCCEEEECCCCCCHHHHHCCCEEEECCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MNTKKQKSALLLMGASLAFGPGMPAMVLAESPQQSPASEAAAAAVYHCPMHPEVESHEPG
CCCCHHCCEEEEEECCEECCCCCCEEEEECCCCCCCHHHHHHEEEEECCCCCCCCCCCCC
RCPKCKMFLVPGAGISGQSSEPLAEAHKTYICPMHPEVESHEPGRCPKCNMFLVEKEEEE
CCCCEEEEEECCCCCCCCCCCCHHHHCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCC
EADPQPEHKSTEDHSAHLAAQNDIFATPAASPIDGGKVKYVCPMHAHIISDEPGTCPICG
CCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCEEEEECCCEEEEECCCCCCCCEEC
MDLEKVELGGGQEVLVDVSGGMQQALALRVAKAERQTLWKFVDTVGQIEYDERQIHHVHA
CCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RLNGWIETLKVNAVGDKVSKGQLLYEIYSPDLVNAQDDYLLALDTVKKSGDSGRYKELLR
HHHCEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHH
KASLRLELLGMNEAQIKELAKTQTTQYRVPFYARQDGVITTLNTREGMYIQPMSEVLALT
HHCCEEEEECCCHHHHHHHHHHCCCEEECCEEECCCCEEEEEECCCCEEECCHHHHHHHH
DISKVWVIADVFENEQSWLKVGQPAEVAVPAMGLSGIKGTIDYIYPELDPVTRSLRVRVV
CCCCEEEEEEHHCCCHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEE
LDNPNQQLRPNTLAKVKLYGGPERDVLTIPQEALIQTGKENRVIVRTADNSFAARQVTVG
EECCCCCCCCCCEEEEEEECCCCCCEEECCHHHHHHCCCCCEEEEEECCCCCEEEEEEEE
MYSQGKVEVLSGLSDGEEVVTSGQFLLDSEASLKGSLMRLGSGHQH
ECCCCCEEEECCCCCCHHHHHCCCEEEECCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]