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The map label for this gene is nahR [H]

Identifier: 119776581

GI number: 119776581

Start: 4079887

End: 4080867

Strand: Direct

Name: nahR [H]

Synonym: Sama_3449

Alternate gene names: 119776581

Gene position: 4079887-4080867 (Clockwise)

Preceding gene: 119776572

Following gene: 119776582

Centisome position: 94.75

GC content: 56.57

Gene sequence:

>981_bases
ATGCAACTGGACAAGCTGACACGCATCGATCTGAATTTGTTGGTGGTACTGCAGGTACTGCTGGAAGAACAAAGTGTCAC
CCGCGCTGCTGTGCGCCTGAATCTCAGCCAGTCAGCCCTGTCCAAGAGCCTGAGCCGACTGAGGGAAACCCTGGGCGATC
CGCTGTTTTCCCGTACGGCCCACGGGCTGAAACCCACGGCCCACGCACTGGCATTGGCCGAGCGACTGCCTGGAGTATTG
CAGGCGCTGAATCAGCTGGTGATGCCACCCAGTTTTGATCCCGCCAGCAGTACCCGCACCTTCAGTTTTGCCATGGTAGA
AAGCGCGTACGAGACGTTGATCCCCGGCTTTATCGGCCCCCTCTTGTCCATGGCGCCGGGTCTGCGACTCAATTCCTACG
TGTGGAACGAAAAATCCATCAGCGATCTGCAGCTGGGGCAGATTGATTTTGGGATAGACGGTATCGATTTGCAGCCCGAA
GCCAACTTTCGTATCGACAGCCTGCCGGAAGGCATTTGCCATCAGACACTCTATCAGGACCAACAAATTTGTTTGGTACG
CAAGGGCCACCCGGCCATAGCGCTGCTTGGGGAAGGAAAGTGGGACCTCAGCCGCTACCTGGAGTTGGCTCATGTGCAGG
TACGCTGCGAAGGTAACGATTGGTGGGCGTTGGATTACTATTTGGCGACCCAGGGTAAGCAGCGGCACCTATGCGCTACC
GTGCCCGACTTTTATGGCGCCGCCAGCGTGTGCGCCAATACCGACCTGGTGTTCACCCTGCCTCAGAGCTTTGCGCGCCA
TGCCTCCAAACTCTACGCCTTGGAGATGCTGCCACTCCCCTTTGACTTTATGCCCCTGGCCTATGTGCTCTTGTGGCATC
AACGAAATGACGGCGATCCCGGCCACAGATGGATACGCGAGCTTATCACCCAAAGCGCCCGTAAAAGCTTTGGTGACAAA
CTCAAATGGACGCAAGATTAA

Upstream 100 bases:

>100_bases
ACAGGTTGGTAAAGAAAAATTATAGATGAAGTTTACTCCTGCCATGGTATGAACAGAAATGGTATAAATTACTTTTAAAA
ATTCCCCTTTGGAATATCAC

Downstream 100 bases:

>100_bases
CCATATTTCACGTGATTATGGTGCACATTTTACGCAGACTGTCAGCACGACATTCGCCCAGGAGGCATTATGATCTACAG
TCAATTCCACACTCCCCCCT

Product: regulatory protein, LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MQLDKLTRIDLNLLVVLQVLLEEQSVTRAAVRLNLSQSALSKSLSRLRETLGDPLFSRTAHGLKPTAHALALAERLPGVL
QALNQLVMPPSFDPASSTRTFSFAMVESAYETLIPGFIGPLLSMAPGLRLNSYVWNEKSISDLQLGQIDFGIDGIDLQPE
ANFRIDSLPEGICHQTLYQDQQICLVRKGHPAIALLGEGKWDLSRYLELAHVQVRCEGNDWWALDYYLATQGKQRHLCAT
VPDFYGAASVCANTDLVFTLPQSFARHASKLYALEMLPLPFDFMPLAYVLLWHQRNDGDPGHRWIRELITQSARKSFGDK
LKWTQD

Sequences:

>Translated_326_residues
MQLDKLTRIDLNLLVVLQVLLEEQSVTRAAVRLNLSQSALSKSLSRLRETLGDPLFSRTAHGLKPTAHALALAERLPGVL
QALNQLVMPPSFDPASSTRTFSFAMVESAYETLIPGFIGPLLSMAPGLRLNSYVWNEKSISDLQLGQIDFGIDGIDLQPE
ANFRIDSLPEGICHQTLYQDQQICLVRKGHPAIALLGEGKWDLSRYLELAHVQVRCEGNDWWALDYYLATQGKQRHLCAT
VPDFYGAASVCANTDLVFTLPQSFARHASKLYALEMLPLPFDFMPLAYVLLWHQRNDGDPGHRWIRELITQSARKSFGDK
LKWTQD
>Mature_326_residues
MQLDKLTRIDLNLLVVLQVLLEEQSVTRAAVRLNLSQSALSKSLSRLRETLGDPLFSRTAHGLKPTAHALALAERLPGVL
QALNQLVMPPSFDPASSTRTFSFAMVESAYETLIPGFIGPLLSMAPGLRLNSYVWNEKSISDLQLGQIDFGIDGIDLQPE
ANFRIDSLPEGICHQTLYQDQQICLVRKGHPAIALLGEGKWDLSRYLELAHVQVRCEGNDWWALDYYLATQGKQRHLCAT
VPDFYGAASVCANTDLVFTLPQSFARHASKLYALEMLPLPFDFMPLAYVLLWHQRNDGDPGHRWIRELITQSARKSFGDK
LKWTQD

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=29.8657718120805, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87081684, Length=315, Percent_Identity=26.984126984127, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081766, Length=279, Percent_Identity=27.9569892473118, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786820, Length=82, Percent_Identity=40.2439024390244, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36600; Mature: 36600

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLDKLTRIDLNLLVVLQVLLEEQSVTRAAVRLNLSQSALSKSLSRLRETLGDPLFSRTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHC
HGLKPTAHALALAERLPGVLQALNQLVMPPSFDPASSTRTFSFAMVESAYETLIPGFIGP
CCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
LLSMAPGLRLNSYVWNEKSISDLQLGQIDFGIDGIDLQPEANFRIDSLPEGICHQTLYQD
HHHHCCCCEECCEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
QQICLVRKGHPAIALLGEGKWDLSRYLELAHVQVRCEGNDWWALDYYLATQGKQRHLCAT
CCEEEEECCCCEEEEEECCCHHHHHHHHHHEEEEEECCCCEEEEEEEEECCCCCCCEEEC
VPDFYGAASVCANTDLVFTLPQSFARHASKLYALEMLPLPFDFMPLAYVLLWHQRNDGDP
CCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCH
GHRWIRELITQSARKSFGDKLKWTQD
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQLDKLTRIDLNLLVVLQVLLEEQSVTRAAVRLNLSQSALSKSLSRLRETLGDPLFSRTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHC
HGLKPTAHALALAERLPGVLQALNQLVMPPSFDPASSTRTFSFAMVESAYETLIPGFIGP
CCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
LLSMAPGLRLNSYVWNEKSISDLQLGQIDFGIDGIDLQPEANFRIDSLPEGICHQTLYQD
HHHHCCCCEECCEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
QQICLVRKGHPAIALLGEGKWDLSRYLELAHVQVRCEGNDWWALDYYLATQGKQRHLCAT
CCEEEEECCCCEEEEEECCCHHHHHHHHHHEEEEEECCCCEEEEEEEEECCCCCCCEEEC
VPDFYGAASVCANTDLVFTLPQSFARHASKLYALEMLPLPFDFMPLAYVLLWHQRNDGDP
CCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCH
GHRWIRELITQSARKSFGDKLKWTQD
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]