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The map label for this gene is fabF [H]

Identifier: 119776523

GI number: 119776523

Start: 4019353

End: 4020558

Strand: Direct

Name: fabF [H]

Synonym: Sama_3391

Alternate gene names: 119776523

Gene position: 4019353-4020558 (Clockwise)

Preceding gene: 119776522

Following gene: 119776524

Centisome position: 93.34

GC content: 59.78

Gene sequence:

>1206_bases
GTGACCCAGATAGCCATCACAGACACAGGTTTATGCACTCCCATTGGGATGAGTGCAGCCGAGATCCTGCCTCGCCTCCT
CGCGGGAGACACCAGTGGTATGGTGCTGCGTGCCGATCTGCTGGCAACTGGCCCCACCCTGGTGGGCGAAGTGGCGCAAG
ACTTACCACAACTGCCCGACGCCATGGCGCAGTTTGACTGTCGCAACAACCAATTGCTGCTGGCTGCTGCCATACAAATC
GCCCCCACGGTTGTCCAGGCTATCGCCAGTTTTGGCAAAGATCGCATCGGCGTTGTGCTCGGCACCTCCACCTCCGGCAT
TGCCAAGGGCGAAGAAGCCCTGGCCTACCGGGCCGAGCACGGTAAATTCCCCGCCGATTATCATTACTTCCAGCAGGAGC
TTGGCAGCACCAGCGACTTTTTACGTCAGTACTTTGAACTCGATGGTCCCTGCTACACACTCTCTACCGCCTGCTCATCC
AGCGCCAAGGTATTTGCCAGCGCCAAGCGATTACTCAATGCCAATTTGTGCGACATGGTGATTGTGGGCGGCGTCGACAG
CCTATGTCGCCTTACGGTCAATGGCTTCGATGCGCTGGAGTCGGTGTCCAAAGGCCACTGCAATCCCTTCAGCGCCAATC
GCGATGGCATCAACATTGGTGAGGGCGCAGCGCTCTTTACCCTGGTGCGCGGCGACGGCCCAGTGCTGCTCAGTGGCTGC
GGCGAGTCCGGCGATGCCCACCATATCTCGGCGCCGCACCCCGAAGGACGCGGCGCTATCGACGCCATGGGCGCAGCGCT
CAAAGACGCAGGCCTAAAGCCCGCCGACATCGATTACATTAACCTGCACGGCACCGCCACGCCGAAAAACGATGCCATGG
AGAGCCGCGCGGTTTGTGCCGTATTTGAAGGCCATTTGCCTCCCTGCAGTTCCACCAAGCCGCTCACCGGCCACGCCCTC
GGTGCCGCAGGTGCTATCGAAGCCGCCTTTTGTGTATTGCTGCTGAGCGAAGGCAATCGCGCTCTGCCGCCTCAGGTGTG
GGATGGCATCGCCGACACCAACGACCCGCAATTACCTCTGGTTCCCATGCCGCATACGCAAGATCCCGGCAACGGTCACG
ATATCCGTCATGTGATGAGCAATTCTTTCGCCTTTGGCGGCAGTAACGCCAGTTTGATTTTCAGCCGTGGAGGCCAGCAT
GACTGA

Upstream 100 bases:

>100_bases
AATACTGGAAATGCCTTCAGCCGGGATGAAGCTGAAAATTACGCCGCTTGCTTGACCAGGACAGGGGCATTTTCAGCTGT
AAAGTTTAGGAAGAAACACA

Downstream 100 bases:

>100_bases
CAAACTCTGGGATGGCGCGCCGCTTTCCAGCATTGACGTTGAAACCTTTTTGCCCCATCGCCGCCCCATGGTGCTGATTG
ACGAGGTGCTGGAGCACGGC

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTQIAITDTGLCTPIGMSAAEILPRLLAGDTSGMVLRADLLATGPTLVGEVAQDLPQLPDAMAQFDCRNNQLLLAAAIQI
APTVVQAIASFGKDRIGVVLGTSTSGIAKGEEALAYRAEHGKFPADYHYFQQELGSTSDFLRQYFELDGPCYTLSTACSS
SAKVFASAKRLLNANLCDMVIVGGVDSLCRLTVNGFDALESVSKGHCNPFSANRDGINIGEGAALFTLVRGDGPVLLSGC
GESGDAHHISAPHPEGRGAIDAMGAALKDAGLKPADIDYINLHGTATPKNDAMESRAVCAVFEGHLPPCSSTKPLTGHAL
GAAGAIEAAFCVLLLSEGNRALPPQVWDGIADTNDPQLPLVPMPHTQDPGNGHDIRHVMSNSFAFGGSNASLIFSRGGQH
D

Sequences:

>Translated_401_residues
MTQIAITDTGLCTPIGMSAAEILPRLLAGDTSGMVLRADLLATGPTLVGEVAQDLPQLPDAMAQFDCRNNQLLLAAAIQI
APTVVQAIASFGKDRIGVVLGTSTSGIAKGEEALAYRAEHGKFPADYHYFQQELGSTSDFLRQYFELDGPCYTLSTACSS
SAKVFASAKRLLNANLCDMVIVGGVDSLCRLTVNGFDALESVSKGHCNPFSANRDGINIGEGAALFTLVRGDGPVLLSGC
GESGDAHHISAPHPEGRGAIDAMGAALKDAGLKPADIDYINLHGTATPKNDAMESRAVCAVFEGHLPPCSSTKPLTGHAL
GAAGAIEAAFCVLLLSEGNRALPPQVWDGIADTNDPQLPLVPMPHTQDPGNGHDIRHVMSNSFAFGGSNASLIFSRGGQH
D
>Mature_400_residues
TQIAITDTGLCTPIGMSAAEILPRLLAGDTSGMVLRADLLATGPTLVGEVAQDLPQLPDAMAQFDCRNNQLLLAAAIQIA
PTVVQAIASFGKDRIGVVLGTSTSGIAKGEEALAYRAEHGKFPADYHYFQQELGSTSDFLRQYFELDGPCYTLSTACSSS
AKVFASAKRLLNANLCDMVIVGGVDSLCRLTVNGFDALESVSKGHCNPFSANRDGINIGEGAALFTLVRGDGPVLLSGCG
ESGDAHHISAPHPEGRGAIDAMGAALKDAGLKPADIDYINLHGTATPKNDAMESRAVCAVFEGHLPPCSSTKPLTGHALG
AAGAIEAAFCVLLLSEGNRALPPQVWDGIADTNDPQLPLVPMPHTQDPGNGHDIRHVMSNSFAFGGSNASLIFSRGGQHD

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=421, Percent_Identity=31.8289786223278, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI223972627, Length=151, Percent_Identity=45.6953642384106, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI41872631, Length=269, Percent_Identity=28.996282527881, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787337, Length=269, Percent_Identity=35.6877323420074, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788663, Length=424, Percent_Identity=29.4811320754717, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71983541, Length=271, Percent_Identity=30.2583025830258, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=31.0606060606061, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=284, Percent_Identity=28.8732394366197, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=270, Percent_Identity=31.1111111111111, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644341, Length=420, Percent_Identity=30.7142857142857, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41732; Mature: 41600

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIAITDTGLCTPIGMSAAEILPRLLAGDTSGMVLRADLLATGPTLVGEVAQDLPQLPD
CCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHH
AMAQFDCRNNQLLLAAAIQIAPTVVQAIASFGKDRIGVVLGTSTSGIAKGEEALAYRAEH
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHC
GKFPADYHYFQQELGSTSDFLRQYFELDGPCYTLSTACSSSAKVFASAKRLLNANLCDMV
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHCCHHHHHHHHHHHHCCCCHHEE
IVGGVDSLCRLTVNGFDALESVSKGHCNPFSANRDGINIGEGAALFTLVRGDGPVLLSGC
EECCCCHHHHEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECC
GESGDAHHISAPHPEGRGAIDAMGAALKDAGLKPADIDYINLHGTATPKNDAMESRAVCA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHEEE
VFEGHLPPCSSTKPLTGHALGAAGAIEAAFCVLLLSEGNRALPPQVWDGIADTNDPQLPL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCE
VPMPHTQDPGNGHDIRHVMSNSFAFGGSNASLIFSRGGQHD
ECCCCCCCCCCCHHHHHHHHCCCEECCCCCEEEEECCCCCC
>Mature Secondary Structure 
TQIAITDTGLCTPIGMSAAEILPRLLAGDTSGMVLRADLLATGPTLVGEVAQDLPQLPD
CEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHH
AMAQFDCRNNQLLLAAAIQIAPTVVQAIASFGKDRIGVVLGTSTSGIAKGEEALAYRAEH
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHC
GKFPADYHYFQQELGSTSDFLRQYFELDGPCYTLSTACSSSAKVFASAKRLLNANLCDMV
CCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEHHHHCCHHHHHHHHHHHHCCCCHHEE
IVGGVDSLCRLTVNGFDALESVSKGHCNPFSANRDGINIGEGAALFTLVRGDGPVLLSGC
EECCCCHHHHEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECC
GESGDAHHISAPHPEGRGAIDAMGAALKDAGLKPADIDYINLHGTATPKNDAMESRAVCA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHEEE
VFEGHLPPCSSTKPLTGHALGAAGAIEAAFCVLLLSEGNRALPPQVWDGIADTNDPQLPL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCE
VPMPHTQDPGNGHDIRHVMSNSFAFGGSNASLIFSRGGQHD
ECCCCCCCCCCCHHHHHHHHCCCEECCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]