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The map label for this gene is aroB

Identifier: 119776499

GI number: 119776499

Start: 3993164

End: 3994243

Strand: Reverse

Name: aroB

Synonym: Sama_3367

Alternate gene names: 119776499

Gene position: 3994243-3993164 (Counterclockwise)

Preceding gene: 119776500

Following gene: 119776498

Centisome position: 92.76

GC content: 49.81

Gene sequence:

>1080_bases
ATGAAGCAAATTCAGGTTGATTTGGCAAATCGAAGTTATCCGATCCACATTGGCCCGAATTTGTTTGAAGATCAGGAGCT
CTTTGCGCCTGTGGTGAGTGGCAAAAAAGTACTCGTTGTCAGTAACGAGACGATTGCTCCCCTCTATCTCGATAAGATCA
GTGCCACCCTGTCCGCTCGCGCGGCTCAGGTGGCTTCTGTGATCCTGCCTGACGGCGAGCAATACAAAACACTCGACTAT
CTCAATGAGATTTTTGACGCTCTGCTTGAAGGAAATTTTGCCCGCGATTGTGTTCTGGTTGCACTCGGTGGTGGTGTGAT
TGGCGATATGACCGGGTTTGCTGCGGCCTGTTATCAACGCGGTGTTGATTTTATTCAAATTCCTACCACGCTGTTATCCC
AGGTCGACTCCTCTGTGGGTGGCAAAACTGCTGTGAACCATCCTTTGGGTAAAAACATGATAGGAGCCTTCTATCAACCC
AAATTGGTGGTCATTGATATTAATTGCCTGAAAACTCTGCCAGCCAGAGAGTTTGCAGCCGGTATGGCAGAGGTGATTAA
GTACGGCATTATTCGTGACAGTGAACTCTTTACCTGGTTGGAACAAAACGTTTCAGCGCTTAAAGCACTGGACCAGGATG
CCATTATCCACGTTATTGCCCGCTGCTGCGAAATCAAAGCCGAGGTAGTATCAGAAGATGAAACAGAGCAGGGCGTTCGC
GCTTTGCTCAATCTGGGACACACCTTTGGTCATGCCATTGAAGCCGAAATGGGCTATGGCAATTGGCTGCATGGCGAAGC
TGTTGCCGCTGGCATGGTACTTGCTGCACAAACTTCGGTAACACTGGGGCTAATCGATAAGTCAATTCTTTGTCGTATTG
CGGCACTTATTCAGGCATTCGATTTGCCCGTCCAGGCTCCGGAGTCCATGGACTTTAATAGCTTTATTAAGCATATGCGG
CGAGATAAAAAGGTATTGGGTGGCCAGCTCAGGTTGGTTTTGCCGTTGGGCATTGGCGCCGCTGAAGTCAGCAGCCAGGC
CTCTGATGCCGAGCTGGCAGAGGTCATTCGCCGCCCCTGA

Upstream 100 bases:

>100_bases
ACTCTATGAAGAAATCGCTGATGTGATTGTCAAAACCGATGACCAAAGTGCCAAGGTCGTTGCCAATCAAATCATCGAAC
AGCTGGGATTCTGACGCACC

Downstream 100 bases:

>100_bases
CATCGGGTGCAACATGACATTTATTCCTCCTTCAGTACTGCTTCCCTCTCAAGAGGCCCTGCTGCTTCGAATGCAGCATG
TTGCTAGCTATAGCCAGCAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKQIQVDLANRSYPIHIGPNLFEDQELFAPVVSGKKVLVVSNETIAPLYLDKISATLSARAAQVASVILPDGEQYKTLDY
LNEIFDALLEGNFARDCVLVALGGGVIGDMTGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KLVVIDINCLKTLPAREFAAGMAEVIKYGIIRDSELFTWLEQNVSALKALDQDAIIHVIARCCEIKAEVVSEDETEQGVR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVLAAQTSVTLGLIDKSILCRIAALIQAFDLPVQAPESMDFNSFIKHMR
RDKKVLGGQLRLVLPLGIGAAEVSSQASDAELAEVIRRP

Sequences:

>Translated_359_residues
MKQIQVDLANRSYPIHIGPNLFEDQELFAPVVSGKKVLVVSNETIAPLYLDKISATLSARAAQVASVILPDGEQYKTLDY
LNEIFDALLEGNFARDCVLVALGGGVIGDMTGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KLVVIDINCLKTLPAREFAAGMAEVIKYGIIRDSELFTWLEQNVSALKALDQDAIIHVIARCCEIKAEVVSEDETEQGVR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVLAAQTSVTLGLIDKSILCRIAALIQAFDLPVQAPESMDFNSFIKHMR
RDKKVLGGQLRLVLPLGIGAAEVSSQASDAELAEVIRRP
>Mature_359_residues
MKQIQVDLANRSYPIHIGPNLFEDQELFAPVVSGKKVLVVSNETIAPLYLDKISATLSARAAQVASVILPDGEQYKTLDY
LNEIFDALLEGNFARDCVLVALGGGVIGDMTGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KLVVIDINCLKTLPAREFAAGMAEVIKYGIIRDSELFTWLEQNVSALKALDQDAIIHVIARCCEIKAEVVSEDETEQGVR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVLAAQTSVTLGLIDKSILCRIAALIQAFDLPVQAPESMDFNSFIKHMR
RDKKVLGGQLRLVLPLGIGAAEVSSQASDAELAEVIRRP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=348, Percent_Identity=63.5057471264368, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6320332, Length=371, Percent_Identity=37.1967654986523, Blast_Score=209, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_SHEAM (A1SB13)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929239.1
- ProteinModelPortal:   A1SB13
- SMR:   A1SB13
- STRING:   A1SB13
- GeneID:   4605614
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3367
- NMPDR:   fig|326297.7.peg.3169
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   A1SB13
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38747; Mature: 38747

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIQVDLANRSYPIHIGPNLFEDQELFAPVVSGKKVLVVSNETIAPLYLDKISATLSAR
CCEEEEEECCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
AAQVASVILPDGEQYKTLDYLNEIFDALLEGNFARDCVLVALGGGVIGDMTGFAAACYQR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKLVVIDINCLKTLPAREFAA
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEECHHHHCCCHHHHHH
GMAEVIKYGIIRDSELFTWLEQNVSALKALDQDAIIHVIARCCEIKAEVVSEDETEQGVR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVLAAQTSVTLGLIDKSILCRIAALIQAF
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLPVQAPESMDFNSFIKHMRRDKKVLGGQLRLVLPLGIGAAEVSSQASDAELAEVIRRP
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKQIQVDLANRSYPIHIGPNLFEDQELFAPVVSGKKVLVVSNETIAPLYLDKISATLSAR
CCEEEEEECCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
AAQVASVILPDGEQYKTLDYLNEIFDALLEGNFARDCVLVALGGGVIGDMTGFAAACYQR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKLVVIDINCLKTLPAREFAA
CCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEECHHHHCCCHHHHHH
GMAEVIKYGIIRDSELFTWLEQNVSALKALDQDAIIHVIARCCEIKAEVVSEDETEQGVR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVLAAQTSVTLGLIDKSILCRIAALIQAF
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLPVQAPESMDFNSFIKHMRRDKKVLGGQLRLVLPLGIGAAEVSSQASDAELAEVIRRP
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA