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The map label for this gene is gph [C]

Identifier: 119776493

GI number: 119776493

Start: 3988559

End: 3989242

Strand: Reverse

Name: gph [C]

Synonym: Sama_3361

Alternate gene names: 119776493

Gene position: 3989242-3988559 (Counterclockwise)

Preceding gene: 119776494

Following gene: 119776492

Centisome position: 92.64

GC content: 55.12

Gene sequence:

>684_bases
ATGACACTGATGAATCGTATCCGTGCCATTGCTTTTGATTTGGATGGCACCTTGGTTGACAGTGTGCCGGATCTCGCCGC
GGCCACCAATGACACTCTTCGCGAGCTGAATTTGCCCCAGTGCACCGAAGCCGAAGTGCGGACATGGGTGGGGAATGGAG
CCAGGGTCTTGATGGCTCGTGCCCTGACCCATGCACTCGGGCGCGATGTGACCGGCTCTATGCTCGACGATGCCATGCCG
CTCTTTATGCGCCATTATGAACGCCATTTGGAGTGTCACAGCCGTTTGTATGATGGGGTTATCGAGACACTCAACGAGCT
TGCTGCCATGGGGATCCGCATGGCTATCGTTACCAATAAACCCCACAGATTCACCCTGCCATTGCTCAGGGCGTTTGGCA
TCGATGACCATTTTGAGCTGGTGCTCGGTGGTGATTCGCTGGAACGAATGAAACCTGATCCCCTGCCGTTGACTCACATT
TTGGACAGCTGGCAGCTCGGCCGTGACGAACTCCTGATGGTGGGCGACAGCCGCAACGATATACTGGCCGCCAAAGCGGC
TGGAATTGCATCCTTTGGCTTGACCTACGGCTACAACTACGGTGAAGATATTGGGCTTTCTGGCCCAGACGCCGTATGTA
ACACCTTTGCAGATATCTTGACTCGCCTGACGGCGACACACTAA

Upstream 100 bases:

>100_bases
GTGCCGACATGTTTGTGGCAGGCAGTGCCATATTTGGCAAACCGGATTACAAGGCCGTTGTTGACCGCATGCGTGCGGAG
CTGGCCAAGGTAGCTGGCTG

Downstream 100 bases:

>100_bases
CGGAGTAAGTACATGACTAAACCCATCGTTCTCAGCGGCGCGCAGCCATCAGGCGAGTTGACCATAGGCAACTACATGGG
TGCACTGCGTCAGTGGGTGG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTLMNRIRAIAFDLDGTLVDSVPDLAAATNDTLRELNLPQCTEAEVRTWVGNGARVLMARALTHALGRDVTGSMLDDAMP
LFMRHYERHLECHSRLYDGVIETLNELAAMGIRMAIVTNKPHRFTLPLLRAFGIDDHFELVLGGDSLERMKPDPLPLTHI
LDSWQLGRDELLMVGDSRNDILAAKAAGIASFGLTYGYNYGEDIGLSGPDAVCNTFADILTRLTATH

Sequences:

>Translated_227_residues
MTLMNRIRAIAFDLDGTLVDSVPDLAAATNDTLRELNLPQCTEAEVRTWVGNGARVLMARALTHALGRDVTGSMLDDAMP
LFMRHYERHLECHSRLYDGVIETLNELAAMGIRMAIVTNKPHRFTLPLLRAFGIDDHFELVLGGDSLERMKPDPLPLTHI
LDSWQLGRDELLMVGDSRNDILAAKAAGIASFGLTYGYNYGEDIGLSGPDAVCNTFADILTRLTATH
>Mature_226_residues
TLMNRIRAIAFDLDGTLVDSVPDLAAATNDTLRELNLPQCTEAEVRTWVGNGARVLMARALTHALGRDVTGSMLDDAMPL
FMRHYERHLECHSRLYDGVIETLNELAAMGIRMAIVTNKPHRFTLPLLRAFGIDDHFELVLGGDSLERMKPDPLPLTHIL
DSWQLGRDELLMVGDSRNDILAAKAAGIASFGLTYGYNYGEDIGLSGPDAVCNTFADILTRLTATH

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=243, Percent_Identity=46.0905349794239, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25021; Mature: 24890

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLMNRIRAIAFDLDGTLVDSVPDLAAATNDTLRELNLPQCTEAEVRTWVGNGARVLMAR
CCHHHHHHHHHHCCCCHHHHCCCHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCHHHHHHH
ALTHALGRDVTGSMLDDAMPLFMRHYERHLECHSRLYDGVIETLNELAAMGIRMAIVTNK
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
PHRFTLPLLRAFGIDDHFELVLGGDSLERMKPDPLPLTHILDSWQLGRDELLMVGDSRND
CCEEHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCC
ILAAKAAGIASFGLTYGYNYGEDIGLSGPDAVCNTFADILTRLTATH
EEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLMNRIRAIAFDLDGTLVDSVPDLAAATNDTLRELNLPQCTEAEVRTWVGNGARVLMAR
CHHHHHHHHHHCCCCHHHHCCCHHHHHCCHHHHHCCCCCCCHHHHHHHHCCCHHHHHHH
ALTHALGRDVTGSMLDDAMPLFMRHYERHLECHSRLYDGVIETLNELAAMGIRMAIVTNK
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
PHRFTLPLLRAFGIDDHFELVLGGDSLERMKPDPLPLTHILDSWQLGRDELLMVGDSRND
CCEEHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCCCC
ILAAKAAGIASFGLTYGYNYGEDIGLSGPDAVCNTFADILTRLTATH
EEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA