Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 119776492

GI number: 119776492

Start: 3987548

End: 3988546

Strand: Reverse

Name: trpS [H]

Synonym: Sama_3360

Alternate gene names: 119776492

Gene position: 3988546-3987548 (Counterclockwise)

Preceding gene: 119776493

Following gene: 119776490

Centisome position: 92.62

GC content: 53.15

Gene sequence:

>999_bases
ATGACTAAACCCATCGTTCTCAGCGGCGCGCAGCCATCAGGCGAGTTGACCATAGGCAACTACATGGGTGCACTGCGTCA
GTGGGTGGCGATGCAGGACAGTCATGATTGTCTTTATTGTGTGGTGGATTTGCATGCCATTACCGTGCGCCAGGATCCCA
AGGCCCTGCGTGAGGCTTGCCTTGACACTCTGGCGCTCTACTTGGCCTGTGGTGTTGACCCGAAAAAGAGCACTGTGTTT
ATCCAGTCTCAGGTGCCACAGCATACTCAGCTTGGCTGGGTGCTCAACTGCTACACCCAGATGGGTGAGCTGTCGCGCAT
GACTCAGTTTAAAGACAAGTCACAAAAGCATGCCAACAATATCAACGTTGGCCTGTTTGGCTACCCTGTACTGATGGCAG
CAGACATTCTTATCTATCAGGCCAATCAAATTCCCGTTGGTCAGGATCAGAAACAGCACCTTGAGCTGACCCGCGATATC
GCGATTCGTTTCAACAACGCCTATGGCGACACCTTTACCGTGCCAGAGCCTTTCATCCCACCCGTGGGTGCCAAGGTGAT
GTCACTGCAGGACCCGACCAAGAAGATGTCCAAGTCAGATGACAATCGCAATAACGTGATTGGTCTGTTGGAAGATCCCA
AGGCGGTATTGAAAAAGCTCAAGAAGGCCATGACCGACAGTGATGAGCCGCCTGTGGTACGTTTCGATGTAGACAACAAA
CCCGGCGTGTCCAACCTGCTTAGCCTGATGTCTGGTGTGACAGGGCAGAGCATCGCTTCGCTGGAAGCCGATTTCGAAGG
CAAGATGTACGGCCATCTTAAGGTAGCCTGTGGCGAAGCCGTTGTTGGCATGCTGGAGCCGCTGCAGGAGCGATATCGTC
AATTCCGTGAAGACAGGGCTTACCTGGATACAGTTATGCGTGACGGCGCCGAGAAGGCCCAGGCGCGTGCCGAAGTAACC
CTGAAACAGGTATACGAAAAAATCGGCCTCTTGGTATAA

Upstream 100 bases:

>100_bases
CTACGGTGAAGATATTGGGCTTTCTGGCCCAGACGCCGTATGTAACACCTTTGCAGATATCTTGACTCGCCTGACGGCGA
CACACTAACGGAGTAAGTAC

Downstream 100 bases:

>100_bases
CGCCAGTCGATTTCGCTAAAAAATCAGCCCACGAGGCTGATTTTTTTATGTCTGCTATCCGGCCATCGCGGCTTGTTGCT
GGATCCATTCGGCAAAGGCG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREACLDTLALYLACGVDPKKSTVF
IQSQVPQHTQLGWVLNCYTQMGELSRMTQFKDKSQKHANNINVGLFGYPVLMAADILIYQANQIPVGQDQKQHLELTRDI
AIRFNNAYGDTFTVPEPFIPPVGAKVMSLQDPTKKMSKSDDNRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDVDNK
PGVSNLLSLMSGVTGQSIASLEADFEGKMYGHLKVACGEAVVGMLEPLQERYRQFREDRAYLDTVMRDGAEKAQARAEVT
LKQVYEKIGLLV

Sequences:

>Translated_332_residues
MTKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREACLDTLALYLACGVDPKKSTVF
IQSQVPQHTQLGWVLNCYTQMGELSRMTQFKDKSQKHANNINVGLFGYPVLMAADILIYQANQIPVGQDQKQHLELTRDI
AIRFNNAYGDTFTVPEPFIPPVGAKVMSLQDPTKKMSKSDDNRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDVDNK
PGVSNLLSLMSGVTGQSIASLEADFEGKMYGHLKVACGEAVVGMLEPLQERYRQFREDRAYLDTVMRDGAEKAQARAEVT
LKQVYEKIGLLV
>Mature_331_residues
TKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREACLDTLALYLACGVDPKKSTVFI
QSQVPQHTQLGWVLNCYTQMGELSRMTQFKDKSQKHANNINVGLFGYPVLMAADILIYQANQIPVGQDQKQHLELTRDIA
IRFNNAYGDTFTVPEPFIPPVGAKVMSLQDPTKKMSKSDDNRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDVDNKP
GVSNLLSLMSGVTGQSIASLEADFEGKMYGHLKVACGEAVVGMLEPLQERYRQFREDRAYLDTVMRDGAEKAQARAEVTL
KQVYEKIGLLV

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=40.785498489426, Blast_Score=274, Evalue=9e-74,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=50.8379888268156, Blast_Score=200, Evalue=2e-51,
Organism=Escherichia coli, GI1789786, Length=331, Percent_Identity=74.0181268882175, Blast_Score=525, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=35.3293413173653, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=35.3293413173653, Blast_Score=200, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6320474, Length=347, Percent_Identity=39.4812680115274, Blast_Score=233, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=40.7294832826748, Blast_Score=251, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36879; Mature: 36748

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREAC
CCCCEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEEEEHEEECCCHHHHHHHH
LDTLALYLACGVDPKKSTVFIQSQVPQHTQLGWVLNCYTQMGELSRMTQFKDKSQKHANN
HHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INVGLFGYPVLMAADILIYQANQIPVGQDQKQHLELTRDIAIRFNNAYGDTFTVPEPFIP
CCEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCC
PVGAKVMSLQDPTKKMSKSDDNRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDVDNK
CCCCCEEECCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
PGVSNLLSLMSGVTGQSIASLEADFEGKMYGHLKVACGEAVVGMLEPLQERYRQFREDRA
CCHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YLDTVMRDGAEKAQARAEVTLKQVYEKIGLLV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREAC
CCCEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEEEEHEEECCCHHHHHHHH
LDTLALYLACGVDPKKSTVFIQSQVPQHTQLGWVLNCYTQMGELSRMTQFKDKSQKHANN
HHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INVGLFGYPVLMAADILIYQANQIPVGQDQKQHLELTRDIAIRFNNAYGDTFTVPEPFIP
CCEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCC
PVGAKVMSLQDPTKKMSKSDDNRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDVDNK
CCCCCEEECCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
PGVSNLLSLMSGVTGQSIASLEADFEGKMYGHLKVACGEAVVGMLEPLQERYRQFREDRA
CCHHHHHHHHHCCCCCHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YLDTVMRDGAEKAQARAEVTLKQVYEKIGLLV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]