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The map label for this gene is uhpC [H]

Identifier: 119776372

GI number: 119776372

Start: 3833455

End: 3834792

Strand: Reverse

Name: uhpC [H]

Synonym: Sama_3240

Alternate gene names: 119776372

Gene position: 3834792-3833455 (Counterclockwise)

Preceding gene: 119776377

Following gene: 119776371

Centisome position: 89.05

GC content: 54.93

Gene sequence:

>1338_bases
ATGCTGGACTTTTTCAAAACGCGGCCGGATCAGCCCCTGATTGAAGGGACACCGGAAAAAATCCGCTCTATTTATAAAAA
ATATCAATGGCAGGTGTTCTTGGGACTGGTGCTGGGTTATGCCATGTTCTACGTCGCCCGCATGAGTTTGAACGTCGCAA
AAAAACCTATGCTGGACGCCGGCATTGTGACCCTGGATGAACTGGGGATCATAGGCTCGGCATTTTTCTTAACCTATGCC
GTGGGTAAGTTCTCCAACGGTTTCCTGTCGGACTACGCCAACATCGGTCGCTTTATGTCGGTGTCGTTGGGTCTGTCGGC
CATCACCTGTTTGTTTATGGGTATGAACACCGCCACCTTCTTCTTCATCCTCTTATGGGCGATGAATGGTTGGTTCCAGT
CGGTGGGCAGTGCGCCTTCGTGCGTGTCGATTTTCCAGTGGTTCTCGCCTAAACAGCGGGGCTCTGTGTACTCCATCTGG
GGCGGCTCTCGCAACATTGGTGAGGGTATCACCTGGATTCTGACTGCCACCGTAGTGAGCTTCTTCGGTTGGAGAGCGGG
CTTTGTGGGTGCCGGTATCGCTACCTTTGCTGCGGCCATCGCCATGTACTTCGTGCTCAAAGACAGACCACAAACCTATG
GTCTGCCAGAGCCAGCCGTTGCCTATGGTGAAGACGCTGAAATCAAGAAGAAGGTTGACCCCAAGGAAATCCGCCGCGCT
CAGCTGTTTATCCTCAAGCAGCCTACCGTGTGGATCATCGCCCTTGCCTGTGCGGCCATGTATATCTCCCGCTATGCCAT
GAGCTCCTGGGCCGTGCTGTATCTGCAGGAAGAAAAGGGCTACAGCCTGATTGATGCGGGCTTTGCCATGTCGGCTTACC
CCATCGCCGGCTTCGCCGGGGCCATTCTGGCCGGGATTATCTCTGACAAGGTGTTTAACGCCAACCGTCACATTCCAACC
CTGCTGTACGGTCTGGCCAACATTGCTGGTCTGTGCCTGATGTTCTGGGGCCCTCAAAGTCGGGTGATGGATGCCGTTGC
CCTGGGTCTGATTGGTTATGCCATCGGTGGTCTGGTGGTGTTCCTGGCCGGTCTTACCGCCTGTGACCTGATGCCCAAGA
CTGCCGTGGGCGCGGTGAAAGGCTTTATCGGCCTGTGCTCCTATATCGCCGCCTCTGCCCAGGAAATCGTGTCTGCCTCG
CTTATCAAAATTCACGAAGTAGACGGCGTGAAACACTACGACTTCTCCACCGCCCAGTACTTCTGGCTGGCCGCTGCCGT
GGTGTCCATGTTCCTCGCCATGAGTGTGTGGAATGCCAAGAAGGTAGTGGATTACTGA

Upstream 100 bases:

>100_bases
GTTTGCTGCTTTTGTGCCCTGCGATTGTGCCTGAAAAGATGCTGGCGAGTCGGGAGCCGGATCCCGGCGAACGAGCAACT
TAAACGTGGGAGGAAGGCAG

Downstream 100 bases:

>100_bases
TAACGGCCGGGCCACCTGCGGGTGGCCCGAAGCAAACCAATCGCGTAAGGAATTTCATTATGTACAAAGCACTTATTGCA
CTGGCACTGCTTGCTCCCGG

Product: putative regulatory protein UhpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MLDFFKTRPDQPLIEGTPEKIRSIYKKYQWQVFLGLVLGYAMFYVARMSLNVAKKPMLDAGIVTLDELGIIGSAFFLTYA
VGKFSNGFLSDYANIGRFMSVSLGLSAITCLFMGMNTATFFFILLWAMNGWFQSVGSAPSCVSIFQWFSPKQRGSVYSIW
GGSRNIGEGITWILTATVVSFFGWRAGFVGAGIATFAAAIAMYFVLKDRPQTYGLPEPAVAYGEDAEIKKKVDPKEIRRA
QLFILKQPTVWIIALACAAMYISRYAMSSWAVLYLQEEKGYSLIDAGFAMSAYPIAGFAGAILAGIISDKVFNANRHIPT
LLYGLANIAGLCLMFWGPQSRVMDAVALGLIGYAIGGLVVFLAGLTACDLMPKTAVGAVKGFIGLCSYIAASAQEIVSAS
LIKIHEVDGVKHYDFSTAQYFWLAAAVVSMFLAMSVWNAKKVVDY

Sequences:

>Translated_445_residues
MLDFFKTRPDQPLIEGTPEKIRSIYKKYQWQVFLGLVLGYAMFYVARMSLNVAKKPMLDAGIVTLDELGIIGSAFFLTYA
VGKFSNGFLSDYANIGRFMSVSLGLSAITCLFMGMNTATFFFILLWAMNGWFQSVGSAPSCVSIFQWFSPKQRGSVYSIW
GGSRNIGEGITWILTATVVSFFGWRAGFVGAGIATFAAAIAMYFVLKDRPQTYGLPEPAVAYGEDAEIKKKVDPKEIRRA
QLFILKQPTVWIIALACAAMYISRYAMSSWAVLYLQEEKGYSLIDAGFAMSAYPIAGFAGAILAGIISDKVFNANRHIPT
LLYGLANIAGLCLMFWGPQSRVMDAVALGLIGYAIGGLVVFLAGLTACDLMPKTAVGAVKGFIGLCSYIAASAQEIVSAS
LIKIHEVDGVKHYDFSTAQYFWLAAAVVSMFLAMSVWNAKKVVDY
>Mature_445_residues
MLDFFKTRPDQPLIEGTPEKIRSIYKKYQWQVFLGLVLGYAMFYVARMSLNVAKKPMLDAGIVTLDELGIIGSAFFLTYA
VGKFSNGFLSDYANIGRFMSVSLGLSAITCLFMGMNTATFFFILLWAMNGWFQSVGSAPSCVSIFQWFSPKQRGSVYSIW
GGSRNIGEGITWILTATVVSFFGWRAGFVGAGIATFAAAIAMYFVLKDRPQTYGLPEPAVAYGEDAEIKKKVDPKEIRRA
QLFILKQPTVWIIALACAAMYISRYAMSSWAVLYLQEEKGYSLIDAGFAMSAYPIAGFAGAILAGIISDKVFNANRHIPT
LLYGLANIAGLCLMFWGPQSRVMDAVALGLIGYAIGGLVVFLAGLTACDLMPKTAVGAVKGFIGLCSYIAASAQEIVSAS
LIKIHEVDGVKHYDFSTAQYFWLAAAVVSMFLAMSVWNAKKVVDY

Specific function: UhpC is required for uhpT expression, it may act jointly with the uhpB signaling protein [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=419, Percent_Identity=23.6276849642005, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4503847, Length=419, Percent_Identity=23.6276849642005, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI256219483, Length=419, Percent_Identity=23.6276849642005, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI256219543, Length=288, Percent_Identity=25, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI256219564, Length=344, Percent_Identity=22.9651162790698, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI46361976, Length=332, Percent_Identity=24.3975903614458, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87082310, Length=400, Percent_Identity=33, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1788573, Length=420, Percent_Identity=31.6666666666667, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI2367259, Length=402, Percent_Identity=25.8706467661692, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI2367379, Length=301, Percent_Identity=23.5880398671096, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17542316, Length=379, Percent_Identity=23.7467018469657, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI133901854, Length=422, Percent_Identity=24.8815165876777, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133901856, Length=422, Percent_Identity=24.8815165876777, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133930953, Length=368, Percent_Identity=23.9130434782609, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656866, Length=346, Percent_Identity=23.121387283237, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550478, Length=346, Percent_Identity=23.121387283237, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24656861, Length=346, Percent_Identity=23.121387283237, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48615; Mature: 48615

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1569007; 11677609 [H]