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The map label for this gene is tatD [H]

Identifier: 119776341

GI number: 119776341

Start: 3798302

End: 3799105

Strand: Direct

Name: tatD [H]

Synonym: Sama_3209

Alternate gene names: 119776341

Gene position: 3798302-3799105 (Clockwise)

Preceding gene: 119776340

Following gene: 119776342

Centisome position: 88.21

GC content: 58.71

Gene sequence:

>804_bases
ATGCCCCGTTATCTGGACATTGCCGTTAACCTGATTGGCAGTGCCCTCGAATCCGACATTGAGGCCGTAATCGCCGGCGC
CGATGCTGCCGGTGTGTCGCCGTTGATTGTTATTGGCAGCAGCCTCGAAGAGAGCGAGGCGGTTCTGGGCGCCTGCCAGC
GTTTCCCCGGCAAGCTTTATGGCACTGCCGGGGTGCACCCCCATCATGCCTCGAGCTGGCATCAGCACAGCACGGGACTG
CAGCGCCGTCTGTGCGGTGAGAGTGCCATAGTCGCCGTGGGTGAGTGTGGCCTCGACTATAACCGGGACTTTTCTCCCCG
TCCCAAGCAGCGTGAAGCCTTTGCCGCCCAACTGGCACTGGCCTGTGAATTGGGAAAGCCTGTTTTGATGCACGAGCGCG
ATGCCCATGATGACTTCATCGCCATTGTGAGAGAGCATCGCAGCCAACTCAGTGGCGCCCTGTTGCACTGCTTTACCGGC
ACGGCCGCGCAGATGGAAGCCTACATAGACCTTGGACTGCATCTGGGTATTACCGGCTGGGTTTGTGATGAGCGCCGCGG
TCAGGAATTGGCCGCACTGGTGAAAGATATTCCCATCGAACGGCTGCTGATTGAGACCGATAGCCCCTATCTGCTGCCAA
GGTCCATGCGGCCCAAGCCCAAATCAGGTAAAAACCTGCCGCAATATTTACCCTATATCGCCAACGAGATAGCCCGCCTT
CGAGGGGAGGAGCCGGACGACTTTTCCCGGCAGGTATACCACAACAGCCTCACATTCTTTGGCTTGGACAGCGCCCATGG
GTAG

Upstream 100 bases:

>100_bases
AAAAAGGTGCACTGGGCGCATTCTATCTGGGCCTCGAAAGCCGCAATACCACCATCAGGGTAAAACGCCTTAAGTAACTA
TTTCATTATCTTAAGTGAAT

Downstream 100 bases:

>100_bases
ACTCCTGCTGCTGTTACTCGCACTGGGATATAGTCTGCTGGCGCAGGCCGGCGCCCCTGCTTTGGTATACACGCAAGAGT
CGGGGGATGTGATAGAACTG

Product: TatD family hydrolase

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPRYLDIAVNLIGSALESDIEAVIAGADAAGVSPLIVIGSSLEESEAVLGACQRFPGKLYGTAGVHPHHASSWHQHSTGL
QRRLCGESAIVAVGECGLDYNRDFSPRPKQREAFAAQLALACELGKPVLMHERDAHDDFIAIVREHRSQLSGALLHCFTG
TAAQMEAYIDLGLHLGITGWVCDERRGQELAALVKDIPIERLLIETDSPYLLPRSMRPKPKSGKNLPQYLPYIANEIARL
RGEEPDDFSRQVYHNSLTFFGLDSAHG

Sequences:

>Translated_267_residues
MPRYLDIAVNLIGSALESDIEAVIAGADAAGVSPLIVIGSSLEESEAVLGACQRFPGKLYGTAGVHPHHASSWHQHSTGL
QRRLCGESAIVAVGECGLDYNRDFSPRPKQREAFAAQLALACELGKPVLMHERDAHDDFIAIVREHRSQLSGALLHCFTG
TAAQMEAYIDLGLHLGITGWVCDERRGQELAALVKDIPIERLLIETDSPYLLPRSMRPKPKSGKNLPQYLPYIANEIARL
RGEEPDDFSRQVYHNSLTFFGLDSAHG
>Mature_266_residues
PRYLDIAVNLIGSALESDIEAVIAGADAAGVSPLIVIGSSLEESEAVLGACQRFPGKLYGTAGVHPHHASSWHQHSTGLQ
RRLCGESAIVAVGECGLDYNRDFSPRPKQREAFAAQLALACELGKPVLMHERDAHDDFIAIVREHRSQLSGALLHCFTGT
AAQMEAYIDLGLHLGITGWVCDERRGQELAALVKDIPIERLLIETDSPYLLPRSMRPKPKSGKNLPQYLPYIANEIARLR
GEEPDDFSRQVYHNSLTFFGLDSAHG

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=293, Percent_Identity=27.6450511945392, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI225903439, Length=250, Percent_Identity=28.4, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI225903424, Length=188, Percent_Identity=31.3829787234043, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI110349734, Length=229, Percent_Identity=27.0742358078603, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI110349730, Length=229, Percent_Identity=27.0742358078603, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI226061853, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=45.7364341085271, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=30.6513409961686, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082439, Length=265, Percent_Identity=28.3018867924528, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=34.2857142857143, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71980746, Length=270, Percent_Identity=27.7777777777778, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17565396, Length=218, Percent_Identity=27.9816513761468, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=223, Percent_Identity=27.8026905829596, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319416, Length=297, Percent_Identity=25.2525252525253, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=32.7526132404181, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI221330018, Length=301, Percent_Identity=26.9102990033223, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24586117, Length=277, Percent_Identity=27.7978339350181, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29202; Mature: 29071

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYLDIAVNLIGSALESDIEAVIAGADAAGVSPLIVIGSSLEESEAVLGACQRFPGKLY
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEE
GTAGVHPHHASSWHQHSTGLQRRLCGESAIVAVGECGLDYNRDFSPRPKQREAFAAQLAL
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
ACELGKPVLMHERDAHDDFIAIVREHRSQLSGALLHCFTGTAAQMEAYIDLGLHLGITGW
HHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCEEE
VCDERRGQELAALVKDIPIERLLIETDSPYLLPRSMRPKPKSGKNLPQYLPYIANEIARL
EECCCCCHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGEEPDDFSRQVYHNSLTFFGLDSAHG
CCCCCCHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure 
PRYLDIAVNLIGSALESDIEAVIAGADAAGVSPLIVIGSSLEESEAVLGACQRFPGKLY
CCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEE
GTAGVHPHHASSWHQHSTGLQRRLCGESAIVAVGECGLDYNRDFSPRPKQREAFAAQLAL
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
ACELGKPVLMHERDAHDDFIAIVREHRSQLSGALLHCFTGTAAQMEAYIDLGLHLGITGW
HHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCEEE
VCDERRGQELAALVKDIPIERLLIETDSPYLLPRSMRPKPKSGKNLPQYLPYIANEIARL
EECCCCCHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGEEPDDFSRQVYHNSLTFFGLDSAHG
CCCCCCHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]