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The map label for this gene is rimK2

Identifier: 119776292

GI number: 119776292

Start: 3746106

End: 3747011

Strand: Reverse

Name: rimK2

Synonym: Sama_3160

Alternate gene names: 119776292

Gene position: 3747011-3746106 (Counterclockwise)

Preceding gene: 119776293

Following gene: 119776287

Centisome position: 87.02

GC content: 53.64

Gene sequence:

>906_bases
ATGAAAATCGGTGTGTTGTCCCAATTCCCCGAGCTCTACTCGACACGTCGATTGGTGGAGGCTTGTGAATCCAGGGGGCA
TGAGGCCTGGGTAATAAACCCTATCAACTGCTACATGAATATCAACTCGGTCAAACCCAGCATCCATCTCGAAGGGGAAG
AGGTGCCCATGTTTGATGCCATCATTCCCAGAATTCACGCCAGCGTTACCTTCTACGGTTGTGCCGTGGTGCGTCAGTTT
GAAATGATGGGAGTATTTGCTGCCAATGATTCCATTTCCATTGCACGCTCACGGGATAAATTGCGGGCATTGCAGTTGTT
GTCCCGTAAAGGTATTGGCATGCCGGTGACAGGATTTGCCAACAAACCCAATAATATTCCTGACCTTATCAATATGGTAG
GCGGTGCTCCTCTGGTGATTAAACTGCTTGAGGGCACTCAGGGTATCGGTGTGGTGCTGGCTGAAACCCGCAAGGCGGCC
GAAAGTGTGATTGAGGCGTTTTTAGGGCTTAAGGCCAACATCATGGTGCAGGAATATATCAAAGAGGCCAATGGCAGCGA
CATCCGCTGTTTTGTGGTGGGTGATAAGGTAGTGGCCGCTATGCGCAGACAGGGCCCGGAAGGCGACTTCCGCTCTAATC
TGCATCTGGGTGGTTCGGCTGAGCCGGTGAAAATCACGCCGCAGGAGCGCAAATCCGCAGTCGCGGCCGCCAAGGCCATG
GGATTGGTGGTTGCCGGGGTGGATATTTTGCGTTCAGCCCGTGGTCCATTGGTGCTGGAGGTGAACTCGGCACCGGGCAT
CGAGGGGATTGAACAGGCAACCGGTATCAAGGTTGCTGAACCCATCGTTGAGTATATTGAAAAAGTGGTGGCGGCCCGCC
GGGCCAACCACCAGGTGATTGCCTGA

Upstream 100 bases:

>100_bases
TACCAAATTCCAACAGAGATAACTTGCCAAGCCTTGGTGATTACTACAAAATTTTCTCACTTAACTTTCTTTGGCGCCTG
AGTCGCCACGGTATACTGCG

Downstream 100 bases:

>100_bases
CTTCAGTCAGATCTCAATACTCAGAGTGCGAAGCCGTATGACCAGCGCAGCACCACTTTGGGGTCATCCTCGGCAAGGTC
GGTGTCAGATACAGTAAAGC

Product: ribosomal protein S6 modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKIGVLSQFPELYSTRRLVEACESRGHEAWVINPINCYMNINSVKPSIHLEGEEVPMFDAIIPRIHASVTFYGCAVVRQF
EMMGVFAANDSISIARSRDKLRALQLLSRKGIGMPVTGFANKPNNIPDLINMVGGAPLVIKLLEGTQGIGVVLAETRKAA
ESVIEAFLGLKANIMVQEYIKEANGSDIRCFVVGDKVVAAMRRQGPEGDFRSNLHLGGSAEPVKITPQERKSAVAAAKAM
GLVVAGVDILRSARGPLVLEVNSAPGIEGIEQATGIKVAEPIVEYIEKVVAARRANHQVIA

Sequences:

>Translated_301_residues
MKIGVLSQFPELYSTRRLVEACESRGHEAWVINPINCYMNINSVKPSIHLEGEEVPMFDAIIPRIHASVTFYGCAVVRQF
EMMGVFAANDSISIARSRDKLRALQLLSRKGIGMPVTGFANKPNNIPDLINMVGGAPLVIKLLEGTQGIGVVLAETRKAA
ESVIEAFLGLKANIMVQEYIKEANGSDIRCFVVGDKVVAAMRRQGPEGDFRSNLHLGGSAEPVKITPQERKSAVAAAKAM
GLVVAGVDILRSARGPLVLEVNSAPGIEGIEQATGIKVAEPIVEYIEKVVAARRANHQVIA
>Mature_301_residues
MKIGVLSQFPELYSTRRLVEACESRGHEAWVINPINCYMNINSVKPSIHLEGEEVPMFDAIIPRIHASVTFYGCAVVRQF
EMMGVFAANDSISIARSRDKLRALQLLSRKGIGMPVTGFANKPNNIPDLINMVGGAPLVIKLLEGTQGIGVVLAETRKAA
ESVIEAFLGLKANIMVQEYIKEANGSDIRCFVVGDKVVAAMRRQGPEGDFRSNLHLGGSAEPVKITPQERKSAVAAAKAM
GLVVAGVDILRSARGPLVLEVNSAPGIEGIEQATGIKVAEPIVEYIEKVVAARRANHQVIA

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI164663810, Length=224, Percent_Identity=27.6785714285714, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI134254462, Length=223, Percent_Identity=28.2511210762332, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787076, Length=288, Percent_Identity=62.1527777777778, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIMK2_SHEAM (A1SAF6)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_929032.1
- STRING:   A1SAF6
- GeneID:   4605407
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3160
- NMPDR:   fig|326297.7.peg.2973
- eggNOG:   COG0189
- HOGENOM:   HBG679591
- OMA:   DERSIHY
- PhylomeDB:   A1SAF6
- ProtClustDB:   CLSK905802
- GO:   GO:0006412
- HAMAP:   MF_01552
- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR004666
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- TIGRFAMs:   TIGR00768

Pfam domain/function: PF08443 RimK

EC number: NA

Molecular weight: Translated: 32435; Mature: 32435

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVLSQFPELYSTRRLVEACESRGHEAWVINPINCYMNINSVKPSIHLEGEEVPMFDA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCEEEECCCCCCHHHH
IIPRIHASVTFYGCAVVRQFEMMGVFAANDSISIARSRDKLRALQLLSRKGIGMPVTGFA
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCC
NKPNNIPDLINMVGGAPLVIKLLEGTQGIGVVLAETRKAAESVIEAFLGLKANIMVQEYI
CCCCCCHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
KEANGSDIRCFVVGDKVVAAMRRQGPEGDFRSNLHLGGSAEPVKITPQERKSAVAAAKAM
HHCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCEECCCCCCCEEECHHHHHHHHHHHHHH
GLVVAGVDILRSARGPLVLEVNSAPGIEGIEQATGIKVAEPIVEYIEKVVAARRANHQVI
HHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
A
C
>Mature Secondary Structure
MKIGVLSQFPELYSTRRLVEACESRGHEAWVINPINCYMNINSVKPSIHLEGEEVPMFDA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCEEEECCCCCCHHHH
IIPRIHASVTFYGCAVVRQFEMMGVFAANDSISIARSRDKLRALQLLSRKGIGMPVTGFA
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCC
NKPNNIPDLINMVGGAPLVIKLLEGTQGIGVVLAETRKAAESVIEAFLGLKANIMVQEYI
CCCCCCHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHH
KEANGSDIRCFVVGDKVVAAMRRQGPEGDFRSNLHLGGSAEPVKITPQERKSAVAAAKAM
HHCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCEECCCCCCCEEECHHHHHHHHHHHHHH
GLVVAGVDILRSARGPLVLEVNSAPGIEGIEQATGIKVAEPIVEYIEKVVAARRANHQVI
HHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA