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The map label for this gene is caiD [C]

Identifier: 119776267

GI number: 119776267

Start: 3723299

End: 3724105

Strand: Reverse

Name: caiD [C]

Synonym: Sama_3135

Alternate gene names: 119776267

Gene position: 3724105-3723299 (Counterclockwise)

Preceding gene: 119776270

Following gene: 119776266

Centisome position: 86.48

GC content: 55.89

Gene sequence:

>807_bases
ATGACTCAACCCCCAGTCACTCTGGTCATAAAGGATGGCATAGCCTTTGTGACATTAAATCGACCAGAAAAATTCAATGC
GTTGAATTATGAGATGTTTTCAGCGATCTGCAGGGTGCAGAAGCTGCTGGCACGAAACAGACAGGTGCGGGTGGTGATAC
TGCAAGGCGCCCAGGGGCACTTCTCCTCTGGGCTTGATATCAAGAGTGTCACCCGTAAGCCGCTGCAGCCACTGGGGCTG
CTGGCCAAGTGGCTGCCCGGTAATGCCAATCTGGCTCAGCGGGTCTCCATCGGCTGGAGCCGTTTGCCAGTCCCCGTTAT
TGCTGTCATCGAAGGCTATTGTTATGGCGGTGGCATGCAGATTGCGCTGGGGGCCGATTTTCGCTTTGCGGCTGAAAACG
CCGAGCTGTCCATTATGGAAGCCAAGTGGGGGCTTGTGCCCGACATGGCTGGACTGGTGAGCCTCAGAGGGATACTGCCA
AAAGACAAGGCGCTGGAATTGTCGATGACTGCCAGGGTAATCGAGGCCGATGAGGCAGCTTCCCTTGGCTTGGTAACAAG
GGTCACGGCTGCGCCTATGGATGACGCCCTCGCCTTTGCCGGGGAGTTAATGACACGTTCGCCTGATGCTCTGGCTGCCA
TCAAGGGCTCGATTCATCGTAGTTGGAGTGGCAGTATTCGCCGTTTGCTGGCGCGGGAGTCATGGTATCAGGTGCGTCTG
CTGCTGGGGAAAAACTTTGCCATCGCCGCCCGGCGTCAGCAGGGTAAAACCGACAGAGACTACAAACCACGGCAAAAATT
CTGGTAA

Upstream 100 bases:

>100_bases
AATACTGACGGATGTCAAAAAGTCTGGCTATGTTACGTTGAATAGCCATTTATGCCAAATATGTTAACATCTCTTCTGGA
CAGACCAGTTAGGATGCGGC

Downstream 100 bases:

>100_bases
TCCACTCACAATCCCCGGGATTGCACTTGCGTGTACCCAACCAAAGCGCCCACAATCGGCGCTTTATTTTTAGGTGTATT
TTCAAGGAGCTGAAAAATGA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTQPPVTLVIKDGIAFVTLNRPEKFNALNYEMFSAICRVQKLLARNRQVRVVILQGAQGHFSSGLDIKSVTRKPLQPLGL
LAKWLPGNANLAQRVSIGWSRLPVPVIAVIEGYCYGGGMQIALGADFRFAAENAELSIMEAKWGLVPDMAGLVSLRGILP
KDKALELSMTARVIEADEAASLGLVTRVTAAPMDDALAFAGELMTRSPDALAAIKGSIHRSWSGSIRRLLARESWYQVRL
LLGKNFAIAARRQQGKTDRDYKPRQKFW

Sequences:

>Translated_268_residues
MTQPPVTLVIKDGIAFVTLNRPEKFNALNYEMFSAICRVQKLLARNRQVRVVILQGAQGHFSSGLDIKSVTRKPLQPLGL
LAKWLPGNANLAQRVSIGWSRLPVPVIAVIEGYCYGGGMQIALGADFRFAAENAELSIMEAKWGLVPDMAGLVSLRGILP
KDKALELSMTARVIEADEAASLGLVTRVTAAPMDDALAFAGELMTRSPDALAAIKGSIHRSWSGSIRRLLARESWYQVRL
LLGKNFAIAARRQQGKTDRDYKPRQKFW
>Mature_267_residues
TQPPVTLVIKDGIAFVTLNRPEKFNALNYEMFSAICRVQKLLARNRQVRVVILQGAQGHFSSGLDIKSVTRKPLQPLGLL
AKWLPGNANLAQRVSIGWSRLPVPVIAVIEGYCYGGGMQIALGADFRFAAENAELSIMEAKWGLVPDMAGLVSLRGILPK
DKALELSMTARVIEADEAASLGLVTRVTAAPMDDALAFAGELMTRSPDALAAIKGSIHRSWSGSIRRLLARESWYQVRLL
LGKNFAIAARRQQGKTDRDYKPRQKFW

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=241, Percent_Identity=29.8755186721992, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI194097323, Length=212, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI68989263, Length=194, Percent_Identity=28.3505154639175, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI45643119, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI260275230, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI260274832, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI157694516, Length=237, Percent_Identity=24.0506329113924, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI20127408, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI213417737, Length=242, Percent_Identity=24.7933884297521, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI221142681, Length=211, Percent_Identity=37.4407582938389, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790281, Length=182, Percent_Identity=29.6703296703297, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787659, Length=225, Percent_Identity=28, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787660, Length=231, Percent_Identity=29.004329004329, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788682, Length=182, Percent_Identity=31.8681318681319, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082183, Length=240, Percent_Identity=24.5833333333333, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=232, Percent_Identity=31.4655172413793, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=228, Percent_Identity=30.2631578947368, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=25.5060728744939, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=26.7281105990783, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=23.7903225806452, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25141363, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=202, Percent_Identity=24.2574257425743, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=182, Percent_Identity=29.1208791208791, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=27.734375, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653139, Length=207, Percent_Identity=32.3671497584541, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=24.0816326530612, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=24.0816326530612, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357171, Length=205, Percent_Identity=30.2439024390244, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24650670, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29499; Mature: 29368

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPPVTLVIKDGIAFVTLNRPEKFNALNYEMFSAICRVQKLLARNRQVRVVILQGAQGH
CCCCCEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
FSSGLDIKSVTRKPLQPLGLLAKWLPGNANLAQRVSIGWSRLPVPVIAVIEGYCYGGGMQ
CCCCCCHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHEEHHHCEEECCCEE
IALGADFRFAAENAELSIMEAKWGLVPDMAGLVSLRGILPKDKALELSMTARVIEADEAA
EEECCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEEHHEEEEECCCCC
SLGLVTRVTAAPMDDALAFAGELMTRSPDALAAIKGSIHRSWSGSIRRLLARESWYQVRL
CCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHEEEE
LLGKNFAIAARRQQGKTDRDYKPRQKFW
EECCCEEEEEHHHCCCCCCCCCCHHCCC
>Mature Secondary Structure 
TQPPVTLVIKDGIAFVTLNRPEKFNALNYEMFSAICRVQKLLARNRQVRVVILQGAQGH
CCCCEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
FSSGLDIKSVTRKPLQPLGLLAKWLPGNANLAQRVSIGWSRLPVPVIAVIEGYCYGGGMQ
CCCCCCHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHEEHHHCEEECCCEE
IALGADFRFAAENAELSIMEAKWGLVPDMAGLVSLRGILPKDKALELSMTARVIEADEAA
EEECCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEEHHEEEEECCCCC
SLGLVTRVTAAPMDDALAFAGELMTRSPDALAAIKGSIHRSWSGSIRRLLARESWYQVRL
CCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHEEEE
LLGKNFAIAARRQQGKTDRDYKPRQKFW
EECCCEEEEEHHHCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA