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The map label for this gene is groEL [H]

Identifier: 119776256

GI number: 119776256

Start: 3704504

End: 3706141

Strand: Reverse

Name: groEL [H]

Synonym: Sama_3124

Alternate gene names: 119776256

Gene position: 3706141-3704504 (Counterclockwise)

Preceding gene: 119776257

Following gene: 119776254

Centisome position: 86.07

GC content: 55.68

Gene sequence:

>1638_bases
ATGGCAGCTAAAGAAGTAGTATTTGGTAACGACGCCCGCGTAAAAATGCTGGCCGGTGTAAACATTCTGGCCAACGCCGT
TAAAGTCACCCTGGGCCCCAAAGGCCGTAACGTGGTTCTGGAAAAGAGCTTCGGCGCGCCGCTCATCACCAAAGACGGTG
TCTCTGTAGCCAAAGAAATCGAACTGGAAGACAAGTTCGAGAACATGGGCGCCCAGATGGTGAAGGAAGTGGCTTCCAAG
GCCAACGACGCTGCCGGTGATGGCACCACCACCGCCACCGTACTGGCTCAGGCCATTGTTAACGAAGGTCTGAAAGCCGT
TGCCGCTGGCATGAACCCAATGGATCTGAAGCGCGGTATCGACAAAGCCGTTGCCGCCGCTGTGGTTGAACTCAAAGCCC
TGTCTCAGGAATGTGCCGACTCCAAGGCCATTGCTCAGGTAGGTACCATCTCTGCCAACTCAGACGAGTCCATCGGTGAC
ATCATTGCCACCGCCATGGAAAAAGTAGGCAAAGAAGGCGTTATCACCGTTGAAGAAGGCCAGGCGCTGGAAAACGAACT
GGACGTAGTAGAAGGTATGCAGTTCGACCGCGGCTACCTGTCTCCTTACTTCATCAACAAGCCAGAAACCGGCGCTGTTG
AACTGGACAACCCATTCGTACTGCTGGTTGACAAGAAGATCTCCAACATCCGCGAACTGCTGCCTATCCTCGAAGGTCTG
GCCAAGACCGGCAAGCCACTGCTGATCGTTGCCGAAGACGTGGAAGGCGAAGCCCTGGCGACTCTGGTAGTGAACAACAT
GCGCGGTATCGTGAAGGTTGCTGCCGTTAAAGCCCCAGGCTTTGGTGACCGTCGCAAGGCCATGCTGCAGGATATCGCCA
TCCTCACCGGTGGTACTGTTATCGCTGAAGAAATCGGTCTGGAGCTGGAAAAAGCCACTCTGGAAGATCTGGGTACTGCC
AAGCGCGTAGTGATCACCAAAGACAACACCACCATCATCGATGGCAACGGTGCTGAAGAGCAGATCAAGGCTCGCGTAGG
TCAGATCAAACAGCAAATCGAAGAAACCACTTCCGATTACGACCGTGAAAAACTGCAGGAGCGTATGGCCAAGCTGGCCG
GCGGTGTTGCCGTTATCAAGGTTGGCGCTGCCACCGAAGTGGAAATGAAAGAGAAGAAAGCCCGCGTTGAAGACGCCCTG
CACGCCACCCGCGCCGCCGTTGAAGAAGGCGTGGTTCCAGGCGGCGGTGTAGCCCTGGTACGTGTTGCTTCCAAGATTGC
CAACGTAGACGTTGCCAACGAAGATCAGAAGCACGGTGTAGTTATCGCTCTGCGCGCCATGGAAGCCCCACTGCGCCAAA
TCGCCACCAACGCCGGTGAAGAAGCCTCTGTAGTGGCCAACACTGTGAAGAACGGCTCTGGTAACTTCGGTTACAACGCC
GGTAACGACAGCTACGGCGACATGCTGGAAATGGGTATCCTGGATCCAACCAAGGTAACCCGCTCTGCACTGCAGTTCGC
CGCCTCTGTAGCAGGTCTGATGATCACCACCGAAGCCATGGTAGCCGAGCTGCCGAAGGCTGATGCCCCTGATATGGGTG
GTATGGGTGGTGGTATGGGCGGCATGGGCATGATGTAA

Upstream 100 bases:

>100_bases
GTACTGATCCTGTCGGAAATGGATCTGATGGCTGTAGTGGACTAATCCACTCAAATTGTGAAATTTCAGTCTAACTCAAA
GTATTTAAAGGAAATCGAAC

Downstream 100 bases:

>100_bases
CTCTAGCTGGTTAAAATCGTTTATAGCGGCGTTATCCTGCCGCTCGTTTAGACAGCTAAACGTCGCGGCAGGATGCCTTG
CTCTAAAACGATTTTTCCTG

Product: chaperonin GroEL

Products: NA

Alternate protein names: GroEL protein; Protein Cpn60 [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLEKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASK
ANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVAAAVVELKALSQECADSKAIAQVGTISANSDESIGD
IIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGAVELDNPFVLLVDKKISNIRELLPILEGL
AKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTA
KRVVITKDNTTIIDGNGAEEQIKARVGQIKQQIEETTSDYDREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDAL
HATRAAVEEGVVPGGGVALVRVASKIANVDVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNA
GNDSYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVAELPKADAPDMGGMGGGMGGMGMM

Sequences:

>Translated_545_residues
MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLEKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASK
ANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVAAAVVELKALSQECADSKAIAQVGTISANSDESIGD
IIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGAVELDNPFVLLVDKKISNIRELLPILEGL
AKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTA
KRVVITKDNTTIIDGNGAEEQIKARVGQIKQQIEETTSDYDREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDAL
HATRAAVEEGVVPGGGVALVRVASKIANVDVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNA
GNDSYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVAELPKADAPDMGGMGGGMGGMGMM
>Mature_544_residues
AAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLEKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKA
NDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVAAAVVELKALSQECADSKAIAQVGTISANSDESIGDI
IATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGAVELDNPFVLLVDKKISNIRELLPILEGLA
KTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTAK
RVVITKDNTTIIDGNGAEEQIKARVGQIKQQIEETTSDYDREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALH
ATRAAVEEGVVPGGGVALVRVASKIANVDVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNAG
NDSYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVAELPKADAPDMGGMGGGMGGMGMM

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions [H]

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family [H]

Homologues:

Organism=Homo sapiens, GI41399285, Length=525, Percent_Identity=51.8095238095238, Blast_Score=529, Evalue=1e-150,
Organism=Homo sapiens, GI31542947, Length=525, Percent_Identity=51.8095238095238, Blast_Score=529, Evalue=1e-150,
Organism=Escherichia coli, GI1790586, Length=532, Percent_Identity=83.6466165413534, Blast_Score=882, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17555558, Length=529, Percent_Identity=51.6068052930057, Blast_Score=538, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI193210679, Length=211, Percent_Identity=51.6587677725119, Blast_Score=214, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6323288, Length=526, Percent_Identity=55.5133079847909, Blast_Score=560, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6322524, Length=162, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641193, Length=527, Percent_Identity=53.3206831119545, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI24641191, Length=527, Percent_Identity=53.3206831119545, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI45550936, Length=524, Percent_Identity=49.8091603053435, Blast_Score=518, Evalue=1e-147,
Organism=Drosophila melanogaster, GI45550132, Length=524, Percent_Identity=49.8091603053435, Blast_Score=518, Evalue=1e-147,
Organism=Drosophila melanogaster, GI45550935, Length=524, Percent_Identity=49.8091603053435, Blast_Score=518, Evalue=1e-147,
Organism=Drosophila melanogaster, GI17864606, Length=542, Percent_Identity=42.9889298892989, Blast_Score=446, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24584129, Length=528, Percent_Identity=37.1212121212121, Blast_Score=330, Evalue=2e-90,
Organism=Drosophila melanogaster, GI19921262, Length=528, Percent_Identity=37.1212121212121, Blast_Score=330, Evalue=2e-90,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423 [H]

Pfam domain/function: PF00118 Cpn60_TCP1 [H]

EC number: NA

Molecular weight: Translated: 56936; Mature: 56805

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLEKSFGAPLITKDGVSVAKEI
CCCCCEEECCCCCEEEECCHHHHHHHEEEEECCCCCEEEEECCCCCCEEECCCCHHHHHH
ELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DKAVAAAVVELKALSQECADSKAIAQVGTISANSDESIGDIIATAMEKVGKEGVITVEEG
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCC
QALENELDVVEGMQFDRGYLSPYFINKPETGAVELDNPFVLLVDKKISNIRELLPILEGL
CHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHH
AKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTV
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCH
IAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGAEEQIKARVGQIKQQIEETTSDY
HHHHHCCHHHHHHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
DREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALV
HHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RVASKIANVDVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNA
HHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC
GNDSYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVAELPKADAPDMGGMGGGMG
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GMGMM
CCCCC
>Mature Secondary Structure 
AAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLEKSFGAPLITKDGVSVAKEI
CCCCEEECCCCCEEEECCHHHHHHHEEEEECCCCCEEEEECCCCCCEEECCCCHHHHHH
ELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DKAVAAAVVELKALSQECADSKAIAQVGTISANSDESIGDIIATAMEKVGKEGVITVEEG
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCC
QALENELDVVEGMQFDRGYLSPYFINKPETGAVELDNPFVLLVDKKISNIRELLPILEGL
CHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHH
AKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTV
HHCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCH
IAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGAEEQIKARVGQIKQQIEETTSDY
HHHHHCCHHHHHHHHHCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
DREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALV
HHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
RVASKIANVDVANEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNA
HHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC
GNDSYGDMLEMGILDPTKVTRSALQFAASVAGLMITTEAMVAELPKADAPDMGGMGGGMG
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GMGMM
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA