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The map label for this gene is pabA [H]

Identifier: 119776147

GI number: 119776147

Start: 3590359

End: 3591009

Strand: Reverse

Name: pabA [H]

Synonym: Sama_3015

Alternate gene names: 119776147

Gene position: 3591009-3590359 (Counterclockwise)

Preceding gene: 119776149

Following gene: 119776146

Centisome position: 83.39

GC content: 53.76

Gene sequence:

>651_bases
ATGATCCGCAGGCCGCTCTGTGCTAGGATTCGCGGCCTGTTCTGTTTGGATTTCAACGCGCGGACGAATAAAAGCATGTT
GCTCATGATAGACAACTACGACTCTTTTACCTTTAACCTGGTGCAGTATTTTCAGCAGCTGGGGGAAGAGGTGGTTGTCC
GTCGCCATGACGATATTACGCTGGAGGAAATCGCTGCGCTGGCACCGGACTATTTGGTGATTTCACCCGGCCCCTGTACC
CCGGATGACGCGGGTGTTTCCCTGGACGCCATCACTCATTTTGCCGGTAAGTTGCCCATTCTGGGGGTGTGCCTGGGGCA
TCAGGCGATGGCCCAGGTATTTGGCGCTAAAGTGATCCGTGCCGGAAGGGTGATGCATGGCAAAACCAGTGACATCAGCC
ATAACAATCAGCGCCTGTTTCGTGGCCTCAATAACCCGCTGAGGGTCACCCGTTATCACTCGCTGTTGGTGGAGTCCGTA
CCCGAAGGCTTTGTGATGGATGCCTGGTTTGACGATCCTGTCCATGGACGTGAAATCATGGCCATCAGCCATAAGTCCTT
ACCGCTGTATGGGGTGCAGTTCCATCCCGAATCCATCCTTACCGAGCAAGGGCTCGAATTGCTTGGTAATTTCCTTAAAA
TCCCCGTCTGA

Upstream 100 bases:

>100_bases
TTGGCGTAACTGAGCAGCCGTTTCCCCCAAAATGCCATAGAGTTTACTGACGAAGGTTTGATAATCATCCCTTAAGCATA
GACATAGTTCCGGCCATTGG

Downstream 100 bases:

>100_bases
CACCGTGTCTTGATTTTCTGTTACAAGTTTTCTCGTTTACCTTTTGTGACCACGCCAGTGTGACAGGCGCAAATATGGTA
TAACTGCGCCATTCCAAAAA

Product: para-aminobenzoate synthase glutamine amidotransferase, component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MIRRPLCARIRGLFCLDFNARTNKSMLLMIDNYDSFTFNLVQYFQQLGEEVVVRRHDDITLEEIAALAPDYLVISPGPCT
PDDAGVSLDAITHFAGKLPILGVCLGHQAMAQVFGAKVIRAGRVMHGKTSDISHNNQRLFRGLNNPLRVTRYHSLLVESV
PEGFVMDAWFDDPVHGREIMAISHKSLPLYGVQFHPESILTEQGLELLGNFLKIPV

Sequences:

>Translated_216_residues
MIRRPLCARIRGLFCLDFNARTNKSMLLMIDNYDSFTFNLVQYFQQLGEEVVVRRHDDITLEEIAALAPDYLVISPGPCT
PDDAGVSLDAITHFAGKLPILGVCLGHQAMAQVFGAKVIRAGRVMHGKTSDISHNNQRLFRGLNNPLRVTRYHSLLVESV
PEGFVMDAWFDDPVHGREIMAISHKSLPLYGVQFHPESILTEQGLELLGNFLKIPV
>Mature_216_residues
MIRRPLCARIRGLFCLDFNARTNKSMLLMIDNYDSFTFNLVQYFQQLGEEVVVRRHDDITLEEIAALAPDYLVISPGPCT
PDDAGVSLDAITHFAGKLPILGVCLGHQAMAQVFGAKVIRAGRVMHGKTSDISHNNQRLFRGLNNPLRVTRYHSLLVESV
PEGFVMDAWFDDPVHGREIMAISHKSLPLYGVQFHPESILTEQGLELLGNFLKIPV

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=143, Percent_Identity=37.0629370629371, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=65.0793650793651, Blast_Score=253, Evalue=8e-69,
Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=43.3862433862434, Blast_Score=162, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322638, Length=204, Percent_Identity=46.078431372549, Blast_Score=178, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6324361, Length=221, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6323873, Length=149, Percent_Identity=32.2147651006711, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281365319, Length=145, Percent_Identity=32.4137931034483, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 24198; Mature: 24198

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRPLCARIRGLFCLDFNARTNKSMLLMIDNYDSFTFNLVQYFQQLGEEVVVRRHDDIT
CCCCCHHHHHCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC
LEEIAALAPDYLVISPGPCTPDDAGVSLDAITHFAGKLPILGVCLGHQAMAQVFGAKVIR
HHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEHHHCHHHHHHHHHHHHHH
AGRVMHGKTSDISHNNQRLFRGLNNPLRVTRYHSLLVESVPEGFVMDAWFDDPVHGREIM
HCCEECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
AISHKSLPLYGVQFHPESILTEQGLELLGNFLKIPV
EEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRRPLCARIRGLFCLDFNARTNKSMLLMIDNYDSFTFNLVQYFQQLGEEVVVRRHDDIT
CCCCCHHHHHCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC
LEEIAALAPDYLVISPGPCTPDDAGVSLDAITHFAGKLPILGVCLGHQAMAQVFGAKVIR
HHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEHHHCHHHHHHHHHHHHHH
AGRVMHGKTSDISHNNQRLFRGLNNPLRVTRYHSLLVESVPEGFVMDAWFDDPVHGREIM
HCCEECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
AISHKSLPLYGVQFHPESILTEQGLELLGNFLKIPV
EEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]