Click here to switch to the map view.

The map label for this gene is yheS [H]

Identifier: 119776128

GI number: 119776128

Start: 3568613

End: 3570520

Strand: Direct

Name: yheS [H]

Synonym: Sama_2996

Alternate gene names: 119776128

Gene position: 3568613-3570520 (Clockwise)

Preceding gene: 119776125

Following gene: 119776129

Centisome position: 82.87

GC content: 57.13

Gene sequence:

>1908_bases
ATGATCACCCTGTCCCAGGCCCAGCTTATCCGTGGCAGCAAAGTACTGCTGGATGAGGCCAATCTCACTATTTACCCCGG
TCACAAGGTCGGCCTTGTTGGCGCCAATGGCACCGGCAAATCCTCATTGCTGGCATTGATCATGGGCAAACTCAGCCTGG
ACAAGGGCGATATTCAGGTACCCCGCGAGTGGCGCATTGCCTCTGTGGCTCAGGAAACCCCGGCACTGGAAGTCTCGGCA
CTGGAATATGTGCTCGATGGCGACATGGAGTTTCGTGAACTCGAAGCGGCTTTAAGAAAAGCAGAGACCGATAACGATGG
CCATGCCATTGCAGACCTGCACGGTAAGCTTGATGCCATCGGCGGCTACAGCATACGTGCCCGCGCCGGCGCCCTGCTGG
CGGGTTTGGGCTTCAGCGAAGAAAAGCAGTCGGTCAGCGTGAAGAGCTTTTCCGGTGGCTGGCGTATGCGCCTTAACCTG
GCTCAGGCGCTGCTTTGCCGATCAGAATTGTTGTTGCTTGACGAACCGACCAACCACCTTGATCTGGACACCATGTTCTG
GCTCGAGGATTGGATCAAGAGCTACCCGGGCACCCTAGTGCTCATCAGCCACGATCGCGACTTTATCGACGCCATTGTGG
ATGAAATCGTCCATGTGGAAAACCAGAAGCTTAACTTCTACAAGGGCAACTACAGCACGTTTGAGCGCACCCGCGCCGAG
CGTATGGCGCAGCAGCAGGTGGCCTTTGAGCGCCAACAGCGGGAACGCGCCCACATGCAATCCTTCGTCGACCGTTTCCG
CTACAAGGCCAGCAAGGCCAAGCAGGCACAAAGCCGTTTGAAGGCATTGGAAAAGATGACTGAGCTCTTGCCCGCCAAGG
CCGACAGCCAGTTCTATATGGAGTTTCGCGAACCCGCCAGTCTGCCAAACCCCTTGGTGGCCATGGAAAACGTGTCTGTG
GGTTATGGTGAAACGCCCATCCTCGGTAAGGTGCATTTAAATCTGGTGCCCGGTGCCCGCATTGGTCTTTTGGGCCGCAA
CGGCGCCGGTAAATCGACCCTGATTAAATTGCTGGCGAGCGAGCTCAAACCGCTCACCGGCAAGTACGAGCCCAACCCAG
GCCTCACCATTGGCTACTTTGCCCAGCATCAGCTGGAGTATTTGCACATGGATGACAGCCCGCTGATGCACCTGCAGCGA
CTGGCGCCCAGCCACCGAGAACAGGAACTGCGGGACTTCCTCGGTGGTTTTGGCTTTAATGGCGACATGGCACTCTCGCC
GGTCGCGCCCTTCTCCGGCGGCGAAAAGGCCCGTCTGGTACTGGCGCTGCTGGTGTGGCAAAGCCCCAACCTGCTGCTGC
TGGACGAACCCACCAACCACCTGGATCTGGAAATGCGCCACGCTCTGACGCTGGCACTGCAAACCTTTGAAGGTGCCATG
GTGATAGTGTCCCACGACAGGCACCTGCTCAGGCTCACCTGTAATGACTACTATCTGGTAGATGCCGGTCAGGTCAGCAG
TTTCGAAGGCGACCTTGAGGACTACCATCAGTGGCTGCTGGATGCCGCAAAGGCAGCGGCCGCCAAGGCCAGCGATAACG
ATGCAGAGCGCCCGGCGCAGGACAAGAAGCAGCAAAAGCGACTGGAAGCTGAACTGCGCCAAAAGCTCTCGCCCCTGAGA
AAGCAGCAAACCAAACTCGAAGATGAGCAGCATAAAATCGCCAGCCGTCTCGCACTGATTGAAGAACGTCTGGCCGATAC
CAGTTTGTATGAGGCGCAAAACAAGGCGGAGCTGACTAAAATACTGGCCGAGCGAACCACTCTTGGTCAGCAGCAGGAAG
AAAGCGAAATGGCGTGGTTAGAGCTTCAGGAGCAAATTGACGTTATCGAACAGGCCGCCCAGCTCTGA

Upstream 100 bases:

>100_bases
GCCACAGCTTACGCAGGCAACCCTAATCCCGGCTTCGCGCTGGATGCCGGGCCTGAACTTGGTTATTATTCTGCCCTTTA
TATCTGTATGTGGACCCCAG

Downstream 100 bases:

>100_bases
CGCAGCACGAATGTCGGCACCCATAAGTCCGTCACAATGGAATAAGGAGTCTCCCATTGATATCTGAGGAAGTATTCACC
CGCGAACTCTGGCAAGCCTG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MITLSQAQLIRGSKVLLDEANLTIYPGHKVGLVGANGTGKSSLLALIMGKLSLDKGDIQVPREWRIASVAQETPALEVSA
LEYVLDGDMEFRELEAALRKAETDNDGHAIADLHGKLDAIGGYSIRARAGALLAGLGFSEEKQSVSVKSFSGGWRMRLNL
AQALLCRSELLLLDEPTNHLDLDTMFWLEDWIKSYPGTLVLISHDRDFIDAIVDEIVHVENQKLNFYKGNYSTFERTRAE
RMAQQQVAFERQQRERAHMQSFVDRFRYKASKAKQAQSRLKALEKMTELLPAKADSQFYMEFREPASLPNPLVAMENVSV
GYGETPILGKVHLNLVPGARIGLLGRNGAGKSTLIKLLASELKPLTGKYEPNPGLTIGYFAQHQLEYLHMDDSPLMHLQR
LAPSHREQELRDFLGGFGFNGDMALSPVAPFSGGEKARLVLALLVWQSPNLLLLDEPTNHLDLEMRHALTLALQTFEGAM
VIVSHDRHLLRLTCNDYYLVDAGQVSSFEGDLEDYHQWLLDAAKAAAAKASDNDAERPAQDKKQQKRLEAELRQKLSPLR
KQQTKLEDEQHKIASRLALIEERLADTSLYEAQNKAELTKILAERTTLGQQQEESEMAWLELQEQIDVIEQAAQL

Sequences:

>Translated_635_residues
MITLSQAQLIRGSKVLLDEANLTIYPGHKVGLVGANGTGKSSLLALIMGKLSLDKGDIQVPREWRIASVAQETPALEVSA
LEYVLDGDMEFRELEAALRKAETDNDGHAIADLHGKLDAIGGYSIRARAGALLAGLGFSEEKQSVSVKSFSGGWRMRLNL
AQALLCRSELLLLDEPTNHLDLDTMFWLEDWIKSYPGTLVLISHDRDFIDAIVDEIVHVENQKLNFYKGNYSTFERTRAE
RMAQQQVAFERQQRERAHMQSFVDRFRYKASKAKQAQSRLKALEKMTELLPAKADSQFYMEFREPASLPNPLVAMENVSV
GYGETPILGKVHLNLVPGARIGLLGRNGAGKSTLIKLLASELKPLTGKYEPNPGLTIGYFAQHQLEYLHMDDSPLMHLQR
LAPSHREQELRDFLGGFGFNGDMALSPVAPFSGGEKARLVLALLVWQSPNLLLLDEPTNHLDLEMRHALTLALQTFEGAM
VIVSHDRHLLRLTCNDYYLVDAGQVSSFEGDLEDYHQWLLDAAKAAAAKASDNDAERPAQDKKQQKRLEAELRQKLSPLR
KQQTKLEDEQHKIASRLALIEERLADTSLYEAQNKAELTKILAERTTLGQQQEESEMAWLELQEQIDVIEQAAQL
>Mature_635_residues
MITLSQAQLIRGSKVLLDEANLTIYPGHKVGLVGANGTGKSSLLALIMGKLSLDKGDIQVPREWRIASVAQETPALEVSA
LEYVLDGDMEFRELEAALRKAETDNDGHAIADLHGKLDAIGGYSIRARAGALLAGLGFSEEKQSVSVKSFSGGWRMRLNL
AQALLCRSELLLLDEPTNHLDLDTMFWLEDWIKSYPGTLVLISHDRDFIDAIVDEIVHVENQKLNFYKGNYSTFERTRAE
RMAQQQVAFERQQRERAHMQSFVDRFRYKASKAKQAQSRLKALEKMTELLPAKADSQFYMEFREPASLPNPLVAMENVSV
GYGETPILGKVHLNLVPGARIGLLGRNGAGKSTLIKLLASELKPLTGKYEPNPGLTIGYFAQHQLEYLHMDDSPLMHLQR
LAPSHREQELRDFLGGFGFNGDMALSPVAPFSGGEKARLVLALLVWQSPNLLLLDEPTNHLDLEMRHALTLALQTFEGAM
VIVSHDRHLLRLTCNDYYLVDAGQVSSFEGDLEDYHQWLLDAAKAAAAKASDNDAERPAQDKKQQKRLEAELRQKLSPLR
KQQTKLEDEQHKIASRLALIEERLADTSLYEAQNKAELTKILAERTTLGQQQEESEMAWLELQEQIDVIEQAAQL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=518, Percent_Identity=38.996138996139, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI10947137, Length=514, Percent_Identity=37.5486381322957, Blast_Score=336, Evalue=3e-92,
Organism=Homo sapiens, GI27881506, Length=514, Percent_Identity=37.5486381322957, Blast_Score=336, Evalue=5e-92,
Organism=Homo sapiens, GI10947135, Length=539, Percent_Identity=34.3228200371057, Blast_Score=270, Evalue=3e-72,
Organism=Homo sapiens, GI69354671, Length=539, Percent_Identity=34.3228200371057, Blast_Score=270, Evalue=4e-72,
Organism=Escherichia coli, GI1789751, Length=628, Percent_Identity=60.9872611464968, Blast_Score=767, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=33.0152671755725, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI1787182, Length=637, Percent_Identity=28.2574568288854, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI2367384, Length=544, Percent_Identity=30.3308823529412, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788165, Length=207, Percent_Identity=34.7826086956522, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788506, Length=554, Percent_Identity=23.6462093862816, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787164, Length=217, Percent_Identity=29.4930875576037, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI48994883, Length=228, Percent_Identity=25.4385964912281, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=40.5660377358491, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17555318, Length=520, Percent_Identity=36.1538461538462, Blast_Score=328, Evalue=8e-90,
Organism=Caenorhabditis elegans, GI17559834, Length=543, Percent_Identity=34.4383057090239, Blast_Score=305, Evalue=6e-83,
Organism=Saccharomyces cerevisiae, GI6321121, Length=542, Percent_Identity=37.6383763837638, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6320874, Length=530, Percent_Identity=33.3962264150943, Blast_Score=297, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6325030, Length=390, Percent_Identity=32.5641025641026, Blast_Score=180, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6324314, Length=408, Percent_Identity=28.6764705882353, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6323278, Length=412, Percent_Identity=26.9417475728155, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=39.2789373814042, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24642252, Length=510, Percent_Identity=39.2156862745098, Blast_Score=358, Evalue=5e-99,
Organism=Drosophila melanogaster, GI18859989, Length=510, Percent_Identity=39.2156862745098, Blast_Score=358, Evalue=5e-99,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=35.6472795497186, Blast_Score=324, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24648279, Length=257, Percent_Identity=25.6809338521401, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161078426, Length=258, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71108; Mature: 71108

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLSQAQLIRGSKVLLDEANLTIYPGHKVGLVGANGTGKSSLLALIMGKLSLDKGDIQV
CCCCCHHHHHCCCEEEEECCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PREWRIASVAQETPALEVSALEYVLDGDMEFRELEAALRKAETDNDGHAIADLHGKLDAI
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHCC
GGYSIRARAGALLAGLGFSEEKQSVSVKSFSGGWRMRLNLAQALLCRSELLLLDEPTNHL
CCCEEHHHHCHHHCCCCCCCHHHCEEEEECCCCEEEEHHHHHHHHHHHCEEEEECCCCCC
DLDTMFWLEDWIKSYPGTLVLISHDRDFIDAIVDEIVHVENQKLNFYKGNYSTFERTRAE
CCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
RMAQQQVAFERQQRERAHMQSFVDRFRYKASKAKQAQSRLKALEKMTELLPAKADSQFYM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
EFREPASLPNPLVAMENVSVGYGETPILGKVHLNLVPGARIGLLGRNGAGKSTLIKLLAS
HHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHH
ELKPLTGKYEPNPGLTIGYFAQHQLEYLHMDDSPLMHLQRLAPSHREQELRDFLGGFGFN
HCCCCCCCCCCCCCCEEEEEHHCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCC
GDMALSPVAPFSGGEKARLVLALLVWQSPNLLLLDEPTNHLDLEMRHALTLALQTFEGAM
CCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRHLLRLTCNDYYLVDAGQVSSFEGDLEDYHQWLLDAAKAAAAKASDNDAERPAQ
EEEECCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DKKQQKRLEAELRQKLSPLRKQQTKLEDEQHKIASRLALIEERLADTSLYEAQNKAELTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAERTTLGQQQEESEMAWLELQEQIDVIEQAAQL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITLSQAQLIRGSKVLLDEANLTIYPGHKVGLVGANGTGKSSLLALIMGKLSLDKGDIQV
CCCCCHHHHHCCCEEEEECCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PREWRIASVAQETPALEVSALEYVLDGDMEFRELEAALRKAETDNDGHAIADLHGKLDAI
CCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCHHCC
GGYSIRARAGALLAGLGFSEEKQSVSVKSFSGGWRMRLNLAQALLCRSELLLLDEPTNHL
CCCEEHHHHCHHHCCCCCCCHHHCEEEEECCCCEEEEHHHHHHHHHHHCEEEEECCCCCC
DLDTMFWLEDWIKSYPGTLVLISHDRDFIDAIVDEIVHVENQKLNFYKGNYSTFERTRAE
CCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
RMAQQQVAFERQQRERAHMQSFVDRFRYKASKAKQAQSRLKALEKMTELLPAKADSQFYM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
EFREPASLPNPLVAMENVSVGYGETPILGKVHLNLVPGARIGLLGRNGAGKSTLIKLLAS
HHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHH
ELKPLTGKYEPNPGLTIGYFAQHQLEYLHMDDSPLMHLQRLAPSHREQELRDFLGGFGFN
HCCCCCCCCCCCCCCEEEEEHHCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCC
GDMALSPVAPFSGGEKARLVLALLVWQSPNLLLLDEPTNHLDLEMRHALTLALQTFEGAM
CCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRHLLRLTCNDYYLVDAGQVSSFEGDLEDYHQWLLDAAKAAAAKASDNDAERPAQ
EEEECCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DKKQQKRLEAELRQKLSPLRKQQTKLEDEQHKIASRLALIEERLADTSLYEAQNKAELTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAERTTLGQQQEESEMAWLELQEQIDVIEQAAQL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]