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The map label for this gene is ywbI [H]

Identifier: 119776060

GI number: 119776060

Start: 3482069

End: 3482959

Strand: Direct

Name: ywbI [H]

Synonym: Sama_2928

Alternate gene names: 119776060

Gene position: 3482069-3482959 (Clockwise)

Preceding gene: 119776057

Following gene: 119776064

Centisome position: 80.86

GC content: 59.93

Gene sequence:

>891_bases
TTGGATCTCAGGGCCATCAGATACTTTATGGAAGTGGTGGATGCCGGAGGCTTTGCCAAGGCCTCCGAAAAGGTCCATCT
CACCCAACCGGCGCTGTCAAAAGCAGTACGCCTGCTGGAAGAAAGCCTGGAACTGCAGCTTATCGAGCGGGGCAAGCGCG
GGGTGCATTTACGCCTCACCCCTGCCGGTGAAGTGGTCTATCGCCACGGTTTGGCCCTGCTCGCGACCCGCGACGACATG
CTGGCCGAGCTGGAAGCCATGCGAAGCCTCAGGGGCGGCCGACTCAAGTTTGGTTTGGCGCCCCTGGGCAGCGCAGAACT
GTTCGCCCCGGTCATCGCCCGCTTTCGCAGCCTCTATCCCAAGATTGATATGCAACTGCTGGTGCGCGGTGGCATTGAGC
AAACCACGGCACTGCGCAAAGGCGAAATTGAACTGGCCACCGGCATCACGGCGCTGGACAGCGAGTTTGAAGGGCTGCGC
ATTCGCAAGGACCCCATGGTAGTGGTGTTGCCGCGGCAACACTTTCTGGCCCACAGACGCGAGCTGGCGCTGCACGAACT
GGCAGACACGGCTCATATCCTGTTTGAGCCCGAATATGCCCTGCATCAGTTGGTGGTGGATGCCTGTGAACAGTCAGGCT
TCTCCCCGATTGACGTGACCCGGGTAAGCCACCCGGATTTTGGTATTGCGCTGGTGGCAGCAGGTACGGGGGCCATGATA
TTGCCAAGCTATATCGCAGAGCGCCACATGGTGGCAGGGGTTGTGAGCGTGCCGCTGAAAGAAACGGATCTGCACTGGGA
ATTGTCGCTATTTTGGCGCCGCGGCCAGCCCTTATCCTTTGCCGCCGAAGCCATGATAGCCCTGGTGAAAGAGCGCCTTG
GCGGCCTGTAA

Upstream 100 bases:

>100_bases
GGCTATCACAGTTAAAAATGGAATGTGCTTAGTGTAGATTTGCCATTTAAATAAAAAAAATGAATATTAAGCATAGATAG
CATTACCAAAGGATATCCAA

Downstream 100 bases:

>100_bases
AGTGCAAATACAACAACACCGGCGCTCAGGCCGGTGTTGATGGTTCATCGCCACTGTCGCCGATTACCAGGGTACAGTAA
GGTACAGACGGTAGAGGGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDLRAIRYFMEVVDAGGFAKASEKVHLTQPALSKAVRLLEESLELQLIERGKRGVHLRLTPAGEVVYRHGLALLATRDDM
LAELEAMRSLRGGRLKFGLAPLGSAELFAPVIARFRSLYPKIDMQLLVRGGIEQTTALRKGEIELATGITALDSEFEGLR
IRKDPMVVVLPRQHFLAHRRELALHELADTAHILFEPEYALHQLVVDACEQSGFSPIDVTRVSHPDFGIALVAAGTGAMI
LPSYIAERHMVAGVVSVPLKETDLHWELSLFWRRGQPLSFAAEAMIALVKERLGGL

Sequences:

>Translated_296_residues
MDLRAIRYFMEVVDAGGFAKASEKVHLTQPALSKAVRLLEESLELQLIERGKRGVHLRLTPAGEVVYRHGLALLATRDDM
LAELEAMRSLRGGRLKFGLAPLGSAELFAPVIARFRSLYPKIDMQLLVRGGIEQTTALRKGEIELATGITALDSEFEGLR
IRKDPMVVVLPRQHFLAHRRELALHELADTAHILFEPEYALHQLVVDACEQSGFSPIDVTRVSHPDFGIALVAAGTGAMI
LPSYIAERHMVAGVVSVPLKETDLHWELSLFWRRGQPLSFAAEAMIALVKERLGGL
>Mature_296_residues
MDLRAIRYFMEVVDAGGFAKASEKVHLTQPALSKAVRLLEESLELQLIERGKRGVHLRLTPAGEVVYRHGLALLATRDDM
LAELEAMRSLRGGRLKFGLAPLGSAELFAPVIARFRSLYPKIDMQLLVRGGIEQTTALRKGEIELATGITALDSEFEGLR
IRKDPMVVVLPRQHFLAHRRELALHELADTAHILFEPEYALHQLVVDACEQSGFSPIDVTRVSHPDFGIALVAAGTGAMI
LPSYIAERHMVAGVVSVPLKETDLHWELSLFWRRGQPLSFAAEAMIALVKERLGGL

Specific function: Transcriptional Activator Of The Hca Operon For 3- Phenylpropionic Acid Catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=30.3333333333333, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI2367136, Length=264, Percent_Identity=28.030303030303, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI157672245, Length=292, Percent_Identity=26.7123287671233, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787879, Length=288, Percent_Identity=28.125, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=23.8754325259516, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790399, Length=301, Percent_Identity=24.5847176079734, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788297, Length=147, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=32.2147651006711, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789506, Length=286, Percent_Identity=20.2797202797203, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788748, Length=305, Percent_Identity=24.2622950819672, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787530, Length=256, Percent_Identity=25, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32766; Mature: 32766

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRAIRYFMEVVDAGGFAKASEKVHLTQPALSKAVRLLEESLELQLIERGKRGVHLRLT
CCHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PAGEVVYRHGLALLATRDDMLAELEAMRSLRGGRLKFGLAPLGSAELFAPVIARFRSLYP
CCHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
KIDMQLLVRGGIEQTTALRKGEIELATGITALDSEFEGLRIRKDPMVVVLPRQHFLAHRR
CCCHHHHHHCCCHHHHHHHCCCEEEECCCHHHCCCCCCCEEECCCEEEEECCHHHHHHHH
ELALHELADTAHILFEPEYALHQLVVDACEQSGFSPIDVTRVSHPDFGIALVAAGTGAMI
HHHHHHHHCCHHEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCHH
LPSYIAERHMVAGVVSVPLKETDLHWELSLFWRRGQPLSFAAEAMIALVKERLGGL
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLRAIRYFMEVVDAGGFAKASEKVHLTQPALSKAVRLLEESLELQLIERGKRGVHLRLT
CCHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
PAGEVVYRHGLALLATRDDMLAELEAMRSLRGGRLKFGLAPLGSAELFAPVIARFRSLYP
CCHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCC
KIDMQLLVRGGIEQTTALRKGEIELATGITALDSEFEGLRIRKDPMVVVLPRQHFLAHRR
CCCHHHHHHCCCHHHHHHHCCCEEEECCCHHHCCCCCCCEEECCCEEEEECCHHHHHHHH
ELALHELADTAHILFEPEYALHQLVVDACEQSGFSPIDVTRVSHPDFGIALVAAGTGAMI
HHHHHHHHCCHHEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCHH
LPSYIAERHMVAGVVSVPLKETDLHWELSLFWRRGQPLSFAAEAMIALVKERLGGL
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]