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The map label for this gene is pdxA [H]

Identifier: 119775950

GI number: 119775950

Start: 3357585

End: 3358574

Strand: Direct

Name: pdxA [H]

Synonym: Sama_2818

Alternate gene names: 119775950

Gene position: 3357585-3358574 (Clockwise)

Preceding gene: 119775949

Following gene: 119775951

Centisome position: 77.97

GC content: 56.87

Gene sequence:

>990_bases
GTGACAGTGAAACGCATAGCCATCACCCCCGGAGAGCCTGCCGGTATAGGCCCAGATCTGGTTATTCAGCTTGCCCAGCA
AGCCTGGCCGGTACAGTTGGTGGTATGCGCCGATCCTGAGCTGCTGCACAGCCGGGCCCGTAAGTTGGGCCTGCCACTGA
CTCTGGAGCCCTATGACGCCAGCCAGCCCGCCAAACCTCAGGCGGCGGGTACCCTCACCCTGGTGCCTTTCAAGCTGAAT
GCACCGGCCGAGTGTGGCAAGCTCAATGAGCAAAACGGGCGCTATGTGGTAGATACCCTGAGCTACGCCGGCGAGAAAAA
CATGACCGGCGAGTTTGATGCCGTAGTTACGGGCCCCGTGCACAAGGGCATCATCAACCAGGCGGGCATCTCGTTCAGTG
GTCATACTGAGTTTTTTGCCAATCAGGCGGGTTGCCAGGATGTGGTGATGCTGCTGGCCTGCCCCGGTTTGCAGGTCGCG
CTGGTGACTACCCATATCCCACTGGCGTATGTGGCCAAAGCCATTACGCGAGAAAGATTACATAAAATTATCAAGATCCT
GCATCAGGATCTGGTCAGCAAGTTTGGCATTGCCTCACCCAAAATTTATGTCTGCGGCCTTAACCCCCATGCCGGGGAAG
ATGGACACCTGGGCCGCGAGGAACTGGATGTAATCATCCCAGCCCTCAATGAACTCAGGGAAGAGCTGAACTTTAATATC
GTCGGCCCGTTGCCTGCAGATACCCTGTTCCAGCCTAAATATCTGGACGATGCCGATGTGGTACTTGCCATGTACCACGA
TCAGGGATTGCCGGTACTGAAGGCACAGGGCTTTGGCAAATCCGTCAACATTACCCTTGGCCTGCCTTACATTCGCACCT
CGGTGGACCATGGTACCGCCCTGGAGCTGGCAGGTACGGGTCGCGCCGACATCGGCAGTTTTGTTTGTGCCCTCAACAAG
GCCATCGAGCTGGCTGCCAAGACCAACTGA

Upstream 100 bases:

>100_bases
GCCGTAAATTCAACGAGGAGCTGCAAGGCTGGCTCGATGAAATTCGCAGTGAAGCCCATATCGATGTGTGGGAAGCCGAA
GCTAACCGAGGTTAATCACA

Downstream 100 bases:

>100_bases
TAGAGAGTCATGAGTAATAAAGTCCACTTGGGCCATACGGCCAGAAAGCGTTTCGGTCAGAACTTCCTGACCGATGGAAA
CATTATCAACCGCATCGTAG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTVKRIAITPGEPAGIGPDLVIQLAQQAWPVQLVVCADPELLHSRARKLGLPLTLEPYDASQPAKPQAAGTLTLVPFKLN
APAECGKLNEQNGRYVVDTLSYAGEKNMTGEFDAVVTGPVHKGIINQAGISFSGHTEFFANQAGCQDVVMLLACPGLQVA
LVTTHIPLAYVAKAITRERLHKIIKILHQDLVSKFGIASPKIYVCGLNPHAGEDGHLGREELDVIIPALNELREELNFNI
VGPLPADTLFQPKYLDDADVVLAMYHDQGLPVLKAQGFGKSVNITLGLPYIRTSVDHGTALELAGTGRADIGSFVCALNK
AIELAAKTN

Sequences:

>Translated_329_residues
MTVKRIAITPGEPAGIGPDLVIQLAQQAWPVQLVVCADPELLHSRARKLGLPLTLEPYDASQPAKPQAAGTLTLVPFKLN
APAECGKLNEQNGRYVVDTLSYAGEKNMTGEFDAVVTGPVHKGIINQAGISFSGHTEFFANQAGCQDVVMLLACPGLQVA
LVTTHIPLAYVAKAITRERLHKIIKILHQDLVSKFGIASPKIYVCGLNPHAGEDGHLGREELDVIIPALNELREELNFNI
VGPLPADTLFQPKYLDDADVVLAMYHDQGLPVLKAQGFGKSVNITLGLPYIRTSVDHGTALELAGTGRADIGSFVCALNK
AIELAAKTN
>Mature_328_residues
TVKRIAITPGEPAGIGPDLVIQLAQQAWPVQLVVCADPELLHSRARKLGLPLTLEPYDASQPAKPQAAGTLTLVPFKLNA
PAECGKLNEQNGRYVVDTLSYAGEKNMTGEFDAVVTGPVHKGIINQAGISFSGHTEFFANQAGCQDVVMLLACPGLQVAL
VTTHIPLAYVAKAITRERLHKIIKILHQDLVSKFGIASPKIYVCGLNPHAGEDGHLGREELDVIIPALNELREELNFNIV
GPLPADTLFQPKYLDDADVVLAMYHDQGLPVLKAQGFGKSVNITLGLPYIRTSVDHGTALELAGTGRADIGSFVCALNKA
IELAAKTN

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=65.9509202453988, Blast_Score=442, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35200; Mature: 35069

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKRIAITPGEPAGIGPDLVIQLAQQAWPVQLVVCADPELLHSRARKLGLPLTLEPYDA
CCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEECCCCC
SQPAKPQAAGTLTLVPFKLNAPAECGKLNEQNGRYVVDTLSYAGEKNMTGEFDAVVTGPV
CCCCCCCCCCEEEEEEEECCCCHHCCCCCCCCCCEEEEEHHHCCCCCCCCCCCEEEECCH
HKGIINQAGISFSGHTEFFANQAGCQDVVMLLACPGLQVALVTTHIPLAYVAKAITRERL
HHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHH
HKIIKILHQDLVSKFGIASPKIYVCGLNPHAGEDGHLGREELDVIIPALNELREELNFNI
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
VGPLPADTLFQPKYLDDADVVLAMYHDQGLPVLKAQGFGKSVNITLGLPYIRTSVDHGTA
ECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECCCCCCE
LELAGTGRADIGSFVCALNKAIELAAKTN
EEEECCCCHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure 
TVKRIAITPGEPAGIGPDLVIQLAQQAWPVQLVVCADPELLHSRARKLGLPLTLEPYDA
CEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEECCCCC
SQPAKPQAAGTLTLVPFKLNAPAECGKLNEQNGRYVVDTLSYAGEKNMTGEFDAVVTGPV
CCCCCCCCCCEEEEEEEECCCCHHCCCCCCCCCCEEEEEHHHCCCCCCCCCCCEEEECCH
HKGIINQAGISFSGHTEFFANQAGCQDVVMLLACPGLQVALVTTHIPLAYVAKAITRERL
HHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHH
HKIIKILHQDLVSKFGIASPKIYVCGLNPHAGEDGHLGREELDVIIPALNELREELNFNI
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
VGPLPADTLFQPKYLDDADVVLAMYHDQGLPVLKAQGFGKSVNITLGLPYIRTSVDHGTA
ECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCEEEEEEECCHHEECCCCCCE
LELAGTGRADIGSFVCALNKAIELAAKTN
EEEECCCCHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]