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The map label for this gene is siaT [H]

Identifier: 119775675

GI number: 119775675

Start: 3053009

End: 3054370

Strand: Reverse

Name: siaT [H]

Synonym: Sama_2543

Alternate gene names: 119775675

Gene position: 3054370-3053009 (Counterclockwise)

Preceding gene: 119775676

Following gene: 119775674

Centisome position: 70.93

GC content: 54.04

Gene sequence:

>1362_bases
ATGGCGCTGCTGCTGTTTCTCATCATTTGTCTGGTGTTGATGCTGGGCTACCCGGTGGCACTCACCCTGGGTGGTGTGGC
CTTTTTGTTCGCCCTGTTCGCCAGTTTTTTTGGGGCTTTCGATATGGGGCTGTTTGGCCTCTTGCCCAATCGCATCTTCG
GCATTTTGAATAATCAAATTTTGATGGCGGTGCCGCTGTTTGTGTTTATGGGCGTTGTGCTTGAAAAGTCCAGGATTGCC
GAACAGTTACTCACCACCATGGGTGCACTCTTGGGGCGTTTTCGAGGCGGCCTGATTTTCAGCGTATTTTTTGTCGGCGT
GCTGCTTGCTGCCAGCACCGGCATTGTCGGTGCCACTGTGGTCACCATGGGGCTGATGTCGCTGCCAACCCTGCTTAAGC
GCGGTTACAGCCCCGAACTCAGCGCCGGTGCCATCTGCGCCACCGGCACCCTCGGGCAAATTATCCCCCCTTCCATCGCC
TTGGTGCTGCTGGGAGACGTCCTGTCCAATGCCTATCAGCAGGCTCAGCTGAAAATGGGCATTTTTAATCCCAAGTCTGT
GTCTGTGGGCGATCTCTTTGCCGGTGCTCTGATCCCGGGCTTGATGTTGGTGAGCCTCTATATGTTCTACACCCTGTTTC
GCTTATGGCGCTCTCCGGCAGATTTTGGCAGTGCGATTACGCAGGATTACGAGCCCGCGTCGCTTGCCAGGGTGATTTCA
GCTTTGTTGCCACCGCTGCTGCTGATTTTCTTGGTACTCGGCTCCATTTTGGCCGGTATTGCCACGCCAACGGAGGCGGC
GTCTGTGGGGGCCGCAGGCGCCTTGTTGATTGCGCTGCTCAAACGCCAAATGAGCATGCTGGCCTTGAAGGAGGTGATGC
AAAGCACGGTCAAAATCACATCCATGGTGTTTTTGATCCTGATTGGTGCCTCTGTGTTTTCGCTGGTCTTCAGGGGGCTT
GGCGGGGAAGAGCTGATACATAACCTCTTTGCCAATATGCCCGGTGGCGTTGTGGGTGCCATGTTACTGGTGATGACGGT
TATTTTCGTGCTCGGTTTTATCCTCGATTTTATCGAAATCACGTTTGTGGTAGTGCCACTGGTTGCGCCGATCTTGCTTG
CCATGGGGCTGGATCCTGTGTGGCTTGGGATCATGATTGCACTCAATTTGCAAACGTCCTTCTTAACCCCGCCCTTTGGT
TTTGCGCTCTTCTATTTACGGGGCGTCAGTGGAGACAGTGTTTCGAGCGGACAAATTTATCGCGGGGTGATCCCATTCGT
CATTCTGCAGTTGCTGATGTTGATATTACTTGGGATTTGGCCGGCACTTGCCACCTGGCTGCCGTCGGTTTTGTATGGCT
GA

Upstream 100 bases:

>100_bases
AAAAGTCACTGCTGCTGGGGCTGTGCGTAAGTTTGATATTGCAGGGATTGTGTGAACTTTACCGTCATGGCAAGGCGCTC
TTTGGCAGGGAGGCTTGCTG

Downstream 100 bases:

>100_bases
TGATGTCCAGGCCTGTTTAAAGGAGTAAGGAAAATGCAAACAAGATTAAGGATTTGCATGTTGATGGCCGCGAGTTTGTT
GGCCGGCTGCAATGATGATA

Product: C4 dicarboxylate ABC transporter permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MALLLFLIICLVLMLGYPVALTLGGVAFLFALFASFFGAFDMGLFGLLPNRIFGILNNQILMAVPLFVFMGVVLEKSRIA
EQLLTTMGALLGRFRGGLIFSVFFVGVLLAASTGIVGATVVTMGLMSLPTLLKRGYSPELSAGAICATGTLGQIIPPSIA
LVLLGDVLSNAYQQAQLKMGIFNPKSVSVGDLFAGALIPGLMLVSLYMFYTLFRLWRSPADFGSAITQDYEPASLARVIS
ALLPPLLLIFLVLGSILAGIATPTEAASVGAAGALLIALLKRQMSMLALKEVMQSTVKITSMVFLILIGASVFSLVFRGL
GGEELIHNLFANMPGGVVGAMLLVMTVIFVLGFILDFIEITFVVVPLVAPILLAMGLDPVWLGIMIALNLQTSFLTPPFG
FALFYLRGVSGDSVSSGQIYRGVIPFVILQLLMLILLGIWPALATWLPSVLYG

Sequences:

>Translated_453_residues
MALLLFLIICLVLMLGYPVALTLGGVAFLFALFASFFGAFDMGLFGLLPNRIFGILNNQILMAVPLFVFMGVVLEKSRIA
EQLLTTMGALLGRFRGGLIFSVFFVGVLLAASTGIVGATVVTMGLMSLPTLLKRGYSPELSAGAICATGTLGQIIPPSIA
LVLLGDVLSNAYQQAQLKMGIFNPKSVSVGDLFAGALIPGLMLVSLYMFYTLFRLWRSPADFGSAITQDYEPASLARVIS
ALLPPLLLIFLVLGSILAGIATPTEAASVGAAGALLIALLKRQMSMLALKEVMQSTVKITSMVFLILIGASVFSLVFRGL
GGEELIHNLFANMPGGVVGAMLLVMTVIFVLGFILDFIEITFVVVPLVAPILLAMGLDPVWLGIMIALNLQTSFLTPPFG
FALFYLRGVSGDSVSSGQIYRGVIPFVILQLLMLILLGIWPALATWLPSVLYG
>Mature_452_residues
ALLLFLIICLVLMLGYPVALTLGGVAFLFALFASFFGAFDMGLFGLLPNRIFGILNNQILMAVPLFVFMGVVLEKSRIAE
QLLTTMGALLGRFRGGLIFSVFFVGVLLAASTGIVGATVVTMGLMSLPTLLKRGYSPELSAGAICATGTLGQIIPPSIAL
VLLGDVLSNAYQQAQLKMGIFNPKSVSVGDLFAGALIPGLMLVSLYMFYTLFRLWRSPADFGSAITQDYEPASLARVISA
LLPPLLLIFLVLGSILAGIATPTEAASVGAAGALLIALLKRQMSMLALKEVMQSTVKITSMVFLILIGASVFSLVFRGLG
GEELIHNLFANMPGGVVGAMLLVMTVIFVLGFILDFIEITFVVVPLVAPILLAMGLDPVWLGIMIALNLQTSFLTPPFGF
ALFYLRGVSGDSVSSGQIYRGVIPFVILQLLMLILLGIWPALATWLPSVLYG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=430, Percent_Identity=24.6511627906977, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48141; Mature: 48010

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALLLFLIICLVLMLGYPVALTLGGVAFLFALFASFFGAFDMGLFGLLPNRIFGILNNQI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]