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The map label for this gene is luxS

Identifier: 119775673

GI number: 119775673

Start: 3051290

End: 3051799

Strand: Reverse

Name: luxS

Synonym: Sama_2541

Alternate gene names: 119775673

Gene position: 3051799-3051290 (Counterclockwise)

Preceding gene: 119775674

Following gene: 119775672

Centisome position: 70.87

GC content: 51.76

Gene sequence:

>510_bases
ATGCCATTATTGGACAGTTTTACCGTTGATCATACCCGCATGAACGCCCCGGCCGTGCGCGTAGCCAAGACCATGAGCAC
CCCAAAAGGTGACACCATTACCGTGTTTGACCTGCGTTTTTGTGCCCCCAATAAAGACATTCTCAGTGAGCGTGGCATCC
ACACTCTTGAGCACCTCTTCGCTGGTTTTATGCGTGATCATCTCAATGGTGAAGGTGTCGAAATTATCGATATCTCTCCC
ATGGGCTGCCGCACCGGCTTCTATATGAGCCTGATTGGCGAACCGGCTGAAAAGCGCGTGGCGGACGCCTGGCTGGCTGC
CATGGAAGATGTACTGAATGTGGTTGATCAAAAGGCCATCCCTGAGCTCAACGAATATCAGTGCGGCACTTACGAGATGC
ACTCACTGTCTCAGGCGCAGGACATTGCCAAAGCCGTGATTGCTGCCGGGATCAGTGTGAACCGCAACGACGAACTTAAA
CTGTCAGACGAAATTTTGCACAAACTCTAA

Upstream 100 bases:

>100_bases
CCGTTTACGTGAATGAGTTTTGGTGGCCCTGCTTTGATGCTATGCTTGCGTCACTTTGCACCACCCAATTGTGCCCCAAC
AGAAGGGGCTGGAGAGCAAC

Downstream 100 bases:

>100_bases
TTTCTCTGACATAACGTCAAAAAAGCGGCGCCAGCCGCTTTTTTTTCGTCTAAAATCATCCATGTCACAAAAAAATTACA
AATAAACCACCCCAGGTGGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPLLDSFTVDHTRMNAPAVRVAKTMSTPKGDTITVFDLRFCAPNKDILSERGIHTLEHLFAGFMRDHLNGEGVEIIDISP
MGCRTGFYMSLIGEPAEKRVADAWLAAMEDVLNVVDQKAIPELNEYQCGTYEMHSLSQAQDIAKAVIAAGISVNRNDELK
LSDEILHKL

Sequences:

>Translated_169_residues
MPLLDSFTVDHTRMNAPAVRVAKTMSTPKGDTITVFDLRFCAPNKDILSERGIHTLEHLFAGFMRDHLNGEGVEIIDISP
MGCRTGFYMSLIGEPAEKRVADAWLAAMEDVLNVVDQKAIPELNEYQCGTYEMHSLSQAQDIAKAVIAAGISVNRNDELK
LSDEILHKL
>Mature_168_residues
PLLDSFTVDHTRMNAPAVRVAKTMSTPKGDTITVFDLRFCAPNKDILSERGIHTLEHLFAGFMRDHLNGEGVEIIDISPM
GCRTGFYMSLIGEPAEKRVADAWLAAMEDVLNVVDQKAIPELNEYQCGTYEMHSLSQAQDIAKAVIAAGISVNRNDELKL
SDEILHKL

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=169, Percent_Identity=75.7396449704142, Blast_Score=279, Evalue=9e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_SHEAM (A1S8N7)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928413.1
- ProteinModelPortal:   A1S8N7
- SMR:   A1S8N7
- STRING:   A1S8N7
- GeneID:   4604788
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2541
- NMPDR:   fig|326297.7.peg.2381
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- PhylomeDB:   A1S8N7
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18731; Mature: 18600

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMNAPAVRVAKTMSTPKGDTITVFDLRFCAPNKDILSERGIHTLEHLF
CCCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRDHLNGEGVEIIDISPMGCRTGFYMSLIGEPAEKRVADAWLAAMEDVLNVVDQKAI
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PELNEYQCGTYEMHSLSQAQDIAKAVIAAGISVNRNDELKLSDEILHKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
PLLDSFTVDHTRMNAPAVRVAKTMSTPKGDTITVFDLRFCAPNKDILSERGIHTLEHLF
CCCCCCCCCCHHCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCHHHHHHHH
AGFMRDHLNGEGVEIIDISPMGCRTGFYMSLIGEPAEKRVADAWLAAMEDVLNVVDQKAI
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PELNEYQCGTYEMHSLSQAQDIAKAVIAAGISVNRNDELKLSDEILHKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA