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The map label for this gene is cirA [H]

Identifier: 119775527

GI number: 119775527

Start: 2873783

End: 2876383

Strand: Reverse

Name: cirA [H]

Synonym: Sama_2393

Alternate gene names: 119775527

Gene position: 2876383-2873783 (Counterclockwise)

Preceding gene: 119775529

Following gene: 119775526

Centisome position: 66.8

GC content: 56.36

Gene sequence:

>2601_bases
ATGAAAGTTTCAGTATTTGCCTGCGCCATTTCCGGTTTTGCCCTGTCAGCCCTGACCATCGCCATGGCCCACGCGGCCGA
TGACGACAAGGCTATTTCAGCCGAATCCAAACTCGAAAAAATCCAGATCACCGGTTCACGCCTGAAAGGGGTGGACATGG
AAGGGGCCAATCCACTGCAGTCATTCGATCAGGAAGAACTGGTCAAGCGGGGCTATGACACCATTGCCGAATTCCTCAAG
GACCTGCCCCAGGCGGCAAGTGCCGGCACCTTTACCGAAACCGGTGGCGTGGGCGGCGCCGATGGCGCGCCGGCAGGGGC
TGCCGGGGTAAGTTTGCGTGGGCTGGGTTCAAGTTCAACGCTGGTGCTGGTCAATGGTCGCCGGGTGGCGGTGGACTCCT
TCTCCAATGGCTCTGACTCCTTTGTGAACGTTAACGCCATTCCCATGGCAGCCATTGAGCGCATCGATGTGCTGACCGAT
GGCGCTTCGTCCATTTATGGATCAGACGCCATCGCTGGAGTGATTAACTTTATTCTGCGTAAGGATTTTGTCGGGCATGA
ACTGACGGCCCAGTACGGTAATGACACCAGTGACCATGACGCCAGTCGCACCGGGCTGACCTATGCCGGCGGCTTTGCCA
CCGACAATACCAACACCACAGTGGTGCTGGATTACGCCAAGCGCAACGCGATTTTCAACAGCGATCGCCCCATCAAGGTA
ACTTACACCTCCTACACCGAGATGGTGATTGATGGCAATTATTACGCCGAAGACTGGTGTGGTGACGATACCCGCTGGGG
TGGTGAAGCCTGTAACTATGACTACGTAATCCAGCGCGCCATTCAACCGGATTTTGAGAACCTTGGCGCCACCTTGAATC
ATCAGTGGCAGCTGGACAATGACATGACCTTTTTTGCCGAGGCCATGTATCAGCAAAACACCGGCCATGCCTATGAAGCG
CCAGCAGGTTACACGGTGACAGTCCCGGGGGATGCGGCTTACGTGCCTGGCTATGTGCGTGACATCAACGCCGCAGACGG
CGATGACAGCAACAGCATCAGGGTTCGTACCCGTATGCCAGAGCGCAGAATTCAGGAATACGATACCGAAAGCTATAGAG
TTTTGGCCGGTCTTCGCGGCGAGTGGGGCGACTGGGGTTGGGAGTCAGCAGCAAGCTATGGCAAGTCCACCAACGAAGTG
ACCCATGTGGCGGGCTATATGAATCGCGATGCCCTGGCCGATGCCATTGCGAGCGGCAGTTTCAACCCTTTTAACCTGGG
GATGGACAACAGTGAGGAGGCGATTGCGGCGCTGCGTGACAGTGCCATTCGCCGCGGTGAGTCTGAGGTGATGTCCCTGG
ATGCCAACATCAGTGGTGAACTCTTTGAGATGGATGCCGGTTTGGTGAGCGCCGTATTTGGCGCCGAACTTCGCAGTGAA
GAGATAGTGGATAATCCGGCTGCATCAGCGGTAAACGACGATGTAATAGGTCTTGGCGCCAGTGATGCGGCCGCCGACAG
GACCCAGTATGCCCTGTATGGCGAGATTAATCTGCCGCTGTTTGAGGGACTGGACCTGATAACCGCGCTGCGGTACGACC
ACTACAGTGATTTTGGTGGCGACATCAATCCCAAGGTATCGCTGCGCTATAAGGCGACCGACGATCTGGTGCTCAGAGCA
TCCTGGAGCACGGGTTTCCGGGCACCGTCGCTTTCACAGCTCGGTGCAGGCACCTCCCTTGGCAGTCAATACATTAACTG
CGGCGCAGGTGAGCCTTTCAATGCCCTGTGTGGCACCAATGGTGCCATCGATGGTGAGCTGGAGTTCGATCAGGAAACCA
TAGGTAACAAGGGGTTGGATGCCGAATCTTCGGAAGCCATCAACGCTGGACTGTCGTGGAATTTGACCGACAACTGGCAG
CTTACCGTGGATTACTGGCGCTACGATCACGAAGACATAGTGGATATCGATGCTTCCACCACTCTCAATGCCTGCGTAAA
AGGCACTGCGCCTGTTGTGGGTTCAGTGAGCGAGCTTAAGGGCGAGTTTGGTTGTGTAATTGATGGCAACGGCGATATCA
GCTTCCTGCGTACCGGCTACTTTAACGTTGGCAGCCAAACCACAGATGGTCTTGACTATCGCATGACCTATCGTCTTGAG
ACAGCCGCGGCAGGTGAGTTCAGTTTCTACGTCAGCGGCACCGAAACCTTCAGCTTTGAGCGTCAGGTGACTCCGGATGC
CGACGTAGAGGACCTCCTTGGCCGCTTGTCCGGTGCCAACGAAATCGCCCGACCTGAGCGGGTGCTGGATGCCGGTACGG
ACTGGAGCCTGGGTGATTGGAGTGCCAGCCTCAGCGCTCATTACGTCTCCAGCATGGGCGATGGTGACTTCAGGTTTGAT
AACGAGACGGTGGACAGCTGGCTTACCTTCAGTGCCAGTGTGGGTGTGACCCTGATGGAGAATCACTCGCTGATGTTGTC
GGTTCGTAACCTTACCGATGAGGAGCCGCCATACGCGTCGTCGCCCACCAATGGTTACGCCAGCTCGGCCCATGACTGGC
TCGGTCAGCGCTGGAACCTGCGTTATAGCCTGCGCTTCTGA

Upstream 100 bases:

>100_bases
TGCACCGTGAACGCACAACTTTTTTGTGCCACGTATTGACCACGTTCGGTTGCTTTGGTGCGCGCCTGAAAAATTATTCG
CATATTTTTGGGAGCTTCTC

Downstream 100 bases:

>100_bases
TGTTCTCCCTGGCCGGGCTTGCCCGGCCATTTTTCATTGTGGGAGGACCTATGTCTTTATCCAAACGGGAAATGCCGGAT
GCCTTCATCATCCTGATGTT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 866

Protein sequence:

>866_residues
MKVSVFACAISGFALSALTIAMAHAADDDKAISAESKLEKIQITGSRLKGVDMEGANPLQSFDQEELVKRGYDTIAEFLK
DLPQAASAGTFTETGGVGGADGAPAGAAGVSLRGLGSSSTLVLVNGRRVAVDSFSNGSDSFVNVNAIPMAAIERIDVLTD
GASSIYGSDAIAGVINFILRKDFVGHELTAQYGNDTSDHDASRTGLTYAGGFATDNTNTTVVLDYAKRNAIFNSDRPIKV
TYTSYTEMVIDGNYYAEDWCGDDTRWGGEACNYDYVIQRAIQPDFENLGATLNHQWQLDNDMTFFAEAMYQQNTGHAYEA
PAGYTVTVPGDAAYVPGYVRDINAADGDDSNSIRVRTRMPERRIQEYDTESYRVLAGLRGEWGDWGWESAASYGKSTNEV
THVAGYMNRDALADAIASGSFNPFNLGMDNSEEAIAALRDSAIRRGESEVMSLDANISGELFEMDAGLVSAVFGAELRSE
EIVDNPAASAVNDDVIGLGASDAAADRTQYALYGEINLPLFEGLDLITALRYDHYSDFGGDINPKVSLRYKATDDLVLRA
SWSTGFRAPSLSQLGAGTSLGSQYINCGAGEPFNALCGTNGAIDGELEFDQETIGNKGLDAESSEAINAGLSWNLTDNWQ
LTVDYWRYDHEDIVDIDASTTLNACVKGTAPVVGSVSELKGEFGCVIDGNGDISFLRTGYFNVGSQTTDGLDYRMTYRLE
TAAAGEFSFYVSGTETFSFERQVTPDADVEDLLGRLSGANEIARPERVLDAGTDWSLGDWSASLSAHYVSSMGDGDFRFD
NETVDSWLTFSASVGVTLMENHSLMLSVRNLTDEEPPYASSPTNGYASSAHDWLGQRWNLRYSLRF

Sequences:

>Translated_866_residues
MKVSVFACAISGFALSALTIAMAHAADDDKAISAESKLEKIQITGSRLKGVDMEGANPLQSFDQEELVKRGYDTIAEFLK
DLPQAASAGTFTETGGVGGADGAPAGAAGVSLRGLGSSSTLVLVNGRRVAVDSFSNGSDSFVNVNAIPMAAIERIDVLTD
GASSIYGSDAIAGVINFILRKDFVGHELTAQYGNDTSDHDASRTGLTYAGGFATDNTNTTVVLDYAKRNAIFNSDRPIKV
TYTSYTEMVIDGNYYAEDWCGDDTRWGGEACNYDYVIQRAIQPDFENLGATLNHQWQLDNDMTFFAEAMYQQNTGHAYEA
PAGYTVTVPGDAAYVPGYVRDINAADGDDSNSIRVRTRMPERRIQEYDTESYRVLAGLRGEWGDWGWESAASYGKSTNEV
THVAGYMNRDALADAIASGSFNPFNLGMDNSEEAIAALRDSAIRRGESEVMSLDANISGELFEMDAGLVSAVFGAELRSE
EIVDNPAASAVNDDVIGLGASDAAADRTQYALYGEINLPLFEGLDLITALRYDHYSDFGGDINPKVSLRYKATDDLVLRA
SWSTGFRAPSLSQLGAGTSLGSQYINCGAGEPFNALCGTNGAIDGELEFDQETIGNKGLDAESSEAINAGLSWNLTDNWQ
LTVDYWRYDHEDIVDIDASTTLNACVKGTAPVVGSVSELKGEFGCVIDGNGDISFLRTGYFNVGSQTTDGLDYRMTYRLE
TAAAGEFSFYVSGTETFSFERQVTPDADVEDLLGRLSGANEIARPERVLDAGTDWSLGDWSASLSAHYVSSMGDGDFRFD
NETVDSWLTFSASVGVTLMENHSLMLSVRNLTDEEPPYASSPTNGYASSAHDWLGQRWNLRYSLRF
>Mature_866_residues
MKVSVFACAISGFALSALTIAMAHAADDDKAISAESKLEKIQITGSRLKGVDMEGANPLQSFDQEELVKRGYDTIAEFLK
DLPQAASAGTFTETGGVGGADGAPAGAAGVSLRGLGSSSTLVLVNGRRVAVDSFSNGSDSFVNVNAIPMAAIERIDVLTD
GASSIYGSDAIAGVINFILRKDFVGHELTAQYGNDTSDHDASRTGLTYAGGFATDNTNTTVVLDYAKRNAIFNSDRPIKV
TYTSYTEMVIDGNYYAEDWCGDDTRWGGEACNYDYVIQRAIQPDFENLGATLNHQWQLDNDMTFFAEAMYQQNTGHAYEA
PAGYTVTVPGDAAYVPGYVRDINAADGDDSNSIRVRTRMPERRIQEYDTESYRVLAGLRGEWGDWGWESAASYGKSTNEV
THVAGYMNRDALADAIASGSFNPFNLGMDNSEEAIAALRDSAIRRGESEVMSLDANISGELFEMDAGLVSAVFGAELRSE
EIVDNPAASAVNDDVIGLGASDAAADRTQYALYGEINLPLFEGLDLITALRYDHYSDFGGDINPKVSLRYKATDDLVLRA
SWSTGFRAPSLSQLGAGTSLGSQYINCGAGEPFNALCGTNGAIDGELEFDQETIGNKGLDAESSEAINAGLSWNLTDNWQ
LTVDYWRYDHEDIVDIDASTTLNACVKGTAPVVGSVSELKGEFGCVIDGNGDISFLRTGYFNVGSQTTDGLDYRMTYRLE
TAAAGEFSFYVSGTETFSFERQVTPDADVEDLLGRLSGANEIARPERVLDAGTDWSLGDWSASLSAHYVSSMGDGDFRFD
NETVDSWLTFSASVGVTLMENHSLMLSVRNLTDEEPPYASSPTNGYASSAHDWLGQRWNLRYSLRF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=203, Percent_Identity=31.5270935960591, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790405, Length=221, Percent_Identity=23.5294117647059, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 93368; Mature: 93368

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSVFACAISGFALSALTIAMAHAADDDKAISAESKLEKIQITGSRLKGVDMEGANPLQ
CEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEECCCCCCCCCCCCCHHH
SFDQEELVKRGYDTIAEFLKDLPQAASAGTFTETGGVGGADGAPAGAAGVSLRGLGSSST
HCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
LVLVNGRRVAVDSFSNGSDSFVNVNAIPMAAIERIDVLTDGASSIYGSDAIAGVINFILR
EEEECCCEEEEECCCCCCCCEEEEECCCHHHHHHHHEEECCCHHHCCCHHHHHHHHHHHH
KDFVGHELTAQYGNDTSDHDASRTGLTYAGGFATDNTNTTVVLDYAKRNAIFNSDRPIKV
HCCCCCEEEHHCCCCCCCCCCCCCCCEEECCEEECCCCCEEEEEECCCCCEECCCCCEEE
TYTSYTEMVIDGNYYAEDWCGDDTRWGGEACNYDYVIQRAIQPDFENLGATLNHQWQLDN
EEECEEEEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCEEEECC
DMTFFAEAMYQQNTGHAYEAPAGYTVTVPGDAAYVPGYVRDINAADGDDSNSIRVRTRMP
CHHHHHHHHHHCCCCCCEECCCCCEEECCCCCCCCCCHHEECCCCCCCCCCEEEEEECCC
ERRIQEYDTESYRVLAGLRGEWGDWGWESAASYGKSTNEVTHVAGYMNRDALADAIASGS
HHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCC
FNPFNLGMDNSEEAIAALRDSAIRRGESEVMSLDANISGELFEMDAGLVSAVFGAELRSE
CCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECHHHHHHHHHHHHCCH
EIVDNPAASAVNDDVIGLGASDAAADRTQYALYGEINLPLFEGLDLITALRYDHYSDFGG
HHHCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCC
DINPKVSLRYKATDDLVLRASWSTGFRAPSLSQLGAGTSLGSQYINCGAGEPFNALCGTN
CCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHCCCCCCCHHHEECCCCCCCHHHCCCC
GAIDGELEFDQETIGNKGLDAESSEAINAGLSWNLTDNWQLTVDYWRYDHEDIVDIDAST
CCCCCEEECCHHHCCCCCCCCCCCHHHCCCEEECCCCCEEEEEEEEECCCCCEEECCCCC
TLNACVKGTAPVVGSVSELKGEFGCVIDGNGDISFLRTGYFNVGSQTTDGLDYRMTYRLE
HHHHHHCCCCCCCCCHHHHCCCCCEEEECCCCEEEEEECCEECCCCCCCCCCEEEEEEEE
TAAAGEFSFYVSGTETFSFERQVTPDADVEDLLGRLSGANEIARPERVLDAGTDWSLGDW
ECCCCCEEEEEECCEEEEEEECCCCCCCHHHHHHHHCCCCHHCCCHHHHCCCCCCCCCCC
SASLSAHYVSSMGDGDFRFDNETVDSWLTFSASVGVTLMENHSLMLSVRNLTDEEPPYAS
CHHHHHHHHHHCCCCCEEECCHHHHHHEEEECCCCEEEEECCEEEEEEECCCCCCCCCCC
SPTNGYASSAHDWLGQRWNLRYSLRF
CCCCCCCCCHHHHHCCCCCEEEEEEC
>Mature Secondary Structure
MKVSVFACAISGFALSALTIAMAHAADDDKAISAESKLEKIQITGSRLKGVDMEGANPLQ
CEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEEECCCCCCCCCCCCCHHH
SFDQEELVKRGYDTIAEFLKDLPQAASAGTFTETGGVGGADGAPAGAAGVSLRGLGSSST
HCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
LVLVNGRRVAVDSFSNGSDSFVNVNAIPMAAIERIDVLTDGASSIYGSDAIAGVINFILR
EEEECCCEEEEECCCCCCCCEEEEECCCHHHHHHHHEEECCCHHHCCCHHHHHHHHHHHH
KDFVGHELTAQYGNDTSDHDASRTGLTYAGGFATDNTNTTVVLDYAKRNAIFNSDRPIKV
HCCCCCEEEHHCCCCCCCCCCCCCCCEEECCEEECCCCCEEEEEECCCCCEECCCCCEEE
TYTSYTEMVIDGNYYAEDWCGDDTRWGGEACNYDYVIQRAIQPDFENLGATLNHQWQLDN
EEECEEEEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCEEEECC
DMTFFAEAMYQQNTGHAYEAPAGYTVTVPGDAAYVPGYVRDINAADGDDSNSIRVRTRMP
CHHHHHHHHHHCCCCCCEECCCCCEEECCCCCCCCCCHHEECCCCCCCCCCEEEEEECCC
ERRIQEYDTESYRVLAGLRGEWGDWGWESAASYGKSTNEVTHVAGYMNRDALADAIASGS
HHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCC
FNPFNLGMDNSEEAIAALRDSAIRRGESEVMSLDANISGELFEMDAGLVSAVFGAELRSE
CCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECHHHHHHHHHHHHCCH
EIVDNPAASAVNDDVIGLGASDAAADRTQYALYGEINLPLFEGLDLITALRYDHYSDFGG
HHHCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCC
DINPKVSLRYKATDDLVLRASWSTGFRAPSLSQLGAGTSLGSQYINCGAGEPFNALCGTN
CCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHCCCCCCCHHHEECCCCCCCHHHCCCC
GAIDGELEFDQETIGNKGLDAESSEAINAGLSWNLTDNWQLTVDYWRYDHEDIVDIDAST
CCCCCEEECCHHHCCCCCCCCCCCHHHCCCEEECCCCCEEEEEEEEECCCCCEEECCCCC
TLNACVKGTAPVVGSVSELKGEFGCVIDGNGDISFLRTGYFNVGSQTTDGLDYRMTYRLE
HHHHHHCCCCCCCCCHHHHCCCCCEEEECCCCEEEEEECCEECCCCCCCCCCEEEEEEEE
TAAAGEFSFYVSGTETFSFERQVTPDADVEDLLGRLSGANEIARPERVLDAGTDWSLGDW
ECCCCCEEEEEECCEEEEEEECCCCCCCHHHHHHHHCCCCHHCCCHHHHCCCCCCCCCCC
SASLSAHYVSSMGDGDFRFDNETVDSWLTFSASVGVTLMENHSLMLSVRNLTDEEPPYAS
CHHHHHHHHHHCCCCCEEECCHHHHHHEEEECCCCEEEEECCEEEEEEECCCCCCCCCCC
SPTNGYASSAHDWLGQRWNLRYSLRF
CCCCCCCCCHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]