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The map label for this gene is xseA

Identifier: 119775494

GI number: 119775494

Start: 2835793

End: 2837136

Strand: Direct

Name: xseA

Synonym: Sama_2360

Alternate gene names: 119775494

Gene position: 2835793-2837136 (Clockwise)

Preceding gene: 119775491

Following gene: 119775503

Centisome position: 65.85

GC content: 58.11

Gene sequence:

>1344_bases
ATGCAAGTCCCTAAAAATGATGTTTATACCGTGTCCCGCCTCAACGGCGAAGTACGGCAACTTCTGGAGGGACAGTTGGG
GCGGATTTGGCTGACCGGCGAGATCTCCAATTTCTCTTCTCCTTCATCCGGCCACTGGTACCTCACCCTCAAAGACAGCC
ATTCGCAGCTGCGCTGTGCCATGTTCAAGGGGCGTAACACCACAGTGGCATTCAAGCCCATCAACGGCCAGCAGGTGTTG
GTGCGTGGCAGTATCAGCGTGTATGAACCCAGAGGCGACTATCAGCTGCTGATTGAAGCCATGTTCCCCGCTGGGGATGG
CTTGCTGGCGGCCCAGTTTGAAGCCCTGAAGATGAAACTTGCCGCCGAAGGTTTGTTTGCCCAGGACACCAAGCGGCCGC
TGCCCGAGTCAATTCAGCGCATTGGGGTTATCACCTCCCCAACAGGCGCGGCCATCCGCGATGTGCTCCATGTGCTGAAA
AGACGTGACCCAAGCGTGGAGGTAGTAATTTACCCCACGGCAGTTCAGGGCACCGGCGCCGACAAAGACATCATTCGTGC
CATCGAGCTTGCCAACCAGAGGCTTGAAGTGGATGTGCTCCTGCTCACCCGGGGAGGCGGGAGCCTCGAAGACCTCTGGT
GCTTCAACAGCGAAGCCCTTGCTCACGCCATCTACAACAGCACCCTGACCATAGTGAGCGCGGTGGGCCATGAGGTAGAT
ACCAGCATTGCCGACTTTGTCGCCGATGTCAGAGCACCGACGCCTTCTGCGGGCGCCGAGCTGCTGTCGGGAGACCAAAG
CCACAAGCAGCAAAAACTCGCCGGTGCCCTTGCCAGACTGACCCAGGGCTGGCGCCATTACGCCCTTAAACGTCATTCCG
GTCTGATTTCACTGCAATCCCGGCTCGACCGGCAAGATCCTAAACGCCAGTTACAGCAGCAGTCCCAGCGCCTCGATGAG
TTGGAACTGCGGCTGACATCCAGTATTCAGAGACGCCTATCGTCCCACACGCTTACCACAGAGCGGTTAAAGGCAAGGCT
CGAACGCCACTCACCGGCCCAGCGCTTGATGATGGAACAGCAGCGGCTCACTTACCTCGATGAAAGACTCAAGGGCGCCA
TGGAAGACAGGCTGGAAGATGCGCAAACACACCTTGGGGGGCTCAGCCACTCACTCGCCAGCGTGTCTCCACTGGCGACC
TTAAGCCGCGGCTACTCCATCACCCGAGACGCTGGTGGCAGGGTACTGACTCAGGCGAGCAGCATGAAAACCGGCGATAC
CATAGAGACTCAACTGGAACAGGGTTCACTTTTGGCCCGCGTCATTGAGATCAAGCCGGAGTAA

Upstream 100 bases:

>100_bases
AGGATAAGTAGAGGTGAAATATTGCGGCGGCATTATACCTTGCAAGTGAGGGTCGGTAAATGCAAAATTGTGAAAAATTA
CCATTTGCCCGGAATTTTCA

Downstream 100 bases:

>100_bases
CACAATCCAAAGCCGGGGAGTAAAGATTTTCATGCCCGCGAAGAGCATAAAAAAGCCAGGCATATGCCCGGCTTTTTTAT
TGACGCTTCAGTCCGACTGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MQVPKNDVYTVSRLNGEVRQLLEGQLGRIWLTGEISNFSSPSSGHWYLTLKDSHSQLRCAMFKGRNTTVAFKPINGQQVL
VRGSISVYEPRGDYQLLIEAMFPAGDGLLAAQFEALKMKLAAEGLFAQDTKRPLPESIQRIGVITSPTGAAIRDVLHVLK
RRDPSVEVVIYPTAVQGTGADKDIIRAIELANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHAIYNSTLTIVSAVGHEVD
TSIADFVADVRAPTPSAGAELLSGDQSHKQQKLAGALARLTQGWRHYALKRHSGLISLQSRLDRQDPKRQLQQQSQRLDE
LELRLTSSIQRRLSSHTLTTERLKARLERHSPAQRLMMEQQRLTYLDERLKGAMEDRLEDAQTHLGGLSHSLASVSPLAT
LSRGYSITRDAGGRVLTQASSMKTGDTIETQLEQGSLLARVIEIKPE

Sequences:

>Translated_447_residues
MQVPKNDVYTVSRLNGEVRQLLEGQLGRIWLTGEISNFSSPSSGHWYLTLKDSHSQLRCAMFKGRNTTVAFKPINGQQVL
VRGSISVYEPRGDYQLLIEAMFPAGDGLLAAQFEALKMKLAAEGLFAQDTKRPLPESIQRIGVITSPTGAAIRDVLHVLK
RRDPSVEVVIYPTAVQGTGADKDIIRAIELANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHAIYNSTLTIVSAVGHEVD
TSIADFVADVRAPTPSAGAELLSGDQSHKQQKLAGALARLTQGWRHYALKRHSGLISLQSRLDRQDPKRQLQQQSQRLDE
LELRLTSSIQRRLSSHTLTTERLKARLERHSPAQRLMMEQQRLTYLDERLKGAMEDRLEDAQTHLGGLSHSLASVSPLAT
LSRGYSITRDAGGRVLTQASSMKTGDTIETQLEQGSLLARVIEIKPE
>Mature_447_residues
MQVPKNDVYTVSRLNGEVRQLLEGQLGRIWLTGEISNFSSPSSGHWYLTLKDSHSQLRCAMFKGRNTTVAFKPINGQQVL
VRGSISVYEPRGDYQLLIEAMFPAGDGLLAAQFEALKMKLAAEGLFAQDTKRPLPESIQRIGVITSPTGAAIRDVLHVLK
RRDPSVEVVIYPTAVQGTGADKDIIRAIELANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHAIYNSTLTIVSAVGHEVD
TSIADFVADVRAPTPSAGAELLSGDQSHKQQKLAGALARLTQGWRHYALKRHSGLISLQSRLDRQDPKRQLQQQSQRLDE
LELRLTSSIQRRLSSHTLTTERLKARLERHSPAQRLMMEQQRLTYLDERLKGAMEDRLEDAQTHLGGLSHSLASVSPLAT
LSRGYSITRDAGGRVLTQASSMKTGDTIETQLEQGSLLARVIEIKPE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=439, Percent_Identity=48.74715261959, Blast_Score=430, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_SHEAM (A1S858)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928234.1
- STRING:   A1S858
- GeneID:   4604609
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2360
- NMPDR:   fig|326297.7.peg.2210
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   EISNFTR
- PhylomeDB:   A1S858
- ProtClustDB:   PRK00286
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 49409; Mature: 49409

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVPKNDVYTVSRLNGEVRQLLEGQLGRIWLTGEISNFSSPSSGHWYLTLKDSHSQLRCA
CCCCCCCCEEHHHCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEE
MFKGRNTTVAFKPINGQQVLVRGSISVYEPRGDYQLLIEAMFPAGDGLLAAQFEALKMKL
EECCCCCEEEEEECCCCEEEEECCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFAQDTKRPLPESIQRIGVITSPTGAAIRDVLHVLKRRDPSVEVVIYPTAVQGTGA
HHCCCHHCCCCCCCHHHHHHCCCEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCC
DKDIIRAIELANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHAIYNSTLTIVSAVGHEVD
CHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHCCHHH
TSIADFVADVRAPTPSAGAELLSGDQSHKQQKLAGALARLTQGWRHYALKRHSGLISLQS
HHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RLDRQDPKRQLQQQSQRLDELELRLTSSIQRRLSSHTLTTERLKARLERHSPAQRLMMEQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHH
QRLTYLDERLKGAMEDRLEDAQTHLGGLSHSLASVSPLATLSRGYSITRDAGGRVLTQAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECC
SMKTGDTIETQLEQGSLLARVIEIKPE
CCCCCCHHHHHHHHCHHEEHHEEECCC
>Mature Secondary Structure
MQVPKNDVYTVSRLNGEVRQLLEGQLGRIWLTGEISNFSSPSSGHWYLTLKDSHSQLRCA
CCCCCCCCEEHHHCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEE
MFKGRNTTVAFKPINGQQVLVRGSISVYEPRGDYQLLIEAMFPAGDGLLAAQFEALKMKL
EECCCCCEEEEEECCCCEEEEECCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFAQDTKRPLPESIQRIGVITSPTGAAIRDVLHVLKRRDPSVEVVIYPTAVQGTGA
HHCCCHHCCCCCCCHHHHHHCCCEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCC
DKDIIRAIELANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHAIYNSTLTIVSAVGHEVD
CHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHCCHHH
TSIADFVADVRAPTPSAGAELLSGDQSHKQQKLAGALARLTQGWRHYALKRHSGLISLQS
HHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RLDRQDPKRQLQQQSQRLDELELRLTSSIQRRLSSHTLTTERLKARLERHSPAQRLMMEQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHH
QRLTYLDERLKGAMEDRLEDAQTHLGGLSHSLASVSPLATLSRGYSITRDAGGRVLTQAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECC
SMKTGDTIETQLEQGSLLARVIEIKPE
CCCCCCHHHHHHHHCHHEEHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA