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The map label for this gene is cysQ [H]

Identifier: 119775367

GI number: 119775367

Start: 2696411

End: 2697256

Strand: Reverse

Name: cysQ [H]

Synonym: Sama_2232

Alternate gene names: 119775367

Gene position: 2697256-2696411 (Counterclockwise)

Preceding gene: 119775368

Following gene: 119775366

Centisome position: 62.64

GC content: 57.21

Gene sequence:

>846_bases
ATGGCGGTTTTTGCTTGGCCAGAACATCACGGACCACAGGTTGCAGGAGGATATATGACATTGGTGGCATTGGATAAAAC
GACACTGGATAAGCTGGGGCAGATAGCCCGTCAGGCTGGTGCGGCCATAATGGCAGTGTACGGGCAGGGTGACGTGGCCG
TGACTCAGAAAAGCGACGACAGCCCGGTGACTGCCGCTGATTTGGCCAGCCATACCGTGATAATCGAGCAGCTCGCTGCG
GCCTTTCCGTTTACACCGGTGCTGTCAGAAGAGGCCGTTATTGACTGGGAAACCCGCCGTCAGTGGCAGGAGTACTTCCT
TATCGATCCCCTCGATGGCACCAAGGAGTTTATCAAGCGCAATGGTGAGTTTACCGTCAATATTGCGCTGGTGAGAGATG
GCATTGCCGTAGCCGGTGTGGTGTTTGCCCCCGTCCTGGATACCTGTTATCTCGGAGCAGAGGGACTGGGCGCCTGGCTC
GAGTGTCAGGGAAAGCAGCAACCATTGCAGGGTAGTGCGCAAAAACGCGACGTTCCCGTGGTTGTTGGCAGTCGCTCACA
TCAGTCTGCCGAGATGGCGGGTTATTTGGCCGACCTTGGCGACCATGAGCTTCTCAGTGTGGGCAGCTCGCTTAAATTTT
GCATGCTTGCCGAAGGGCGGGCAGACCTGTACCCGCGTCTTGGGCCAACCAGCGAGTGGGACACGGCAGCTGCCCAGGCG
GTGCTGGAGAGCGCCGGGGGCAGGGTGGTGGTGTATGGCGAGTCCAACCCGCTGGTTTACAACAAAAAAGAACAGCTTCT
TAACCCTTGGTTTATGGCAACTGCCCCGGGGTGGAACACTCATTAA

Upstream 100 bases:

>100_bases
GCCTCAGGCAGGTCTTTTCTCAGAGCAGGTGCTGCCTTAGTATCTTTGGCACTGAATTTAACGAAATTGTTATTATTTCC
TACCGGGTGCCAGTGGCATA

Downstream 100 bases:

>100_bases
CAGCCCAGGCTGAAATGGAGAAAGCAGATGATGCGAATGGGGGTGGATCTCGGTGGCACCAAGATTGAGCTGGTGGCCTT
GGGAGAAGATGGCAGTGAGC

Product: cysQ protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MAVFAWPEHHGPQVAGGYMTLVALDKTTLDKLGQIARQAGAAIMAVYGQGDVAVTQKSDDSPVTAADLASHTVIIEQLAA
AFPFTPVLSEEAVIDWETRRQWQEYFLIDPLDGTKEFIKRNGEFTVNIALVRDGIAVAGVVFAPVLDTCYLGAEGLGAWL
ECQGKQQPLQGSAQKRDVPVVVGSRSHQSAEMAGYLADLGDHELLSVGSSLKFCMLAEGRADLYPRLGPTSEWDTAAAQA
VLESAGGRVVVYGESNPLVYNKKEQLLNPWFMATAPGWNTH

Sequences:

>Translated_281_residues
MAVFAWPEHHGPQVAGGYMTLVALDKTTLDKLGQIARQAGAAIMAVYGQGDVAVTQKSDDSPVTAADLASHTVIIEQLAA
AFPFTPVLSEEAVIDWETRRQWQEYFLIDPLDGTKEFIKRNGEFTVNIALVRDGIAVAGVVFAPVLDTCYLGAEGLGAWL
ECQGKQQPLQGSAQKRDVPVVVGSRSHQSAEMAGYLADLGDHELLSVGSSLKFCMLAEGRADLYPRLGPTSEWDTAAAQA
VLESAGGRVVVYGESNPLVYNKKEQLLNPWFMATAPGWNTH
>Mature_280_residues
AVFAWPEHHGPQVAGGYMTLVALDKTTLDKLGQIARQAGAAIMAVYGQGDVAVTQKSDDSPVTAADLASHTVIIEQLAAA
FPFTPVLSEEAVIDWETRRQWQEYFLIDPLDGTKEFIKRNGEFTVNIALVRDGIAVAGVVFAPVLDTCYLGAEGLGAWLE
CQGKQQPLQGSAQKRDVPVVVGSRSHQSAEMAGYLADLGDHELLSVGSSLKFCMLAEGRADLYPRLGPTSEWDTAAAQAV
LESAGGRVVVYGESNPLVYNKKEQLLNPWFMATAPGWNTH

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI116812595, Length=277, Percent_Identity=27.4368231046931, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI7657236, Length=236, Percent_Identity=29.2372881355932, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI221625487, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031789, Length=226, Percent_Identity=27.4336283185841, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790659, Length=249, Percent_Identity=53.4136546184739, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1788882, Length=221, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=270, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=270, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193202572, Length=242, Percent_Identity=26.0330578512397, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=206, Percent_Identity=29.6116504854369, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664926, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 30275; Mature: 30143

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFAWPEHHGPQVAGGYMTLVALDKTTLDKLGQIARQAGAAIMAVYGQGDVAVTQKSDD
CEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCC
SPVTAADLASHTVIIEQLAAAFPFTPVLSEEAVIDWETRRQWQEYFLIDPLDGTKEFIKR
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHEEEECCCCCHHHHHHC
NGEFTVNIALVRDGIAVAGVVFAPVLDTCYLGAEGLGAWLECQGKQQPLQGSAQKRDVPV
CCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCE
VVGSRSHQSAEMAGYLADLGDHELLSVGSSLKFCMLAEGRADLYPRLGPTSEWDTAAAQA
EECCCCCCHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHH
VLESAGGRVVVYGESNPLVYNKKEQLLNPWFMATAPGWNTH
HHHHCCCEEEEEECCCCEEECCHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
AVFAWPEHHGPQVAGGYMTLVALDKTTLDKLGQIARQAGAAIMAVYGQGDVAVTQKSDD
EEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCC
SPVTAADLASHTVIIEQLAAAFPFTPVLSEEAVIDWETRRQWQEYFLIDPLDGTKEFIKR
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHEEEECCCCCHHHHHHC
NGEFTVNIALVRDGIAVAGVVFAPVLDTCYLGAEGLGAWLECQGKQQPLQGSAQKRDVPV
CCCEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCE
VVGSRSHQSAEMAGYLADLGDHELLSVGSSLKFCMLAEGRADLYPRLGPTSEWDTAAAQA
EECCCCCCHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHH
VLESAGGRVVVYGESNPLVYNKKEQLLNPWFMATAPGWNTH
HHHHCCCEEEEEECCCCEEECCHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]