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The map label for this gene is aroC

Identifier: 119775294

GI number: 119775294

Start: 2608704

End: 2609801

Strand: Reverse

Name: aroC

Synonym: Sama_2159

Alternate gene names: 119775294

Gene position: 2609801-2608704 (Counterclockwise)

Preceding gene: 119775295

Following gene: 119775293

Centisome position: 60.61

GC content: 57.38

Gene sequence:

>1098_bases
ATGTCGGGGAACAGCATAGGTCAGAATTTCGTGGTTACTACCTTTGGCGAGAGCCATGGGGTGGCGCTCGGTTGCATTAT
CGATGGTTGCCCTCCGGGCCTCGAGCTTACCGAAGCTGATATGCAGCACGATCTTGACCGTCGCCGTCCGGGCACGTCCC
GCTACACCACGGCGCGCCGCGAGCCGGACGAAGTGCGTATTCTCTCAGGTGTTTTCGAAGGCAAAACAACAGGAACCTCC
ATTGGTCTGATTATCGAAAACACCGATCAGCGCAGCCAGGACTACAGCAATATCAAAGACCTGTTCCGCCCCGGTCACGC
CGATTACACCTATCAACAAAAGTACGGTCTGCGGGATTATCGCGGCGGTGGCCGTTCGTCCGCCCGAGAAACCGCCATGC
GGGTTGCCGCCGGCGCTGTGGCGAAAAAGTACCTCAAGGCCGTTCACGGGATCGAAATTTACGGCTTCCTGTCGCAACTT
GGCCCCATTGAGGCAGAGCACATCGACCGCGAGCAGATTGAGCAAAACGCCTTTTTCTTCCCTGATGCCAGCAAGCTTGA
AGCGCTGGATGAATATATGCGCGAGCTGAAAAAATCCGGCGACTCCATCGGTGCCAAGGTCAGCGTGATTGCCACCAATG
TACCAGTGGGCCTGGGCGAGCCTGTGTTTGACCGTCTTGATGCCGACATCGCCCATGCGCTGATGGGCATCAATGCCGTG
AAGGGAGTGGAAATTGGCGATGGTTTCGCGGTAGTGACCCAAAAGGGCTCCGAGCATCGTGATTTGATGTCACCCGAGGG
CTTTGCCAGCAACCATGCCGGCGGCGTGCTTGGCGGCATTTCATCCGGTCAGCCAATTGTGGCCCATATGGCGCTTAAGC
CAACCTCCAGTATCAGCATTCCCGGCGAGAGCATGACAGTGCAGGGCAATACTGCGGAAGTGGTTACCAAGGGCCGTCAC
GACCCCTGCGTGGGCATTCGCGCCGTGCCTATTGCCGAGGCCATGTTGGCGATTGTATTGATGGATCATCTGCTCAGACA
CCGTGCTCAGAATCAGCACGTGCACAGCGAAACCCCTGTGCTGGGGATGCGCTCTTAA

Upstream 100 bases:

>100_bases
TTCGCCATCTATAAAGATAGGGAATAATGGGGCTGCCCCGGTAGCGCCGGGGCACGCCACTGAGGTTACACATTAAACAG
ACAAGAGGATACGCGCGCGG

Downstream 100 bases:

>100_bases
GGAAAACCGTGTTCAAGACGTCACCCATGAGCGCCGAGGTTCAGCTACGCTGGCTCGGCGCCTGTTATTTCTTCTTCTTT
GCCATTCTTGGCGTCATGGT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGKTTGTS
IGLIIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGLRDYRGGGRSSARETAMRVAAGAVAKKYLKAVHGIEIYGFLSQL
GPIEAEHIDREQIEQNAFFFPDASKLEALDEYMRELKKSGDSIGAKVSVIATNVPVGLGEPVFDRLDADIAHALMGINAV
KGVEIGDGFAVVTQKGSEHRDLMSPEGFASNHAGGVLGGISSGQPIVAHMALKPTSSISIPGESMTVQGNTAEVVTKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQHVHSETPVLGMRS

Sequences:

>Translated_365_residues
MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGKTTGTS
IGLIIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGLRDYRGGGRSSARETAMRVAAGAVAKKYLKAVHGIEIYGFLSQL
GPIEAEHIDREQIEQNAFFFPDASKLEALDEYMRELKKSGDSIGAKVSVIATNVPVGLGEPVFDRLDADIAHALMGINAV
KGVEIGDGFAVVTQKGSEHRDLMSPEGFASNHAGGVLGGISSGQPIVAHMALKPTSSISIPGESMTVQGNTAEVVTKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQHVHSETPVLGMRS
>Mature_364_residues
SGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGKTTGTSI
GLIIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGLRDYRGGGRSSARETAMRVAAGAVAKKYLKAVHGIEIYGFLSQLG
PIEAEHIDREQIEQNAFFFPDASKLEALDEYMRELKKSGDSIGAKVSVIATNVPVGLGEPVFDRLDADIAHALMGINAVK
GVEIGDGFAVVTQKGSEHRDLMSPEGFASNHAGGVLGGISSGQPIVAHMALKPTSSISIPGESMTVQGNTAEVVTKGRHD
PCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQHVHSETPVLGMRS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=76.0445682451253, Blast_Score=547, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=44.5652173913043, Blast_Score=300, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SHEAM (A1S7K8)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928034.1
- ProteinModelPortal:   A1S7K8
- SMR:   A1S7K8
- STRING:   A1S7K8
- GeneID:   4604409
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2159
- NMPDR:   fig|326297.7.peg.2027
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   A1S7K8
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39303; Mature: 39172

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARR
CCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDEVRILSGVFEGKTTGTSIGLIIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGLRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKAVHGIEIYGFLSQLGPIEAEHIDREQIEQNAFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHCCHHHHHCCCEEC
PDASKLEALDEYMRELKKSGDSIGAKVSVIATNVPVGLGEPVFDRLDADIAHALMGINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVVTQKGSEHRDLMSPEGFASNHAGGVLGGISSGQPIVAHMALKPTSSISI
CCEEECCCEEEEECCCCCHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCEEC
PGESMTVQGNTAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQHVHSETPV
CCCCEEECCCCHHEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LGMRS
CCCCC
>Mature Secondary Structure 
SGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARR
CCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDEVRILSGVFEGKTTGTSIGLIIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGLRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKAVHGIEIYGFLSQLGPIEAEHIDREQIEQNAFFF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHCCHHHHHCCCEEC
PDASKLEALDEYMRELKKSGDSIGAKVSVIATNVPVGLGEPVFDRLDADIAHALMGINAV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVVTQKGSEHRDLMSPEGFASNHAGGVLGGISSGQPIVAHMALKPTSSISI
CCEEECCCEEEEECCCCCHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCEEC
PGESMTVQGNTAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQHVHSETPV
CCCCEEECCCCHHEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LGMRS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA