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The map label for this gene is hcaT [H]

Identifier: 119775293

GI number: 119775293

Start: 2607526

End: 2608695

Strand: Reverse

Name: hcaT [H]

Synonym: Sama_2158

Alternate gene names: 119775293

Gene position: 2608695-2607526 (Counterclockwise)

Preceding gene: 119775294

Following gene: 119775292

Centisome position: 60.58

GC content: 55.56

Gene sequence:

>1170_bases
GTGTTCAAGACGTCACCCATGAGCGCCGAGGTTCAGCTACGCTGGCTCGGCGCCTGTTATTTCTTCTTCTTTGCCATTCT
TGGCGTCATGGTGCCTTACCTTGGCGTCTTCTTCGAATCCCGCGGCTTTAACGCCACTGAAATCGGCTCTCTGCTTGCCA
TCTTAATGGCCACCCGCATCATTGCGCCTAATCTGTGGGCCATAGTTGCCGACAAAACCGGGATGCGCAGTGAGCTGATT
AAAATCGGTGCTGGTGCCGGTGCACTTACCTATTTGAGCTTTTTCCATCCGGGCGCCTTCTGGTACATGGTGGTCAGCCT
CACTGTGTATACCTTTTTCTGGAATGCGATTTTGGCGCAGCTTGAGGTGATAACCCTTGAGACCCTCGGTGATAAGCCGC
AGCGCTACGGCATCATCAGAAGCTTTGGCAGTCTGGGTTACATTGTACTGGTGGTGGCCGCCGGCTTTGCCATCGGTCAC
TGGGGCCCGGAAGTGTTGCCCTACATCGGCATGGGCCTCTTTGCCGGAATGCTGGCGGCCTGTTTGCCGCTGCCTGCCAA
TAGGGTGAAGCTAAGCCGGGATACGCCCAAGGTGAAAGTCAAACTGGCCGGTCCCATCGGTTGGTTTCTATTGTCGGCCA
TCTTGCTGCAAATGAGCGCCGGACCTTTTTACGGCTTTTTCGTGCTGTATCTGAAACACGCCGGTTACAGCGAGGCGACA
GCCGGTCTCTTTGTGGCCCTCGGAGTCATTGCCGAAATCGTCATGTTTATGCTCGCGCCGAGGCTACTTGGCAAATACGG
CATCAAGCCGCTGCTGTTTATCAGCATTTTATTTACCGCATTTCGCTGGTTGATGATGGCCTGGGGCGTTGAGAGTCTCT
TCTGGTTGTCGCTGAGTCAGCTGTTGCATGCCTTTACCTTCGGCTTAGTGCATGCCGCCTCTATTCAGTTTATTCACCAA
CAGTTTGATGTGAGCCGCCGCAGCACAGGGCAGGCGCTCTATGCCAGTCTCAGTTTTGGTGTTGGTGGTGCGCTGGGGAC
CTGGGCCTGCGGCCTGGTCTACAGCCATAACCCCAGCCTGAGTTGGGTGCTGGCGGCTGGATTTGCCTTTGTGGCGGCGC
TGCTTGTGTTGCCTTTGCCGGGACGTAGAGTCGAAACGGCAGCCGTTTAA

Upstream 100 bases:

>100_bases
TGGCGATTGTATTGATGGATCATCTGCTCAGACACCGTGCTCAGAATCAGCACGTGCACAGCGAAACCCCTGTGCTGGGG
ATGCGCTCTTAAGGAAAACC

Downstream 100 bases:

>100_bases
AGACAAGTTAGAACAGAATAAGAAGTACCCTAATAAAGAGGAAGTCCATGGCCAATAAGTTCAGATTGGGCCTGATTATT
AACCCGCTGGCTGGTCTTGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MFKTSPMSAEVQLRWLGACYFFFFAILGVMVPYLGVFFESRGFNATEIGSLLAILMATRIIAPNLWAIVADKTGMRSELI
KIGAGAGALTYLSFFHPGAFWYMVVSLTVYTFFWNAILAQLEVITLETLGDKPQRYGIIRSFGSLGYIVLVVAAGFAIGH
WGPEVLPYIGMGLFAGMLAACLPLPANRVKLSRDTPKVKVKLAGPIGWFLLSAILLQMSAGPFYGFFVLYLKHAGYSEAT
AGLFVALGVIAEIVMFMLAPRLLGKYGIKPLLFISILFTAFRWLMMAWGVESLFWLSLSQLLHAFTFGLVHAASIQFIHQ
QFDVSRRSTGQALYASLSFGVGGALGTWACGLVYSHNPSLSWVLAAGFAFVAALLVLPLPGRRVETAAV

Sequences:

>Translated_389_residues
MFKTSPMSAEVQLRWLGACYFFFFAILGVMVPYLGVFFESRGFNATEIGSLLAILMATRIIAPNLWAIVADKTGMRSELI
KIGAGAGALTYLSFFHPGAFWYMVVSLTVYTFFWNAILAQLEVITLETLGDKPQRYGIIRSFGSLGYIVLVVAAGFAIGH
WGPEVLPYIGMGLFAGMLAACLPLPANRVKLSRDTPKVKVKLAGPIGWFLLSAILLQMSAGPFYGFFVLYLKHAGYSEAT
AGLFVALGVIAEIVMFMLAPRLLGKYGIKPLLFISILFTAFRWLMMAWGVESLFWLSLSQLLHAFTFGLVHAASIQFIHQ
QFDVSRRSTGQALYASLSFGVGGALGTWACGLVYSHNPSLSWVLAAGFAFVAALLVLPLPGRRVETAAV
>Mature_389_residues
MFKTSPMSAEVQLRWLGACYFFFFAILGVMVPYLGVFFESRGFNATEIGSLLAILMATRIIAPNLWAIVADKTGMRSELI
KIGAGAGALTYLSFFHPGAFWYMVVSLTVYTFFWNAILAQLEVITLETLGDKPQRYGIIRSFGSLGYIVLVVAAGFAIGH
WGPEVLPYIGMGLFAGMLAACLPLPANRVKLSRDTPKVKVKLAGPIGWFLLSAILLQMSAGPFYGFFVLYLKHAGYSEAT
AGLFVALGVIAEIVMFMLAPRLLGKYGIKPLLFISILFTAFRWLMMAWGVESLFWLSLSQLLHAFTFGLVHAASIQFIHQ
QFDVSRRSTGQALYASLSFGVGGALGTWACGLVYSHNPSLSWVLAAGFAFVAALLVLPLPGRRVETAAV

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=384, Percent_Identity=26.8229166666667, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 42422; Mature: 42422

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKTSPMSAEVQLRWLGACYFFFFAILGVMVPYLGVFFESRGFNATEIGSLLAILMATRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IAPNLWAIVADKTGMRSELIKIGAGAGALTYLSFFHPGAFWYMVVSLTVYTFFWNAILAQ
HCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LEVITLETLGDKPQRYGIIRSFGSLGYIVLVVAAGFAIGHWGPEVLPYIGMGLFAGMLAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
CLPLPANRVKLSRDTPKVKVKLAGPIGWFLLSAILLQMSAGPFYGFFVLYLKHAGYSEAT
HCCCCCCCEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
AGLFVALGVIAEIVMFMLAPRLLGKYGIKPLLFISILFTAFRWLMMAWGVESLFWLSLSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHAFTFGLVHAASIQFIHQQFDVSRRSTGQALYASLSFGVGGALGTWACGLVYSHNPSL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCHHHHHHHHHEEECCCCH
SWVLAAGFAFVAALLVLPLPGRRVETAAV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFKTSPMSAEVQLRWLGACYFFFFAILGVMVPYLGVFFESRGFNATEIGSLLAILMATRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IAPNLWAIVADKTGMRSELIKIGAGAGALTYLSFFHPGAFWYMVVSLTVYTFFWNAILAQ
HCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LEVITLETLGDKPQRYGIIRSFGSLGYIVLVVAAGFAIGHWGPEVLPYIGMGLFAGMLAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
CLPLPANRVKLSRDTPKVKVKLAGPIGWFLLSAILLQMSAGPFYGFFVLYLKHAGYSEAT
HCCCCCCCEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
AGLFVALGVIAEIVMFMLAPRLLGKYGIKPLLFISILFTAFRWLMMAWGVESLFWLSLSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLHAFTFGLVHAASIQFIHQQFDVSRRSTGQALYASLSFGVGGALGTWACGLVYSHNPSL
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCHHHHHHHHHEEECCCCH
SWVLAAGFAFVAALLVLPLPGRRVETAAV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]