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The map label for this gene is trpD

Identifier: 119775266

GI number: 119775266

Start: 2576274

End: 2577308

Strand: Direct

Name: trpD

Synonym: Sama_2131

Alternate gene names: 119775266

Gene position: 2576274-2577308 (Clockwise)

Preceding gene: 119775265

Following gene: 119775267

Centisome position: 59.83

GC content: 57.58

Gene sequence:

>1035_bases
ATGAGCAAGGATGTAAGACAACTCCTGGATAAAACCTACGGCGGTAACCCATTATCCCGCGAAGAAGCCAAATGCCTTTT
TGCCTCGCTGGTGAGGGGCGAGCTCGATGAGGTCACCATAGCGGCGCTTTTGATGGCCCTCAAGGTGCGGGGCGAAACCA
TCGACGAAATCAGCGGCGCGGCCGATGCCATGCGCGAAGCGGCCAATTCCTTCCCCCGGCCCGCACTTGATGGTGGTATT
TTGGATATCGTCGGCACCGGCGGTGACGGCTTCAACACCATCAACATTTCCACCACAGCGACCTTTGTGGCGGCGGCTGC
AGGCGCCAATGTGGCCAAACATGGGAATCGCAGCGTATCGTCCAAATCCGGATCGTCGGATCTCCTCGGCCAGTTCGGCA
TCGAGTTAACCATGGCGCCACAAACGGCGGCCAATTGCCTTGAAGCCCTGGGTATTTGTTTTCTGTTTGCTCCCCATTAC
CACGGTGGAGTAAAACATGCGGTGCCGGTACGGCAAAAGCTCGCTACCCGCACCCTGTTCAATGTACTCGGGCCCCTGAT
TAATCCCAGTCACCCCGACTTTATGCTGCTTGGGGTGTACAGTGAGACGCTGGTCCGCCCCATCGCCGAGGTGCTCTGCG
CCCTTGGGGTAAAACGCGCCATGGTGGTACATGGCGAAGGGCTGGATGAAGTGGCGCTCCACGGCACAACTCAGGTGTGC
GAACTCAGAAACGGTGAGCTTGTGGATTACTCGCTGTCACCAAAAGACTTTGGGCTTGAACCTGTCCAGGTAACTGAACT
TGAAGGCGGTAGTCCCGAAGACAATGCGCTCATCACCGCGGCCATTTTAAAAGGCGAAGGCAAGGCAGCCCACCGGGATG
CTGTGGCACTCAATGCAGGCTGTGCGCTCTATGTGGCAGGGCTTGCCGACACGCCCCAGGCAGGATTCAAGCTTGCCATT
GACACCCTCGCCTCCGGCAAGGCATATGAAAAACTGATTGGCCTCGCCGCCATGAGTCAGCAGGACAAGGCGTAA

Upstream 100 bases:

>100_bases
TCCAGTTTCACCCTGAGTCGATTCTGACAACCCTTGGCAGTACCTTGCTGGTGCAAAGCCTGCAATACCTCACCGGCTTG
GCTGCCAAAGGAGAGCTGCA

Downstream 100 bases:

>100_bases
GGAATTAAGCCCCATGAGCAATGTGTTAACCAAGATTATCGACACCAAATACGCCCATATCGATGCCCTCAAGCAGCGAT
TCCCGGAAGCCAGCCTGACG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSKDVRQLLDKTYGGNPLSREEAKCLFASLVRGELDEVTIAALLMALKVRGETIDEISGAADAMREAANSFPRPALDGGI
LDIVGTGGDGFNTINISTTATFVAAAAGANVAKHGNRSVSSKSGSSDLLGQFGIELTMAPQTAANCLEALGICFLFAPHY
HGGVKHAVPVRQKLATRTLFNVLGPLINPSHPDFMLLGVYSETLVRPIAEVLCALGVKRAMVVHGEGLDEVALHGTTQVC
ELRNGELVDYSLSPKDFGLEPVQVTELEGGSPEDNALITAAILKGEGKAAHRDAVALNAGCALYVAGLADTPQAGFKLAI
DTLASGKAYEKLIGLAAMSQQDKA

Sequences:

>Translated_344_residues
MSKDVRQLLDKTYGGNPLSREEAKCLFASLVRGELDEVTIAALLMALKVRGETIDEISGAADAMREAANSFPRPALDGGI
LDIVGTGGDGFNTINISTTATFVAAAAGANVAKHGNRSVSSKSGSSDLLGQFGIELTMAPQTAANCLEALGICFLFAPHY
HGGVKHAVPVRQKLATRTLFNVLGPLINPSHPDFMLLGVYSETLVRPIAEVLCALGVKRAMVVHGEGLDEVALHGTTQVC
ELRNGELVDYSLSPKDFGLEPVQVTELEGGSPEDNALITAAILKGEGKAAHRDAVALNAGCALYVAGLADTPQAGFKLAI
DTLASGKAYEKLIGLAAMSQQDKA
>Mature_343_residues
SKDVRQLLDKTYGGNPLSREEAKCLFASLVRGELDEVTIAALLMALKVRGETIDEISGAADAMREAANSFPRPALDGGIL
DIVGTGGDGFNTINISTTATFVAAAAGANVAKHGNRSVSSKSGSSDLLGQFGIELTMAPQTAANCLEALGICFLFAPHYH
GGVKHAVPVRQKLATRTLFNVLGPLINPSHPDFMLLGVYSETLVRPIAEVLCALGVKRAMVVHGEGLDEVALHGTTQVCE
LRNGELVDYSLSPKDFGLEPVQVTELEGGSPEDNALITAAILKGEGKAAHRDAVALNAGCALYVAGLADTPQAGFKLAID
TLASGKAYEKLIGLAAMSQQDKA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=336, Percent_Identity=53.5714285714286, Blast_Score=311, Evalue=5e-86,
Organism=Saccharomyces cerevisiae, GI6320561, Length=259, Percent_Identity=35.1351351351351, Blast_Score=122, Evalue=6e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_SHEAM (A1S7I0)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928006.1
- ProteinModelPortal:   A1S7I0
- SMR:   A1S7I0
- STRING:   A1S7I0
- GeneID:   4604381
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2131
- NMPDR:   fig|326297.7.peg.2001
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   YLYQDTD
- PhylomeDB:   A1S7I0
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35895; Mature: 35764

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDVRQLLDKTYGGNPLSREEAKCLFASLVRGELDEVTIAALLMALKVRGETIDEISGA
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ADAMREAANSFPRPALDGGILDIVGTGGDGFNTINISTTATFVAAAAGANVAKHGNRSVS
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHCCHHHHCCCCCCC
SKSGSSDLLGQFGIELTMAPQTAANCLEALGICFLFAPHYHGGVKHAVPVRQKLATRTLF
CCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NVLGPLINPSHPDFMLLGVYSETLVRPIAEVLCALGVKRAMVVHGEGLDEVALHGTTQVC
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHCCCHHHH
ELRNGELVDYSLSPKDFGLEPVQVTELEGGSPEDNALITAAILKGEGKAAHRDAVALNAG
CCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCEEECCC
CALYVAGLADTPQAGFKLAIDTLASGKAYEKLIGLAAMSQQDKA
CEEEEECCCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKDVRQLLDKTYGGNPLSREEAKCLFASLVRGELDEVTIAALLMALKVRGETIDEISGA
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ADAMREAANSFPRPALDGGILDIVGTGGDGFNTINISTTATFVAAAAGANVAKHGNRSVS
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHCCHHHHCCCCCCC
SKSGSSDLLGQFGIELTMAPQTAANCLEALGICFLFAPHYHGGVKHAVPVRQKLATRTLF
CCCCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NVLGPLINPSHPDFMLLGVYSETLVRPIAEVLCALGVKRAMVVHGEGLDEVALHGTTQVC
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHCCCHHHH
ELRNGELVDYSLSPKDFGLEPVQVTELEGGSPEDNALITAAILKGEGKAAHRDAVALNAG
CCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCEEECCC
CALYVAGLADTPQAGFKLAIDTLASGKAYEKLIGLAAMSQQDKA
CEEEEECCCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA