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The map label for this gene is sohB [H]

Identifier: 119775254

GI number: 119775254

Start: 2563080

End: 2564093

Strand: Reverse

Name: sohB [H]

Synonym: Sama_2119

Alternate gene names: 119775254

Gene position: 2564093-2563080 (Counterclockwise)

Preceding gene: 119775255

Following gene: 119775253

Centisome position: 59.55

GC content: 53.55

Gene sequence:

>1014_bases
TTGGAATTTTTATACGAATATGGGCTGTTTCTTGCCAAGGCTGTGACAGTGGTCGCCGCCATCGGTGCCATTCTGGTGAT
GGTGTTTGCCGGTGCGGCCCGAGGTAAGGGTGATAAAGGCGAACTGGTGCTGACCAATGTCACCGAAGAACTCGATCATT
TAAAGATGCACCTTAAACACGAACTGCTTGATAAGAAAGCATTCAAGGCGTACGAAAAGGCCCAAAAAGCCGAGGCCAAA
GAGGCTGAGAAGCAGGATAAGCCTAAGCCCAGAACGTTTGTGCTGGATTTTAAAGGCAGTATCGATGCCCATGAAGTAGC
CTCTTTACGGGAAGAAATCAGCGCGATACTGACCATTGCCGAAAAAGGCGATGAGGTGCTGCTTAACGTCGAGAGCGGTG
GTGGCATGGTACATGGTTACGGTCTTGCGGCGAGCCAGCTCGACAGACTGCGTCAGGCCGACATTCCTCTGACCGCCTGT
ATCGACAAGGTGGCGGCCAGTGGCGGCTACATGATGGCCTGCGTGGCCAATCGCATCTACGCCGCGCCCTTTGCCATTGT
GGGGTCTATCGGTGTGGTGGCTCAACTGCCGAACTTCAACCGCTTGCTGAAAAAGCATGATATTGATTACGAGCAGCACA
CCGCCGGGGACTTTAAGCGCACTCTGACGTTGTTTGGTGAAAATACCGAAGAGGGCAGACAGAAATTCCGTGAAGAGCTG
GAGGAGACCCATCAGCTGTTTAAGGCCTTCGTATCCAAGTATCGCCCTGAGCTTGATCTGGACAAGGTTGCCACCGGTGA
GCACTGGTACGGACAGCAGGCCCTGGATTTGGGGCTGGTGGACAGCATCAGCACCAGCGACGACCTGATGCTGACAGCGG
CCAAAGACAGAACCCTGATTAAACTGCGTTATCAGCCGCGGAAGAAGCTCGCCGACAAGCTGGCCCACAGCGCCGCACTG
ACAGTCAGTACTTTTTTTGGAAAGCTGGCGGAAAAGAATAAACCGCTGCCATAA

Upstream 100 bases:

>100_bases
CCGGTTTTTTATTGGTTTTAGCGGCTGAATTGTTAGAATAGCCGCACTTTTATGCTCGCCAGGCCAGGTTGCCGGGTGTT
GGGATGCTTTGGAGCGGAAT

Downstream 100 bases:

>100_bases
ATTTCCTTGCATGTTGTATATATTAAAAGCCTGCTTTTGCAGGCTTTTTTGTGCGCCCATTTAGGCTGAACACCCTAATG
TCACTCTCTGTAGCCGGGGT

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MEFLYEYGLFLAKAVTVVAAIGAILVMVFAGAARGKGDKGELVLTNVTEELDHLKMHLKHELLDKKAFKAYEKAQKAEAK
EAEKQDKPKPRTFVLDFKGSIDAHEVASLREEISAILTIAEKGDEVLLNVESGGGMVHGYGLAASQLDRLRQADIPLTAC
IDKVAASGGYMMACVANRIYAAPFAIVGSIGVVAQLPNFNRLLKKHDIDYEQHTAGDFKRTLTLFGENTEEGRQKFREEL
EETHQLFKAFVSKYRPELDLDKVATGEHWYGQQALDLGLVDSISTSDDLMLTAAKDRTLIKLRYQPRKKLADKLAHSAAL
TVSTFFGKLAEKNKPLP

Sequences:

>Translated_337_residues
MEFLYEYGLFLAKAVTVVAAIGAILVMVFAGAARGKGDKGELVLTNVTEELDHLKMHLKHELLDKKAFKAYEKAQKAEAK
EAEKQDKPKPRTFVLDFKGSIDAHEVASLREEISAILTIAEKGDEVLLNVESGGGMVHGYGLAASQLDRLRQADIPLTAC
IDKVAASGGYMMACVANRIYAAPFAIVGSIGVVAQLPNFNRLLKKHDIDYEQHTAGDFKRTLTLFGENTEEGRQKFREEL
EETHQLFKAFVSKYRPELDLDKVATGEHWYGQQALDLGLVDSISTSDDLMLTAAKDRTLIKLRYQPRKKLADKLAHSAAL
TVSTFFGKLAEKNKPLP
>Mature_337_residues
MEFLYEYGLFLAKAVTVVAAIGAILVMVFAGAARGKGDKGELVLTNVTEELDHLKMHLKHELLDKKAFKAYEKAQKAEAK
EAEKQDKPKPRTFVLDFKGSIDAHEVASLREEISAILTIAEKGDEVLLNVESGGGMVHGYGLAASQLDRLRQADIPLTAC
IDKVAASGGYMMACVANRIYAAPFAIVGSIGVVAQLPNFNRLLKKHDIDYEQHTAGDFKRTLTLFGENTEEGRQKFREEL
EETHQLFKAFVSKYRPELDLDKVATGEHWYGQQALDLGLVDSISTSDDLMLTAAKDRTLIKLRYQPRKKLADKLAHSAAL
TVSTFFGKLAEKNKPLP

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=348, Percent_Identity=57.183908045977, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1788064, Length=180, Percent_Identity=31.1111111111111, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 37253; Mature: 37253

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLYEYGLFLAKAVTVVAAIGAILVMVFAGAARGKGDKGELVLTNVTEELDHLKMHLKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
ELLDKKAFKAYEKAQKAEAKEAEKQDKPKPRTFVLDFKGSIDAHEVASLREEISAILTIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
EKGDEVLLNVESGGGMVHGYGLAASQLDRLRQADIPLTACIDKVAASGGYMMACVANRIY
CCCCEEEEEEECCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHH
AAPFAIVGSIGVVAQLPNFNRLLKKHDIDYEQHTAGDFKRTLTLFGENTEEGRQKFREEL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHH
EETHQLFKAFVSKYRPELDLDKVATGEHWYGQQALDLGLVDSISTSDDLMLTAAKDRTLI
HHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCEEE
KLRYQPRKKLADKLAHSAALTVSTFFGKLAEKNKPLP
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEFLYEYGLFLAKAVTVVAAIGAILVMVFAGAARGKGDKGELVLTNVTEELDHLKMHLKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
ELLDKKAFKAYEKAQKAEAKEAEKQDKPKPRTFVLDFKGSIDAHEVASLREEISAILTIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
EKGDEVLLNVESGGGMVHGYGLAASQLDRLRQADIPLTACIDKVAASGGYMMACVANRIY
CCCCEEEEEEECCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHH
AAPFAIVGSIGVVAQLPNFNRLLKKHDIDYEQHTAGDFKRTLTLFGENTEEGRQKFREEL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHH
EETHQLFKAFVSKYRPELDLDKVATGEHWYGQQALDLGLVDSISTSDDLMLTAAKDRTLI
HHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCEEE
KLRYQPRKKLADKLAHSAALTVSTFFGKLAEKNKPLP
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]