Click here to switch to the map view.

The map label for this gene is aat

Identifier: 119775188

GI number: 119775188

Start: 2488981

End: 2489691

Strand: Direct

Name: aat

Synonym: Sama_2053

Alternate gene names: 119775188

Gene position: 2488981-2489691 (Clockwise)

Preceding gene: 119775186

Following gene: 119775189

Centisome position: 57.8

GC content: 53.87

Gene sequence:

>711_bases
GTGAACGGCCTGTCTTTTATCGATGATGAACAGATAAGATTTCCTTCTCCCGAGCTCGCCTTGTCTGAGCCCAATGGGCT
GCTGGCCATTGGCGGCTCCCTGCATCCCAAACGTTTGCTGGCGGCCTACTATGATGGCATTTTCCCTTGGTTCAATGCCG
AGGACCCTATTCTGTGGTGGTCGCCTGACCCCCGGGCTGTCTTTCTTCCCGGTGAGCTTAAAATCAGTCGCAGTCTTAAG
AAAAGCCTTAAAAAGCATCCATGGCGCGTCACGATCAATCATGCCTTTGCCGATGTGATGGCCGGCTGTGCTCAGCCCCG
TAAAAAACAACGCGATACCTGGATAACCCAGGAAATTCAACTGGCCTACCTTGAGATGCACAGCCAAGGGCATGCTCACT
CGGTAGAAGTGTGGATGAAAGACCGCCTGGTTGGTGGTCTTTACGGGCTTGCCATAGGAAAAGTCTTTTGTGGTGAGTCC
ATGTTCCATCGTGAAACCGATGCATCCAAGCTGGCGATGATGGCGCTGCACCAGCATTTACTGCAGCACGACTTTAAGCT
GCTGGATGCGCAGATCATGAATCCGCACCTCGAAAGCCTTGGCGCCCGCGAAGTCAGCCGGACAGCATTCCTCTCGCTGC
TTAAACGTTACCGGGACGAACCCGTCGCCAAAAGCTGCTGGCTGCCCAGGGAGATGCCAATTGGAAAGTAG

Upstream 100 bases:

>100_bases
AGAAACATGCTGTCAAAAGCACCAGACAATAGAGTGCAGGTTTCCACATAATCCAATTTCCGCTACTTTATTAGGATGAA
CCCTTTGATAGTACGCCTTT

Downstream 100 bases:

>100_bases
TACCCACGTCAGCGTTGGGATAAGCCAGCTATTCCAATGCAGTTACCTTGAAGATCAACAGGAACAGCTACTCATTATTC
AGGAGCCTTTTCTCGATCCC

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MNGLSFIDDEQIRFPSPELALSEPNGLLAIGGSLHPKRLLAAYYDGIFPWFNAEDPILWWSPDPRAVFLPGELKISRSLK
KSLKKHPWRVTINHAFADVMAGCAQPRKKQRDTWITQEIQLAYLEMHSQGHAHSVEVWMKDRLVGGLYGLAIGKVFCGES
MFHRETDASKLAMMALHQHLLQHDFKLLDAQIMNPHLESLGAREVSRTAFLSLLKRYRDEPVAKSCWLPREMPIGK

Sequences:

>Translated_236_residues
MNGLSFIDDEQIRFPSPELALSEPNGLLAIGGSLHPKRLLAAYYDGIFPWFNAEDPILWWSPDPRAVFLPGELKISRSLK
KSLKKHPWRVTINHAFADVMAGCAQPRKKQRDTWITQEIQLAYLEMHSQGHAHSVEVWMKDRLVGGLYGLAIGKVFCGES
MFHRETDASKLAMMALHQHLLQHDFKLLDAQIMNPHLESLGAREVSRTAFLSLLKRYRDEPVAKSCWLPREMPIGK
>Mature_236_residues
MNGLSFIDDEQIRFPSPELALSEPNGLLAIGGSLHPKRLLAAYYDGIFPWFNAEDPILWWSPDPRAVFLPGELKISRSLK
KSLKKHPWRVTINHAFADVMAGCAQPRKKQRDTWITQEIQLAYLEMHSQGHAHSVEVWMKDRLVGGLYGLAIGKVFCGES
MFHRETDASKLAMMALHQHLLQHDFKLLDAQIMNPHLESLGAREVSRTAFLSLLKRYRDEPVAKSCWLPREMPIGK

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=224, Percent_Identity=52.6785714285714, Blast_Score=243, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_SHEAM (A1S7A2)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927928.1
- ProteinModelPortal:   A1S7A2
- SMR:   A1S7A2
- STRING:   A1S7A2
- GeneID:   4604303
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2053
- NMPDR:   fig|326297.7.peg.1928
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- PhylomeDB:   A1S7A2
- ProtClustDB:   PRK00301
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 26908; Mature: 26908

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLSFIDDEQIRFPSPELALSEPNGLLAIGGSLHPKRLLAAYYDGIFPWFNAEDPILWW
CCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEE
SPDPRAVFLPGELKISRSLKKSLKKHPWRVTINHAFADVMAGCAQPRKKQRDTWITQEIQ
CCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LAYLEMHSQGHAHSVEVWMKDRLVGGLYGLAIGKVFCGESMFHRETDASKLAMMALHQHL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHH
LQHDFKLLDAQIMNPHLESLGAREVSRTAFLSLLKRYRDEPVAKSCWLPREMPIGK
HHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MNGLSFIDDEQIRFPSPELALSEPNGLLAIGGSLHPKRLLAAYYDGIFPWFNAEDPILWW
CCCCCCCCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCEEEE
SPDPRAVFLPGELKISRSLKKSLKKHPWRVTINHAFADVMAGCAQPRKKQRDTWITQEIQ
CCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LAYLEMHSQGHAHSVEVWMKDRLVGGLYGLAIGKVFCGESMFHRETDASKLAMMALHQHL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHH
LQHDFKLLDAQIMNPHLESLGAREVSRTAFLSLLKRYRDEPVAKSCWLPREMPIGK
HHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA