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The map label for this gene is sbcB [H]

Identifier: 119775108

GI number: 119775108

Start: 2401157

End: 2402569

Strand: Direct

Name: sbcB [H]

Synonym: Sama_1973

Alternate gene names: 119775108

Gene position: 2401157-2402569 (Clockwise)

Preceding gene: 119775104

Following gene: 119775109

Centisome position: 55.76

GC content: 51.73

Gene sequence:

>1413_bases
ATGGAAAACTATATTCAGCCCACTATTTTTTGGCACGACTATGAAACGTTCGGGGCCAGTCCTGCGAAGGACAGGCCTGC
ACAATTTGCCGGTGTCAGAACCGATCTGGACCTGAATATCATCGACGAGCCTGTCACATTTTACTGCCGTTTAAGCCCCG
ATTATTTACCCGCACCGGAGGCGATTCTCATCACAGGTATTACGCCGCAACTGGCGAATCGTCAGGGCTTGCCTGAAACC
GAATTCATGGGCCGTATCCAGGCCATTTTCAGCAGACCCAATACCTGTGTTGCGGGCTACAACTCGCTGCGCTTTGATGA
TGAAGTAAGTCGCTACGGTTTTTACCGCAACTTTATTGACCCTTATGCCCGTGAGTGGCAACAGGGCAATTCCCGCTGGG
ATATTATCGATCTTGTGCGTGCCTGCTATGCCCTACGCCCGGAAGGCATTAACTGGCCAGAAAAAGAGGACGGCAGTCCC
AGCTTTAAACTTGAGCATCTGACAGCAGCCAATGGCCTTGGACACGACAAGGCCCACGATGCCATGTCAGATGTGTATGC
CACAATCGCACTGGCCCGGCTAATCAAGGAAAAGCAGCCCAAGCTGTTCGACTATTACTTCCGCTTAAGGCGTAAACAAG
CCGTGGCCGAACAAATCGATGTACTGGCGATGCAGCCGCTGGTGCACATCAGCTCCAAAATACCGGCAACCCAGGGCTGT
GCAACCTTGATAGCTCCGGTAGCGCACCATATGCGCAATAAAAATGCCGTCATTTGCGTCAATCTGGCCATGGACATTCA
GCCACTGATTGACCTCGATGTGGATGCACTGAGAACCCGGCTTTATACCAAGCGTGAAGACCTCGCCAATGATGAGCTGC
CCGTGCCTGTGAAGCAAATTCATCTGAATAAATGCCCCTTTGTCGCCAACGCCAAAACTCTGGATGACGCCAATGCTGAG
CGATTGGGCATAGATAAAGCCTTTGCCCGTGAACAATATCGCTTACTCAAACAGCATCCTGAGATCCGCGAAAAACTTAC
GGCACTGTTTGAGGAAGAACCCCAGGGTATGTCCAACGATCCCGACTACTCCCTCTACAGTGGTGGTTTTTTCTCTCCTG
CCGATCGTGCAAAAATGGACATCATACGGAATACGTCGCCGGAGCACTTAGCCGCGCTGGAACTGCAGTTTGATGATACC
CGTCTGCCAGAGATGCTCTTTCGCTACCGGGCTCGCAACTACCCGCTCACCTTGTCCTATGATGAAAGCCTGCGCTGGCG
AGAGTTTTGTCAGGCCCGCTTGAACGACCCTGACTATGTCATCCGCCTTGAAAACTTGCTGGAAGAAACCACCAAGGATG
AAAAAAAGCAAAAGCTCCTCGGCGCTTTATGTCAGTACCTGCAGTCGCTTTAG

Upstream 100 bases:

>100_bases
TTTACCCAACAAGACGGCAAGGAAACCGGTAAGAGATGAATATGGCGCATCAAGTGATAAGATAAGCGCTTAACTTGTCA
CGGACAGAGCTAATTTCCCG

Downstream 100 bases:

>100_bases
CAGAAAACCCACATAAAATGGGATTAGACTCCCATTATCTGTGTAACAGAATAACTAAACTGCAAGTCAGTAAAATTAAC
AGCGAAGGAAAACGGCTATG

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MENYIQPTIFWHDYETFGASPAKDRPAQFAGVRTDLDLNIIDEPVTFYCRLSPDYLPAPEAILITGITPQLANRQGLPET
EFMGRIQAIFSRPNTCVAGYNSLRFDDEVSRYGFYRNFIDPYAREWQQGNSRWDIIDLVRACYALRPEGINWPEKEDGSP
SFKLEHLTAANGLGHDKAHDAMSDVYATIALARLIKEKQPKLFDYYFRLRRKQAVAEQIDVLAMQPLVHISSKIPATQGC
ATLIAPVAHHMRNKNAVICVNLAMDIQPLIDLDVDALRTRLYTKREDLANDELPVPVKQIHLNKCPFVANAKTLDDANAE
RLGIDKAFAREQYRLLKQHPEIREKLTALFEEEPQGMSNDPDYSLYSGGFFSPADRAKMDIIRNTSPEHLAALELQFDDT
RLPEMLFRYRARNYPLTLSYDESLRWREFCQARLNDPDYVIRLENLLEETTKDEKKQKLLGALCQYLQSL

Sequences:

>Translated_470_residues
MENYIQPTIFWHDYETFGASPAKDRPAQFAGVRTDLDLNIIDEPVTFYCRLSPDYLPAPEAILITGITPQLANRQGLPET
EFMGRIQAIFSRPNTCVAGYNSLRFDDEVSRYGFYRNFIDPYAREWQQGNSRWDIIDLVRACYALRPEGINWPEKEDGSP
SFKLEHLTAANGLGHDKAHDAMSDVYATIALARLIKEKQPKLFDYYFRLRRKQAVAEQIDVLAMQPLVHISSKIPATQGC
ATLIAPVAHHMRNKNAVICVNLAMDIQPLIDLDVDALRTRLYTKREDLANDELPVPVKQIHLNKCPFVANAKTLDDANAE
RLGIDKAFAREQYRLLKQHPEIREKLTALFEEEPQGMSNDPDYSLYSGGFFSPADRAKMDIIRNTSPEHLAALELQFDDT
RLPEMLFRYRARNYPLTLSYDESLRWREFCQARLNDPDYVIRLENLLEETTKDEKKQKLLGALCQYLQSL
>Mature_470_residues
MENYIQPTIFWHDYETFGASPAKDRPAQFAGVRTDLDLNIIDEPVTFYCRLSPDYLPAPEAILITGITPQLANRQGLPET
EFMGRIQAIFSRPNTCVAGYNSLRFDDEVSRYGFYRNFIDPYAREWQQGNSRWDIIDLVRACYALRPEGINWPEKEDGSP
SFKLEHLTAANGLGHDKAHDAMSDVYATIALARLIKEKQPKLFDYYFRLRRKQAVAEQIDVLAMQPLVHISSKIPATQGC
ATLIAPVAHHMRNKNAVICVNLAMDIQPLIDLDVDALRTRLYTKREDLANDELPVPVKQIHLNKCPFVANAKTLDDANAE
RLGIDKAFAREQYRLLKQHPEIREKLTALFEEEPQGMSNDPDYSLYSGGFFSPADRAKMDIIRNTSPEHLAALELQFDDT
RLPEMLFRYRARNYPLTLSYDESLRWREFCQARLNDPDYVIRLENLLEETTKDEKKQKLLGALCQYLQSL

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=470, Percent_Identity=52.7659574468085, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54057; Mature: 54057

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYIQPTIFWHDYETFGASPAKDRPAQFAGVRTDLDLNIIDEPVTFYCRLSPDYLPAPE
CCCCCCCEEEEECHHHHCCCCCCCCCCHHCCCEECCCCEEECCCEEEEEEECCCCCCCCC
AILITGITPQLANRQGLPETEFMGRIQAIFSRPNTCVAGYNSLRFDDEVSRYGFYRNFID
EEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
PYAREWQQGNSRWDIIDLVRACYALRPEGINWPEKEDGSPSFKLEHLTAANGLGHDKAHD
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCHHHH
AMSDVYATIALARLIKEKQPKLFDYYFRLRRKQAVAEQIDVLAMQPLVHISSKIPATQGC
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ATLIAPVAHHMRNKNAVICVNLAMDIQPLIDLDVDALRTRLYTKREDLANDELPVPVKQI
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
HLNKCPFVANAKTLDDANAERLGIDKAFAREQYRLLKQHPEIREKLTALFEEEPQGMSND
CCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCC
PDYSLYSGGFFSPADRAKMDIIRNTSPEHLAALELQFDDTRLPEMLFRYRARNYPLTLSY
CCCCEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEC
DESLRWREFCQARLNDPDYVIRLENLLEETTKDEKKQKLLGALCQYLQSL
CCCCHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENYIQPTIFWHDYETFGASPAKDRPAQFAGVRTDLDLNIIDEPVTFYCRLSPDYLPAPE
CCCCCCCEEEEECHHHHCCCCCCCCCCHHCCCEECCCCEEECCCEEEEEEECCCCCCCCC
AILITGITPQLANRQGLPETEFMGRIQAIFSRPNTCVAGYNSLRFDDEVSRYGFYRNFID
EEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
PYAREWQQGNSRWDIIDLVRACYALRPEGINWPEKEDGSPSFKLEHLTAANGLGHDKAHD
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCHHHH
AMSDVYATIALARLIKEKQPKLFDYYFRLRRKQAVAEQIDVLAMQPLVHISSKIPATQGC
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ATLIAPVAHHMRNKNAVICVNLAMDIQPLIDLDVDALRTRLYTKREDLANDELPVPVKQI
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
HLNKCPFVANAKTLDDANAERLGIDKAFAREQYRLLKQHPEIREKLTALFEEEPQGMSND
CCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCC
PDYSLYSGGFFSPADRAKMDIIRNTSPEHLAALELQFDDTRLPEMLFRYRARNYPLTLSY
CCCCEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEC
DESLRWREFCQARLNDPDYVIRLENLLEETTKDEKKQKLLGALCQYLQSL
CCCCHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]