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The map label for this gene is minC

Identifier: 119775065

GI number: 119775065

Start: 2357627

End: 2358301

Strand: Direct

Name: minC

Synonym: Sama_1930

Alternate gene names: 119775065

Gene position: 2357627-2358301 (Clockwise)

Preceding gene: 119775061

Following gene: 119775066

Centisome position: 54.75

GC content: 53.48

Gene sequence:

>675_bases
ATGCGAAAAGCAAGCCTTGAATTAAAGGGATCTTCTTTTACGCTGTCGGTATTGCATATCAATACCTCCGATTTGGACAG
CATCACCTTGGACCTCGACAAGAAACTGGCGCAAGCGCCACAGTTTTTTATCGGAGCCCCTTTGGTACTGAATCTATCCG
CCGTCGAAGACGGAAAATTGGACTTGGCAGCACTTAAAGATCTGCTGGTATCACGTCAACTGGTGATTGTTGGTGTGACC
GGCGCCAGTGAAGCACTGTCTGAGCAGGCCAAGGCCTGTGGGCTTGCCTCGGTCAAAGCCGGTAAGCAGACACAGATGCC
CTCTCCCCCATCCGAGCCCAGAACCACCCGTATCGTGCGGCAAAACGTCCGTTCCGGGCAGCAGATCTACGTTAAAAATG
GCGATTTGATTATCTTCGGCGCCGTCGGAAACGGCGCCGAGGTGATTGCCGATGGCAGTATTCATATTTACGGCGCACTC
AGGGGCAAGGCCATGGCCGGTGCCAATGGCGAGCGGGATGCAGTTATCCTGGCCAGCCACCTGGAGCCCGAACTTATTTC
CATCGCGGGTCAATACTGGCTGACTGAAAATTTACAAAAGCATGGTGTGACCGCGAAAAGCGGCTGTGTGCGCCTCGATG
GTGACTCACTAACAGTAGAAGCACTGCCATTGTGA

Upstream 100 bases:

>100_bases
ATCAAACTTGCCAGTGATTGGGGCACACTATAACATGGGCTCTTTAGAAAAAAATGCAGATCAGCGCGAGACTGATTAAT
TTCTGGAGCAGATTACGGGG

Downstream 100 bases:

>100_bases
TGGGGCAGAATTAAGGGATAAAAATTAGCATGGCACAGATTATTGTTGTCACTTCCGGAAAAGGCGGCGTAGGTAAAACC
ACATCAAGTGCCGCCATTGC

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRKASLELKGSSFTLSVLHINTSDLDSITLDLDKKLAQAPQFFIGAPLVLNLSAVEDGKLDLAALKDLLVSRQLVIVGVT
GASEALSEQAKACGLASVKAGKQTQMPSPPSEPRTTRIVRQNVRSGQQIYVKNGDLIIFGAVGNGAEVIADGSIHIYGAL
RGKAMAGANGERDAVILASHLEPELISIAGQYWLTENLQKHGVTAKSGCVRLDGDSLTVEALPL

Sequences:

>Translated_224_residues
MRKASLELKGSSFTLSVLHINTSDLDSITLDLDKKLAQAPQFFIGAPLVLNLSAVEDGKLDLAALKDLLVSRQLVIVGVT
GASEALSEQAKACGLASVKAGKQTQMPSPPSEPRTTRIVRQNVRSGQQIYVKNGDLIIFGAVGNGAEVIADGSIHIYGAL
RGKAMAGANGERDAVILASHLEPELISIAGQYWLTENLQKHGVTAKSGCVRLDGDSLTVEALPL
>Mature_224_residues
MRKASLELKGSSFTLSVLHINTSDLDSITLDLDKKLAQAPQFFIGAPLVLNLSAVEDGKLDLAALKDLLVSRQLVIVGVT
GASEALSEQAKACGLASVKAGKQTQMPSPPSEPRTTRIVRQNVRSGQQIYVKNGDLIIFGAVGNGAEVIADGSIHIYGAL
RGKAMAGANGERDAVILASHLEPELISIAGQYWLTENLQKHGVTAKSGCVRLDGDSLTVEALPL

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=233, Percent_Identity=39.9141630901288, Blast_Score=164, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_SHEAM (A1S6X9)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927805.1
- ProteinModelPortal:   A1S6X9
- SMR:   A1S6X9
- STRING:   A1S6X9
- GeneID:   4604180
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1930
- NMPDR:   fig|326297.7.peg.1813
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- OMA:   KGDTKAR
- PhylomeDB:   A1S6X9
- ProtClustDB:   PRK04804
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 23594; Mature: 23594

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKASLELKGSSFTLSVLHINTSDLDSITLDLDKKLAQAPQFFIGAPLVLNLSAVEDGKL
CCCCEEEECCCEEEEEEEEECCCCCCEEEEEHHHHHHHCCCEEECCCEEEEEEECCCCCC
DLAALKDLLVSRQLVIVGVTGASEALSEQAKACGLASVKAGKQTQMPSPPSEPRTTRIVR
CHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHH
QNVRSGQQIYVKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGANGERDAVILASH
HHHCCCCEEEEECCCEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCCEEEEECC
LEPELISIAGQYWLTENLQKHGVTAKSGCVRLDGDSLTVEALPL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEECC
>Mature Secondary Structure
MRKASLELKGSSFTLSVLHINTSDLDSITLDLDKKLAQAPQFFIGAPLVLNLSAVEDGKL
CCCCEEEECCCEEEEEEEEECCCCCCEEEEEHHHHHHHCCCEEECCCEEEEEEECCCCCC
DLAALKDLLVSRQLVIVGVTGASEALSEQAKACGLASVKAGKQTQMPSPPSEPRTTRIVR
CHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHH
QNVRSGQQIYVKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGANGERDAVILASH
HHHCCCCEEEEECCCEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCCEEEEECC
LEPELISIAGQYWLTENLQKHGVTAKSGCVRLDGDSLTVEALPL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA