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The map label for this gene is fadE [H]

Identifier: 119774950

GI number: 119774950

Start: 2210044

End: 2212323

Strand: Reverse

Name: fadE [H]

Synonym: Sama_1815

Alternate gene names: 119774950

Gene position: 2212323-2210044 (Counterclockwise)

Preceding gene: 119774951

Following gene: 119774947

Centisome position: 51.38

GC content: 52.02

Gene sequence:

>2280_bases
ATGACCATCTTGTTGTTATTGATAATCGCAGCGGTGATAGTGTTGTTCGCGGTGAAAGATTTACGGATGAAGTTTATCAC
TCAGCCGGTTTTTGCCTTTTTTAAACGTGTGTTGCCACCGCTTTCTGACACCGAACGTGAAGCCATGGAAGCCGGTGATG
TGTGGTGGGAAGGTGAATTATTCCGCGGCAAACCCAATTGGGAAGCCCTGCACGCCTATGGCAAACCAACCTTGTCAGCT
GAGGAAAAAGAGTTTCTCGATAATCAGGTAATGACCGCATTGTCGATGATTGACGATTTTGACATCGTTCATAACCGCAA
AGACCTGCCACCCGAGCTGTGGGACTACTTCAAGAAAGAAGGCTTCTTCGCGCTTATTATTCCGAAAAAGTACGGTGGTA
AAGGTTTCTCGGCCTATGCCAACTCCACCATTGTTGCCAAGCTGGCCAGTCGCAGTGTCAGCGCTGCGGTAACCGTGATG
GTACCCAACTCGCTGGGGCCCGGTGAGCTTTTGACTCATTACGGTACCAAGGAGCAAAAAGATTTCTGGTTACCTTCGCT
TGCCAAAGGCGAAGAAATTCCCTGTTTCGCCCTGACCGGACCTGAAGCGGGCTCTGATGCGGGCGCAATTCCCGATGTCG
GCGTGGTCAAAAACGGCGAGTTTAATGGCAACGAGGTTCTTGGCGTCGAACTGACCTGGAACAAGCGCTATATTACCCTG
GCGCCCGTTGCGACTGTGTTGGGTCTCGCGTTTCAAATGAAAGACCCTGATGGTCTGCTGGGAGATAAGAAACATATCGG
CATTACCTGTGCGCTTATTCCAACCAGTCATCCCGGCGTTGAAATCGGTAATCGCCACAATCCACTGAACATGGCCTTTA
TGAATGGAACTACCCGGGGGGACAAAGTATTTATTCCGTTGGATTGGATAATCGGTGGGCCTCAGTATGCAGGTAAAGGC
TGGCGTATGCTGGTTGAGTGCCTGTCGGCCGGTCGGGGTATTTCACTGCCTGCGCTGGCTACTGCCTCGGGTCATGTGAC
CACCAAAACCACCACTGCCTATAGTTATGTGCGTAAACAGTTCGGCATGTCCATCGGTCACTTTGAAGGTGTGCAGGAAG
CGTTGGCCCGCATCATAGGTAACACCTATCAGTTGGAAGCAGCACGGCGTTTAACCACTACAGGAATTGATCTTAAAGTA
AAACCCTCTGTGGTGACGGCCATTGCCAAATACCATATGACAGAGATGGGCAGGGCAGTGATGGACGATGCCATGGACAT
TCAGTCCGGTAAAGGCATCCAGCTGGGACCCAAAAACTATCTGGGTCATGCCTATATGGCCAATCCAATCTCTATTACGG
TTGAAGGAGCCAATATCCTCACCCGTAGCCTGATGATCTTCGGGCAAGGCGCTACACGCTGCCATCCCTATGTGCTGGCT
GAAATGGAAGCCGCCGGAATGGAAGACATAGATGCAGCCCTGGAGCGCTTTGACGATTTGCTGCTCGGACACATGGGTTA
CGCGACCCGCAATGCCTTGTCGAGTCTGTTTTCAGCGCTGACTGCCAGCCGTTTTGCCCAGTCGCCTGTAAGTGGGGATA
CCAAACGTTATTACCAACATATGGGCCGCATGTCGGCAGCGCTGGCCATTATGACTGATATGGCCATGCTTATCCTGGGT
GGCGAACTCAAGCGCCGTGAAATGCTCTCTGCCCGTTTGGGTGATGTGTTGTCTGAGCTGTATCTGGCATCGGCTACGCT
GAAGCTTTTTGAAGACAATGGCCGCCAACATGATGATTTGCCCACTGTACATTATGTGATGCAGACCCGTCTGATGAAGG
CCGCGAAGGCACTGGAAGATGCACTGAGAAACTTTCCGCTGCGTCCGGTAGGTTGGCTCTTGCGCGCATTGGTGTTCCCA
CTCGGTAACCACTTCAAAGGCCCGTCTGACAAACTGGCTACTCAGGTCGTGGAGGCCATGCTTAAACCCGGCCCGGCCCG
TGAGCGTCTGACGTTCCTGTGCCCATCATTCGATGGCGACAAGGGCGGTATTGCCGAAGTTGAAGAAGCCTTCCTGGCAC
AATACGAGTGTCGTAGCATATACAAAAAACTGCGTTCCGCTCAAAAAGAAGGCAAGTTGAAAGGCAAAGGCGTCAGTGCC
GCATTGCTCAGTCAAGCGGTTGAACAAGGCGTTATCAGTCAGGAAGAGCACGATAAAGTACTGAAGGCTGACGAACTGCG
CCTGGCCGCTGTCAATGTTGACGAGTTCAGTGCCTTGTAA

Upstream 100 bases:

>100_bases
AAGAACAGAACGACATAGAGTCTGTTATCCGTAAAGTCATTCCCTATATGGCCGCCGGCGTTGCCGTCCCGGTCAGCAAG
GCATAACAGGAGTAATTGCC

Downstream 100 bases:

>100_bases
CAGGTAAAACAACCTGTGTTAGTTCAGCCATAGCAGGTTTAAATAGAAGAAAAGGGTACGCCAATGCGTACCTTTTTTAT
TGAGCCGAACTGTGGGTTTG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MTILLLLIIAAVIVLFAVKDLRMKFITQPVFAFFKRVLPPLSDTEREAMEAGDVWWEGELFRGKPNWEALHAYGKPTLSA
EEKEFLDNQVMTALSMIDDFDIVHNRKDLPPELWDYFKKEGFFALIIPKKYGGKGFSAYANSTIVAKLASRSVSAAVTVM
VPNSLGPGELLTHYGTKEQKDFWLPSLAKGEEIPCFALTGPEAGSDAGAIPDVGVVKNGEFNGNEVLGVELTWNKRYITL
APVATVLGLAFQMKDPDGLLGDKKHIGITCALIPTSHPGVEIGNRHNPLNMAFMNGTTRGDKVFIPLDWIIGGPQYAGKG
WRMLVECLSAGRGISLPALATASGHVTTKTTTAYSYVRKQFGMSIGHFEGVQEALARIIGNTYQLEAARRLTTTGIDLKV
KPSVVTAIAKYHMTEMGRAVMDDAMDIQSGKGIQLGPKNYLGHAYMANPISITVEGANILTRSLMIFGQGATRCHPYVLA
EMEAAGMEDIDAALERFDDLLLGHMGYATRNALSSLFSALTASRFAQSPVSGDTKRYYQHMGRMSAALAIMTDMAMLILG
GELKRREMLSARLGDVLSELYLASATLKLFEDNGRQHDDLPTVHYVMQTRLMKAAKALEDALRNFPLRPVGWLLRALVFP
LGNHFKGPSDKLATQVVEAMLKPGPARERLTFLCPSFDGDKGGIAEVEEAFLAQYECRSIYKKLRSAQKEGKLKGKGVSA
ALLSQAVEQGVISQEEHDKVLKADELRLAAVNVDEFSAL

Sequences:

>Translated_759_residues
MTILLLLIIAAVIVLFAVKDLRMKFITQPVFAFFKRVLPPLSDTEREAMEAGDVWWEGELFRGKPNWEALHAYGKPTLSA
EEKEFLDNQVMTALSMIDDFDIVHNRKDLPPELWDYFKKEGFFALIIPKKYGGKGFSAYANSTIVAKLASRSVSAAVTVM
VPNSLGPGELLTHYGTKEQKDFWLPSLAKGEEIPCFALTGPEAGSDAGAIPDVGVVKNGEFNGNEVLGVELTWNKRYITL
APVATVLGLAFQMKDPDGLLGDKKHIGITCALIPTSHPGVEIGNRHNPLNMAFMNGTTRGDKVFIPLDWIIGGPQYAGKG
WRMLVECLSAGRGISLPALATASGHVTTKTTTAYSYVRKQFGMSIGHFEGVQEALARIIGNTYQLEAARRLTTTGIDLKV
KPSVVTAIAKYHMTEMGRAVMDDAMDIQSGKGIQLGPKNYLGHAYMANPISITVEGANILTRSLMIFGQGATRCHPYVLA
EMEAAGMEDIDAALERFDDLLLGHMGYATRNALSSLFSALTASRFAQSPVSGDTKRYYQHMGRMSAALAIMTDMAMLILG
GELKRREMLSARLGDVLSELYLASATLKLFEDNGRQHDDLPTVHYVMQTRLMKAAKALEDALRNFPLRPVGWLLRALVFP
LGNHFKGPSDKLATQVVEAMLKPGPARERLTFLCPSFDGDKGGIAEVEEAFLAQYECRSIYKKLRSAQKEGKLKGKGVSA
ALLSQAVEQGVISQEEHDKVLKADELRLAAVNVDEFSAL
>Mature_758_residues
TILLLLIIAAVIVLFAVKDLRMKFITQPVFAFFKRVLPPLSDTEREAMEAGDVWWEGELFRGKPNWEALHAYGKPTLSAE
EKEFLDNQVMTALSMIDDFDIVHNRKDLPPELWDYFKKEGFFALIIPKKYGGKGFSAYANSTIVAKLASRSVSAAVTVMV
PNSLGPGELLTHYGTKEQKDFWLPSLAKGEEIPCFALTGPEAGSDAGAIPDVGVVKNGEFNGNEVLGVELTWNKRYITLA
PVATVLGLAFQMKDPDGLLGDKKHIGITCALIPTSHPGVEIGNRHNPLNMAFMNGTTRGDKVFIPLDWIIGGPQYAGKGW
RMLVECLSAGRGISLPALATASGHVTTKTTTAYSYVRKQFGMSIGHFEGVQEALARIIGNTYQLEAARRLTTTGIDLKVK
PSVVTAIAKYHMTEMGRAVMDDAMDIQSGKGIQLGPKNYLGHAYMANPISITVEGANILTRSLMIFGQGATRCHPYVLAE
MEAAGMEDIDAALERFDDLLLGHMGYATRNALSSLFSALTASRFAQSPVSGDTKRYYQHMGRMSAALAIMTDMAMLILGG
ELKRREMLSARLGDVLSELYLASATLKLFEDNGRQHDDLPTVHYVMQTRLMKAAKALEDALRNFPLRPVGWLLRALVFPL
GNHFKGPSDKLATQVVEAMLKPGPARERLTFLCPSFDGDKGGIAEVEEAFLAQYECRSIYKKLRSAQKEGKLKGKGVSAA
LLSQAVEQGVISQEEHDKVLKADELRLAAVNVDEFSAL

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=392, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI4557233, Length=320, Percent_Identity=30, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI4501859, Length=382, Percent_Identity=29.0575916230367, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=24.9350649350649, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=24.9350649350649, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI226958412, Length=302, Percent_Identity=25.8278145695364, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI226958414, Length=274, Percent_Identity=26.6423357664234, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081702, Length=755, Percent_Identity=53.112582781457, Blast_Score=808, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985184, Length=381, Percent_Identity=26.7716535433071, Blast_Score=106, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=284, Percent_Identity=32.3943661971831, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=349, Percent_Identity=26.647564469914, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=282, Percent_Identity=28.7234042553192, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=26.530612244898, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=330, Percent_Identity=26.969696969697, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=363, Percent_Identity=25.068870523416, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=298, Percent_Identity=25.503355704698, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=247, Percent_Identity=29.5546558704453, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=370, Percent_Identity=26.2162162162162, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356377, Length=336, Percent_Identity=27.3809523809524, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363737, Length=386, Percent_Identity=25.9067357512953, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24666513, Length=344, Percent_Identity=27.3255813953488, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 83087; Mature: 82956

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILLLLIIAAVIVLFAVKDLRMKFITQPVFAFFKRVLPPLSDTEREAMEAGDVWWEGEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEECCEE
FRGKPNWEALHAYGKPTLSAEEKEFLDNQVMTALSMIDDFDIVHNRKDLPPELWDYFKKE
ECCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
GFFALIIPKKYGGKGFSAYANSTIVAKLASRSVSAAVTVMVPNSLGPGELLTHYGTKEQK
CCEEEEEECCCCCCCCHHHCCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHCCCCCCC
DFWLPSLAKGEEIPCFALTGPEAGSDAGAIPDVGVVKNGEFNGNEVLGVELTWNKRYITL
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCEEEEH
APVATVLGLAFQMKDPDGLLGDKKHIGITCALIPTSHPGVEIGNRHNPLNMAFMNGTTRG
HHHHHHHHHHHEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
DKVFIPLDWIIGGPQYAGKGWRMLVECLSAGRGISLPALATASGHVTTKTTTAYSYVRKQ
CEEEEEEHEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCEEECHHHHHHHHHHH
FGMSIGHFEGVQEALARIIGNTYQLEAARRLTTTGIDLKVKPSVVTAIAKYHMTEMGRAV
HCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHH
MDDAMDIQSGKGIQLGPKNYLGHAYMANPISITVEGANILTRSLMIFGQGATRCHPYVLA
HHHHHHCCCCCCCEECCHHHCCCEEECCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEEE
EMEAAGMEDIDAALERFDDLLLGHMGYATRNALSSLFSALTASRFAQSPVSGDTKRYYQH
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MGRMSAALAIMTDMAMLILGGELKRREMLSARLGDVLSELYLASATLKLFEDNGRQHDDL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTVHYVMQTRLMKAAKALEDALRNFPLRPVGWLLRALVFPLGNHFKGPSDKLATQVVEAM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LKPGPARERLTFLCPSFDGDKGGIAEVEEAFLAQYECRSIYKKLRSAQKEGKLKGKGVSA
HCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ALLSQAVEQGVISQEEHDKVLKADELRLAAVNVDEFSAL
HHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECHHHHCCC
>Mature Secondary Structure 
TILLLLIIAAVIVLFAVKDLRMKFITQPVFAFFKRVLPPLSDTEREAMEAGDVWWEGEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEECCEE
FRGKPNWEALHAYGKPTLSAEEKEFLDNQVMTALSMIDDFDIVHNRKDLPPELWDYFKKE
ECCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
GFFALIIPKKYGGKGFSAYANSTIVAKLASRSVSAAVTVMVPNSLGPGELLTHYGTKEQK
CCEEEEEECCCCCCCCHHHCCCHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHCCCCCCC
DFWLPSLAKGEEIPCFALTGPEAGSDAGAIPDVGVVKNGEFNGNEVLGVELTWNKRYITL
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCEEEEH
APVATVLGLAFQMKDPDGLLGDKKHIGITCALIPTSHPGVEIGNRHNPLNMAFMNGTTRG
HHHHHHHHHHHEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
DKVFIPLDWIIGGPQYAGKGWRMLVECLSAGRGISLPALATASGHVTTKTTTAYSYVRKQ
CEEEEEEHEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCEEECHHHHHHHHHHH
FGMSIGHFEGVQEALARIIGNTYQLEAARRLTTTGIDLKVKPSVVTAIAKYHMTEMGRAV
HCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHH
MDDAMDIQSGKGIQLGPKNYLGHAYMANPISITVEGANILTRSLMIFGQGATRCHPYVLA
HHHHHHCCCCCCCEECCHHHCCCEEECCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEEE
EMEAAGMEDIDAALERFDDLLLGHMGYATRNALSSLFSALTASRFAQSPVSGDTKRYYQH
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MGRMSAALAIMTDMAMLILGGELKRREMLSARLGDVLSELYLASATLKLFEDNGRQHDDL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTVHYVMQTRLMKAAKALEDALRNFPLRPVGWLLRALVFPLGNHFKGPSDKLATQVVEAM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LKPGPARERLTFLCPSFDGDKGGIAEVEEAFLAQYECRSIYKKLRSAQKEGKLKGKGVSA
HCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ALLSQAVEQGVISQEEHDKVLKADELRLAAVNVDEFSAL
HHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]