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The map label for this gene is nrdB [H]

Identifier: 119774862

GI number: 119774862

Start: 2112584

End: 2113759

Strand: Reverse

Name: nrdB [H]

Synonym: Sama_1727

Alternate gene names: 119774862

Gene position: 2113759-2112584 (Counterclockwise)

Preceding gene: 119774863

Following gene: 119774861

Centisome position: 49.09

GC content: 49.83

Gene sequence:

>1176_bases
GTGTTAACAGGGGGCTTTGCCCCCTTTTACCGGAATAGAGAAATCATGGCTTACACTACTTTTTGTCAAACTCCCAACGA
TGCAACCCGCGAACCTATGTTTTTCGGCCAGTCCGTTAACGTTGCCCGTTACGATCAACAGCGCTATGAAGTATTTGAAA
AGCTGATTGAAAAGCAGCTGTCATTCTTCTGGCGACCAGAAGAAGTAGACGTAAGCCGTGACAAAATCGATTTTGGAAAG
CTGCCTGATCACGAAAGGCACATCTTTATTTCCAATCTCAAGTACCAAACCTTACTTGACTCTATTCAGGGCCGCAGTCC
TAACGTTGCCTTCCTGCCTTTGGTGTCGCTGCCAGAGCTGGAAACCTGGATTGAAACCTGGTCTTTCTCTGAAACTATCC
ACTCACGGTCATACACCCATATCATTCGCAATATTGTGAACGACCCTTCGTCGGTGTTTGACGATATTGTCGTCAATGAA
GAGATCCTCAAGCGTGCCGGCGATATTTCGGCCTATTATGACGAGCTCATCAAGCTGACCCAGATTTACCATCTGCACGG
CGAAGGCACCCACACGGTGGATGGCCATGTGGTCGATGTAACTGTACGCGCCCTGAAAAAGGCTCTCTACCTGTGCATGA
TGTCGGTGAACGCCCTGGAAGCCATTCGTTTCTACGTCAGCTTTGCCTGTTCGTTCGCCTTTGCCGAGCGCAAGTTGATG
GAAGGCAACGCCAAAATCATCCGTCTTATCGCCCGAGATGAAGCACTGCACCTTAACTCGACTCAGCATATCCTCAACAT
CATGCAGGGCGGTAAGGACGATGCAGAAATGGCAGAAATCGCCATTGAGTGTCAGCAGGAAGCCTACGATCTGTTCCTGC
GCGCTGCCGAGCAGGAAAAAGAATGGGCCAAGTACCTCTTTAAAGATGGCTCCATGATTGGCCTGAACGAGCAAATTCTG
TGTCAGTACGTGGAGTACATCACAAACCAGCGCATGAAGTCGGTCAACCTGCCTCTGCCATACCCAGAATCCACCAACCC
GCTGCCGTGGATGAAAAACTGGCTCGAGAGCGATGCTGTTCAGGTGGCACCGCAGGAAGTGGAAGTATCCTCTTACCTGG
TAGGCCAGATTGACGCTTCCGTCGATGAAAATGAGTTCTCCGACTTTGATCTTTAA

Upstream 100 bases:

>100_bases
GACCGATCAGCATGATGACATTGCTGTGGTTGAAAAAGAGGACGACGGCTGCGCCGGTGGTGCCTGTAAGATTTAACACA
GGCAAATACAAGGAAATTTG

Downstream 100 bases:

>100_bases
AAAGGCGCCCATCGTCAGCCTTCAGGGACAACCTGTGCTGCTGTTCAATGGACAGCAGCAGTCTTTGCTGGAGGCGCTCG
AGATCAAGAAAGTCCGTGTC

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLTGGFAPFYRNREIMAYTTFCQTPNDATREPMFFGQSVNVARYDQQRYEVFEKLIEKQLSFFWRPEEVDVSRDKIDFGK
LPDHERHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPSSVFDDIVVNE
EILKRAGDISAYYDELIKLTQIYHLHGEGTHTVDGHVVDVTVRALKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLM
EGNAKIIRLIARDEALHLNSTQHILNIMQGGKDDAEMAEIAIECQQEAYDLFLRAAEQEKEWAKYLFKDGSMIGLNEQIL
CQYVEYITNQRMKSVNLPLPYPESTNPLPWMKNWLESDAVQVAPQEVEVSSYLVGQIDASVDENEFSDFDL

Sequences:

>Translated_391_residues
MLTGGFAPFYRNREIMAYTTFCQTPNDATREPMFFGQSVNVARYDQQRYEVFEKLIEKQLSFFWRPEEVDVSRDKIDFGK
LPDHERHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPSSVFDDIVVNE
EILKRAGDISAYYDELIKLTQIYHLHGEGTHTVDGHVVDVTVRALKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLM
EGNAKIIRLIARDEALHLNSTQHILNIMQGGKDDAEMAEIAIECQQEAYDLFLRAAEQEKEWAKYLFKDGSMIGLNEQIL
CQYVEYITNQRMKSVNLPLPYPESTNPLPWMKNWLESDAVQVAPQEVEVSSYLVGQIDASVDENEFSDFDL
>Mature_391_residues
MLTGGFAPFYRNREIMAYTTFCQTPNDATREPMFFGQSVNVARYDQQRYEVFEKLIEKQLSFFWRPEEVDVSRDKIDFGK
LPDHERHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPSSVFDDIVVNE
EILKRAGDISAYYDELIKLTQIYHLHGEGTHTVDGHVVDVTVRALKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLM
EGNAKIIRLIARDEALHLNSTQHILNIMQGGKDDAEMAEIAIECQQEAYDLFLRAAEQEKEWAKYLFKDGSMIGLNEQIL
CQYVEYITNQRMKSVNLPLPYPESTNPLPWMKNWLESDAVQVAPQEVEVSSYLVGQIDASVDENEFSDFDL

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1788567, Length=376, Percent_Identity=76.8617021276596, Blast_Score=620, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 45168; Mature: 45168

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTGGFAPFYRNREIMAYTTFCQTPNDATREPMFFGQSVNVARYDQQRYEVFEKLIEKQL
CCCCCCCHHHCCCEEEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
SFFWRPEEVDVSRDKIDFGKLPDHERHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPEL
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCHH
ETWIETWSFSETIHSRSYTHIIRNIVNDPSSVFDDIVVNEEILKRAGDISAYYDELIKLT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
QIYHLHGEGTHTVDGHVVDVTVRALKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLM
HHHEECCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGNAKIIRLIARDEALHLNSTQHILNIMQGGKDDAEMAEIAIECQQEAYDLFLRAAEQEK
CCCHHEEEEEECCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWAKYLFKDGSMIGLNEQILCQYVEYITNQRMKSVNLPLPYPESTNPLPWMKNWLESDAV
HHHHHHHCCCCEECCCHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCHHHHHHHHCCHH
QVAPQEVEVSSYLVGQIDASVDENEFSDFDL
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTGGFAPFYRNREIMAYTTFCQTPNDATREPMFFGQSVNVARYDQQRYEVFEKLIEKQL
CCCCCCCHHHCCCEEEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
SFFWRPEEVDVSRDKIDFGKLPDHERHIFISNLKYQTLLDSIQGRSPNVAFLPLVSLPEL
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCHH
ETWIETWSFSETIHSRSYTHIIRNIVNDPSSVFDDIVVNEEILKRAGDISAYYDELIKLT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
QIYHLHGEGTHTVDGHVVDVTVRALKKALYLCMMSVNALEAIRFYVSFACSFAFAERKLM
HHHEECCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGNAKIIRLIARDEALHLNSTQHILNIMQGGKDDAEMAEIAIECQQEAYDLFLRAAEQEK
CCCHHEEEEEECCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWAKYLFKDGSMIGLNEQILCQYVEYITNQRMKSVNLPLPYPESTNPLPWMKNWLESDAV
HHHHHHHCCCCEECCCHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCHHHHHHHHCCHH
QVAPQEVEVSSYLVGQIDASVDENEFSDFDL
HCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]