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The map label for this gene is pabB [H]

Identifier: 119774823

GI number: 119774823

Start: 2060661

End: 2062076

Strand: Reverse

Name: pabB [H]

Synonym: Sama_1687

Alternate gene names: 119774823

Gene position: 2062076-2060661 (Counterclockwise)

Preceding gene: 119774829

Following gene: 119774822

Centisome position: 47.89

GC content: 52.75

Gene sequence:

>1416_bases
ATGTTTCCACCCCTGCCCACTCGTATAAATCATGCACAGCTCGCCGTAAAAACCCTCGATTGGACCGCATCCACCAGCGA
CATTTTTACCCCATTGGCCAGTCAGCCATGGTCAATGCTGCTTGACTCGGCCGATGCACCGCACATGGACGCCCACTGGG
ACATTTTGGTGGCAGCCCCTGTCGCTACGTTAAAAGTGTACGAGAGCCACTCCGAACTCACCTATGCAGGCAACACACTG
AGACTGGACACCTCTGAGTGCCCTTTTTCACAGTTGCAATCGGTCCAGCATGCACTATTCAGCGTTCAAAAAAATACATC
ACTCCCCTTCGCCGGTGGCGCATTAGGCAGTTTTAACTATGATTTAGGCAGGCGCATTGAGCGACTACCCAGTACGGCTC
TGGACGATATTAATCTGCCATTAGCCTGTATTGGCTTTTACGACTGGGCGCTTATGCGAAGCTATCAATCTGATTCATGG
CAACTGGTACATTATCTCGGTGATGACGCATTAAACGAGACACTGGCATGGCTTGAGCAGCAGCGCGACTTTGCCCAAGC
CGGGGCGGAGTCTAACACCAGCTTCTCGCTGCTGACGGAGTTTACCCCCCAAATCACCCGAGACCAGTACCAGCAAAAAT
TCAATCAGGTGCAATCTTATTTGGCGAGTGGTGACTGCTATCAGATAAACCTGACCCAAAGGTTCAGCGCTGATTATCAG
GGAAGCGAGTGGCAGGCCTACCTCAAACTGCGTTCTGCCAATGTGGCGCCCTTCTCTGCCTTTGTCCGGCTTGAAGAAGG
CGCCATTTTGTCCATCTCGCCGGAACGGTTTATCAAACTTGACGGCAGACAGGTGGAAACCAAGCCTATCAAGGGCACCT
TGCCAAGATTGCCCGACCCGGACGCCGATAAAACCAATGCCATTTTGCTGAAAGCCTCGCCCAAAGACAGGGCCGAAAAC
CTGATGATTGTGGATCTGCTGCGAAATGATATTGGCCGGGTAGCAAGCCCGGGGAGTGTTCGGGTGCCCAAGCTTTTTGA
AGTGGAAAGCTTCCCTGCCGTGCATCATTTGGTCAGTACAGTAACCGCGCAACTTGCCGAAAACAAAGATGCCTTTGATT
TATTGAGAGCAGCCTTCCCGGGCGGCTCTATTACCGGCGCCCCCAAAATCCGCGCCATGGAAATTATTGAAGAGCTTGAG
CCATCCCGGCGCAGCATTTACTGTGGCTCCATCGGTTATATCAGCCAGCACGGTAATATGGATACCAGCATCACCATACG
CACCCTGGCGGCTGTCGATGGCAAACTGTACTGCTGGGCCGGTGGGGGCGTGGTGGCCGACTCAATTGCCGACAGCGAGT
ATCAGGAAACCTTCGACAAGATCAGCCGTATTCTACCGATACTGGAACAGGAATAA

Upstream 100 bases:

>100_bases
CGTGGGACGAGGCCTGTTGTTTTGGTTAATCCTTTTTCGGCCAATATGATACTCTGTTGCAAATCTTTGGGCTACATCAC
AAGTTGAATAAGGTTAATCG

Downstream 100 bases:

>100_bases
TTGTTTATGCCCTTTAACGGCGCCGATGCCATTAGTGTTGACAAACTCAGGTTGCACTTTTCATTGCAGCCACTTCGTCA
TGCCATAGTGTCGGCCCCGC

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MFPPLPTRINHAQLAVKTLDWTASTSDIFTPLASQPWSMLLDSADAPHMDAHWDILVAAPVATLKVYESHSELTYAGNTL
RLDTSECPFSQLQSVQHALFSVQKNTSLPFAGGALGSFNYDLGRRIERLPSTALDDINLPLACIGFYDWALMRSYQSDSW
QLVHYLGDDALNETLAWLEQQRDFAQAGAESNTSFSLLTEFTPQITRDQYQQKFNQVQSYLASGDCYQINLTQRFSADYQ
GSEWQAYLKLRSANVAPFSAFVRLEEGAILSISPERFIKLDGRQVETKPIKGTLPRLPDPDADKTNAILLKASPKDRAEN
LMIVDLLRNDIGRVASPGSVRVPKLFEVESFPAVHHLVSTVTAQLAENKDAFDLLRAAFPGGSITGAPKIRAMEIIEELE
PSRRSIYCGSIGYISQHGNMDTSITIRTLAAVDGKLYCWAGGGVVADSIADSEYQETFDKISRILPILEQE

Sequences:

>Translated_471_residues
MFPPLPTRINHAQLAVKTLDWTASTSDIFTPLASQPWSMLLDSADAPHMDAHWDILVAAPVATLKVYESHSELTYAGNTL
RLDTSECPFSQLQSVQHALFSVQKNTSLPFAGGALGSFNYDLGRRIERLPSTALDDINLPLACIGFYDWALMRSYQSDSW
QLVHYLGDDALNETLAWLEQQRDFAQAGAESNTSFSLLTEFTPQITRDQYQQKFNQVQSYLASGDCYQINLTQRFSADYQ
GSEWQAYLKLRSANVAPFSAFVRLEEGAILSISPERFIKLDGRQVETKPIKGTLPRLPDPDADKTNAILLKASPKDRAEN
LMIVDLLRNDIGRVASPGSVRVPKLFEVESFPAVHHLVSTVTAQLAENKDAFDLLRAAFPGGSITGAPKIRAMEIIEELE
PSRRSIYCGSIGYISQHGNMDTSITIRTLAAVDGKLYCWAGGGVVADSIADSEYQETFDKISRILPILEQE
>Mature_471_residues
MFPPLPTRINHAQLAVKTLDWTASTSDIFTPLASQPWSMLLDSADAPHMDAHWDILVAAPVATLKVYESHSELTYAGNTL
RLDTSECPFSQLQSVQHALFSVQKNTSLPFAGGALGSFNYDLGRRIERLPSTALDDINLPLACIGFYDWALMRSYQSDSW
QLVHYLGDDALNETLAWLEQQRDFAQAGAESNTSFSLLTEFTPQITRDQYQQKFNQVQSYLASGDCYQINLTQRFSADYQ
GSEWQAYLKLRSANVAPFSAFVRLEEGAILSISPERFIKLDGRQVETKPIKGTLPRLPDPDADKTNAILLKASPKDRAEN
LMIVDLLRNDIGRVASPGSVRVPKLFEVESFPAVHHLVSTVTAQLAENKDAFDLLRAAFPGGSITGAPKIRAMEIIEELE
PSRRSIYCGSIGYISQHGNMDTSITIRTLAAVDGKLYCWAGGGVVADSIADSEYQETFDKISRILPILEQE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=458, Percent_Identity=56.7685589519651, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1787518, Length=389, Percent_Identity=31.1053984575836, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786809, Length=221, Percent_Identity=27.1493212669683, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082077, Length=206, Percent_Identity=25.2427184466019, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=448, Percent_Identity=32.8125, Blast_Score=196, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=409, Percent_Identity=29.5843520782396, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 52233; Mature: 52233

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPPLPTRINHAQLAVKTLDWTASTSDIFTPLASQPWSMLLDSADAPHMDAHWDILVAAP
CCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEECC
VATLKVYESHSELTYAGNTLRLDTSECPFSQLQSVQHALFSVQKNTSLPFAGGALGSFNY
CEEEEEECCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DLGRRIERLPSTALDDINLPLACIGFYDWALMRSYQSDSWQLVHYLGDDALNETLAWLEQ
HHHHHHHHCCCHHHCCCCCCEEEHHHHHHHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHH
QRDFAQAGAESNTSFSLLTEFTPQITRDQYQQKFNQVQSYLASGDCYQINLTQRFSADYQ
HHHHHHCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCC
GSEWQAYLKLRSANVAPFSAFVRLEEGAILSISPERFIKLDGRQVETKPIKGTLPRLPDP
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEECHHHEEEECCCEEECCCCCCCCCCCCCC
DADKTNAILLKASPKDRAENLMIVDLLRNDIGRVASPGSVRVPKLFEVESFPAVHHLVST
CCCCCCEEEEECCCCCHHCCEEEHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHH
VTAQLAENKDAFDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSIYCGSIGYISQHGNM
HHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEECCCCCC
DTSITIRTLAAVDGKLYCWAGGGVVADSIADSEYQETFDKISRILPILEQE
CCEEEEEEEEECCCEEEEEECCCEEEHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFPPLPTRINHAQLAVKTLDWTASTSDIFTPLASQPWSMLLDSADAPHMDAHWDILVAAP
CCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEECC
VATLKVYESHSELTYAGNTLRLDTSECPFSQLQSVQHALFSVQKNTSLPFAGGALGSFNY
CEEEEEECCCCCEEECCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DLGRRIERLPSTALDDINLPLACIGFYDWALMRSYQSDSWQLVHYLGDDALNETLAWLEQ
HHHHHHHHCCCHHHCCCCCCEEEHHHHHHHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHH
QRDFAQAGAESNTSFSLLTEFTPQITRDQYQQKFNQVQSYLASGDCYQINLTQRFSADYQ
HHHHHHCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCC
GSEWQAYLKLRSANVAPFSAFVRLEEGAILSISPERFIKLDGRQVETKPIKGTLPRLPDP
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEECHHHEEEECCCEEECCCCCCCCCCCCCC
DADKTNAILLKASPKDRAENLMIVDLLRNDIGRVASPGSVRVPKLFEVESFPAVHHLVST
CCCCCCEEEEECCCCCHHCCEEEHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHH
VTAQLAENKDAFDLLRAAFPGGSITGAPKIRAMEIIEELEPSRRSIYCGSIGYISQHGNM
HHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEECCCCCC
DTSITIRTLAAVDGKLYCWAGGGVVADSIADSEYQETFDKISRILPILEQE
CCEEEEEEEEECCCEEEEEECCCEEEHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]