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The map label for this gene is kdsB

Identifier: 119774775

GI number: 119774775

Start: 2005097

End: 2005834

Strand: Reverse

Name: kdsB

Synonym: Sama_1639

Alternate gene names: 119774775

Gene position: 2005834-2005097 (Counterclockwise)

Preceding gene: 119774776

Following gene: 119774774

Centisome position: 46.58

GC content: 55.01

Gene sequence:

>738_bases
ATGAACGTGACCCTGTTGATCCCTGCCCGCTACGGCTCCAGCCGTTTTCCCGGCAAGCCATTGGCTCCCATCAATGGTAA
ACCCATGATCCAGCACGTCTATGAACGTGCTGCACTGGCGAAGGGATTAAATGCCATCTACGTGGCCACGGACGATGAAC
GTATTAAAGATGCCGTTGAATCCTTTGGCGGCAAAGTGGTAATGACAGGTGCCGATGCTGCATCGGGTACCGACCGTATC
GAAGACGCCATCACCCAGCTGGGGCTGGCCGACGATGATTTGGTGATTAACCTCCAGGGCGACCAACCCCTGATTGACCC
TATCTCCATCGAGCAGATTGTCGAGCTGTTCCGTCGCCATCCCGGCGAGTTTGAAATGGCTACCCTGGGTTACCAGATAA
GCGACAAGGCCGAGCTTGACGATCCCAAGCACGTAAAGATGGTGTTCGACAACGACATGTATGCGCTCTACTTCTCCCGC
GCCTGCATTCCTTTTGGCCGTGACGTGAGCGAATACCCTGTGTACAAACATTTGGGTGTATATGCCTACACCCGCCGTTT
TGTGCACACCTTCAACAGCCTGCCGCTGGGACGCCTGGAAGATCTGGAAAAGCTCGAGCAGCTGCGTGCCCTGGAATACG
GTCACAGGATTAAAGTCGCCATCAGCGCCTTCGACTCACCGGAAGTGGACACACCGGAGGATATCCGCCGCTGTGAAAAT
CGTCTGAAGGTAGACTGA

Upstream 100 bases:

>100_bases
AAAGTGACCGACGAGATGCTGACCAAACTGTACCGTCGCATCTAGTCTTGTTTCCGGGCTCCTTCGGGAGCCCGCTTTGT
TAGAGTCCAGGAATTTTTTG

Downstream 100 bases:

>100_bases
TGAACGCCTCCGGCATGTCAAATCTGGAAGTCTGGCTCATCATATTGCTGGTGATTGGGGTCATTTTTTCAAACATCGCC
GTACTCAAGTACAGCGCCAA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLNAIYVATDDERIKDAVESFGGKVVMTGADAASGTDRI
EDAITQLGLADDDLVINLQGDQPLIDPISIEQIVELFRRHPGEFEMATLGYQISDKAELDDPKHVKMVFDNDMYALYFSR
ACIPFGRDVSEYPVYKHLGVYAYTRRFVHTFNSLPLGRLEDLEKLEQLRALEYGHRIKVAISAFDSPEVDTPEDIRRCEN
RLKVD

Sequences:

>Translated_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLNAIYVATDDERIKDAVESFGGKVVMTGADAASGTDRI
EDAITQLGLADDDLVINLQGDQPLIDPISIEQIVELFRRHPGEFEMATLGYQISDKAELDDPKHVKMVFDNDMYALYFSR
ACIPFGRDVSEYPVYKHLGVYAYTRRFVHTFNSLPLGRLEDLEKLEQLRALEYGHRIKVAISAFDSPEVDTPEDIRRCEN
RLKVD
>Mature_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLNAIYVATDDERIKDAVESFGGKVVMTGADAASGTDRI
EDAITQLGLADDDLVINLQGDQPLIDPISIEQIVELFRRHPGEFEMATLGYQISDKAELDDPKHVKMVFDNDMYALYFSR
ACIPFGRDVSEYPVYKHLGVYAYTRRFVHTFNSLPLGRLEDLEKLEQLRALEYGHRIKVAISAFDSPEVDTPEDIRRCEN
RLKVD

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=252, Percent_Identity=43.2539682539683, Blast_Score=191, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_SHEAM (A1S639)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927515.1
- ProteinModelPortal:   A1S639
- SMR:   A1S639
- STRING:   A1S639
- GeneID:   4603890
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1639
- NMPDR:   fig|326297.7.peg.1548
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- PhylomeDB:   A1S639
- ProtClustDB:   PRK05450
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27562; Mature: 27562

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLNAIYVATDDERIKDAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
SFGGKVVMTGADAASGTDRIEDAITQLGLADDDLVINLQGDQPLIDPISIEQIVELFRRH
HHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHC
PGEFEMATLGYQISDKAELDDPKHVKMVFDNDMYALYFSRACIPFGRDVSEYPVYKHLGV
CCCEEEEEECEEECCCCCCCCCCEEEEEECCCEEEEEEHHHCCCCCCCCCCCCHHHHHHH
YAYTRRFVHTFNSLPLGRLEDLEKLEQLRALEYGHRIKVAISAFDSPEVDTPEDIRRCEN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
RLKVD
HCCCC
>Mature Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLNAIYVATDDERIKDAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
SFGGKVVMTGADAASGTDRIEDAITQLGLADDDLVINLQGDQPLIDPISIEQIVELFRRH
HHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHC
PGEFEMATLGYQISDKAELDDPKHVKMVFDNDMYALYFSRACIPFGRDVSEYPVYKHLGV
CCCEEEEEECEEECCCCCCCCCCEEEEEECCCEEEEEEHHHCCCCCCCCCCCCHHHHHHH
YAYTRRFVHTFNSLPLGRLEDLEKLEQLRALEYGHRIKVAISAFDSPEVDTPEDIRRCEN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
RLKVD
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA