Click here to switch to the map view.

The map label for this gene is prc [H]

Identifier: 119774722

GI number: 119774722

Start: 1928153

End: 1930198

Strand: Direct

Name: prc [H]

Synonym: Sama_1585

Alternate gene names: 119774722

Gene position: 1928153-1930198 (Clockwise)

Preceding gene: 119774721

Following gene: 119774723

Centisome position: 44.78

GC content: 52.3

Gene sequence:

>2046_bases
ATGCGAAAACTATCTCTGGCGGTATCCATTGCCGGGATCCTGGTAGGATCTTCTGCGTGGGCCATAGCGCCTGCCATTCA
AATCGATGAGCTGCCCTCTCTGGTGCAGGAGCCTCAGCACAAGGTGGCCTCCAAGCGGGTAGCGGATCTTTTTACCCGCT
CACACTACCACAGGTTCAGCCTGGACGATGCCTTCTCCGAACAGATTTTCGACCGTTACCTTAAGCAGTTGGATTACCGT
CGTAATGTGCTGACTCAAGCCGATGTGCAGAACTTCGAAAAGTATCGCCATCAGTTTGATGACATGCTCAAAAACGGCGA
TATGACAGGCGCCTACGACATGTTCGATCTGGCCCAAAAGCGCCGGTATGAAGGTTTTGTTTACGCGCTGAGTCTGCTAG
ATAAAGAAATGGACTTTTCTCAGGCGGGTGACAAGTACCAGTATGACCGTGAAGACGCTCCCTGGGCTAAGGACGAAGCC
GAAATTCAGGAATTATGGCGTCAGCGCGTTAAATATGATGCGTTGAACCTTAAGTTGACCGGTAAAAACTGGACTGAAAT
CGTTGATGTGCTGCAAAAGCGCTACAACAACGCCATCAAACGCCTGGGCCAAACCCAGAGCGAAGATGTATTCCAGACAG
TAATGAACGCGTTTTCACGCAGCATCGAGCCCCACACCAGCTATCTTTCCCCACGCAATGCCGAGCGTTTCCAGATGGAA
ATGAACCTCAGCCTCGAGGGCATTGGCGCTGTGTTGCAAATGGATGACGACTACACCGTTATCAAGAGCATGGTTGCAGG
TGGCCCTGCTGCCAGCAGTGAAAAATTGTCCCCCGATGACCGCATCATAGGTGTAGGTCAGGAAGGTGGTGCCGTGGTGG
ACGTGATTGGCTGGCGTCTCGATGACGTAGTCGACCTTATCAAGGGCCCCAAAGGCAGCAAGGTCACCTTGCAAATTCTA
CCCAAGAAAGGTGGCTCCAACGCCAAACCAGTCGAAGTGACCCTGGTCAGGGATAAAATTCGCCTTGAAGATCGGGCTGC
TACGTCCAAAGTGATTGAGCCCAACGAGGGGCAGTATGCCAACCGTAAGGTAGGCGTTATTCAGATCCCCGGTTTCTACA
TGAACCTGTCTCAGGATGTGGCTAAAGAGCTGCAAACCCTGAAAGAGGCGAAAGTAGAAGGTGTGATTATTGATCTGCGT
GGCAATGGTGGTGGCGCCTTGACCGAAGCTGTGTTGCTGACAGGGCTCTTTATCGATATGGGGCCTGTGGTGCAGGTACG
CGATGCCAATGGCCGCGTTTCCCAGCACAGAGACAACGATGGCAAGGTCACTTATTCAGGTCCCCTGACTGTGATGGTGG
ACCGTTACAGTGCTTCTGCGTCTGAAATTTTTGCGGCCGCCTTGCAGGACTACCAGCGTGCGCTGATTGTTGGTGAGTCA
ACCTTCGGTAAGGGCACAGTTCAGCAGCATAAGGGCCTGGCGCGCATATACGATCTGTATGAAAAGCCAGTTGGCCATGT
GCAGTACACAATTCAGAAGTTTTACCGTATCAACGGTGGCAGCACCCAGCTTAAAGGGGTTACACCGGATATCCCGTTCC
CCAGTGCCCTCGAGCCTGGAGAATACGGCGAGGCTGAAGAAGATAACGCACTGCCCTGGGATAAGGTACCTGTGGCCCAG
TACAGCACGGTGGATGCTATCAGTGCCCCCCTCATTGCTGAACTGGATGCCAAACATCAGGGTCGCATCAAGTCAGATGT
GGAATTTGGCTATATTTATCAGGATATTGCTGAATATAAAAAGCACCACGATGAAAAGTCTGTATCACTGGTGGAAAGTG
AGCGCATTGCTGAGCGTGAAGCTGATGACAAGAAACAGCTCGATCGCACCAATGAACGCCGCACCCGCGCCGGCCTCGAT
AAGGTAGCGAGCCTGGATGATATCGAGAAAGATATCGAAGCGCCGGATCCACTGCTGGATGAAACTGCCTATATCACACT
GGATCTGGTTGATGCGGGCAAACTTGCGGCAACCAGCAAGCACTGA

Upstream 100 bases:

>100_bases
AGGGCGATGTGCATGTACAGCTGGACTCAGGCTTGACAGTGAAAGTCCGCGCCGAGTATATACTGCTGTAATTCATTGAA
GTTTAAGGAGTAGCTTGTTG

Downstream 100 bases:

>100_bases
TTTCCGACTTTGATATAAAAAACGCGCTCCGGCGCGTTTTTTTTCAGGATAAGCCGTATCCTCTTCTTACCCATAGAATT
TGTCGAACACACTCTTAAAG

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MRKLSLAVSIAGILVGSSAWAIAPAIQIDELPSLVQEPQHKVASKRVADLFTRSHYHRFSLDDAFSEQIFDRYLKQLDYR
RNVLTQADVQNFEKYRHQFDDMLKNGDMTGAYDMFDLAQKRRYEGFVYALSLLDKEMDFSQAGDKYQYDREDAPWAKDEA
EIQELWRQRVKYDALNLKLTGKNWTEIVDVLQKRYNNAIKRLGQTQSEDVFQTVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAVLQMDDDYTVIKSMVAGGPAASSEKLSPDDRIIGVGQEGGAVVDVIGWRLDDVVDLIKGPKGSKVTLQIL
PKKGGSNAKPVEVTLVRDKIRLEDRAATSKVIEPNEGQYANRKVGVIQIPGFYMNLSQDVAKELQTLKEAKVEGVIIDLR
GNGGGALTEAVLLTGLFIDMGPVVQVRDANGRVSQHRDNDGKVTYSGPLTVMVDRYSASASEIFAAALQDYQRALIVGES
TFGKGTVQQHKGLARIYDLYEKPVGHVQYTIQKFYRINGGSTQLKGVTPDIPFPSALEPGEYGEAEEDNALPWDKVPVAQ
YSTVDAISAPLIAELDAKHQGRIKSDVEFGYIYQDIAEYKKHHDEKSVSLVESERIAEREADDKKQLDRTNERRTRAGLD
KVASLDDIEKDIEAPDPLLDETAYITLDLVDAGKLAATSKH

Sequences:

>Translated_681_residues
MRKLSLAVSIAGILVGSSAWAIAPAIQIDELPSLVQEPQHKVASKRVADLFTRSHYHRFSLDDAFSEQIFDRYLKQLDYR
RNVLTQADVQNFEKYRHQFDDMLKNGDMTGAYDMFDLAQKRRYEGFVYALSLLDKEMDFSQAGDKYQYDREDAPWAKDEA
EIQELWRQRVKYDALNLKLTGKNWTEIVDVLQKRYNNAIKRLGQTQSEDVFQTVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAVLQMDDDYTVIKSMVAGGPAASSEKLSPDDRIIGVGQEGGAVVDVIGWRLDDVVDLIKGPKGSKVTLQIL
PKKGGSNAKPVEVTLVRDKIRLEDRAATSKVIEPNEGQYANRKVGVIQIPGFYMNLSQDVAKELQTLKEAKVEGVIIDLR
GNGGGALTEAVLLTGLFIDMGPVVQVRDANGRVSQHRDNDGKVTYSGPLTVMVDRYSASASEIFAAALQDYQRALIVGES
TFGKGTVQQHKGLARIYDLYEKPVGHVQYTIQKFYRINGGSTQLKGVTPDIPFPSALEPGEYGEAEEDNALPWDKVPVAQ
YSTVDAISAPLIAELDAKHQGRIKSDVEFGYIYQDIAEYKKHHDEKSVSLVESERIAEREADDKKQLDRTNERRTRAGLD
KVASLDDIEKDIEAPDPLLDETAYITLDLVDAGKLAATSKH
>Mature_681_residues
MRKLSLAVSIAGILVGSSAWAIAPAIQIDELPSLVQEPQHKVASKRVADLFTRSHYHRFSLDDAFSEQIFDRYLKQLDYR
RNVLTQADVQNFEKYRHQFDDMLKNGDMTGAYDMFDLAQKRRYEGFVYALSLLDKEMDFSQAGDKYQYDREDAPWAKDEA
EIQELWRQRVKYDALNLKLTGKNWTEIVDVLQKRYNNAIKRLGQTQSEDVFQTVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAVLQMDDDYTVIKSMVAGGPAASSEKLSPDDRIIGVGQEGGAVVDVIGWRLDDVVDLIKGPKGSKVTLQIL
PKKGGSNAKPVEVTLVRDKIRLEDRAATSKVIEPNEGQYANRKVGVIQIPGFYMNLSQDVAKELQTLKEAKVEGVIIDLR
GNGGGALTEAVLLTGLFIDMGPVVQVRDANGRVSQHRDNDGKVTYSGPLTVMVDRYSASASEIFAAALQDYQRALIVGES
TFGKGTVQQHKGLARIYDLYEKPVGHVQYTIQKFYRINGGSTQLKGVTPDIPFPSALEPGEYGEAEEDNALPWDKVPVAQ
YSTVDAISAPLIAELDAKHQGRIKSDVEFGYIYQDIAEYKKHHDEKSVSLVESERIAEREADDKKQLDRTNERRTRAGLD
KVASLDDIEKDIEAPDPLLDETAYITLDLVDAGKLAATSKH

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=668, Percent_Identity=55.8383233532934, Blast_Score=714, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 76140; Mature: 76140

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure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CCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]