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The map label for this gene is ggt [H]

Identifier: 119774703

GI number: 119774703

Start: 1909555

End: 1911327

Strand: Reverse

Name: ggt [H]

Synonym: Sama_1566

Alternate gene names: 119774703

Gene position: 1911327-1909555 (Counterclockwise)

Preceding gene: 119774704

Following gene: 119774701

Centisome position: 44.39

GC content: 55.89

Gene sequence:

>1773_bases
ATGAAACCACGGCCCGGTGCCTTTACCTTAAAAGGGCTGACACTCGCCCTTGCCATCGCCCTGCCCTTTGCAGCGACATT
TACCGCAGAGGCCAAACTGCCCACCAAGCCCACCTTGGATGACAGTGCCATCTTCAGTGAAATGGCCACCGCCCAGCCAA
TATTTGGCAAGTACGGTATGGTCTCAAGTCAGGAAGCGCTGGCCACCCGCATCGGCGTGGATATCCTCAAAAAAGGCGGC
AATGCCGTGGATGCGGCTGTTGCCGTAGGTTTTGCCCTGGCGGTAACCCTCCCCCGGGCCGGCAATCTCGGCGGCGGCGG
TTTTATGCTGGTGCATCTGGCCAAAGACAATAAAACCATCGCCATCGATTACCGTGAAACGGCTCCAAAAGCCTCAAAAC
GCGATATGTTCCTCGATGAAGCCGGCAATGCCGTGGATGAGTTGAGCCGCAGCCATGGGCTTGCTGTGGGCGTACCCGGC
ACAGTAATGGGCATGGAACTGGCACTGAAAAAATACGGCACCATGAGCCTTTCGGAGGTTATTGCCCCTGCGATACAGCT
CGCCCAAGACGGTGTGGAAGTCACCGCCGAGCTGGCGAGCTCCTTGGCAGGACTGCAAAACTGGATTGCCAGATGGCCCA
CTTCTGCAGAGGTTTTTTACCCCAACGAGGGGCAAAACCTAACAGTGGGTCAGCGTCTGGTACAAAAAGATTTGGCCGAG
AGCTTAAAACGCATCAGCAAGGCCGGTAGCAAAGGCTTTTATGAAGGAGAAACCGCCGAAAAACTGGTGGCTGCGGTACA
GGAGGCCGGTGGCATCATGACCCTGGACGACCTAAAAGCCTACAAGGTGATGGAGCGCGAGCCGGTGCGTGGCAATTACC
GAGGGCTGGAAGTCGTCTCCATGCCACCGCCAAGCTCAGGTGGCATTCACATCATTCAAATGCTCAATGTGCTTGAGCAC
TTCCCCATGGGCGAGCTTGGCCATAACAGTGCCCAAAGCATTCACTTTATGGCCGAAACCATGAAGCGCGCCTATGCCGA
TCGCAGTGAGTATCTGGGCGACCCTGACTTTGTGAACGTGCCGGTCCAGGCGCTGACCAGCAAGGCCTATGGCGATGCGA
TTGCCAAGACCATAGCGGCCAATAAGGCGACCCCGTCCGATGACATCAAACCCGGAAAACTTGCCCCCTATGAGAGCGAC
CAGACTACCCACTATTCGGTGGTCGATAAATGGGGCAATGCGGTATCGAACACCTATACCCTGAACTTCAGCTACGGCTC
AGGCATGGTAGCCAGGGGTACCGGCATCCTCCTCAACAACGAGATGGATGATTTTGCCGCCAAACCCGGCAGTCCCAATG
GTTACGGATTGCTCGGTGGCGATGCCAATGCGGTTGAACCACAAAAGCGGCCGCTGTCATCCATGAGCCCCACCATAGTG
ATGAAAGACGGCAAGCCCTTTATCGTTACAGGCAGCCCCGGTGGTTCACGTATCATCAATACTGTGCTGCAAATCATTAT
GAACGTGGTGGATTACGACCTGAACATCGCCGAGGCCAGCATTGCGCCGCGGATTCATCATCAGTGGTATCCCGATGAAA
TCCGCACCGAGCGCAGCCTGAATGTGGATACCCGGCGTCTGCTTGAATCCATGGGCCACAAGGTCAACGTCAAACATGCC
ATGGGCTCGACCCAGTCAATTGTGGTGACTGAAGAAGGCATCTATGGCGCCTCAGACACACGTCAAAGCGCCAGCGAAAC
CCTGGGTTACTGA

Upstream 100 bases:

>100_bases
AGACAAAAACCGTTGCAAAGCCAAACCGCAGCAGGCACAGTGACAACTTCATAAAATGTAAAAAATACAACACAAAGAAC
ACGTTTTTGGGGGATCCAAC

Downstream 100 bases:

>100_bases
CGTACGTTAAAACACGCGGACTGAAGCGCGTTGAATCGCACCTTTAATAAAAAAGCGCCTTTGAGGCGCTTTTTTACTTC
CTGAAAACCGGCAGGCTGTA

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MKPRPGAFTLKGLTLALAIALPFAATFTAEAKLPTKPTLDDSAIFSEMATAQPIFGKYGMVSSQEALATRIGVDILKKGG
NAVDAAVAVGFALAVTLPRAGNLGGGGFMLVHLAKDNKTIAIDYRETAPKASKRDMFLDEAGNAVDELSRSHGLAVGVPG
TVMGMELALKKYGTMSLSEVIAPAIQLAQDGVEVTAELASSLAGLQNWIARWPTSAEVFYPNEGQNLTVGQRLVQKDLAE
SLKRISKAGSKGFYEGETAEKLVAAVQEAGGIMTLDDLKAYKVMEREPVRGNYRGLEVVSMPPPSSGGIHIIQMLNVLEH
FPMGELGHNSAQSIHFMAETMKRAYADRSEYLGDPDFVNVPVQALTSKAYGDAIAKTIAANKATPSDDIKPGKLAPYESD
QTTHYSVVDKWGNAVSNTYTLNFSYGSGMVARGTGILLNNEMDDFAAKPGSPNGYGLLGGDANAVEPQKRPLSSMSPTIV
MKDGKPFIVTGSPGGSRIINTVLQIIMNVVDYDLNIAEASIAPRIHHQWYPDEIRTERSLNVDTRRLLESMGHKVNVKHA
MGSTQSIVVTEEGIYGASDTRQSASETLGY

Sequences:

>Translated_590_residues
MKPRPGAFTLKGLTLALAIALPFAATFTAEAKLPTKPTLDDSAIFSEMATAQPIFGKYGMVSSQEALATRIGVDILKKGG
NAVDAAVAVGFALAVTLPRAGNLGGGGFMLVHLAKDNKTIAIDYRETAPKASKRDMFLDEAGNAVDELSRSHGLAVGVPG
TVMGMELALKKYGTMSLSEVIAPAIQLAQDGVEVTAELASSLAGLQNWIARWPTSAEVFYPNEGQNLTVGQRLVQKDLAE
SLKRISKAGSKGFYEGETAEKLVAAVQEAGGIMTLDDLKAYKVMEREPVRGNYRGLEVVSMPPPSSGGIHIIQMLNVLEH
FPMGELGHNSAQSIHFMAETMKRAYADRSEYLGDPDFVNVPVQALTSKAYGDAIAKTIAANKATPSDDIKPGKLAPYESD
QTTHYSVVDKWGNAVSNTYTLNFSYGSGMVARGTGILLNNEMDDFAAKPGSPNGYGLLGGDANAVEPQKRPLSSMSPTIV
MKDGKPFIVTGSPGGSRIINTVLQIIMNVVDYDLNIAEASIAPRIHHQWYPDEIRTERSLNVDTRRLLESMGHKVNVKHA
MGSTQSIVVTEEGIYGASDTRQSASETLGY
>Mature_590_residues
MKPRPGAFTLKGLTLALAIALPFAATFTAEAKLPTKPTLDDSAIFSEMATAQPIFGKYGMVSSQEALATRIGVDILKKGG
NAVDAAVAVGFALAVTLPRAGNLGGGGFMLVHLAKDNKTIAIDYRETAPKASKRDMFLDEAGNAVDELSRSHGLAVGVPG
TVMGMELALKKYGTMSLSEVIAPAIQLAQDGVEVTAELASSLAGLQNWIARWPTSAEVFYPNEGQNLTVGQRLVQKDLAE
SLKRISKAGSKGFYEGETAEKLVAAVQEAGGIMTLDDLKAYKVMEREPVRGNYRGLEVVSMPPPSSGGIHIIQMLNVLEH
FPMGELGHNSAQSIHFMAETMKRAYADRSEYLGDPDFVNVPVQALTSKAYGDAIAKTIAANKATPSDDIKPGKLAPYESD
QTTHYSVVDKWGNAVSNTYTLNFSYGSGMVARGTGILLNNEMDDFAAKPGSPNGYGLLGGDANAVEPQKRPLSSMSPTIV
MKDGKPFIVTGSPGGSRIINTVLQIIMNVVDYDLNIAEASIAPRIHHQWYPDEIRTERSLNVDTRRLLESMGHKVNVKHA
MGSTQSIVVTEEGIYGASDTRQSASETLGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=539, Percent_Identity=33.0241187384045, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI73915090, Length=539, Percent_Identity=33.0241187384045, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI73915096, Length=539, Percent_Identity=33.0241187384045, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI73915094, Length=539, Percent_Identity=33.0241187384045, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI113429324, Length=529, Percent_Identity=31.9470699432892, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI113429326, Length=534, Percent_Identity=31.6479400749064, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI109148539, Length=590, Percent_Identity=31.6949152542373, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI153266885, Length=569, Percent_Identity=28.1195079086116, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI153266901, Length=570, Percent_Identity=28.0701754385965, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI153266907, Length=569, Percent_Identity=26.5377855887522, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI30581157, Length=229, Percent_Identity=34.9344978165939, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI30581155, Length=229, Percent_Identity=34.9344978165939, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI218505805, Length=228, Percent_Identity=32.4561403508772, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI310124095, Length=228, Percent_Identity=30.7017543859649, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1789856, Length=540, Percent_Identity=59.6296296296296, Blast_Score=638, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72000294, Length=546, Percent_Identity=33.5164835164835, Blast_Score=265, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI212646519, Length=546, Percent_Identity=33.5164835164835, Blast_Score=265, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17506189, Length=592, Percent_Identity=31.4189189189189, Blast_Score=240, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17542894, Length=544, Percent_Identity=30.5147058823529, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193208247, Length=565, Percent_Identity=29.2035398230088, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193208245, Length=565, Percent_Identity=29.2035398230088, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17564448, Length=437, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI72001497, Length=352, Percent_Identity=25.2840909090909, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI72001495, Length=352, Percent_Identity=25.2840909090909, Blast_Score=85, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323330, Length=517, Percent_Identity=29.7872340425532, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24642670, Length=539, Percent_Identity=31.5398886827458, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24642666, Length=539, Percent_Identity=31.5398886827458, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI45551474, Length=539, Percent_Identity=31.5398886827458, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI161077880, Length=539, Percent_Identity=31.5398886827458, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI161077878, Length=539, Percent_Identity=31.5398886827458, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI161077496, Length=507, Percent_Identity=31.5581854043393, Blast_Score=215, Evalue=8e-56,
Organism=Drosophila melanogaster, GI18859893, Length=515, Percent_Identity=31.4563106796116, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI18859741, Length=538, Percent_Identity=27.6951672862454, Blast_Score=173, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 63031; Mature: 63031

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRPGAFTLKGLTLALAIALPFAATFTAEAKLPTKPTLDDSAIFSEMATAQPIFGKYGM
CCCCCCCEEHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
VSSQEALATRIGVDILKKGGNAVDAAVAVGFALAVTLPRAGNLGGGGFMLVHLAKDNKTI
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCEE
AIDYRETAPKASKRDMFLDEAGNAVDELSRSHGLAVGVPGTVMGMELALKKYGTMSLSEV
EEEECCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCCHHHH
IAPAIQLAQDGVEVTAELASSLAGLQNWIARWPTSAEVFYPNEGQNLTVGQRLVQKDLAE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHH
SLKRISKAGSKGFYEGETAEKLVAAVQEAGGIMTLDDLKAYKVMEREPVRGNYRGLEVVS
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCEEEEE
MPPPSSGGIHIIQMLNVLEHFPMGELGHNSAQSIHFMAETMKRAYADRSEYLGDPDFVNV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
PVQALTSKAYGDAIAKTIAANKATPSDDIKPGKLAPYESDQTTHYSVVDKWGNAVSNTYT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEE
LNFSYGSGMVARGTGILLNNEMDDFAAKPGSPNGYGLLGGDANAVEPQKRPLSSMSPTIV
EEEECCCCEEECCCEEEECCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEE
MKDGKPFIVTGSPGGSRIINTVLQIIMNVVDYDLNIAEASIAPRIHHQWYPDEIRTERSL
EECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCHHHCCCCCC
NVDTRRLLESMGHKVNVKHAMGSTQSIVVTEEGIYGASDTRQSASETLGY
CHHHHHHHHHCCCEEEEHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKPRPGAFTLKGLTLALAIALPFAATFTAEAKLPTKPTLDDSAIFSEMATAQPIFGKYGM
CCCCCCCEEHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
VSSQEALATRIGVDILKKGGNAVDAAVAVGFALAVTLPRAGNLGGGGFMLVHLAKDNKTI
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCCEE
AIDYRETAPKASKRDMFLDEAGNAVDELSRSHGLAVGVPGTVMGMELALKKYGTMSLSEV
EEEECCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCCHHHH
IAPAIQLAQDGVEVTAELASSLAGLQNWIARWPTSAEVFYPNEGQNLTVGQRLVQKDLAE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHH
SLKRISKAGSKGFYEGETAEKLVAAVQEAGGIMTLDDLKAYKVMEREPVRGNYRGLEVVS
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCEEEEE
MPPPSSGGIHIIQMLNVLEHFPMGELGHNSAQSIHFMAETMKRAYADRSEYLGDPDFVNV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
PVQALTSKAYGDAIAKTIAANKATPSDDIKPGKLAPYESDQTTHYSVVDKWGNAVSNTYT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEE
LNFSYGSGMVARGTGILLNNEMDDFAAKPGSPNGYGLLGGDANAVEPQKRPLSSMSPTIV
EEEECCCCEEECCCEEEECCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEE
MKDGKPFIVTGSPGGSRIINTVLQIIMNVVDYDLNIAEASIAPRIHHQWYPDEIRTERSL
EECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCHHHCCCCCC
NVDTRRLLESMGHKVNVKHAMGSTQSIVVTEEGIYGASDTRQSASETLGY
CHHHHHHHHHCCCEEEEHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]