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The map label for this gene is dapA1 [H]

Identifier: 119774668

GI number: 119774668

Start: 1861570

End: 1862484

Strand: Reverse

Name: dapA1 [H]

Synonym: Sama_1531

Alternate gene names: 119774668

Gene position: 1862484-1861570 (Counterclockwise)

Preceding gene: 119774671

Following gene: 119774667

Centisome position: 43.25

GC content: 54.75

Gene sequence:

>915_bases
ATGAAAGTTAACTGGCAAGGCGTATATCCAGCGATTTCTACCCAATTCAATGAAGATGGCTCTATCAATTTCGCCTCCAA
CACCCGTATGTTGGAACAACTTATCCTGGATGGCATTAACGGCATCATCGCCCTGGGTACCATAGGTGAAAACGCGTCTT
TAAGCGCTGACGAAAAACGCGCCTTCCTTAAGCACACGGTCGAAACCGTTGCCGGACGCATTCCCGTGATTGCCGGTTGT
ACCGAAAATACGGCCCAGTTAGCCATCCAGTATGTCCAGGACGTAGAAGCCATCGGGGTTGATGGGGTTATGTTGCTGCC
GGCCGTGGTTTATCGTGGCACCGACCGTGAAGTGCTGACCCACTACCAGATGGTGGCCCGCGCCACCAGACTGCCTATCA
TGATCTATAACAATCCAGTGAGTTACGGCGTTGATATTAATTTGGACATGACCGCCATTCTCGCCAACGAGCCCAACATA
GTGGCGATTAAGGAATCCACCACGGACACCCGCCGCCTCACCGAGTTGCAAAGCCGCTTCGGCGATCGTTTCACCCTGTT
CTGCGGCGTGGACGATATCGCGCTTGAGTCTCTGTTATTGGGTGCCACCGGCTGGATTTCCGGCCTGACCAACGTGTTCC
CCCGTGAGTCGGTCACCCTCTATAAGCTCGCCCGCGCCGGTCGCATGGAAGAAGCCCGTGAAATCTATCGCTGGTTTATG
CCACTGCTGCGCCTCGATACCATTCCAACTCTGGTGCAGTGCATCAAGTTTGCCGAGCAACTGGCCGGTCGTGGCAGCGA
GCAGGTGCGCATGCCCCGCATGACGCTCATCGGCGATGAGCGGGCCTATGTTGAGAACGTCGTGGGAGAAGCCATGGCCA
ATCGCATCGATTTATCCAAATACAATCTGGACTGA

Upstream 100 bases:

>100_bases
ATATACTATAACTTTACGCAATGCCGAGCGCATAACCCTGTGTCCGAATTGATAAGGCGGACAGCGTTAGACAAAAACAA
GACTATTTTGAGGTTTAAAA

Downstream 100 bases:

>100_bases
CAGGCCAAGAGCGATAATAACAATATTACCGGAGCTCTACGACTATGATGAAAGGTACATTTTTCTGCGTTGATGCTCAT
ACCTGCGGTAACCCAGTGCG

Product: dihydrodipicolinate synthetase family protein

Products: NA

Alternate protein names: DHDPS 1 [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKVNWQGVYPAISTQFNEDGSINFASNTRMLEQLILDGINGIIALGTIGENASLSADEKRAFLKHTVETVAGRIPVIAGC
TENTAQLAIQYVQDVEAIGVDGVMLLPAVVYRGTDREVLTHYQMVARATRLPIMIYNNPVSYGVDINLDMTAILANEPNI
VAIKESTTDTRRLTELQSRFGDRFTLFCGVDDIALESLLLGATGWISGLTNVFPRESVTLYKLARAGRMEEAREIYRWFM
PLLRLDTIPTLVQCIKFAEQLAGRGSEQVRMPRMTLIGDERAYVENVVGEAMANRIDLSKYNLD

Sequences:

>Translated_304_residues
MKVNWQGVYPAISTQFNEDGSINFASNTRMLEQLILDGINGIIALGTIGENASLSADEKRAFLKHTVETVAGRIPVIAGC
TENTAQLAIQYVQDVEAIGVDGVMLLPAVVYRGTDREVLTHYQMVARATRLPIMIYNNPVSYGVDINLDMTAILANEPNI
VAIKESTTDTRRLTELQSRFGDRFTLFCGVDDIALESLLLGATGWISGLTNVFPRESVTLYKLARAGRMEEAREIYRWFM
PLLRLDTIPTLVQCIKFAEQLAGRGSEQVRMPRMTLIGDERAYVENVVGEAMANRIDLSKYNLD
>Mature_304_residues
MKVNWQGVYPAISTQFNEDGSINFASNTRMLEQLILDGINGIIALGTIGENASLSADEKRAFLKHTVETVAGRIPVIAGC
TENTAQLAIQYVQDVEAIGVDGVMLLPAVVYRGTDREVLTHYQMVARATRLPIMIYNNPVSYGVDINLDMTAILANEPNI
VAIKESTTDTRRLTELQSRFGDRFTLFCGVDDIALESLLLGATGWISGLTNVFPRESVTLYKLARAGRMEEAREIYRWFM
PLLRLDTIPTLVQCIKFAEQLAGRGSEQVRMPRMTLIGDERAYVENVVGEAMANRIDLSKYNLD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=238, Percent_Identity=25.2100840336134, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI13540533, Length=224, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1788823, Length=277, Percent_Identity=31.7689530685921, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082415, Length=275, Percent_Identity=29.4545454545455, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786463, Length=284, Percent_Identity=28.8732394366197, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789620, Length=240, Percent_Identity=28.3333333333333, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33786; Mature: 33786

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNWQGVYPAISTQFNEDGSINFASNTRMLEQLILDGINGIIALGTIGENASLSADEKR
CCCCCCCCCCHHHCCCCCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
AFLKHTVETVAGRIPVIAGCTENTAQLAIQYVQDVEAIGVDGVMLLPAVVYRGTDREVLT
HHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
HYQMVARATRLPIMIYNNPVSYGVDINLDMTAILANEPNIVAIKESTTDTRRLTELQSRF
HHHHHHHHHHCCEEEECCCCCCCEEECCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHC
GDRFTLFCGVDDIALESLLLGATGWISGLTNVFPRESVTLYKLARAGRMEEAREIYRWFM
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
PLLRLDTIPTLVQCIKFAEQLAGRGSEQVRMPRMTLIGDERAYVENVVGEAMANRIDLSK
HHHHHCCHHHHHHHHHHHHHHHCCCCCCEECCCEEEECCCHHHHHHHHHHHHHHHCCCHH
YNLD
CCCC
>Mature Secondary Structure
MKVNWQGVYPAISTQFNEDGSINFASNTRMLEQLILDGINGIIALGTIGENASLSADEKR
CCCCCCCCCCHHHCCCCCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHH
AFLKHTVETVAGRIPVIAGCTENTAQLAIQYVQDVEAIGVDGVMLLPAVVYRGTDREVLT
HHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
HYQMVARATRLPIMIYNNPVSYGVDINLDMTAILANEPNIVAIKESTTDTRRLTELQSRF
HHHHHHHHHHCCEEEECCCCCCCEEECCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHC
GDRFTLFCGVDDIALESLLLGATGWISGLTNVFPRESVTLYKLARAGRMEEAREIYRWFM
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHH
PLLRLDTIPTLVQCIKFAEQLAGRGSEQVRMPRMTLIGDERAYVENVVGEAMANRIDLSK
HHHHHCCHHHHHHHHHHHHHHHCCCCCCEECCCEEEECCCHHHHHHHHHHHHHHHCCCHH
YNLD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]